Rattus norvegicus

0 known processes

Nr4a1

nuclear receptor subfamily 4, group A, member 1

(Aliases: Nur77,Ngfi-b,HMR)

Nr4a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.982
positive regulation of neuron apoptotic process GO:0043525 33 0.960
inactivation of mapk activity GO:0000188 2 0.954
regulation of rna biosynthetic process GO:2001141 381 0.933
Human Mouse
rna metabolic process GO:0016070 406 0.906
Human Mouse
regulation of neuron apoptotic process GO:0043523 83 0.887
regulation of nucleic acid templated transcription GO:1903506 380 0.883
Human Mouse
cellular response to mycophenolic acid GO:0071506 2 0.879
neuron apoptotic process GO:0051402 88 0.874
nucleic acid templated transcription GO:0097659 379 0.873
Human Mouse
rna biosynthetic process GO:0032774 380 0.860
Human Mouse
long term synaptic potentiation GO:0060291 21 0.838
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.823
Human Mouse
response to mycophenolic acid GO:0071505 2 0.811
negative regulation of neuron apoptotic process GO:0043524 45 0.791
regulation of rna metabolic process GO:0051252 391 0.778
Human Mouse
response to amphetamine GO:0001975 25 0.772
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.763
collateral sprouting GO:0048668 2 0.756
response to camp GO:0051591 91 0.748
conditioned taste aversion GO:0001661 2 0.740
glomerular mesangial cell proliferation GO:0072110 4 0.714
embryonic skeletal system morphogenesis GO:0048704 3 0.711
regulation of apoptotic process GO:0042981 335 0.666
Mouse
positive regulation of metanephros development GO:0072216 2 0.657
skeletal muscle cell differentiation GO:0035914 2 0.649
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.646
Human Mouse
transcription dna templated GO:0006351 377 0.644
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.640
Human Mouse
cell type specific apoptotic process GO:0097285 134 0.638
transcription from rna polymerase ii promoter GO:0006366 252 0.622
Human Mouse
response to purine containing compound GO:0014074 126 0.617
response to peptide hormone GO:0043434 278 0.617
Rat
response to amine GO:0014075 46 0.603
positive regulation of rna metabolic process GO:0051254 203 0.597
Human Mouse
positive regulation of cell proliferation involved in kidney development GO:1901724 4 0.577
response to peptide GO:1901652 292 0.552
Rat
response to catecholamine GO:0071869 16 0.551
negative regulation of apoptotic process GO:0043066 181 0.547
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.534
regulation of transcription dna templated GO:0006355 374 0.516
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.508
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.475
Human Mouse
positive regulation of glomerulus development GO:0090193 4 0.464
cell projection morphogenesis GO:0048858 123 0.452
positive regulation of g0 to g1 transition GO:0070318 2 0.446
response to organophosphorus GO:0046683 102 0.445
negative regulation of programmed cell death GO:0043069 183 0.445
Mouse
glomerular mesangium development GO:0072109 4 0.444
cell proliferation involved in kidney development GO:0072111 5 0.438
apoptotic process GO:0006915 381 0.412
Mouse
bmp signaling pathway GO:0030509 4 0.407
negative regulation of cell death GO:0060548 229 0.403
Mouse
response to follicle stimulating hormone GO:0032354 18 0.403
response to toxic substance GO:0009636 133 0.400
Rat
neuron death GO:0070997 127 0.395
positive regulation of cellular biosynthetic process GO:0031328 295 0.388
Human Mouse
positive regulation of transcription dna templated GO:0045893 197 0.386
Human Mouse
axonogenesis GO:0007409 71 0.366
protein sumoylation GO:0016925 4 0.347
neuron projection morphogenesis GO:0048812 122 0.347
negative regulation of nervous system development GO:0051961 79 0.346
cellular response to insulin stimulus GO:0032869 81 0.346
negative regulation of rna metabolic process GO:0051253 123 0.345
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.337
Human Mouse
positive regulation of gene expression GO:0010628 244 0.332
Human Mouse
regulation of glomerulus development GO:0090192 4 0.331
response to hydrogen peroxide GO:0042542 89 0.320
endocytosis GO:0006897 84 0.317
Fly
cell proliferation involved in metanephros development GO:0072203 2 0.310
axon guidance GO:0007411 24 0.310
central nervous system neuron axonogenesis GO:0021955 1 0.307
