Rattus norvegicus

149 known processes

Nos3

nitric oxide synthase 3, endothelial cell

(Aliases: eNos)

Nos3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.605
anatomical structure morphogenesis GO:0009653 298 0.531
Mouse
tissue development GO:0009888 252 0.529
intracellular signal transduction GO:0035556 314 0.498
Rat
response to mechanical stimulus GO:0009612 134 0.486
negative regulation of response to stimulus GO:0048585 155 0.454
Mouse
cellular component movement GO:0006928 248 0.442
Human
negative regulation of multicellular organismal process GO:0051241 203 0.421
Mouse Rat
blood circulation GO:0008015 183 0.416
Human Mouse Rat Fly
response to hypoxia GO:0001666 231 0.412
homeostatic process GO:0042592 331 0.396
Rat
regulation of cellular component organization GO:0051128 368 0.381
response to decreased oxygen levels GO:0036293 237 0.373
lymphoid progenitor cell differentiation GO:0002320 2 0.371
blood vessel morphogenesis GO:0048514 58 0.369
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 83 0.352
Mouse
regulation of molecular function GO:0065009 398 0.352
Human Mouse Rat
response to nutrient GO:0007584 248 0.342
Rat
blood vessel development GO:0001568 69 0.339
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.329
Human Rat
negative regulation of signaling GO:0023057 157 0.323
Rat
response to extracellular stimulus GO:0009991 380 0.318
Rat
regulation of intracellular signal transduction GO:1902531 218 0.316
positive regulation of phosphorus metabolic process GO:0010562 262 0.305
Human
regulation of cellular component movement GO:0051270 150 0.293
regulation of system process GO:0044057 208 0.286
Mouse Rat Fly
apoptotic process GO:0006915 381 0.270
positive regulation of multicellular organismal process GO:0051240 387 0.261
Mouse Rat
pro t cell differentiation GO:0002572 1 0.258
myeloid progenitor cell differentiation GO:0002318 1 0.257
cellular response to cytokine stimulus GO:0071345 127 0.256
cation transport GO:0006812 382 0.256
Mouse Rat
programmed cell death GO:0012501 392 0.251
cellular component assembly GO:0022607 360 0.250
circulatory system development GO:0072359 134 0.246
Mouse
negative regulation of organ growth GO:0046621 3 0.235
regulation of cell growth GO:0001558 85 0.232
regulation of protein metabolic process GO:0051246 289 0.222
Rat
cellular metal ion homeostasis GO:0006875 172 0.220
Rat
response to cytokine GO:0034097 215 0.219
response to estrogen GO:0043627 232 0.216
response to fluid shear stress GO:0034405 16 0.215
Human
cellular response to oxygen containing compound GO:1901701 386 0.206
cellular calcium ion homeostasis GO:0006874 160 0.205
Rat
potassium ion transport GO:0006813 97 0.202
Mouse
actin filament based process GO:0030029 86 0.201
heart contraction GO:0060047 57 0.197
Mouse Rat Fly
multi organism reproductive process GO:0044703 262 0.194
positive regulation of response to stimulus GO:0048584 285 0.190
defense response GO:0006952 194 0.189
Rat
ribonucleotide metabolic process GO:0009259 231 0.188
Human
positive regulation of cellular component organization GO:0051130 200 0.183
regulation of nucleotide metabolic process GO:0006140 117 0.178
Human
negative regulation of developmental process GO:0051093 125 0.178
purine nucleoside triphosphate catabolic process GO:0009146 122 0.177
s shaped body morphogenesis GO:0072050 2 0.176
positive regulation of phosphate metabolic process GO:0045937 262 0.174
Human
cardiovascular system development GO:0072358 134 0.172
Mouse
negative regulation of growth GO:0045926 37 0.172
gland development GO:0048732 155 0.171
regulation of vasculature development GO:1901342 44 0.171
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.169
Rat
single organism reproductive process GO:0044702 297 0.168
Mouse
response to oxygen levels GO:0070482 265 0.165
cellular response to endogenous stimulus GO:0071495 377 0.164
regulation of organ growth GO:0046620 13 0.164
organelle organization GO:0006996 266 0.164
