Rattus norvegicus

66 known processes

Nr1d1

nuclear receptor subfamily 1, group D, member 1

(Aliases: REV-ERBAALPHA)

Nr1d1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of rna biosynthetic process GO:1902680 197 0.464
positive regulation of nucleic acid templated transcription GO:1903508 197 0.359
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.332
nucleic acid templated transcription GO:0097659 379 0.321
rna metabolic process GO:0016070 406 0.298
positive regulation of biosynthetic process GO:0009891 319 0.292
regulation of nucleic acid templated transcription GO:1903506 380 0.283
regulation of rna biosynthetic process GO:2001141 381 0.279
positive regulation of cellular biosynthetic process GO:0031328 295 0.278
rna biosynthetic process GO:0032774 380 0.264
positive regulation of gene expression GO:0010628 244 0.256
liver development GO:0001889 90 0.247
Rat
transcription dna templated GO:0006351 377 0.244
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.243
Human Zebrafish Rat
regulation of rna metabolic process GO:0051252 391 0.221
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.158
positive regulation of rna metabolic process GO:0051254 203 0.132
transcription from rna polymerase ii promoter GO:0006366 252 0.114
Human Zebrafish Rat
positive regulation of transcription dna templated GO:0045893 197 0.098
regulation of transcription dna templated GO:0006355 374 0.093
organic acid metabolic process GO:0006082 292 0.081
Mouse
response to peptide GO:1901652 292 0.072
negative regulation of transcription dna templated GO:0045892 116 0.070
Human Zebrafish Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.066
single organism biosynthetic process GO:0044711 342 0.059
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.057
Human Zebrafish Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.056
Human Zebrafish Mouse Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.053
Human Zebrafish Mouse Rat
regulation of multicellular organismal development GO:2000026 376 0.050
Rat Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.047
Human Zebrafish
oxoacid metabolic process GO:0043436 290 0.047
Mouse
lipid metabolic process GO:0006629 283 0.046
Mouse Rat Fly
negative regulation of biosynthetic process GO:0009890 168 0.046
Human Zebrafish Mouse Rat
cellular amino acid metabolic process GO:0006520 107 0.046
cell projection organization GO:0030030 302 0.045
muscle system process GO:0003012 115 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
Rat
cytokine production involved in inflammatory response GO:0002534 1 0.043
protein complex assembly GO:0006461 263 0.043
regulation of cellular component organization GO:0051128 368 0.042
cellular ketone metabolic process GO:0042180 51 0.042
Human Mouse Fly
intracellular signal transduction GO:0035556 314 0.042
Rat
rhythmic process GO:0048511 156 0.041
synaptic transmission GO:0007268 235 0.040
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
Human Zebrafish Mouse
cellular amine metabolic process GO:0044106 38 0.037
cation transmembrane transport GO:0098655 263 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.037
homeostatic process GO:0042592 331 0.036
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.036
Rat
protein phosphorylation GO:0006468 345 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.034
cellular response to nitrogen compound GO:1901699 210 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
Human Mouse Fly
transmembrane transport GO:0055085 412 0.033
catabolic process GO:0009056 351 0.033
Mouse
cellular component assembly GO:0022607 360 0.032
response to peptide hormone GO:0043434 278 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.031
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.031
macromolecular complex assembly GO:0065003 273 0.031
regulation of phosphorylation GO:0042325 248 0.031
Rat
amine metabolic process GO:0009308 38 0.030
regulation of signal transduction GO:0009966 318 0.030
Human Rat
regulation of protein modification process GO:0031399 194 0.030
entrainment of circadian clock GO:0009649 3 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
response to nutrient levels GO:0031667 370 0.028
Rat
regulation of nervous system development GO:0051960 264 0.028
Rat
negative regulation of gene expression GO:0010629 199 0.028
Human Zebrafish Mouse Rat
carboxylic acid transport GO:0046942 115 0.028
ion transmembrane transport GO:0034220 365 0.028
negative regulation of metabolic process GO:0009892 331 0.028
Human Zebrafish Mouse Rat
intracellular transport GO:0046907 185 0.027
organophosphate metabolic process GO:0019637 370 0.027
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.027
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
regulation of cell differentiation GO:0045595 320 0.027
Mouse Rat
reproductive process GO:0022414 372 0.026
Rat
cellular component biogenesis GO:0044085 368 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
organic substance catabolic process GO:1901575 316 0.026
Mouse
protein autophosphorylation GO:0046777 66 0.025