neuron projection guidance GO:0097485 24 0.305
programmed cell death GO:0012501 392 0.287
Mouse
interleukin 1 mediated signaling pathway GO:0070498 2 0.279
response to mechanical stimulus GO:0009612 134 0.277
tissue development GO:0009888 252 0.275
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.273
Human Mouse
mrna 3 end processing GO:0031124 1 0.263
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.261
response to insecticide GO:0017085 21 0.253
Rat
cellular response to camp GO:0071320 26 0.251
metanephric nephron development GO:0072210 7 0.249
cellular response to gonadotropin stimulus GO:0071371 17 0.246
negative regulation of neuron death GO:1901215 69 0.244
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.240
enzyme linked receptor protein signaling pathway GO:0007167 116 0.239
regulation of system process GO:0044057 208 0.239
response to light stimulus GO:0009416 52 0.238
neurological system process GO:0050877 219 0.237
cellular response to organic cyclic compound GO:0071407 202 0.234
regulation of neuron death GO:1901214 115 0.228
parasympathetic nervous system development GO:0048486 1 0.228
positive regulation of biosynthetic process GO:0009891 319 0.227
Human Mouse
response to inorganic substance GO:0010035 377 0.226
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.226
neuromuscular process GO:0050905 2 0.224
regulation of programmed cell death GO:0043067 341 0.217
Mouse
cell morphogenesis involved in differentiation GO:0000904 119 0.215
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 1 0.208
response to metal ion GO:0010038 253 0.205
response to extracellular stimulus GO:0009991 380 0.205
circadian behavior GO:0048512 24 0.204
positive regulation of apoptotic process GO:0043065 154 0.199
Mouse
positive regulation of glomerular mesangial cell proliferation GO:0072126 4 0.199
motor neuron axon guidance GO:0008045 1 0.198
central nervous system development GO:0007417 311 0.198
forebrain neuron development GO:0021884 3 0.195
response to oxidative stress GO:0006979 186 0.195
positive regulation of programmed cell death GO:0043068 157 0.192
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.191
regulation of metanephros development GO:0072215 4 0.187
cellular response to stress GO:0033554 269 0.184
negative regulation of metabolic process GO:0009892 331 0.181
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.180
negative regulation of macromolecule metabolic process GO:0010605 260 0.179
Mouse
cellular component morphogenesis GO:0032989 155 0.178
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 11 0.175
response to heparin GO:0071503 2 0.173
regulation of glomerular mesangial cell proliferation GO:0072124 4 0.172
reproduction GO:0000003 245 0.171
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.171
behavior GO:0007610 205 0.166
positive regulation of glomerular metanephric mesangial cell proliferation GO:0072303 1 0.164
negative regulation of mapk cascade GO:0043409 20 0.164
cellular response to isoquinoline alkaloid GO:0071317 6 0.163
response to oxygen levels GO:0070482 265 0.157
negative regulation of wnt signaling pathway GO:0030178 7 0.154
neuron differentiation GO:0030182 368 0.153
response to corticosteroid GO:0031960 235 0.153
regulation of kidney development GO:0090183 15 0.152
response to insulin GO:0032868 133 0.150
carbohydrate derivative metabolic process GO:1901135 346 0.148
positive regulation of metanephric glomerulus development GO:0072300 1 0.147
heart process GO:0003015 57 0.146
cellular response to mechanical stimulus GO:0071260 48 0.144
embryonic cranial skeleton morphogenesis GO:0048701 2 0.143
cellular response to hormone stimulus GO:0032870 247 0.142
cell morphogenesis GO:0000902 142 0.142
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.141
sensory organ development GO:0007423 74 0.141
response to increased oxygen levels GO:0036296 45 0.138
response to decreased oxygen levels GO:0036293 237 0.136
mesoderm development GO:0007498 2 0.135
regulation of protein kinase activity GO:0045859 105 0.132
single organism behavior GO:0044708 130 0.131
response to growth factor GO:0070848 189 0.128
Human
connective tissue development GO:0061448 33 0.127
cellular response to peptide GO:1901653 133 0.126
glomerulus development GO:0032835 10 0.121
