Rattus norvegicus

0 known processes

Nr1i3

nuclear receptor subfamily 1, group I, member 3

(Aliases: CAR,MGC108525)

Nr1i3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid transport GO:0046942 115 0.183
oxoacid metabolic process GO:0043436 290 0.173
Rat
cellular response to hormone stimulus GO:0032870 247 0.171
Zebrafish Rat
drug transmembrane transport GO:0006855 13 0.148
rhythmic process GO:0048511 156 0.142
single organism reproductive process GO:0044702 297 0.130
Rat
immune system process GO:0002376 204 0.128
carboxylic acid metabolic process GO:0019752 289 0.128
Rat
monocarboxylic acid transport GO:0015718 52 0.121
anion transport GO:0006820 178 0.112
organic anion transport GO:0015711 132 0.110
response to hypoxia GO:0001666 231 0.108
Rat
cellular response to oxygen containing compound GO:1901701 386 0.098
Rat
organic acid transport GO:0015849 116 0.081
regeneration GO:0031099 163 0.078
Rat
cellular response to nitrogen compound GO:1901699 210 0.075
response to vitamin GO:0033273 131 0.071
Rat
positive regulation of signaling GO:0023056 270 0.069
Rat
reproductive process GO:0022414 372 0.068
Rat
macromolecule localization GO:0033036 252 0.067
response to biotic stimulus GO:0009607 226 0.066
Rat
response to inorganic substance GO:0010035 377 0.065
Rat
response to estradiol GO:0032355 164 0.064
Rat
amino acid transport GO:0006865 70 0.064
cellular component assembly GO:0022607 360 0.064
cation transport GO:0006812 382 0.064
Rat
regulation of blood pressure GO:0008217 83 0.062
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.061
Mouse Rat
multi organism reproductive process GO:0044703 262 0.058
Rat
response to acid chemical GO:0001101 222 0.058
Rat
cellular response to stress GO:0033554 269 0.056
Rat
behavioral response to nicotine GO:0035095 2 0.056
Rat
response to bacterium GO:0009617 200 0.056
Rat
organic acid metabolic process GO:0006082 292 0.056
Rat
multicellular organism reproduction GO:0032504 233 0.056
Rat
transmembrane transport GO:0055085 412 0.056
antibiotic transport GO:0042891 2 0.055
response to decreased oxygen levels GO:0036293 237 0.055
Rat
response to estrogen GO:0043627 232 0.055
Rat
cellular response to external stimulus GO:0071496 118 0.055
Rat
drug catabolic process GO:0042737 1 0.054
cell motility GO:0048870 202 0.053
Rat
immune response GO:0006955 104 0.052
cellular response to peptide GO:1901653 133 0.052
cellular amino acid metabolic process GO:0006520 107 0.051
transcription dna templated GO:0006351 377 0.051
Human Zebrafish Mouse Rat
response to nutrient GO:0007584 248 0.050
Rat
macromolecular complex assembly GO:0065003 273 0.049
drug transport GO:0015893 18 0.049
catecholamine transport GO:0051937 37 0.048
reproduction GO:0000003 245 0.048
Rat
sensory perception GO:0007600 101 0.048
regulation of cell proliferation GO:0042127 359 0.047
Rat
defense response GO:0006952 194 0.046
Rat
oxidation reduction process GO:0055114 304 0.046
Rat Fly
response to peptide GO:1901652 292 0.046
Rat
localization of cell GO:0051674 202 0.046
Rat
response to oxidative stress GO:0006979 186 0.045
cellular hormone metabolic process GO:0034754 49 0.045
lipid metabolic process GO:0006629 283 0.045
Rat
regulation of blood vessel size GO:0050880 89 0.044
Rat
locomotion GO:0040011 237 0.044
Rat
circulatory system process GO:0003013 183 0.043
Rat
isoprenoid metabolic process GO:0006720 45 0.042
Rat
response to toxic substance GO:0009636 133 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.042
Mouse Rat
negative regulation of rna metabolic process GO:0051253 123 0.041
Mouse Rat
negative regulation of biosynthetic process GO:0009890 168 0.041
Mouse Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.040
Mouse Rat
regulation of hormone levels GO:0010817 187 0.040
Rat
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
Rat
regulation of immune system process GO:0002682 123 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.039
Rat
