Rattus norvegicus

117 known processes

Nolc1

nucleolar and coiled-body phosphoprotein 1

(Aliases: Nopp140)

Nolc1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.229
single organism biosynthetic process GO:0044711 342 0.157
purine containing compound biosynthetic process GO:0072522 85 0.140
alpha amino acid biosynthetic process GO:1901607 23 0.106
reproduction GO:0000003 245 0.103
negative regulation of rna splicing GO:0033119 3 0.099
nucleoside phosphate biosynthetic process GO:1901293 102 0.099
organ regeneration GO:0031100 101 0.095
spindle organization GO:0007051 2 0.094
regulation of cell proliferation GO:0042127 359 0.090
alternative mrna splicing via spliceosome GO:0000380 4 0.087
nucleotide metabolic process GO:0009117 279 0.086
macromolecular complex subunit organization GO:0043933 339 0.079
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.079
small molecule biosynthetic process GO:0044283 124 0.078
ribose phosphate biosynthetic process GO:0046390 87 0.072
organonitrogen compound biosynthetic process GO:1901566 167 0.072
locomotion GO:0040011 237 0.071
organelle organization GO:0006996 266 0.069
Mouse
negative regulation of cell death GO:0060548 229 0.063
ribonucleotide biosynthetic process GO:0009260 85 0.062
organophosphate biosynthetic process GO:0090407 143 0.059
cellular amino acid biosynthetic process GO:0008652 32 0.058
protein tetramerization GO:0051262 38 0.057
alpha amino acid metabolic process GO:1901605 71 0.055
rna biosynthetic process GO:0032774 380 0.055
chromosome segregation GO:0007059 2 0.054
nucleotide biosynthetic process GO:0009165 98 0.054
nucleoside monophosphate biosynthetic process GO:0009124 28 0.053
secretion GO:0046903 307 0.052
tetrahydrofolate metabolic process GO:0046653 9 0.049
anatomical structure morphogenesis GO:0009653 298 0.047
cell cycle GO:0007049 101 0.046
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.046
cellular component biogenesis GO:0044085 368 0.045
nucleic acid templated transcription GO:0097659 379 0.042
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.042
oxoacid metabolic process GO:0043436 290 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
single organism reproductive process GO:0044702 297 0.038
coenzyme metabolic process GO:0006732 86 0.038
folic acid containing compound metabolic process GO:0006760 10 0.038
protein phosphorylation GO:0006468 345 0.038
organic acid metabolic process GO:0006082 292 0.038
transcription dna templated GO:0006351 377 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
macromolecular complex assembly GO:0065003 273 0.037
cofactor metabolic process GO:0051186 95 0.035
reproductive process GO:0022414 372 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
cellular component assembly GO:0022607 360 0.034
regulation of catalytic activity GO:0050790 304 0.034
oxidation reduction process GO:0055114 304 0.033
purine ribonucleoside biosynthetic process GO:0046129 21 0.033
ribonucleoside biosynthetic process GO:0042455 25 0.032
protein complex subunit organization GO:0071822 302 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.030
purine ribonucleotide biosynthetic process GO:0009152 81 0.030
regeneration GO:0031099 163 0.029
serine family amino acid metabolic process GO:0009069 12 0.029
organelle fission GO:0048285 25 0.028
cellular catabolic process GO:0044248 295 0.028
positive regulation of gene expression GO:0010628 244 0.028
negative regulation of mrna splicing via spliceosome GO:0048025 2 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
regulation of protein metabolic process GO:0051246 289 0.026
transmembrane transport GO:0055085 412 0.026
cell cell signaling GO:0007267 335 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
regulation of mrna splicing via spliceosome GO:0048024 3 0.026
embryo development GO:0009790 49 0.025
organic substance catabolic process GO:1901575 316 0.025
protein complex biogenesis GO:0070271 263 0.025
purine nucleotide biosynthetic process GO:0006164 83 0.024
response to peptide GO:1901652 292 0.024
protein complex assembly GO:0006461 263 0.024
ribonucleoprotein complex biogenesis GO:0022613 10 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.024
ribonucleoside monophosphate metabolic process GO:0009161 88 0.024
gamete generation GO:0007276 124 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
defense response GO:0006952 194 0.023
response to increased oxygen levels GO:0036296 45 0.022
chromosome organization GO:0051276 36 0.021
response to peptide hormone GO:0043434 278 0.021
carboxylic acid catabolic process GO:0046395 49 0.021
positive regulation of developmental process GO:0051094 283 0.021
rhythmic process GO:0048511 156 0.021
multi organism reproductive process GO:0044703 262 0.021
axis specification GO:0009798 4 0.021
regulation of secretion by cell GO:1903530 208 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
forebrain development GO:0030900 98 0.020
reproductive structure development GO:0048608 128 0.020
regulation of cell differentiation GO:0045595 320 0.019
negative regulation of metabolic process GO:0009892 331 0.019
kidney mesenchyme development GO:0072074 2 0.019
multicellular organism reproduction GO:0032504 233 0.019
catabolic process GO:0009056 351 0.019
regulation of apoptotic process GO:0042981 335 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
