Rattus norvegicus

40 known processes

Nrg1

neuregulin 1

Nrg1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.680
Human Zebrafish Mouse
response to lipopolysaccharide GO:0032496 191 0.672
negative regulation of multicellular organismal process GO:0051241 203 0.661
cation transport GO:0006812 382 0.601
anion transport GO:0006820 178 0.584
regulation of tube size GO:0035150 89 0.530
regulation of cell proliferation GO:0042127 359 0.526
Human
positive regulation of cell communication GO:0010647 271 0.522
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.484
rhythmic process GO:0048511 156 0.462
protein phosphorylation GO:0006468 345 0.455
Human Mouse Rat
regulation of secretion GO:0051046 224 0.452
Human
regulation of system process GO:0044057 208 0.414
response to estradiol GO:0032355 164 0.414
cation transmembrane transport GO:0098655 263 0.409
regulation of phosphorylation GO:0042325 248 0.400
Human Mouse
regulation of blood vessel size GO:0050880 89 0.391
monocarboxylic acid transport GO:0015718 52 0.382
oxoacid metabolic process GO:0043436 290 0.350
positive regulation of signal transduction GO:0009967 175 0.349
Mouse
regulation of cellular component organization GO:0051128 368 0.349
Human
regulation of programmed cell death GO:0043067 341 0.348
Human
positive regulation of signaling GO:0023056 270 0.346
Mouse
negative regulation of cell death GO:0060548 229 0.343
Human
organic acid metabolic process GO:0006082 292 0.343
cellular response to endogenous stimulus GO:0071495 377 0.340
programmed cell death GO:0012501 392 0.336
Human
neuron development GO:0048666 286 0.335
regulation of blood circulation GO:1903522 110 0.332
mapk cascade GO:0000165 140 0.330
Mouse
sensory perception GO:0007600 101 0.322
cell cell signaling GO:0007267 335 0.317
Mouse
neurological system process GO:0050877 219 0.313
response to inorganic substance GO:0010035 377 0.306
secretion by cell GO:0032940 248 0.303
neuron differentiation GO:0030182 368 0.302
Zebrafish Mouse
homeostatic process GO:0042592 331 0.300
regulation of phosphate metabolic process GO:0019220 349 0.292
Human Mouse
wound healing GO:0042060 122 0.292
Human Zebrafish
cell migration GO:0016477 197 0.287
Zebrafish Mouse
neuron projection development GO:0031175 273 0.280
renal filtration GO:0097205 10 0.278
hormone transport GO:0009914 121 0.272
cellular response to lipid GO:0071396 201 0.266
localization of cell GO:0051674 202 0.259
Zebrafish Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.259
Human Mouse
organic acid transport GO:0015849 116 0.258
negative regulation of biosynthetic process GO:0009890 168 0.255
Human
negative regulation of cell proliferation GO:0008285 119 0.253
regulation of nucleic acid templated transcription GO:1903506 380 0.250
Human
neuron projection morphogenesis GO:0048812 122 0.249
carboxylic acid metabolic process GO:0019752 289 0.243
single organism biosynthetic process GO:0044711 342 0.239
positive regulation of phosphate metabolic process GO:0045937 262 0.234
Human Mouse
regulation of transcription dna templated GO:0006355 374 0.232
Human
organic anion transport GO:0015711 132 0.232
brain development GO:0007420 247 0.232
Zebrafish
response to mechanical stimulus GO:0009612 134 0.231
regulation of apoptotic process GO:0042981 335 0.224
Human
muscle cell proliferation GO:0033002 84 0.217
Human
regulation of signal transduction GO:0009966 318 0.213
Human Mouse
developmental process involved in reproduction GO:0003006 159 0.212
cellular response to organic cyclic compound GO:0071407 202 0.208
carboxylic acid transport GO:0046942 115 0.206
regulation of protein metabolic process GO:0051246 289 0.202
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.201
neuropeptide signaling pathway GO:0007218 29 0.200
cell part morphogenesis GO:0032990 123 0.192
cellular response to organonitrogen compound GO:0071417 197 0.189