divalent inorganic cation transport GO:0072511 134 0.162
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.160
Human
regulation of ion transport GO:0043269 245 0.160
Mouse Rat
nucleoside phosphate metabolic process GO:0006753 283 0.159
Human
carbohydrate derivative metabolic process GO:1901135 346 0.157
Human Rat
endothelium development GO:0003158 12 0.155
reproductive process GO:0022414 372 0.152
regulation of neurogenesis GO:0050767 247 0.150
cytoskeleton organization GO:0007010 111 0.149
muscle system process GO:0003012 115 0.149
Mouse
female pregnancy GO:0007565 122 0.148
oxoacid metabolic process GO:0043436 290 0.147
Human Rat
cellular ion homeostasis GO:0006873 184 0.147
Rat
cellular component biogenesis GO:0044085 368 0.145
regulation of blood vessel size GO:0050880 89 0.145
Mouse Rat
epithelial cell differentiation GO:0030855 71 0.144
cellular cation homeostasis GO:0030003 180 0.143
Rat
regulation of blood pressure GO:0008217 83 0.143
Human Rat
regulation of nervous system development GO:0051960 264 0.142
regulation of tube size GO:0035150 89 0.142
Mouse Rat
regulation of signal transduction GO:0009966 318 0.140
purine ribonucleotide biosynthetic process GO:0009152 81 0.140
Human
localization of cell GO:0051674 202 0.138
Human
signal transduction by phosphorylation GO:0023014 144 0.138
muscle structure development GO:0061061 87 0.138
carbohydrate derivative biosynthetic process GO:1901137 124 0.136
Human
regulation of multicellular organismal development GO:2000026 376 0.135
Mouse
negative regulation of apoptotic process GO:0043066 181 0.135
Rat
calcium ion homeostasis GO:0055074 162 0.134
Rat
organic substance catabolic process GO:1901575 316 0.133
Human Rat
actin cytoskeleton organization GO:0030036 73 0.131
positive regulation of cell differentiation GO:0045597 217 0.130
negative regulation of cell communication GO:0010648 158 0.130
Rat
regulation of blood circulation GO:1903522 110 0.130
Mouse Rat Fly
positive regulation of cell motility GO:2000147 97 0.129
negative regulation of programmed cell death GO:0043069 183 0.129
Rat
regulation of anatomical structure size GO:0090066 135 0.129
Mouse Rat
cell motility GO:0048870 202 0.129
Human
regulation of anatomical structure morphogenesis GO:0022603 141 0.128
Mouse
cellular homeostasis GO:0019725 252 0.128
Rat
negative regulation of cell proliferation GO:0008285 119 0.127
renal system development GO:0072001 67 0.126
response to growth factor GO:0070848 189 0.126
positive regulation of signal transduction GO:0009967 175 0.125
circulatory system process GO:0003013 183 0.125
Human Mouse Rat Fly
glycosaminoglycan biosynthetic process GO:0006024 4 0.123
response to inorganic substance GO:0010035 377 0.121
growth GO:0040007 165 0.121
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.120
Human
negative regulation of cell death GO:0060548 229 0.119
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.117
single organism behavior GO:0044708 130 0.115
Rat
immune system process GO:0002376 204 0.114
heart development GO:0007507 72 0.112
nucleobase containing small molecule metabolic process GO:0055086 316 0.112
Human
metal ion homeostasis GO:0055065 186 0.111
Rat
mesoderm development GO:0007498 2 0.111
cell cell signaling GO:0007267 335 0.111
Rat
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.111
regulation of phosphate metabolic process GO:0019220 349 0.109
Human Rat
nitrogen compound transport GO:0071705 229 0.109
Rat
secretion GO:0046903 307 0.108
Rat
positive regulation of programmed cell death GO:0043068 157 0.108
regulation of cellular ketone metabolic process GO:0010565 27 0.106
organic acid metabolic process GO:0006082 292 0.106
Human Rat
response to peptide hormone GO:0043434 278 0.105
response to wounding GO:0009611 254 0.104
transmembrane transport GO:0055085 412 0.104
Rat
regulation of muscle contraction GO:0006937 53 0.103
organ regeneration GO:0031100 101 0.102
secretion by cell GO:0032940 248 0.102
