Rattus norvegicus

0 known processes

Nnt

nicotinamide nucleotide transhydrogenase

(Aliases: MGC109126)

Nnt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 304 0.527
oxoacid metabolic process GO:0043436 290 0.510
organic acid metabolic process GO:0006082 292 0.292
carboxylic acid metabolic process GO:0019752 289 0.281
organic substance catabolic process GO:1901575 316 0.275
dicarboxylic acid metabolic process GO:0043648 42 0.256
catabolic process GO:0009056 351 0.241
single organism catabolic process GO:0044712 283 0.179
energy derivation by oxidation of organic compounds GO:0015980 46 0.173
tissue development GO:0009888 252 0.172
organic acid catabolic process GO:0016054 49 0.166
cellular amino acid metabolic process GO:0006520 107 0.160
carboxylic acid catabolic process GO:0046395 49 0.159
cellular catabolic process GO:0044248 295 0.140
coenzyme metabolic process GO:0006732 86 0.131
response to extracellular stimulus GO:0009991 380 0.121
small molecule catabolic process GO:0044282 59 0.116
lipid catabolic process GO:0016042 46 0.111
cellular component assembly GO:0022607 360 0.110
single organism biosynthetic process GO:0044711 342 0.109
generation of precursor metabolites and energy GO:0006091 62 0.103
tricarboxylic acid metabolic process GO:0072350 10 0.096
branched chain amino acid catabolic process GO:0009083 4 0.095
transcription dna templated GO:0006351 377 0.087
cellular lipid catabolic process GO:0044242 37 0.086
response to glucocorticoid GO:0051384 223 0.073
response to inorganic substance GO:0010035 377 0.071
regulation of cellular ketone metabolic process GO:0010565 27 0.071
cellular ketone metabolic process GO:0042180 51 0.067
cellular amino acid biosynthetic process GO:0008652 32 0.064
alpha amino acid metabolic process GO:1901605 71 0.063
negative regulation of cell death GO:0060548 229 0.063
monocarboxylic acid catabolic process GO:0072329 28 0.060
response to nutrient levels GO:0031667 370 0.060
response to nutrient GO:0007584 248 0.055
negative regulation of cellular metabolic process GO:0031324 281 0.055
regulation of rna metabolic process GO:0051252 391 0.055
cellular component biogenesis GO:0044085 368 0.055
apoptotic process GO:0006915 381 0.054
alpha amino acid catabolic process GO:1901606 20 0.053
neuron development GO:0048666 286 0.053
regulation of cellular amino acid metabolic process GO:0006521 2 0.053
lipid oxidation GO:0034440 30 0.051
nucleoside phosphate metabolic process GO:0006753 283 0.050
regulation of catalytic activity GO:0050790 304 0.050
cofactor metabolic process GO:0051186 95 0.049
regulation of phosphate metabolic process GO:0019220 349 0.049
glycosyl compound metabolic process GO:1901657 182 0.049
cellular response to endogenous stimulus GO:0071495 377 0.049
carbohydrate derivative metabolic process GO:1901135 346 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.048
nucleobase containing small molecule metabolic process GO:0055086 316 0.048
protein complex subunit organization GO:0071822 302 0.048
cellular amine metabolic process GO:0044106 38 0.047
regulation of cellular amine metabolic process GO:0033238 8 0.047
growth GO:0040007 165 0.047
nucleic acid templated transcription GO:0097659 379 0.047
reproductive process GO:0022414 372 0.047
macromolecular complex subunit organization GO:0043933 339 0.046
organophosphate metabolic process GO:0019637 370 0.045
cell projection organization GO:0030030 302 0.045
peptidyl amino acid modification GO:0018193 126 0.045
single organism reproductive process GO:0044702 297 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.043
response to oxygen levels GO:0070482 265 0.043
cellular lipid metabolic process GO:0044255 208 0.043
organic acid biosynthetic process GO:0016053 83 0.043
regulation of transcription dna templated GO:0006355 374 0.042
regulation of protein metabolic process GO:0051246 289 0.042
response to purine containing compound GO:0014074 126 0.042
single organism organelle organization GO:1902589 180 0.042
development of primary sexual characteristics GO:0045137 107 0.040
lipid metabolic process GO:0006629 283 0.040
carboxylic acid biosynthetic process GO:0046394 83 0.040
protein complex assembly GO:0006461 263 0.039
nucleotide metabolic process GO:0009117 279 0.039
regulation of protein modification process GO:0031399 194 0.039
amine metabolic process GO:0009308 38 0.039
regulation of phosphorus metabolic process GO:0051174 349 0.039
ribonucleoside triphosphate metabolic process GO:0009199 141 0.038
programmed cell death GO:0012501 392 0.038
glutamate metabolic process GO:0006536 3 0.038