regulation of cellular ketone metabolic process GO:0010565 27 0.188
monocarboxylic acid metabolic process GO:0032787 152 0.187
negative regulation of developmental process GO:0051093 125 0.186
nitrogen compound transport GO:0071705 229 0.184
response to molecule of bacterial origin GO:0002237 194 0.184
positive regulation of multicellular organismal process GO:0051240 387 0.180
Human Mouse
regulation of cellular localization GO:0060341 263 0.177
regulation of cellular amino acid metabolic process GO:0006521 2 0.177
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.177
regulation of rna biosynthetic process GO:2001141 381 0.177
Human
cellular component movement GO:0006928 248 0.174
Zebrafish Mouse
rna metabolic process GO:0016070 406 0.173
Human
cellular response to cytokine stimulus GO:0071345 127 0.172
positive regulation of intracellular signal transduction GO:1902533 138 0.171
Mouse
response to corticosteroid GO:0031960 235 0.167
reproductive system development GO:0061458 128 0.165
regulation of protein phosphorylation GO:0001932 183 0.163
Human Mouse
gonad development GO:0008406 104 0.161
regulation of response to stress GO:0080134 126 0.160
positive regulation of cellular protein metabolic process GO:0032270 167 0.159
Human Mouse
transmembrane transport GO:0055085 412 0.158
phasic smooth muscle contraction GO:0014821 3 0.157
vascular process in circulatory system GO:0003018 96 0.157
response to hypoxia GO:0001666 231 0.156
lipid biosynthetic process GO:0008610 128 0.156
rna biosynthetic process GO:0032774 380 0.156
Human
positive regulation of catalytic activity GO:0043085 184 0.154
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 260 0.154
Human Mouse
renal system process GO:0003014 40 0.154
response to peptide GO:1901652 292 0.153
regulation of multicellular organismal development GO:2000026 376 0.153
Human Mouse
behavior GO:0007610 205 0.151
Mouse
cellular amino acid metabolic process GO:0006520 107 0.151
chemical homeostasis GO:0048878 292 0.150
response to bacterium GO:0009617 200 0.146
regulation of catalytic activity GO:0050790 304 0.145
Human Mouse
cell projection organization GO:0030030 302 0.143
regulation of cellular protein metabolic process GO:0032268 267 0.143
Human Mouse
regulation of hormone levels GO:0010817 187 0.143
locomotion GO:0040011 237 0.143
Zebrafish Mouse
apoptotic process GO:0006915 381 0.143
Human
regeneration GO:0031099 163 0.140
Zebrafish
nucleic acid templated transcription GO:0097659 379 0.137
Human
tissue development GO:0009888 252 0.137
Human Zebrafish Mouse
ion transmembrane transport GO:0034220 365 0.137
positive regulation of rna biosynthetic process GO:1902680 197 0.136
regulation of transferase activity GO:0051338 123 0.134
Human Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.134
organ morphogenesis GO:0009887 75 0.131
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.131
regulation of cell differentiation GO:0045595 320 0.130
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.129
Human
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.128
circadian rhythm GO:0007623 88 0.128
heart morphogenesis GO:0003007 3 0.128
Human
head development GO:0060322 247 0.127
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 252 0.126
cellular ketone metabolic process GO:0042180 51 0.126
cell morphogenesis GO:0000902 142 0.125
Mouse
metal ion transport GO:0030001 289 0.125
positive regulation of secretion by cell GO:1903532 128 0.123
single organism reproductive process GO:0044702 297 0.123
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.123
learning or memory GO:0007611 90 0.120
response to reactive oxygen species GO:0000302 120 0.119
regulation of anatomical structure size GO:0090066 135 0.119
positive regulation of cell projection organization GO:0031346 111 0.118