circadian regulation of gene expression GO:0032922 3 0.025
Mouse
regulation of protein metabolic process GO:0051246 289 0.025
Rat
growth GO:0040007 165 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
chemical homeostasis GO:0048878 292 0.025
Mouse
negative regulation of cell communication GO:0010648 158 0.024
Human
organic anion transport GO:0015711 132 0.024
regulation of homeostatic process GO:0032844 101 0.024
Mouse
protein complex subunit organization GO:0071822 302 0.023
programmed cell death GO:0012501 392 0.023
Rat
macromolecule localization GO:0033036 252 0.022
cell cell signaling GO:0007267 335 0.022
Mouse Rat
protein complex biogenesis GO:0070271 263 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
cellular catabolic process GO:0044248 295 0.022
Mouse
regulation of proteasomal protein catabolic process GO:0061136 4 0.022
nitrogen compound transport GO:0071705 229 0.022
Mouse
cellular lipid metabolic process GO:0044255 208 0.022
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
Rat
anatomical structure morphogenesis GO:0009653 298 0.021
response to inorganic substance GO:0010035 377 0.021
cation transport GO:0006812 382 0.021
cell cycle GO:0007049 101 0.021
metal ion transport GO:0030001 289 0.020
nucleotide metabolic process GO:0009117 279 0.020
central nervous system development GO:0007417 311 0.020
Rat
response to oxygen levels GO:0070482 265 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
Human Zebrafish Mouse
behavior GO:0007610 205 0.020
positive regulation of protein modification process GO:0031401 142 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
Rat
response to hexose GO:0009746 144 0.020
Mouse
negative regulation of rna metabolic process GO:0051253 123 0.019
Human Zebrafish Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
response to decreased oxygen levels GO:0036293 237 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.018
purine containing compound metabolic process GO:0072521 253 0.018
regulation of neuron differentiation GO:0045664 208 0.018
Rat
multi organism reproductive process GO:0044703 262 0.018
Rat
cellular homeostasis GO:0019725 252 0.018
Mouse
regulation of protein phosphorylation GO:0001932 183 0.018
locomotion GO:0040011 237 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
positive regulation of molecular function GO:0044093 230 0.018
neuron projection development GO:0031175 273 0.017
ras protein signal transduction GO:0007265 29 0.017
sodium ion transport GO:0006814 82 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
regulation of molecular function GO:0065009 398 0.017
Rat
nucleoside metabolic process GO:0009116 179 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
positive regulation of phosphorylation GO:0042327 177 0.016
Rat
monovalent inorganic cation transport GO:0015672 172 0.016
cellular component movement GO:0006928 248 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
aromatic compound catabolic process GO:0019439 168 0.016
regulation of cell proliferation GO:0042127 359 0.016
Mouse Rat
establishment of protein localization GO:0045184 141 0.016
blood circulation GO:0008015 183 0.016
response to insulin GO:0032868 133 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
protein transport GO:0015031 132 0.016
response to wounding GO:0009611 254 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
Human Zebrafish Mouse Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
regulation of cell growth GO:0001558 85 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
response to extracellular stimulus GO:0009991 380 0.015
Rat
negative regulation of response to stimulus GO:0048585 155 0.015
Human
regulation of synaptic plasticity GO:0048167 70 0.015
Rat
cell growth GO:0016049 104 0.015
protein heterooligomerization GO:0051291 89 0.015
positive regulation of developmental process GO:0051094 283 0.015
Rat
regulation of apoptotic process GO:0042981 335 0.015
Rat
negative regulation of innate immune response GO:0045824 4 0.015
protein oligomerization GO:0051259 191 0.015
action potential GO:0001508 54 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
spindle organization GO:0007051 2 0.015
axis specification GO:0009798 4 0.015
cellular protein localization GO:0034613 122 0.014
response to hypoxia GO:0001666 231 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
circulatory system process GO:0003013 183 0.014
organelle organization GO:0006996 266 0.014
regulation of cell development GO:0060284 263 0.014
Rat
protein localization to organelle GO:0033365 57 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of secretion by cell GO:1903530 208 0.014
Mouse
regulation of cell projection organization GO:0031344 175 0.014
carbohydrate metabolic process GO:0005975 130 0.014
Human Mouse
cytoplasmic transport GO:0016482 115 0.014
dendrite development GO:0016358 72 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
amino acid transport GO:0006865 70 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
peptidyl amino acid modification GO:0018193 126 0.013
response to biotic stimulus GO:0009607 226 0.013
Human Fly