cellular response to endogenous stimulus GO:0071495 377 0.119
Human
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.118
t cell differentiation GO:0030217 9 0.118
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.117
axon development GO:0061564 96 0.117
brain development GO:0007420 247 0.116
anatomical structure morphogenesis GO:0009653 298 0.115
Human
regulation of synaptic transmission GO:0050804 141 0.114
cellular response to oxygen containing compound GO:1901701 386 0.114
negative regulation of nucleic acid templated transcription GO:1903507 117 0.112
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.111
regulation of cellular protein metabolic process GO:0032268 267 0.111
Mouse
response to glucocorticoid GO:0051384 223 0.110
mesoderm formation GO:0001707 1 0.109
multi multicellular organism process GO:0044706 138 0.108
response to monoamine GO:0071867 17 0.108
metanephric glomerulus development GO:0072224 3 0.107
cell part morphogenesis GO:0032990 123 0.106
regulation of nervous system development GO:0051960 264 0.106
phagocytosis GO:0006909 17 0.105
Fly
cellular response to external stimulus GO:0071496 118 0.104
rhombomere morphogenesis GO:0021593 1 0.104
regulation of respiratory gaseous exchange GO:0043576 2 0.103
negative regulation of transcription dna templated GO:0045892 116 0.102
positive regulation of developmental process GO:0051094 283 0.102
cell cell signaling GO:0007267 335 0.102
neuron projection development GO:0031175 273 0.100
positive regulation of osteoclast differentiation GO:0045672 5 0.096
regulation of neurogenesis GO:0050767 247 0.096
positive regulation of neuron death GO:1901216 43 0.095
positive regulation of cell death GO:0010942 184 0.095
Mouse
vesicle mediated transport GO:0016192 181 0.094
Fly
response to reactive oxygen species GO:0000302 120 0.094
neuron development GO:0048666 286 0.092
response to isoquinoline alkaloid GO:0014072 28 0.092
response to hypoxia GO:0001666 231 0.090
negative regulation of oligodendrocyte differentiation GO:0048715 3 0.089
response to carbon monoxide GO:0034465 4 0.087
metal ion transport GO:0030001 289 0.086
response to ethanol GO:0045471 162 0.085
multi organism reproductive process GO:0044703 262 0.085
glial cell differentiation GO:0010001 65 0.084
negative regulation of gene expression GO:0010629 199 0.083
Mouse
response to ammonium ion GO:0060359 71 0.081
negative regulation of rna biosynthetic process GO:1902679 118 0.080
reproductive process GO:0022414 372 0.080
response to carbohydrate GO:0009743 183 0.078
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.078
regulation of multicellular organismal development GO:2000026 376 0.076
Fly
wound healing GO:0042060 122 0.076
gastrulation GO:0007369 2 0.076
cellular response to lipid GO:0071396 201 0.074
cellular response to abiotic stimulus GO:0071214 85 0.072
positive regulation of cell proliferation GO:0008284 249 0.072
Human
response to radiation GO:0009314 137 0.071
hindbrain morphogenesis GO:0021575 2 0.071
aging GO:0007568 241 0.071
regulation of neuronal synaptic plasticity GO:0048168 31 0.071
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.070
response to calcium ion GO:0051592 59 0.070
striated muscle tissue development GO:0014706 58 0.069
Mouse
vasculature development GO:0001944 70 0.069
Human
protein dephosphorylation GO:0006470 38 0.069
single organism biosynthetic process GO:0044711 342 0.069
rhythmic process GO:0048511 156 0.068
renal system development GO:0072001 67 0.068
response to ketone GO:1901654 182 0.068
regulation of molecular function GO:0065009 398 0.067
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.067
Mouse
locomotion GO:0040011 237 0.066
Human
gliogenesis GO:0042063 93 0.066
response to cold GO:0009409 29 0.066
regulation of synaptic plasticity GO:0048167 70 0.065
negative regulation of signal transduction GO:0009968 83 0.064
regulation of protein metabolic process GO:0051246 289 0.063
Mouse
cellular response to fluid shear stress GO:0071498 4 0.063
angiogenesis GO:0001525 53 0.063
Human
metanephric glomerulus vasculature development GO:0072239 1 0.062
regulation of bmp signaling pathway GO:0030510 2 0.062
oligodendrocyte differentiation GO:0048709 32 0.060
muscle structure development GO:0061061 87 0.060
Mouse
cytokine mediated signaling pathway GO:0019221 43 0.059
photoperiodism GO:0009648 4 0.059