hepaticobiliary system development GO:0061008 90 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.019
nucleoside biosynthetic process GO:0009163 25 0.019
amine metabolic process GO:0009308 38 0.018
response to extracellular stimulus GO:0009991 380 0.018
ncrna processing GO:0034470 3 0.018
regulation of organelle organization GO:0033043 80 0.018
anion transport GO:0006820 178 0.018
mrna splicing via spliceosome GO:0000398 7 0.018
organophosphate metabolic process GO:0019637 370 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
purine containing compound metabolic process GO:0072521 253 0.017
negative regulation of developmental process GO:0051093 125 0.017
homeostatic process GO:0042592 331 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
negative regulation of cell cycle phase transition GO:1901988 4 0.017
meiotic chromosome segregation GO:0045132 1 0.017
alpha amino acid catabolic process GO:1901606 20 0.016
localization of cell GO:0051674 202 0.016
cellular amino acid catabolic process GO:0009063 21 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
embryonic axis specification GO:0000578 1 0.016
immune system process GO:0002376 204 0.016
regulation of hormone levels GO:0010817 187 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
meiosis i GO:0007127 2 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
regulation of response to stress GO:0080134 126 0.016
nucleoside monophosphate metabolic process GO:0009123 93 0.016
gland development GO:0048732 155 0.016
cellular metal ion homeostasis GO:0006875 172 0.015
negative regulation of gene expression GO:0010629 199 0.015
ion transmembrane transport GO:0034220 365 0.015
glutamine family amino acid metabolic process GO:0009064 15 0.015
response to gamma radiation GO:0010332 24 0.015
cellular response to stress GO:0033554 269 0.015
mesoderm morphogenesis GO:0048332 1 0.015
formation of primary germ layer GO:0001704 1 0.015
positive regulation of protein modification process GO:0031401 142 0.015
monosaccharide metabolic process GO:0005996 61 0.014
intracellular signal transduction GO:0035556 314 0.014
programmed cell death GO:0012501 392 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
response to nutrient levels GO:0031667 370 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
small molecule catabolic process GO:0044282 59 0.014
hormone transport GO:0009914 121 0.014
regulation of cell cycle GO:0051726 73 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
organic acid catabolic process GO:0016054 49 0.014
ribonucleoside monophosphate biosynthetic process GO:0009156 24 0.013
rna splicing GO:0008380 11 0.013
detection of stimulus GO:0051606 24 0.013
cerebral cortex development GO:0021987 18 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
cellular component movement GO:0006928 248 0.013
regulation of molecular function GO:0065009 398 0.013
secretion by cell GO:0032940 248 0.013
regulation of transcription dna templated GO:0006355 374 0.013
reproductive system development GO:0061458 128 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
circulatory system development GO:0072359 134 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.013
response to inorganic substance GO:0010035 377 0.013
protein oligomerization GO:0051259 191 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of body fluid levels GO:0050878 90 0.012
mrna metabolic process GO:0016071 20 0.012
purine nucleoside biosynthetic process GO:0042451 21 0.012
signal release GO:0023061 145 0.012
nitrogen compound transport GO:0071705 229 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
fertilization GO:0009566 3 0.012
positive regulation of atp biosynthetic process GO:2001171 2 0.012
regulation of meiotic cell cycle GO:0051445 3 0.012
calcium ion homeostasis GO:0055074 162 0.012
cell cycle process GO:0022402 57 0.012
cellular homeostasis GO:0019725 252 0.012
head development GO:0060322 247 0.012
chemical homeostasis GO:0048878 292 0.011
cellular macromolecule catabolic process GO:0044265 29 0.011
nucleoside metabolic process GO:0009116 179 0.011
macromolecule localization GO:0033036 252 0.011
regulation of cell cycle process GO:0010564 31 0.011
learning or memory GO:0007611 90 0.011
amp metabolic process GO:0046033 8 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of metanephros development GO:0072215 4 0.011
single organism cellular localization GO:1902580 102 0.011
regulation of rna stability GO:0043487 3 0.011
rna stabilization GO:0043489 2 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
response to hyperoxia GO:0055093 45 0.011
liver development GO:0001889 90 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.010
glycosyl compound biosynthetic process GO:1901659 25 0.010
developmental growth GO:0048589 100 0.010
metanephric mesenchyme development GO:0072075 2 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
proteolysis GO:0006508 175 0.010
anterior posterior pattern specification GO:0009952 1 0.010
rrna processing GO:0006364 2 0.010
apoptotic process GO:0006915 381 0.010
single organism carbohydrate catabolic process GO:0044724 40 0.010

Nolc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.043
disease of anatomical entity DOID:7 0 0.043
central nervous system disease DOID:331 0 0.043
disease of cellular proliferation DOID:14566 0 0.016
gastrointestinal system disease DOID:77 0 0.015
sensory system disease DOID:0050155 0 0.010