polysaccharide metabolic process GO:0005976 25 0.038
fatty acid oxidation GO:0019395 29 0.038
positive regulation of signal transduction GO:0009967 175 0.038
rna metabolic process GO:0016070 406 0.037
positive regulation of protein metabolic process GO:0051247 178 0.037
neurological system process GO:0050877 219 0.037
positive regulation of cellular amine metabolic process GO:0033240 3 0.037
regulation of molecular function GO:0065009 398 0.036
carbohydrate metabolic process GO:0005975 130 0.036
macromolecular complex assembly GO:0065003 273 0.036
alpha amino acid biosynthetic process GO:1901607 23 0.036
cellular response to hormone stimulus GO:0032870 247 0.036
cellular response to oxygen containing compound GO:1901701 386 0.035
gonad development GO:0008406 104 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
organonitrogen compound biosynthetic process GO:1901566 167 0.035
regulation of rna biosynthetic process GO:2001141 381 0.035
neuron projection development GO:0031175 273 0.035
protein homooligomerization GO:0051260 91 0.035
reproductive structure development GO:0048608 128 0.034
positive regulation of molecular function GO:0044093 230 0.034
regulation of programmed cell death GO:0043067 341 0.034
regulation of cellular component organization GO:0051128 368 0.034
organelle organization GO:0006996 266 0.033
development of primary female sexual characteristics GO:0046545 56 0.033
response to acid chemical GO:0001101 222 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.033
intracellular signal transduction GO:0035556 314 0.033
regulation of cell differentiation GO:0045595 320 0.033
regulation of apoptotic process GO:0042981 335 0.033
cellular respiration GO:0045333 21 0.032
positive regulation of cell communication GO:0010647 271 0.032
positive regulation of cell death GO:0010942 184 0.032
regulation of hormone levels GO:0010817 187 0.032
cellular response to stress GO:0033554 269 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
aging GO:0007568 241 0.031
response to external biotic stimulus GO:0043207 221 0.031
response to vitamin GO:0033273 131 0.031
single organism carbohydrate metabolic process GO:0044723 118 0.031
rna biosynthetic process GO:0032774 380 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
response to peptide hormone GO:0043434 278 0.031
glycogen metabolic process GO:0005977 23 0.030
head development GO:0060322 247 0.030
negative regulation of apoptotic process GO:0043066 181 0.030
response to bacterium GO:0009617 200 0.030
branched chain amino acid metabolic process GO:0009081 4 0.030
central nervous system development GO:0007417 311 0.030
negative regulation of metabolic process GO:0009892 331 0.029
negative regulation of programmed cell death GO:0043069 183 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
reproductive system development GO:0061458 128 0.028
protein complex biogenesis GO:0070271 263 0.028
cellular response to lipid GO:0071396 201 0.028
female sex differentiation GO:0046660 59 0.028
regulation of membrane potential GO:0042391 110 0.028
response to estradiol GO:0032355 164 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
nucleoside monophosphate metabolic process GO:0009123 93 0.027
cell morphogenesis GO:0000902 142 0.027
ribonucleoside metabolic process GO:0009119 174 0.026
positive regulation of programmed cell death GO:0043068 157 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
secretion GO:0046903 307 0.026
monosaccharide metabolic process GO:0005996 61 0.026
brain development GO:0007420 247 0.026
neuron differentiation GO:0030182 368 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
regulation of cellular localization GO:0060341 263 0.026
organic anion transport GO:0015711 132 0.026
positive regulation of protein modification process GO:0031401 142 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
multicellular organism reproduction GO:0032504 233 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
developmental process involved in reproduction GO:0003006 159 0.025
cell part morphogenesis GO:0032990 123 0.025
positive regulation of lipid catabolic process GO:0050996 4 0.025
regulation of signal transduction GO:0009966 318 0.025
anatomical structure morphogenesis GO:0009653 298 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
positive regulation of biosynthetic process GO:0009891 319 0.023
protein oligomerization GO:0051259 191 0.023
cell cell signaling GO:0007267 335 0.023
lipid modification GO:0030258 52 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
cellular polysaccharide metabolic process GO:0044264 23 0.023