Rat
regulation of neuron differentiation GO:0045664 208 0.100
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.099
Human
cellular response to stress GO:0033554 269 0.099
neuron differentiation GO:0030182 368 0.099
organ growth GO:0035265 24 0.099
locomotion GO:0040011 237 0.098
Human
response to nutrient levels GO:0031667 370 0.097
Rat
response to biotic stimulus GO:0009607 226 0.096
regulation of cell development GO:0060284 263 0.096
regulation of growth GO:0040008 105 0.096
regulation of cell differentiation GO:0045595 320 0.095
cation homeostasis GO:0055080 195 0.095
Rat
cell growth GO:0016049 104 0.094
response to carbohydrate GO:0009743 183 0.094
regulation of cardiac muscle tissue development GO:0055024 12 0.094
cardiac muscle tissue growth GO:0055017 20 0.093
regulation of phosphorylation GO:0042325 248 0.093
Rat
positive regulation of cell development GO:0010720 176 0.093
cardiac muscle cell development GO:0055013 16 0.092
vasculogenesis GO:0001570 3 0.092
vascular process in circulatory system GO:0003018 96 0.091
Mouse Rat
response to corticosteroid GO:0031960 235 0.091
purine containing compound metabolic process GO:0072521 253 0.091
Human
kidney development GO:0001822 67 0.090
macromolecule localization GO:0033036 252 0.089
cellular response to external stimulus GO:0071496 118 0.089
positive regulation of molecular function GO:0044093 230 0.089
Human
cellular response to abiotic stimulus GO:0071214 85 0.089
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.088
regulation of b cell differentiation GO:0045577 1 0.088
regulation of homeostatic process GO:0032844 101 0.088
nucleotide metabolic process GO:0009117 279 0.088
Human
response to molecule of bacterial origin GO:0002237 194 0.088
glycosyl compound metabolic process GO:1901657 182 0.087
Rat
cellular chemical homeostasis GO:0055082 247 0.087
Rat
cellular ketone metabolic process GO:0042180 51 0.086
positive regulation of cell communication GO:0010647 271 0.086
Rat
regulation of secretion by cell GO:1903530 208 0.086
Rat
protein complex subunit organization GO:0071822 302 0.086
positive regulation of lipid kinase activity GO:0090218 2 0.085
cell migration GO:0016477 197 0.085
Human
multi multicellular organism process GO:0044706 138 0.084
positive regulation of transport GO:0051050 245 0.084
Rat
behavior GO:0007610 205 0.084
Rat
divalent metal ion transport GO:0070838 132 0.084
Mouse
ribose phosphate metabolic process GO:0019693 235 0.083
Human
response to monosaccharide GO:0034284 159 0.083
regulation of cardiac muscle contraction GO:0055117 17 0.083
positive regulation of developmental process GO:0051094 283 0.082
Mouse
negative regulation of cell differentiation GO:0045596 99 0.081
regulation of membrane potential GO:0042391 110 0.081
multicellular organism reproduction GO:0032504 233 0.080
Mouse
carboxylic acid metabolic process GO:0019752 289 0.080
Human Rat
multicellular organism growth GO:0035264 1 0.080
aging GO:0007568 241 0.080
divalent inorganic cation homeostasis GO:0072507 165 0.080
Rat
ion transmembrane transport GO:0034220 365 0.080
Rat
positive regulation of blood circulation GO:1903524 65 0.079
Rat
organophosphate biosynthetic process GO:0090407 143 0.079
Human
purine ribonucleotide metabolic process GO:0009150 227 0.078
Human
purine nucleotide metabolic process GO:0006163 229 0.078
Human
purine ribonucleoside metabolic process GO:0046128 168 0.077
regulation of protein phosphorylation GO:0001932 183 0.077
Rat
cardiac muscle cell contraction GO:0086003 10 0.077
organophosphate metabolic process GO:0019637 370 0.076
Human
chemical homeostasis GO:0048878 292 0.076
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.076
Rat
regulation of nucleotide biosynthetic process GO:0030808 47 0.075
Human
ras protein signal transduction GO:0007265 29 0.075
neurological system process GO:0050877 219 0.075
Rat
positive regulation of cell proliferation GO:0008284 249 0.075