response to acid chemical GO:0001101 222 0.058
response to cytokine GO:0034097 215 0.058
response to norepinephrine GO:0071873 5 0.058
tube development GO:0035295 89 0.057
response to monosaccharide GO:0034284 159 0.057
negative regulation of multicellular organismal process GO:0051241 203 0.056
regulation of cellular amine metabolic process GO:0033238 8 0.056
negative regulation of kinase activity GO:0033673 27 0.055
synaptic growth at neuromuscular junction GO:0051124 1 0.054
developmental growth GO:0048589 100 0.053
response to external biotic stimulus GO:0043207 221 0.053
positive regulation of mrna catabolic process GO:0061014 2 0.053
metanephros development GO:0001656 14 0.053
positive regulation of multicellular organismal process GO:0051240 387 0.053
negative regulation of cellular protein metabolic process GO:0032269 106 0.052
Mouse
cellular response to growth factor stimulus GO:0071363 162 0.052
Human
rhythmic behavior GO:0007622 24 0.052
nephron development GO:0072006 22 0.051
response to nutrient levels GO:0031667 370 0.051
cellular response to cycloheximide GO:0071409 4 0.050
chemotaxis GO:0006935 66 0.049
Human
taxis GO:0042330 67 0.048
Human
negative regulation of cell communication GO:0010648 158 0.048
adult locomotory behavior GO:0008344 4 0.047
cell projection organization GO:0030030 302 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
negative regulation of signaling GO:0023057 157 0.046
hippocampus development GO:0021766 30 0.045
regulation of cellular component movement GO:0051270 150 0.044
response to corticosterone GO:0051412 40 0.044
regulation of protein serine threonine kinase activity GO:0071900 64 0.044
response to alkaloid GO:0043279 132 0.043
limbic system development GO:0021761 38 0.043
positive regulation of synaptic transmission GO:0050806 62 0.043
embryonic skeletal system development GO:0048706 3 0.043
mesoderm morphogenesis GO:0048332 1 0.042
regulation of canonical wnt signaling pathway GO:0060828 4 0.042
regulation of cell cycle GO:0051726 73 0.042
cognition GO:0050890 92 0.041
negative regulation of transferase activity GO:0051348 29 0.041
eye development GO:0001654 50 0.041
entrainment of circadian clock GO:0009649 3 0.040
embryo development GO:0009790 49 0.039
organic substance catabolic process GO:1901575 316 0.039
female pregnancy GO:0007565 122 0.039
developmental growth involved in morphogenesis GO:0060560 33 0.038
telencephalon development GO:0021537 62 0.038
cell cycle g2 m phase transition GO:0044839 6 0.038
positive regulation of myeloid leukocyte differentiation GO:0002763 7 0.038
regulation of cell proliferation involved in kidney development GO:1901722 4 0.037
rhombomere development GO:0021546 1 0.037
cellular component movement GO:0006928 248 0.037
Human
forebrain development GO:0030900 98 0.037
growth GO:0040007 165 0.036
multicellular organism reproduction GO:0032504 233 0.036
negative regulation of phosphorus metabolic process GO:0010563 80 0.036
formation of primary germ layer GO:0001704 1 0.035
nucleobase containing compound catabolic process GO:0034655 152 0.035
adult behavior GO:0030534 16 0.035
kidney vasculature development GO:0061440 6 0.035
response to cocaine GO:0042220 39 0.035
response to glucose GO:0009749 136 0.035
negative regulation of phosphate metabolic process GO:0045936 80 0.034
synaptic transmission GO:0007268 235 0.034
positive regulation of mrna metabolic process GO:1903313 4 0.033
cellular response to oxidative stress GO:0034599 76 0.033
response to hyperoxia GO:0055093 45 0.033
glomerulus vasculature development GO:0072012 6 0.033
cellular ketone metabolic process GO:0042180 51 0.033
regulation of transferase activity GO:0051338 123 0.033
single organism reproductive process GO:0044702 297 0.033
response to testosterone GO:0033574 55 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
forebrain generation of neurons GO:0021872 8 0.032
circadian regulation of gene expression GO:0032922 3 0.032
cellular component assembly GO:0022607 360 0.032
cellular response to cytokine stimulus GO:0071345 127 0.032
pallium development GO:0021543 42 0.031
embryonic organ morphogenesis GO:0048562 5 0.031
cellular response to steroid hormone stimulus GO:0071383 93 0.031
circulatory system process GO:0003013 183 0.031
forebrain neuron differentiation GO:0021879 7 0.031