response to extracellular stimulus GO:0009991 380 0.039
Rat Fly
organic hydroxy compound metabolic process GO:1901615 115 0.039
Rat
intracellular signal transduction GO:0035556 314 0.039
response to lipopolysaccharide GO:0032496 191 0.039
Rat
programmed cell death GO:0012501 392 0.038
Rat
cellular ketone metabolic process GO:0042180 51 0.037
Rat
regulation of molecular function GO:0065009 398 0.037
Rat
hormone metabolic process GO:0042445 69 0.037
cellular response to organic cyclic compound GO:0071407 202 0.037
Zebrafish Rat
neurological system process GO:0050877 219 0.037
cellular response to organonitrogen compound GO:0071417 197 0.037
negative regulation of collagen biosynthetic process GO:0032966 4 0.037
Rat
response to mechanical stimulus GO:0009612 134 0.036
Rat
modified amino acid transport GO:0072337 12 0.036
amide transport GO:0042886 105 0.036
Rat
homeostatic process GO:0042592 331 0.036
Fly
blood circulation GO:0008015 183 0.036
Rat
protein complex assembly GO:0006461 263 0.036
single organism catabolic process GO:0044712 283 0.035
organic substance catabolic process GO:1901575 316 0.035
dna metabolic process GO:0006259 96 0.035
Rat
lipid localization GO:0010876 62 0.035
rna metabolic process GO:0016070 406 0.034
Human Zebrafish Mouse Rat
negative regulation of signaling GO:0023057 157 0.033
response to peptide hormone GO:0043434 278 0.033
Rat
apoptotic process GO:0006915 381 0.032
Rat
regulation of cell motility GO:2000145 131 0.031
Rat
regulation of rna biosynthetic process GO:2001141 381 0.031
Human Zebrafish Mouse Rat
tissue development GO:0009888 252 0.031
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
Mouse Rat
regulation of locomotion GO:0040012 148 0.031
Rat
multicellular organismal reproductive process GO:0048609 233 0.031
Rat
cell migration GO:0016477 197 0.031
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
Human Rat
terpenoid metabolic process GO:0006721 37 0.030
Rat
negative regulation of molecular function GO:0044092 133 0.030
Rat
alpha amino acid metabolic process GO:1901605 71 0.030
cellular response to insulin stimulus GO:0032869 81 0.029
cellular response to peptide hormone stimulus GO:0071375 120 0.029
liver development GO:0001889 90 0.029
negative regulation of transcription dna templated GO:0045892 116 0.029
Mouse Rat
cation homeostasis GO:0055080 195 0.029
single organism biosynthetic process GO:0044711 342 0.028
Rat
regulation of apoptotic process GO:0042981 335 0.028
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.028
response to vitamin a GO:0033189 36 0.028
Rat
coenzyme metabolic process GO:0006732 86 0.028
multi multicellular organism process GO:0044706 138 0.028
Rat
response to retinoic acid GO:0032526 63 0.028
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.027
Zebrafish Rat
protein oligomerization GO:0051259 191 0.027
response to purine containing compound GO:0014074 126 0.027
Rat
cellular catabolic process GO:0044248 295 0.027
response to external biotic stimulus GO:0043207 221 0.027
Rat
response to molecule of bacterial origin GO:0002237 194 0.027
Rat
metal ion transport GO:0030001 289 0.027
Rat
protein complex biogenesis GO:0070271 263 0.027
digestive tract development GO:0048565 39 0.026
Rat
response to xenobiotic stimulus GO:0009410 23 0.026
amine metabolic process GO:0009308 38 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
Human Rat
oligopeptide transport GO:0006857 4 0.026
female pregnancy GO:0007565 122 0.026
Rat
vitamin transport GO:0051180 14 0.026
muscle contraction GO:0006936 88 0.026
regulation of cellular component organization GO:0051128 368 0.026
Rat
regulation of renal sodium excretion GO:0035813 20 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.025
Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
response to alkaloid GO:0043279 132 0.025
Rat
response to insulin GO:0032868 133 0.025
Rat
lipid oxidation GO:0034440 30 0.025
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.024