oxidation reduction process GO:0055114 304 0.013
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.013
Human Mouse Rat
adult locomotory behavior GO:0008344 4 0.013
anion transport GO:0006820 178 0.013
cellular response to peptide GO:1901653 133 0.013
cellular ion homeostasis GO:0006873 184 0.013
regulation of catalytic activity GO:0050790 304 0.013
Rat
response to other organism GO:0051707 220 0.013
Human Fly
regulation of transmembrane transport GO:0034762 122 0.013
response to nutrient GO:0007584 248 0.013
Rat
ribonucleoside metabolic process GO:0009119 174 0.013
anterior posterior pattern specification GO:0009952 1 0.013
neuron development GO:0048666 286 0.013
monocarboxylic acid transport GO:0015718 52 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
response to metal ion GO:0010038 253 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
Rat
secretion by cell GO:0032940 248 0.013
Mouse
response to oxidative stress GO:0006979 186 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
localization of cell GO:0051674 202 0.013
ribonucleotide metabolic process GO:0009259 231 0.012
positive regulation of catabolic process GO:0009896 78 0.012
metal ion homeostasis GO:0055065 186 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
Mouse
positive regulation of response to stimulus GO:0048584 285 0.012
Human Rat
dna replication GO:0006260 37 0.012
regulation of catabolic process GO:0009894 113 0.012
negative regulation of nervous system development GO:0051961 79 0.012
muscle contraction GO:0006936 88 0.012
ion homeostasis GO:0050801 212 0.012
hormone transport GO:0009914 121 0.012
Mouse
regulation of ion transport GO:0043269 245 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
cellular response to stress GO:0033554 269 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
single organism catabolic process GO:0044712 283 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
response to reactive oxygen species GO:0000302 120 0.012
response to estrogen GO:0043627 232 0.012
Rat
regulation of anatomical structure size GO:0090066 135 0.012
organic acid transport GO:0015849 116 0.012
glycogen metabolic process GO:0005977 23 0.012
Mouse
cell cycle process GO:0022402 57 0.012
regulation of cell cycle GO:0051726 73 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
Human Mouse
cofactor metabolic process GO:0051186 95 0.012
secretion GO:0046903 307 0.012
Mouse
cellular response to cytokine stimulus GO:0071345 127 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
eye morphogenesis GO:0048592 4 0.011
amide transport GO:0042886 105 0.011
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
heterocycle catabolic process GO:0046700 167 0.011
organic hydroxy compound transport GO:0015850 77 0.011
p38mapk cascade GO:0038066 1 0.011
aging GO:0007568 241 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
heart process GO:0003015 57 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
protein localization GO:0008104 191 0.011
regulation of neurogenesis GO:0050767 247 0.011
Rat
protein homooligomerization GO:0051260 91 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
Human
chemosensory behavior GO:0007635 2 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
negative regulation of developmental process GO:0051093 125 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
response to toxic substance GO:0009636 133 0.011
mesoderm development GO:0007498 2 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
Human Zebrafish Mouse Rat
cation homeostasis GO:0055080 195 0.011
male mating behavior GO:0060179 3 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
cellular chemical homeostasis GO:0055082 247 0.011
Mouse
regulation of cellular localization GO:0060341 263 0.011
Mouse
single organism behavior GO:0044708 130 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
proteolysis GO:0006508 175 0.011
Mouse
lipid storage GO:0019915 1 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
purine containing compound biosynthetic process GO:0072522 85 0.010
chromosome segregation GO:0007059 2 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
negative regulation of stress activated mapk cascade GO:0032873 4 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
brain development GO:0007420 247 0.010
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
cardiac muscle cell contraction GO:0086003 10 0.010
embryonic pattern specification GO:0009880 1 0.010
neuron differentiation GO:0030182 368 0.010
Rat
regulation of intracellular signal transduction GO:1902531 218 0.010
Rat
purine ribonucleotide catabolic process GO:0009154 136 0.010
fatty acid metabolic process GO:0006631 99 0.010
learning or memory GO:0007611 90 0.010
regulation of cell cycle process GO:0010564 31 0.010
regulation of muscle system process GO:0090257 79 0.010

Nr1d1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
musculoskeletal system disease DOID:17 0 0.015
muscular disease DOID:0080000 0 0.015
myopathy DOID:423 0 0.015
muscle tissue disease DOID:66 0 0.015
central nervous system disease DOID:331 0 0.011