metanephric glomerular mesangium development GO:0072223 1 0.031
regulation of vasculature development GO:1901342 44 0.030
regulation of cellular catabolic process GO:0031329 101 0.030
organ regeneration GO:0031100 101 0.030
Rat
skeletal system development GO:0001501 41 0.030
response to gonadotropin GO:0034698 34 0.030
regulation of protein modification process GO:0031399 194 0.029
regulation of mrna 3 end processing GO:0031440 1 0.029
negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 1 0.029
negative regulation of molecular function GO:0044092 133 0.029
Mouse
response to interleukin 1 GO:0070555 55 0.029
regulation of heart contraction GO:0008016 48 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
facial nerve development GO:0021561 1 0.028
heterocycle catabolic process GO:0046700 167 0.028
blood circulation GO:0008015 183 0.028
circulatory system development GO:0072359 134 0.028
Human
cellular response to organonitrogen compound GO:0071417 197 0.027
lipid biosynthetic process GO:0008610 128 0.027
catabolic process GO:0009056 351 0.027
muscle system process GO:0003012 115 0.027
anatomical structure formation involved in morphogenesis GO:0048646 83 0.026
Human
regulation of catalytic activity GO:0050790 304 0.026
Mouse
regulation of cell differentiation GO:0045595 320 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
positive regulation of cellular catabolic process GO:0031331 71 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
regulation of cell proliferation GO:0042127 359 0.025
Human
immune system development GO:0002520 41 0.025
sexual reproduction GO:0019953 148 0.025
cellular homeostasis GO:0019725 252 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.025
semicircular canal development GO:0060872 1 0.025
cellular component biogenesis GO:0044085 368 0.024
chromosome segregation GO:0007059 2 0.024
muscle tissue development GO:0060537 58 0.024
Mouse
organic acid metabolic process GO:0006082 292 0.023
d amino acid transport GO:0042940 1 0.023
regulation of catabolic process GO:0009894 113 0.023
positive regulation of myeloid cell differentiation GO:0045639 7 0.023
head development GO:0060322 247 0.023
t cell activation GO:0042110 29 0.023
ossification GO:0001503 70 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
Mouse
protein phosphorylation GO:0006468 345 0.022
cellular macromolecule catabolic process GO:0044265 29 0.022
cellular response to drug GO:0035690 30 0.022
rna catabolic process GO:0006401 3 0.022
divalent inorganic cation transport GO:0072511 134 0.022
divalent metal ion transport GO:0070838 132 0.022
single organism intracellular transport GO:1902582 166 0.022
mrna stabilization GO:0048255 2 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
muscle contraction GO:0006936 88 0.021
cellular response to hypoxia GO:0071456 51 0.021
regulation of mapk cascade GO:0043408 116 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 24 0.021
response to gamma radiation GO:0010332 24 0.021
autonomic nervous system development GO:0048483 3 0.021
anion transport GO:0006820 178 0.020
cation transport GO:0006812 382 0.020
muscle organ development GO:0007517 50 0.020
Mouse
regulation of erk1 and erk2 cascade GO:0070372 41 0.020
positive regulation of mrna processing GO:0050685 2 0.020
heart contraction GO:0060047 57 0.020
cellular response to nitrogen compound GO:1901699 210 0.019
regulation of cardiac muscle contraction GO:0055117 17 0.019
transmission of nerve impulse GO:0019226 42 0.019
organic anion transport GO:0015711 132 0.019
regulation of ion transport GO:0043269 245 0.019
negative regulation of protein kinase activity GO:0006469 23 0.019
chemical homeostasis GO:0048878 292 0.019
cellular response to metal ion GO:0071248 55 0.019
regulation of dopamine metabolic process GO:0042053 5 0.018
collagen metabolic process GO:0032963 21 0.018
regulation of blood vessel endothelial cell migration GO:0043535 4 0.018
regulation of tube size GO:0035150 89 0.018
kidney development GO:0001822 67 0.018
regulation of dna metabolic process GO:0051052 60 0.018
gamete generation GO:0007276 124 0.018
regulation of signal transduction GO:0009966 318 0.018
multicellular organism growth GO:0035264 1 0.017
regeneration GO:0031099 163 0.017
Rat
regulation of muscle system process GO:0090257 79 0.017
renal system vasculature development GO:0061437 6 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