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.118
Human
alpha amino acid metabolic process GO:1901605 71 0.115
somatostatin receptor signaling pathway GO:0038169 4 0.115
response to alkaloid GO:0043279 132 0.115
gland development GO:0048732 155 0.115
positive regulation of response to stimulus GO:0048584 285 0.115
Mouse
glomerular filtration GO:0003094 10 0.115
cellular response to nitrogen compound GO:1901699 210 0.114
macromolecular complex subunit organization GO:0043933 339 0.113
Human
signal release GO:0023061 145 0.112
reproductive process GO:0022414 372 0.111
response to cytokine GO:0034097 215 0.111
regulation of cell projection organization GO:0031344 175 0.111
regulation of cellular amine metabolic process GO:0033238 8 0.109
epithelium development GO:0060429 96 0.109
Human
positive regulation of protein kinase activity GO:0045860 73 0.109
Human Mouse
sex differentiation GO:0007548 113 0.108
axon development GO:0061564 96 0.108
amino acid transport GO:0006865 70 0.107
vasoconstriction GO:0042310 54 0.107
response to wounding GO:0009611 254 0.106
Human Zebrafish
synaptic transmission GO:0007268 235 0.105
Mouse
amine metabolic process GO:0009308 38 0.104
regulation of nervous system development GO:0051960 264 0.104
response to other organism GO:0051707 220 0.104
carbohydrate derivative metabolic process GO:1901135 346 0.102
response to nicotine GO:0035094 51 0.102
regulation of molecular function GO:0065009 398 0.101
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.101
Human
response to external biotic stimulus GO:0043207 221 0.100
monovalent inorganic cation transport GO:0015672 172 0.100
divalent inorganic cation transport GO:0072511 134 0.099
acid secretion GO:0046717 48 0.097
heart contraction GO:0060047 57 0.096
cellular component morphogenesis GO:0032989 155 0.096
Mouse
regulation of rna metabolic process GO:0051252 391 0.095
Human
sensory perception of pain GO:0019233 73 0.094
regulation of neurogenesis GO:0050767 247 0.094
negative regulation of programmed cell death GO:0043069 183 0.094
Human
cellular amine metabolic process GO:0044106 38 0.093
negative regulation of signal transduction GO:0009968 83 0.093
Human
organonitrogen compound biosynthetic process GO:1901566 167 0.092
organophosphate metabolic process GO:0019637 370 0.091
negative regulation of cellular metabolic process GO:0031324 281 0.090
Human
cellular response to tumor necrosis factor GO:0071356 46 0.090
cell motility GO:0048870 202 0.089
Zebrafish Mouse
positive regulation of kinase activity GO:0033674 77 0.089
Human Mouse
regulation of neuron projection development GO:0010975 161 0.089
cellular component assembly GO:0022607 360 0.089
Human Mouse
steroid metabolic process GO:0008202 73 0.088
negative regulation of gene expression GO:0010629 199 0.087
Human
development of primary sexual characteristics GO:0045137 107 0.087
reproductive structure development GO:0048608 128 0.086
nucleoside phosphate metabolic process GO:0006753 283 0.086
response to temperature stimulus GO:0009266 94 0.085
positive regulation of biosynthetic process GO:0009891 319 0.084
negative regulation of response to stimulus GO:0048585 155 0.084
Human
peptidyl tyrosine phosphorylation GO:0018108 72 0.084
Human Rat
regulation of protein modification process GO:0031399 194 0.083
Human Mouse
response to heat GO:0009408 60 0.083
positive regulation of blood circulation GO:1903524 65 0.082
regulation of body fluid levels GO:0050878 90 0.082
response to tumor necrosis factor GO:0034612 56 0.082
hormone secretion GO:0046879 115 0.082
positive regulation of neuron projection development GO:0010976 99 0.082
negative regulation of metabolic process GO:0009892 331 0.081
Human Mouse
response to glucocorticoid GO:0051384 223 0.081
positive regulation of phosphorylation GO:0042327 177 0.081
Human Mouse
aging GO:0007568 241 0.080