positive regulation of phosphorylation GO:0042327 177 0.075
developmental growth GO:0048589 100 0.074
regulation of purine nucleotide metabolic process GO:1900542 115 0.074
Human
purine nucleoside metabolic process GO:0042278 169 0.074
regulation of catalytic activity GO:0050790 304 0.074
Human Mouse Rat
metanephric mesenchymal cell migration GO:0035789 2 0.073
negative regulation of metabolic process GO:0009892 331 0.073
Mouse Rat
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.073
regulation of apoptotic process GO:0042981 335 0.072
positive regulation of protein phosphorylation GO:0001934 135 0.072
response to estradiol GO:0032355 164 0.072
positive regulation of cell migration GO:0030335 96 0.072
regulation of cellular localization GO:0060341 263 0.072
Rat
negative regulation of transport GO:0051051 136 0.072
Mouse Rat
skeletal muscle tissue development GO:0007519 31 0.072
single organism organelle organization GO:1902589 180 0.071
heart growth GO:0060419 20 0.071
response to glucose GO:0009749 136 0.071
muscle cell proliferation GO:0033002 84 0.071
regulation of striated muscle contraction GO:0006942 21 0.070
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.069
regulation of behavior GO:0050795 61 0.069
vasoconstriction GO:0042310 54 0.069
Rat
protein localization GO:0008104 191 0.069
nucleotide biosynthetic process GO:0009165 98 0.069
Human
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.069
response to glucocorticoid GO:0051384 223 0.068
lymphocyte activation GO:0046649 43 0.068
regulation of catabolic process GO:0009894 113 0.068
cardiocyte differentiation GO:0035051 22 0.067
protein phosphorylation GO:0006468 345 0.067
Rat
multicellular organismal reproductive process GO:0048609 233 0.067
Mouse
cell chemotaxis GO:0060326 31 0.067
positive regulation of biosynthetic process GO:0009891 319 0.066
Human
synaptic transmission GO:0007268 235 0.066
organonitrogen compound biosynthetic process GO:1901566 167 0.066
Human
regulation of angiogenesis GO:0045765 39 0.066
Mouse
regulation of metal ion transport GO:0010959 118 0.065
Mouse Rat
cardiac muscle cell proliferation GO:0060038 6 0.065
tissue remodeling GO:0048771 40 0.065
Mouse Rat
kidney morphogenesis GO:0060993 13 0.065
immunoglobulin mediated immune response GO:0016064 4 0.065
positive regulation of signaling GO:0023056 270 0.065
Rat
regulation of immune system process GO:0002682 123 0.065
regulation of cellular catabolic process GO:0031329 101 0.064
regulation of camp biosynthetic process GO:0030817 38 0.064
regeneration GO:0031099 163 0.064
response to alkaloid GO:0043279 132 0.064
Rat
ion homeostasis GO:0050801 212 0.062
Rat
positive regulation of locomotion GO:0040017 102 0.062
regulation of developmental growth GO:0048638 45 0.062
regulation of programmed cell death GO:0043067 341 0.062
purine nucleotide biosynthetic process GO:0006164 83 0.062
Human
regulation of heart growth GO:0060420 12 0.062
cellular amino acid metabolic process GO:0006520 107 0.061
Human Rat
cellular response to nitrogen compound GO:1901699 210 0.061
ribose phosphate biosynthetic process GO:0046390 87 0.061
Human
response to ketone GO:1901654 182 0.061
gastrulation GO:0007369 2 0.060
nucleoside triphosphate catabolic process GO:0009143 123 0.060
salivary gland morphogenesis GO:0007435 1 0.059
positive regulation of catalytic activity GO:0043085 184 0.059
Human
calcium ion transport GO:0006816 131 0.059
Mouse
negative regulation of nervous system development GO:0051961 79 0.058
positive regulation of immune system process GO:0002684 90 0.058
kidney mesenchyme development GO:0072074 2 0.058
b cell differentiation GO:0030183 2 0.058
metanephric comma shaped body morphogenesis GO:0072278 2 0.058
positive regulation of cellular biosynthetic process GO:0031328 295 0.057
Human
response to metal ion GO:0010038 253 0.057
negative regulation of cell development GO:0010721 82 0.057
reproduction GO:0000003 245 0.057
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.057