response to molecule of fungal origin GO:0002238 3 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.023
cellular component biogenesis GO:0044085 368 0.023
cellular response to abiotic stimulus GO:0071214 85 0.023
gland development GO:0048732 155 0.023
metal ion homeostasis GO:0055065 186 0.023
nucleic acid templated transcription GO:0097659 379 0.023
Human Zebrafish Mouse Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
Human Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
Mouse Rat
regulation of programmed cell death GO:0043067 341 0.022
Rat
regulation of cell development GO:0060284 263 0.022
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.022
Human Zebrafish Mouse Rat
response to ionizing radiation GO:0010212 59 0.022
positive regulation of transport GO:0051050 245 0.022
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
Human Zebrafish Rat
catabolic process GO:0009056 351 0.022
cellular response to lipid GO:0071396 201 0.022
Zebrafish Rat
neuropeptide signaling pathway GO:0007218 29 0.022
regulation of telomerase activity GO:0051972 2 0.021
Rat
organophosphate metabolic process GO:0019637 370 0.021
Rat
reproductive system development GO:0061458 128 0.021
Rat
response to increased oxygen levels GO:0036296 45 0.021
Rat
cellular chemical homeostasis GO:0055082 247 0.021
muscle cell proliferation GO:0033002 84 0.021
Rat
regulation of cell migration GO:0030334 128 0.021
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
Mouse Rat
inorganic ion transmembrane transport GO:0098660 229 0.021
ion homeostasis GO:0050801 212 0.021
glucan metabolic process GO:0044042 23 0.021
Fly
signal release GO:0023061 145 0.021
Rat
growth GO:0040007 165 0.021
Rat
response to glucocorticoid GO:0051384 223 0.021
gamete generation GO:0007276 124 0.020
response to camp GO:0051591 91 0.020
negative regulation of metabolic process GO:0009892 331 0.020
Mouse Rat
positive regulation of immune system process GO:0002684 90 0.020
positive regulation of gene expression GO:0010628 244 0.020
Human Rat
cellular lipid metabolic process GO:0044255 208 0.020
Rat
macromolecular complex subunit organization GO:0043933 339 0.020
response to oxygen levels GO:0070482 265 0.020
Rat
response to corticosteroid GO:0031960 235 0.020
establishment of protein localization GO:0045184 141 0.020
positive regulation of cell communication GO:0010647 271 0.020
Rat
response to vitamin d GO:0033280 34 0.020
Rat
response to ethanol GO:0045471 162 0.020
cellular response to ketone GO:1901655 51 0.020
Rat
protein complex subunit organization GO:0071822 302 0.020
response to starvation GO:0042594 59 0.019
Rat Fly
organ regeneration GO:0031100 101 0.019
Rat
positive regulation of secretion GO:0051047 140 0.019
Rat
head development GO:0060322 247 0.019
regulation of organelle organization GO:0033043 80 0.019
cellular amine metabolic process GO:0044106 38 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
Rat
developmental process involved in reproduction GO:0003006 159 0.018
Rat
cellular response to xenobiotic stimulus GO:0071466 19 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
Rat
lipid storage GO:0019915 1 0.018
sodium ion transport GO:0006814 82 0.017
positive regulation of signal transduction GO:0009967 175 0.017
spermatogenesis GO:0007283 99 0.017
sodium independent organic anion transport GO:0043252 2 0.017
glutathione transport GO:0034635 2 0.017
circadian rhythm GO:0007623 88 0.017
cellular component movement GO:0006928 248 0.017
Rat
regulation of anatomical structure size GO:0090066 135 0.017
Rat
hepaticobiliary system development GO:0061008 90 0.017
vitamin a metabolic process GO:0006776 2 0.016
Rat
axis specification GO:0009798 4 0.016
regulation of nervous system development GO:0051960 264 0.016
Rat
regulation of secretion GO:0051046 224 0.016
Rat
development of primary sexual characteristics GO:0045137 107 0.016
cellular response to fluid shear stress GO:0071498 4 0.016