positive regulation of cell differentiation GO:0045597 217 0.080
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.079
response to decreased oxygen levels GO:0036293 237 0.079
artery smooth muscle contraction GO:0014824 4 0.079
regulation of cell migration GO:0030334 128 0.079
positive regulation of cell death GO:0010942 184 0.078
regulation of blood pressure GO:0008217 83 0.078
female gonad development GO:0008585 53 0.076
apoptotic signaling pathway GO:0097190 27 0.076
Human
regulation of mapk cascade GO:0043408 116 0.076
response to estrogen GO:0043627 232 0.076
response to corticosterone GO:0051412 40 0.075
positive regulation of cellular biosynthetic process GO:0031328 295 0.075
regulation of kinase activity GO:0043549 117 0.075
Human Mouse
positive regulation of transport GO:0051050 245 0.075
response to ethanol GO:0045471 162 0.075
lipid transport GO:0006869 61 0.075
cellular response to hormone stimulus GO:0032870 247 0.074
regulation of cell growth GO:0001558 85 0.074
Human
negative regulation of apoptotic process GO:0043066 181 0.074
Human
response to ketone GO:1901654 182 0.073
transcription dna templated GO:0006351 377 0.072
Human
response to peptide hormone GO:0043434 278 0.072
positive regulation of protein metabolic process GO:0051247 178 0.071
Human Mouse
signal transduction by phosphorylation GO:0023014 144 0.071
Mouse
regulation of cell motility GO:2000145 131 0.071
cellular calcium ion homeostasis GO:0006874 160 0.071
positive regulation of apoptotic process GO:0043065 154 0.071
steroid biosynthetic process GO:0006694 48 0.071
response to hydrogen peroxide GO:0042542 89 0.071
regulation of protein kinase activity GO:0045859 105 0.069
Human Mouse
axonogenesis GO:0007409 71 0.069
positive regulation of cellular component organization GO:0051130 200 0.069
positive regulation of phosphorus metabolic process GO:0010562 262 0.068
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.067
intracellular signal transduction GO:0035556 314 0.067
Mouse
regulation of synaptic transmission gabaergic GO:0032228 17 0.067
positive regulation of hormone secretion GO:0046887 65 0.066
inflammatory response GO:0006954 150 0.066
nucleotide metabolic process GO:0009117 279 0.065
protein complex subunit organization GO:0071822 302 0.065
Human
protein complex assembly GO:0006461 263 0.065
Human
positive regulation of cell development GO:0010720 176 0.065
appendage morphogenesis GO:0035107 4 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.064
Human Rat
positive regulation of developmental process GO:0051094 283 0.064
Human Mouse
cellular response to stress GO:0033554 269 0.063
positive regulation of programmed cell death GO:0043068 157 0.063
organic acid biosynthetic process GO:0016053 83 0.062
neuron neuron synaptic transmission GO:0007270 60 0.062
negative regulation of osteoblast differentiation GO:0045668 2 0.061
cyclic nucleotide biosynthetic process GO:0009190 63 0.061
positive regulation of cellular amine metabolic process GO:0033240 3 0.060
regulation of membrane potential GO:0042391 110 0.060
sensory organ development GO:0007423 74 0.059
positive regulation of rna metabolic process GO:0051254 203 0.059
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.059
response to extracellular stimulus GO:0009991 380 0.059
embryonic appendage morphogenesis GO:0035113 4 0.058
development of primary female sexual characteristics GO:0046545 56 0.058
response to nutrient levels GO:0031667 370 0.057
positive regulation of cell migration GO:0030335 96 0.057
response to metal ion GO:0010038 253 0.057
smooth muscle cell proliferation GO:0048659 77 0.056
regulation of cell development GO:0060284 263 0.056
response to insulin GO:0032868 133 0.055
circulatory system process GO:0003013 183 0.055
erk1 and erk2 cascade GO:0070371 48 0.055
regulation of synaptic transmission GO:0050804 141 0.055