negative regulation of osteoblast differentiation GO:0045668 2 0.057
metal ion transport GO:0030001 289 0.057
Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.056
monovalent inorganic cation transport GO:0015672 172 0.056
Mouse Rat
mapk cascade GO:0000165 140 0.056
regulation of immunoglobulin mediated immune response GO:0002889 2 0.055
heart morphogenesis GO:0003007 3 0.055
response to purine containing compound GO:0014074 126 0.055
positive regulation of epidermis development GO:0045684 1 0.054
regulation of cellular amine metabolic process GO:0033238 8 0.054
single organism catabolic process GO:0044712 283 0.054
Human Rat
regulation of calcium ion transport GO:0051924 77 0.054
Mouse
muscle contraction GO:0006936 88 0.054
nucleoside phosphate biosynthetic process GO:1901293 102 0.054
Human
cardiac muscle contraction GO:0060048 27 0.054
b cell mediated immunity GO:0019724 4 0.053
digestive tract development GO:0048565 39 0.053
nucleoside metabolic process GO:0009116 179 0.053
cell differentiation involved in kidney development GO:0061005 4 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.053
positive regulation of nucleotide metabolic process GO:0045981 91 0.052
Human
negative regulation of molecular function GO:0044092 133 0.052
Mouse
catabolic process GO:0009056 351 0.052
Human Rat
sensory perception GO:0007600 101 0.052
Rat
response to interleukin 1 GO:0070555 55 0.052
Rat
small gtpase mediated signal transduction GO:0007264 36 0.052
negative regulation of macromolecule metabolic process GO:0010605 260 0.052
Rat
renal system process GO:0003014 40 0.051
cell migration involved in kidney development GO:0035787 2 0.051
regulation of immunoglobulin production GO:0002637 4 0.051
muscle tissue development GO:0060537 58 0.051
regulation of cell morphogenesis GO:0022604 77 0.051
metanephric mesenchyme development GO:0072075 2 0.050
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.050
positive regulation of gene expression GO:0010628 244 0.050
reproductive system development GO:0061458 128 0.049
Mouse
regulation of muscle tissue development GO:1901861 25 0.049
regulation of locomotion GO:0040012 148 0.049
striated muscle cell development GO:0055002 26 0.049
epithelial cell proliferation GO:0050673 54 0.049
Rat
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.049
ribonucleoside metabolic process GO:0009119 174 0.049
cellular response to glucocorticoid stimulus GO:0071385 68 0.049
heart process GO:0003015 57 0.049
Mouse Rat Fly
rna metabolic process GO:0016070 406 0.049
protein complex assembly GO:0006461 263 0.048
negative regulation of protein metabolic process GO:0051248 114 0.048
Rat
regulation of actin filament based movement GO:1903115 12 0.048
urogenital system development GO:0001655 78 0.048
positive regulation of vasodilation GO:0045909 29 0.048
Rat
negative regulation of heart growth GO:0061117 3 0.047
organic anion transport GO:0015711 132 0.047
striated muscle tissue development GO:0014706 58 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
chemotaxis GO:0006935 66 0.047
coronary vasculature morphogenesis GO:0060977 3 0.047
regulation of cellular response to growth factor stimulus GO:0090287 15 0.046
cellular response to hormone stimulus GO:0032870 247 0.046
negative regulation of signal transduction GO:0009968 83 0.046
regulation of transcription regulatory region dna binding GO:2000677 4 0.046
regulation of fat cell differentiation GO:0045598 3 0.046
vasculature development GO:0001944 70 0.045
Mouse
negative regulation of response to external stimulus GO:0032102 37 0.045
positive regulation of cellular protein metabolic process GO:0032270 167 0.045
morphogenesis of an epithelium GO:0002009 20 0.045
ovulation cycle process GO:0022602 50 0.045
Mouse
positive regulation of hydrolase activity GO:0051345 86 0.045
positive regulation of immunoglobulin production GO:0002639 4 0.045
ribonucleotide biosynthetic process GO:0009260 85 0.044
Human