regulation of membrane potential GO:0042391 110 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
Rat
positive regulation of cellular component movement GO:0051272 102 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
dicarboxylic acid transport GO:0006835 34 0.016
choline transport GO:0015871 4 0.016
peptidyl amino acid modification GO:0018193 126 0.016
cholesterol homeostasis GO:0042632 3 0.016
Fly
diterpenoid metabolic process GO:0016101 33 0.016
Rat
cellular response to corticosteroid stimulus GO:0071384 69 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
Rat
positive regulation of biosynthetic process GO:0009891 319 0.015
Human Rat
positive regulation of cellular component organization GO:0051130 200 0.015
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
gastrulation GO:0007369 2 0.015
response to other organism GO:0051707 220 0.015
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.015
Human Rat
regulation of kinase activity GO:0043549 117 0.015
nucleotide metabolic process GO:0009117 279 0.015
cellular macromolecule localization GO:0070727 122 0.015
renal sodium excretion GO:0035812 20 0.015
regulation of protein kinase activity GO:0045859 105 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
Rat
negative regulation of apoptotic process GO:0043066 181 0.015
Rat
dopamine transport GO:0015872 18 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
Rat
cellular response to alcohol GO:0097306 87 0.015
Rat
positive regulation of cell death GO:0010942 184 0.015
Rat
response to nicotine GO:0035094 51 0.015
Rat
lipid transport GO:0006869 61 0.014
sexual reproduction GO:0019953 148 0.014
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.014
vascular process in circulatory system GO:0003018 96 0.014
Rat
rna biosynthetic process GO:0032774 380 0.014
Human Zebrafish Mouse Rat
organic cyclic compound catabolic process GO:1901361 175 0.014
negative regulation of gene expression GO:0010629 199 0.014
Mouse Rat
organic acid biosynthetic process GO:0016053 83 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
single organism behavior GO:0044708 130 0.014
Rat
regulation of activation of jak2 kinase activity GO:0010534 1 0.014
cellular response to oxidative stress GO:0034599 76 0.014
regulation of transferase activity GO:0051338 123 0.014
Rat
regulation of secretion by cell GO:1903530 208 0.014
Rat
positive regulation of rna metabolic process GO:0051254 203 0.014
Human Rat
cellular response to oxygen levels GO:0071453 60 0.013
Rat
cofactor metabolic process GO:0051186 95 0.013
response to osmotic stress GO:0006970 42 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
Human Rat
regulation of system process GO:0044057 208 0.013
Rat
ribonucleotide biosynthetic process GO:0009260 85 0.013
calcitriol biosynthetic process from calciol GO:0036378 2 0.013
central nervous system development GO:0007417 311 0.013
Rat
exogenous drug catabolic process GO:0042738 1 0.013
intracellular transport GO:0046907 185 0.013
response to metal ion GO:0010038 253 0.013
Rat
regulation of tube size GO:0035150 89 0.013
Rat
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.013
Rat
cellular modified amino acid metabolic process GO:0006575 61 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
positive regulation of nervous system development GO:0051962 178 0.013
Rat
heterocycle catabolic process GO:0046700 167 0.013
protein tetramerization GO:0051262 38 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
neuron differentiation GO:0030182 368 0.013
synaptic transmission GO:0007268 235 0.013
response to cadmium ion GO:0046686 35 0.013
sex differentiation GO:0007548 113 0.013
response to carbohydrate GO:0009743 183 0.013
Rat
regulation of protein transport GO:0051223 68 0.013
regulation of intracellular protein transport GO:0033157 34 0.012
activation of jak2 kinase activity GO:0042977 2 0.012
steroid metabolic process GO:0008202 73 0.012
Rat
feeding behavior GO:0007631 53 0.012