peptidyl amino acid modification GO:0018193 126 0.055
Human Rat
regulation of glomerular filtration GO:0003093 9 0.054
organophosphate biosynthetic process GO:0090407 143 0.053
central nervous system development GO:0007417 311 0.053
Zebrafish
cellular response to lipopolysaccharide GO:0071222 55 0.053
divalent inorganic cation homeostasis GO:0072507 165 0.052
forebrain development GO:0030900 98 0.052
macromolecular complex assembly GO:0065003 273 0.051
Human
response to transition metal nanoparticle GO:1990267 122 0.051
cellular response to growth factor stimulus GO:0071363 162 0.050
negative regulation of ossification GO:0030279 9 0.050
nucleoside phosphate biosynthetic process GO:1901293 102 0.050
response to electrical stimulus GO:0051602 56 0.050
ribonucleotide metabolic process GO:0009259 231 0.050
regulation of heart growth GO:0060420 12 0.049
Human
organ regeneration GO:0031100 101 0.049
multi multicellular organism process GO:0044706 138 0.049
cellular cation homeostasis GO:0030003 180 0.049
cellular response to steroid hormone stimulus GO:0071383 93 0.049
cell projection morphogenesis GO:0048858 123 0.049
multicellular organism reproduction GO:0032504 233 0.049
regulation of smooth muscle cell proliferation GO:0048660 75 0.049
ribose phosphate biosynthetic process GO:0046390 87 0.048
response to hexose GO:0009746 144 0.048
single organism behavior GO:0044708 130 0.048
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.048
ovulation cycle process GO:0022602 50 0.047
ribose phosphate metabolic process GO:0019693 235 0.047
purine nucleotide biosynthetic process GO:0006164 83 0.046
organic hydroxy compound metabolic process GO:1901615 115 0.045
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.045
Human
calcium ion transport GO:0006816 131 0.045
vesicle mediated transport GO:0016192 181 0.045
cognition GO:0050890 92 0.045
regulation of neuron differentiation GO:0045664 208 0.044
cellular homeostasis GO:0019725 252 0.044
muscle system process GO:0003012 115 0.044
positive regulation of nucleic acid templated transcription GO:1903508 197 0.044
response to oxygen levels GO:0070482 265 0.044
regulation of intracellular signal transduction GO:1902531 218 0.044
Mouse
response to purine containing compound GO:0014074 126 0.044
macromolecule localization GO:0033036 252 0.044
hepaticobiliary system development GO:0061008 90 0.044
regulation of metal ion transport GO:0010959 118 0.043
negative regulation of nervous system development GO:0051961 79 0.043
response to growth factor GO:0070848 189 0.043
response to acid chemical GO:0001101 222 0.043
circulatory system development GO:0072359 134 0.043
Human Mouse
ion homeostasis GO:0050801 212 0.043
hormone mediated signaling pathway GO:0009755 23 0.042
cell morphogenesis involved in differentiation GO:0000904 119 0.042
gastrulation GO:0007369 2 0.042
female sex differentiation GO:0046660 59 0.042
regulation of cellular component movement GO:0051270 150 0.042
positive regulation of transcription dna templated GO:0045893 197 0.042
multicellular organismal reproductive process GO:0048609 233 0.042
purine nucleotide metabolic process GO:0006163 229 0.041
amide transport GO:0042886 105 0.041
nucleotide biosynthetic process GO:0009165 98 0.041
formation of primary germ layer GO:0001704 1 0.040
regulation of locomotion GO:0040012 148 0.040
cation homeostasis GO:0055080 195 0.039
limb morphogenesis GO:0035108 4 0.039
ribonucleotide biosynthetic process GO:0009260 85 0.039
negative regulation of phosphate metabolic process GO:0045936 80 0.039
regulation of hormone secretion GO:0046883 106 0.039
blood vessel development GO:0001568 69 0.039
cellular chemical homeostasis GO:0055082 247 0.039
positive regulation of protein modification process GO:0031401 142 0.039
Human Mouse
cyclic purine nucleotide metabolic process GO:0052652 62 0.038