regulation of mesenchymal cell proliferation GO:0010464 4 0.044
regulation of cell motility GO:2000145 131 0.044
regulation of epithelial cell proliferation GO:0050678 49 0.044
inflammatory response GO:0006954 150 0.044
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.044
response to vitamin GO:0033273 131 0.044
Rat
neuron projection development GO:0031175 273 0.044
mechanoreceptor differentiation GO:0042490 2 0.044
cellular response to mechanical stimulus GO:0071260 48 0.044
positive regulation of cellular component movement GO:0051272 102 0.044
single organism biosynthetic process GO:0044711 342 0.043
Human
negative regulation of developmental growth GO:0048640 15 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.043
metanephric glomerulus morphogenesis GO:0072275 1 0.042
negative regulation of cellular biosynthetic process GO:0031327 161 0.042
positive regulation of neurogenesis GO:0050769 165 0.041
digestive system development GO:0055123 41 0.041
sexual reproduction GO:0019953 148 0.041
Mouse
response to vitamin d GO:0033280 34 0.041
Rat
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.040
Human
negative regulation of cell growth GO:0030308 33 0.040
regulation of mapk cascade GO:0043408 116 0.040
response to organophosphorus GO:0046683 102 0.040
cyclic purine nucleotide metabolic process GO:0052652 62 0.040
Human
response to dexamethasone GO:0071548 49 0.039
Rat
nucleoside catabolic process GO:0009164 126 0.039
response to lipopolysaccharide GO:0032496 191 0.039
cellular catabolic process GO:0044248 295 0.039
Human Rat
sensory organ development GO:0007423 74 0.039
cytosolic calcium ion homeostasis GO:0051480 140 0.039
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.039
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.039
Human
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 5 0.038
response to hexose GO:0009746 144 0.038
positive regulation of cytoskeleton organization GO:0051495 26 0.038
amine metabolic process GO:0009308 38 0.038
regulation of actin filament based process GO:0032970 42 0.038
response to camp GO:0051591 91 0.038
positive regulation of nervous system development GO:0051962 178 0.038
regulation of sodium ion transport GO:0002028 21 0.038
Mouse Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.038
Rat
negative regulation of biosynthetic process GO:0009890 168 0.037
cellular response to organic cyclic compound GO:0071407 202 0.037
camera type eye development GO:0043010 48 0.037
proteolysis GO:0006508 175 0.037
organonitrogen compound catabolic process GO:1901565 179 0.037
Human Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.037
Rat
positive regulation of transcription dna templated GO:0045893 197 0.037
regulation of cell projection organization GO:0031344 175 0.036
response to nicotine GO:0035094 51 0.036
Rat
cation transmembrane transport GO:0098655 263 0.036
Rat
macromolecular complex subunit organization GO:0043933 339 0.036
macromolecular complex assembly GO:0065003 273 0.036
negative regulation of gene expression GO:0010629 199 0.036
t helper 1 type immune response GO:0042088 1 0.036
response to tumor necrosis factor GO:0034612 56 0.036
cellular amine metabolic process GO:0044106 38 0.036
bone remodeling GO:0046849 23 0.036
cellular response to organonitrogen compound GO:0071417 197 0.036
response to bacterium GO:0009617 200 0.036
anterior posterior pattern specification GO:0009952 1 0.036
epithelium development GO:0060429 96 0.036
striated muscle contraction GO:0006941 44 0.035
single organism intracellular transport GO:1902582 166 0.035
reactive oxygen species metabolic process GO:0072593 37 0.035
mrna transcription from rna polymerase ii promoter GO:0042789 1 0.035
negative regulation of intracellular signal transduction GO:1902532 38 0.035
transcription dna templated GO:0006351 377 0.035
aminoglycan biosynthetic process GO:0006023 4 0.035
tube development GO:0035295 89 0.035
Mouse
regulation of metanephros development GO:0072215 4 0.035