response to ethanol GO:0045471 162 0.023
female gonad development GO:0008585 53 0.023
response to growth factor GO:0070848 189 0.023
cellular response to growth factor stimulus GO:0071363 162 0.022
response to corticosteroid GO:0031960 235 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.021
nitrogen compound transport GO:0071705 229 0.021
cellular glucan metabolic process GO:0006073 23 0.021
lipid biosynthetic process GO:0008610 128 0.021
response to lipopolysaccharide GO:0032496 191 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
glycogen biosynthetic process GO:0005978 15 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
cellular response to organonitrogen compound GO:0071417 197 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
regulation of transferase activity GO:0051338 123 0.020
response to hypoxia GO:0001666 231 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
response to fatty acid GO:0070542 65 0.020
response to peptide GO:1901652 292 0.020
sex differentiation GO:0007548 113 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
nucleoside metabolic process GO:0009116 179 0.020
fatty acid beta oxidation GO:0006635 22 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
response to oxidative stress GO:0006979 186 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
purine containing compound metabolic process GO:0072521 253 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
gastrulation GO:0007369 2 0.019
reproduction GO:0000003 245 0.019
response to carbohydrate GO:0009743 183 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
hexose metabolic process GO:0019318 58 0.018
purine nucleoside monophosphate metabolic process GO:0009126 84 0.018
carboxylic acid transport GO:0046942 115 0.018
anion transport GO:0006820 178 0.018
negative regulation of gene expression GO:0010629 199 0.018
protein phosphorylation GO:0006468 345 0.018
regulation of secretion GO:0051046 224 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
blood circulation GO:0008015 183 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
positive regulation of fatty acid beta oxidation GO:0032000 4 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
response to decreased oxygen levels GO:0036293 237 0.017
fatty acid catabolic process GO:0009062 26 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
regulation of kinase activity GO:0043549 117 0.017
positive regulation of signaling GO:0023056 270 0.017
response to other organism GO:0051707 220 0.017
secretion by cell GO:0032940 248 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
cellular chemical homeostasis GO:0055082 247 0.017
regulation of catabolic process GO:0009894 113 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
valine metabolic process GO:0006573 1 0.017
cellular cation homeostasis GO:0030003 180 0.016
chemical homeostasis GO:0048878 292 0.016
regulation of cell projection organization GO:0031344 175 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
fatty acid metabolic process GO:0006631 99 0.016
regulation of phosphorylation GO:0042325 248 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
response to biotic stimulus GO:0009607 226 0.016
positive regulation of developmental process GO:0051094 283 0.016
positive regulation of response to stimulus GO:0048584 285 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of gene expression GO:0010628 244 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
regulation of cell proliferation GO:0042127 359 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
hormone metabolic process GO:0042445 69 0.015
organic acid transport GO:0015849 116 0.015
regulation of cell development GO:0060284 263 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
regulation of secretion by cell GO:1903530 208 0.015
behavior GO:0007610 205 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
cellular response to acid chemical GO:0071229 75 0.015
muscle structure development GO:0061061 87 0.014
regulation of hormone secretion GO:0046883 106 0.014
intracellular transport GO:0046907 185 0.014
response to ketone GO:1901654 182 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
cellular homeostasis GO:0019725 252 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
regulation of nervous system development GO:0051960 264 0.014
regulation of protein kinase activity GO:0045859 105 0.014
regulation of peptide transport GO:0090087 87 0.014
chromosome segregation GO:0007059 2 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
tube development GO:0035295 89 0.014