multi organism reproductive process GO:0044703 262 0.038
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.038
cellular response to glucocorticoid stimulus GO:0071385 68 0.038
positive regulation of secretion GO:0051047 140 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.038
Human
positive regulation of protein phosphorylation GO:0001934 135 0.038
Human Mouse
small molecule biosynthetic process GO:0044283 124 0.037
regulation of ion transport GO:0043269 245 0.037
regulation of lipid metabolic process GO:0019216 68 0.037
kidney development GO:0001822 67 0.037
positive regulation of molecular function GO:0044093 230 0.037
Human Mouse
embryo development GO:0009790 49 0.037
positive regulation of neurogenesis GO:0050769 165 0.037
angiogenesis GO:0001525 53 0.037
heart process GO:0003015 57 0.037
response to oxidative stress GO:0006979 186 0.037
carbohydrate homeostasis GO:0033500 75 0.037
protein complex biogenesis GO:0070271 263 0.037
Human
peptide hormone secretion GO:0030072 84 0.036
response to glucose GO:0009749 136 0.036
regulation of vasoconstriction GO:0019229 44 0.036
regulation of organelle organization GO:0033043 80 0.036
positive regulation of gene expression GO:0010628 244 0.036
regulation of purine nucleotide metabolic process GO:1900542 115 0.036
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.036
lymphocyte activation GO:0046649 43 0.036
regulation of secretion by cell GO:1903530 208 0.036
regulation of ras protein signal transduction GO:0046578 45 0.035
Mouse
memory GO:0007613 54 0.035
single organism catabolic process GO:0044712 283 0.035
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.035
regulation of amino acid transport GO:0051955 25 0.035
cellular amino acid biosynthetic process GO:0008652 32 0.035
negative regulation of nucleic acid templated transcription GO:1903507 117 0.034
Human
cellular response to alkaloid GO:0071312 25 0.034
liver development GO:0001889 90 0.034
male sex differentiation GO:0046661 64 0.034
protein homooligomerization GO:0051260 91 0.034
cellular lipid metabolic process GO:0044255 208 0.034
negative regulation of phosphorus metabolic process GO:0010563 80 0.034
response to mineralocorticoid GO:0051385 49 0.034
fatty acid metabolic process GO:0006631 99 0.033
positive regulation of mapk cascade GO:0043410 92 0.033
negative regulation of cellular protein metabolic process GO:0032269 106 0.033
neurotransmitter uptake GO:0001504 3 0.033
organic hydroxy compound biosynthetic process GO:1901617 51 0.033
chemotaxis GO:0006935 66 0.033
secretion GO:0046903 307 0.033
Human
response to dexamethasone GO:0071548 49 0.032
olfactory bulb interneuron differentiation GO:0021889 1 0.032
cellular ion homeostasis GO:0006873 184 0.032
vasodilation GO:0042311 44 0.032
regulation of lipid biosynthetic process GO:0046890 38 0.032
response to amine GO:0014075 46 0.032
ovulation cycle GO:0042698 67 0.032
negative regulation of cell development GO:0010721 82 0.032
regulation of nucleotide metabolic process GO:0006140 117 0.032
purine ribonucleotide biosynthetic process GO:0009152 81 0.032
detection of stimulus GO:0051606 24 0.031
lipid metabolic process GO:0006629 283 0.031
cellular response to abiotic stimulus GO:0071214 85 0.031
response to monosaccharide GO:0034284 159 0.030
regulation of muscle tissue development GO:1901861 25 0.030
Human Mouse
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.030
cellular catabolic process GO:0044248 295 0.030
peptide secretion GO:0002790 86 0.030
response to testosterone GO:0033574 55 0.030
regulation of erk1 and erk2 cascade GO:0070372 41 0.030
divalent metal ion transport GO:0070838 132 0.029
blood circulation GO:0008015 183 0.029
regulation of peptide hormone secretion GO:0090276 80 0.029
regulation of hydrolase activity GO:0051336 143 0.029
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.029