negative regulation of blood vessel morphogenesis GO:2000181 10 0.035
regulation of ion transmembrane transport GO:0034765 121 0.035
Rat
regulation of organelle organization GO:0033043 80 0.035
response to ethanol GO:0045471 162 0.034
cell projection organization GO:0030030 302 0.034
response to acid chemical GO:0001101 222 0.034
metanephric s shaped body morphogenesis GO:0072284 2 0.034
regulation of cardiac muscle cell contraction GO:0086004 11 0.034
regulation of muscle system process GO:0090257 79 0.034
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.034
muscle cell differentiation GO:0042692 52 0.034
cell morphogenesis involved in differentiation GO:0000904 119 0.034
regulation of protein modification process GO:0031399 194 0.034
Rat
muscle organ development GO:0007517 50 0.034
cell migration involved in metanephros development GO:0035788 2 0.034
guanosine containing compound catabolic process GO:1901069 71 0.033
regulation of cellular component biogenesis GO:0044087 86 0.033
t cell activation GO:0042110 29 0.032
cardiac cell development GO:0055006 16 0.032
hair cell differentiation GO:0035315 2 0.032
positive regulation of intracellular signal transduction GO:1902533 138 0.032
cellular response to insulin stimulus GO:0032869 81 0.032
response to mineralocorticoid GO:0051385 49 0.032
negative regulation of epithelial cell proliferation GO:0050680 16 0.032
regulation of cell migration GO:0030334 128 0.032
gliogenesis GO:0042063 93 0.031
hematopoietic progenitor cell differentiation GO:0002244 2 0.031
response to other organism GO:0051707 220 0.031
regulation of neural precursor cell proliferation GO:2000177 16 0.031
nucleobase containing compound catabolic process GO:0034655 152 0.031
neuron development GO:0048666 286 0.031
chemosensory behavior GO:0007635 2 0.031
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.031
Human
gamete generation GO:0007276 124 0.031
Mouse
purine ribonucleotide catabolic process GO:0009154 136 0.031
protein complex biogenesis GO:0070271 263 0.031
multicellular organismal homeostasis GO:0048871 49 0.031
central nervous system development GO:0007417 311 0.030
angiogenesis GO:0001525 53 0.030
Mouse
purine ribonucleoside catabolic process GO:0046130 124 0.030
tissue morphogenesis GO:0048729 22 0.030
establishment of protein localization GO:0045184 141 0.030
muscle cell development GO:0055001 26 0.030
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.030
negative regulation of endothelial cell proliferation GO:0001937 5 0.030
camp biosynthetic process GO:0006171 47 0.030
ribonucleoside triphosphate metabolic process GO:0009199 141 0.030
regulation of vasoconstriction GO:0019229 44 0.030
Rat
positive regulation of kinase activity GO:0033674 77 0.030
carbohydrate derivative catabolic process GO:1901136 147 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
developmental process involved in reproduction GO:0003006 159 0.029
Mouse
protein localization to organelle GO:0033365 57 0.029
cellular component morphogenesis GO:0032989 155 0.029
regulation of stem cell differentiation GO:2000736 2 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
mesenchymal to epithelial transition GO:0060231 3 0.029
organic acid transport GO:0015849 116 0.029
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.029
regulation of ossification GO:0030278 32 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
negative regulation of protein phosphorylation GO:0001933 44 0.028
Rat
regulation of muscle organ development GO:0048634 26 0.028
kidney epithelium development GO:0072073 19 0.028
cytokine mediated signaling pathway GO:0019221 43 0.028
dna metabolic process GO:0006259 96 0.028
purine nucleoside catabolic process GO:0006152 124 0.028

Nos3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.122
Human
cardiovascular system disease DOID:1287 0 0.122
Human
vascular disease DOID:178 0 0.036
Human
urinary system disease DOID:18 0 0.029