nerve development GO:0021675 11 0.017
cardiac muscle contraction GO:0060048 27 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of blood vessel size GO:0050880 89 0.017
response to transforming growth factor beta GO:0071559 46 0.016
cellular response to reactive oxygen species GO:0034614 55 0.016
inner ear morphogenesis GO:0042472 1 0.016
purine containing compound metabolic process GO:0072521 253 0.016
cellular catabolic process GO:0044248 295 0.016
response to hexose GO:0009746 144 0.016
dephosphorylation GO:0016311 98 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
negative regulation of phosphorylation GO:0042326 57 0.016
response to axon injury GO:0048678 59 0.016
cellular amine metabolic process GO:0044106 38 0.016
cell growth GO:0016049 104 0.016
negative regulation of protein modification process GO:0031400 52 0.016
response to estradiol GO:0032355 164 0.016
cellular amino acid metabolic process GO:0006520 107 0.015
calcium ion transport GO:0006816 131 0.015
mapk cascade GO:0000165 140 0.015
axis specification GO:0009798 4 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
positive regulation of protein modification process GO:0031401 142 0.015
positive regulation of catabolic process GO:0009896 78 0.015
cellular response to alkaloid GO:0071312 25 0.015
developmental process involved in reproduction GO:0003006 159 0.015
dna metabolic process GO:0006259 96 0.015
axon regeneration GO:0031103 28 0.015
carbohydrate metabolic process GO:0005975 130 0.015
negative regulation of cysteine type endopeptidase activity GO:2000117 18 0.015
Mouse
organ senescence GO:0010260 2 0.014
digestive system development GO:0055123 41 0.014
growth plate cartilage development GO:0003417 2 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
digestive tract morphogenesis GO:0048546 8 0.014
organ morphogenesis GO:0009887 75 0.013
protein complex assembly GO:0006461 263 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
Mouse
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
immune system process GO:0002376 204 0.013
amine metabolic process GO:0009308 38 0.013
response to estrogen GO:0043627 232 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
erk1 and erk2 cascade GO:0070371 48 0.013
localization of cell GO:0051674 202 0.013
Human
regulation of phosphorus metabolic process GO:0051174 349 0.013
negative regulation of developmental process GO:0051093 125 0.013
positive regulation of transport GO:0051050 245 0.013
leukocyte activation GO:0045321 76 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of cell adhesion GO:0030155 52 0.013
negative regulation of nf kappab transcription factor activity GO:0032088 4 0.013
sensory perception GO:0007600 101 0.013
oxoacid metabolic process GO:0043436 290 0.013
positive regulation of cardiac muscle contraction GO:0060452 4 0.012
intracellular signal transduction GO:0035556 314 0.012
positive regulation of immune system process GO:0002684 90 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
response to electrical stimulus GO:0051602 56 0.012
cellular response to interleukin 1 GO:0071347 37 0.012
mitotic spindle organization GO:0007052 2 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of transcription factor import into nucleus GO:0042993 4 0.012
regulation of p38mapk cascade GO:1900744 1 0.012
male gamete generation GO:0048232 99 0.012
secretion GO:0046903 307 0.012
spindle organization GO:0007051 2 0.012
embryonic pattern specification GO:0009880 1 0.012
ion transmembrane transport GO:0034220 365 0.012
axon ensheathment GO:0008366 40 0.012
response to nutrient GO:0007584 248 0.012
regulation of translation GO:0006417 27 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
membrane hyperpolarization GO:0060081 11 0.011
potassium ion transport GO:0006813 97 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
response to anoxia GO:0034059 4 0.011
cation homeostasis GO:0055080 195 0.011
regulation of ossification GO:0030278 32 0.011

Nr4a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.062
disease of anatomical entity DOID:7 0 0.062
nervous system disease DOID:863 0 0.062
neuropathy DOID:870 0 0.062
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020
charcot marie tooth disease DOID:10595 0 0.015
disease of metabolism DOID:0014667 0 0.012