glucan metabolic process GO:0044042 23 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
single organism behavior GO:0044708 130 0.014
regulation of organelle organization GO:0033043 80 0.014
tricarboxylic acid cycle GO:0006099 11 0.013
cell projection morphogenesis GO:0048858 123 0.013
single organism cellular localization GO:1902580 102 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
small molecule biosynthetic process GO:0044283 124 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
learning or memory GO:0007611 90 0.013
circulatory system development GO:0072359 134 0.013
gland development GO:0048732 155 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of system process GO:0044057 208 0.013
response to metal ion GO:0010038 253 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
amide transport GO:0042886 105 0.013
glial cell differentiation GO:0010001 65 0.013
positive regulation of fatty acid oxidation GO:0046321 6 0.013
camera type eye development GO:0043010 48 0.013
response to hexose GO:0009746 144 0.013
regulation of neuron differentiation GO:0045664 208 0.013
regulation of neurogenesis GO:0050767 247 0.013
peroxisome organization GO:0007031 6 0.013
acetyl coa metabolic process GO:0006084 17 0.013
urogenital system development GO:0001655 78 0.013
cellular response to oxidative stress GO:0034599 76 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
anterior posterior pattern specification GO:0009952 1 0.012
peptidyl glutamic acid modification GO:0018200 1 0.012
energy reserve metabolic process GO:0006112 25 0.012
protein targeting GO:0006605 61 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
response to temperature stimulus GO:0009266 94 0.012
multicellular organismal signaling GO:0035637 44 0.012
response to toxic substance GO:0009636 133 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
lipid localization GO:0010876 62 0.012
embryonic pattern specification GO:0009880 1 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
regulation of homeostatic process GO:0032844 101 0.012
gliogenesis GO:0042063 93 0.012
response to radiation GO:0009314 137 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
regulation of peptide secretion GO:0002791 82 0.012
hormone secretion GO:0046879 115 0.012
regulation of hydrolase activity GO:0051336 143 0.012
ossification GO:0001503 70 0.011
muscle system process GO:0003012 115 0.011
neuronal action potential GO:0019228 35 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.011
response to wounding GO:0009611 254 0.011
hormone transport GO:0009914 121 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
developmental growth GO:0048589 100 0.011
response to monosaccharide GO:0034284 159 0.011
neuron death GO:0070997 127 0.011
ras protein signal transduction GO:0007265 29 0.011
action potential GO:0001508 54 0.011
long chain fatty acid metabolic process GO:0001676 32 0.011
glycerolipid metabolic process GO:0046486 67 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
axis specification GO:0009798 4 0.011
heart morphogenesis GO:0003007 3 0.011
positive regulation of catabolic process GO:0009896 78 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
neuron apoptotic process GO:0051402 88 0.011
response to glucose GO:0009749 136 0.011
glucan biosynthetic process GO:0009250 15 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
response to alkaloid GO:0043279 132 0.011
actin filament based process GO:0030029 86 0.011
signal release GO:0023061 145 0.011
regulation of ion transport GO:0043269 245 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.010
nucleoside catabolic process GO:0009164 126 0.010
peptide transport GO:0015833 97 0.010
multi organism reproductive process GO:0044703 262 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
nucleoside monophosphate biosynthetic process GO:0009124 28 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
rhythmic process GO:0048511 156 0.010
amino acid betaine metabolic process GO:0006577 3 0.010
citrate metabolic process GO:0006101 3 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
transmission of nerve impulse GO:0019226 42 0.010
peptide secretion GO:0002790 86 0.010
cellular response to tumor necrosis factor GO:0071356 46 0.010

Nnt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.057
inherited metabolic disorder DOID:655 0 0.057
amino acid metabolic disorder DOID:9252 0 0.030
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.018
central nervous system disease DOID:331 0 0.016
brain disease DOID:936 0 0.016
organic acidemia DOID:0060159 0 0.015