protein transport GO:0015031 132 0.012
response to cytokine GO:0034097 215 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
aromatic compound catabolic process GO:0019439 168 0.012
anion transmembrane transport GO:0098656 77 0.012
response to nutrient levels GO:0031667 370 0.012
Rat Fly
chemical homeostasis GO:0048878 292 0.012
Fly
positive regulation of intracellular signal transduction GO:1902533 138 0.012
response to insecticide GO:0017085 21 0.012
cellular ion homeostasis GO:0006873 184 0.012
regulation of transcription dna templated GO:0006355 374 0.012
Human Zebrafish Mouse Rat
nitrogen compound transport GO:0071705 229 0.012
Rat
brain development GO:0007420 247 0.012
regulation of activation of janus kinase activity GO:0010533 1 0.012
intracellular protein transport GO:0006886 79 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
ras protein signal transduction GO:0007265 29 0.012
neuron projection development GO:0031175 273 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
Mouse Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
Human Rat
response to ketone GO:1901654 182 0.012
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.012
hormone secretion GO:0046879 115 0.012
Rat
copulation GO:0007620 17 0.012
neuron development GO:0048666 286 0.012
naphthalene containing compound metabolic process GO:0090420 2 0.012
response to activity GO:0014823 73 0.012
Rat
cellular cation homeostasis GO:0030003 180 0.012
negative regulation of transport GO:0051051 136 0.012
calcium ion homeostasis GO:0055074 162 0.011
proteolysis GO:0006508 175 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
regulation of ion transport GO:0043269 245 0.011
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.011
Rat
ribose phosphate metabolic process GO:0019693 235 0.011
multicellular organism growth GO:0035264 1 0.011
cellular homeostasis GO:0019725 252 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
Mouse Rat
negative regulation of programmed cell death GO:0043069 183 0.011
Rat
regulation of systemic arterial blood pressure GO:0003073 30 0.011
cell growth GO:0016049 104 0.011
Rat
hormone transport GO:0009914 121 0.011
Rat
positive regulation of neuron differentiation GO:0045666 126 0.011
negative regulation of cell communication GO:0010648 158 0.011
biphenyl catabolic process GO:0070980 2 0.011
transmission of nerve impulse GO:0019226 42 0.011
intestinal absorption GO:0050892 3 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of cell growth GO:0001558 85 0.011
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.011
Human Rat
muscle system process GO:0003012 115 0.011
male gamete generation GO:0048232 99 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
Fly
glycosyl compound metabolic process GO:1901657 182 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
locomotor rhythm GO:0045475 1 0.011
angiotensin mediated drinking behavior GO:0003051 2 0.011
regulation of protein localization GO:0032880 81 0.011
secretion GO:0046903 307 0.011
Rat
regulation of lipid metabolic process GO:0019216 68 0.011
Rat
response to cocaine GO:0042220 39 0.011
secretion by cell GO:0032940 248 0.010
Rat
protein phosphorylation GO:0006468 345 0.010
monoamine transport GO:0015844 43 0.010
organelle organization GO:0006996 266 0.010
regulation of organic acid transport GO:0032890 35 0.010
protein homotetramerization GO:0051289 25 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
inner ear morphogenesis GO:0042472 1 0.010
action potential GO:0001508 54 0.010
negative regulation of telomerase activity GO:0051974 1 0.010
Rat
nucleoside metabolic process GO:0009116 179 0.010
carbohydrate metabolic process GO:0005975 130 0.010
Rat Fly
regulation of neuron projection development GO:0010975 161 0.010

Nr1i3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.033
inherited metabolic disorder DOID:655 0 0.033
disease of anatomical entity DOID:7 0 0.016
endocrine system disease DOID:28 0 0.016