regulation of leukocyte activation GO:0002694 45 0.029
cell communication by chemical coupling GO:0010643 2 0.029
regulation of cellular component biogenesis GO:0044087 86 0.029
cyclic nucleotide metabolic process GO:0009187 80 0.029
purine containing compound biosynthetic process GO:0072522 85 0.029
neural crest cell migration GO:0001755 1 0.029
Zebrafish
glial cell differentiation GO:0010001 65 0.028
Zebrafish Mouse
negative regulation of neurogenesis GO:0050768 78 0.028
negative regulation of molecular function GO:0044092 133 0.028
inorganic cation transmembrane transport GO:0098662 202 0.028
negative regulation of rna biosynthetic process GO:1902679 118 0.028
Human
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.028
cell growth GO:0016049 104 0.028
Human
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
negative regulation of transport GO:0051051 136 0.027
Human
regulation of systemic arterial blood pressure GO:0003073 30 0.027
positive regulation of nucleotide metabolic process GO:0045981 91 0.027
response to carbohydrate GO:0009743 183 0.027
olfactory behavior GO:0042048 2 0.027
positive regulation of nervous system development GO:0051962 178 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.027
organonitrogen compound catabolic process GO:1901565 179 0.027
cellular response to peptide GO:1901653 133 0.027
ras protein signal transduction GO:0007265 29 0.026
Mouse
epithelial cell proliferation GO:0050673 54 0.026
positive regulation of long term synaptic potentiation GO:1900273 4 0.026
positive regulation of synaptic transmission gabaergic GO:0032230 9 0.026
carboxylic acid biosynthetic process GO:0046394 83 0.026
female pregnancy GO:0007565 122 0.026
positive regulation of neuron differentiation GO:0045666 126 0.026
protein oligomerization GO:0051259 191 0.026
hormone metabolic process GO:0042445 69 0.026
negative regulation of synaptic transmission gabaergic GO:0032229 6 0.026
epiboly involved in wound healing GO:0090505 2 0.026
glucose homeostasis GO:0042593 75 0.025
defense response GO:0006952 194 0.025
positive regulation of immune system process GO:0002684 90 0.025
negative regulation of growth GO:0045926 37 0.025
negative regulation of cell communication GO:0010648 158 0.025
Human
regulation of homeostatic process GO:0032844 101 0.025
urinary bladder smooth muscle contraction GO:0014832 4 0.025
vasculature development GO:0001944 70 0.025
reproduction GO:0000003 245 0.025
negative regulation of protein phosphorylation GO:0001933 44 0.025
regulation of cell cycle GO:0051726 73 0.025
camera type eye development GO:0043010 48 0.024
dephosphorylation GO:0016311 98 0.024
response to increased oxygen levels GO:0036296 45 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
positive regulation of cellular component biogenesis GO:0044089 55 0.024
embryonic skeletal system development GO:0048706 3 0.024
anterior posterior pattern specification GO:0009952 1 0.024
cellular divalent inorganic cation homeostasis GO:0072503 162 0.024
peptidyl tyrosine modification GO:0018212 72 0.024
Human Rat
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.024
camp biosynthetic process GO:0006171 47 0.024
regulation of neurotransmitter levels GO:0001505 42 0.024
positive regulation of camp metabolic process GO:0030816 31 0.023
multicellular organismal response to stress GO:0033555 25 0.023
regulation of immune system process GO:0002682 123 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
Human
cellular component biogenesis GO:0044085 368 0.023
Human Mouse
regulation of camp metabolic process GO:0030814 43 0.023
sodium ion transport GO:0006814 82 0.023
negative regulation of secretion by cell GO:1903531 72 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.023
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.023
positive regulation of fear response GO:1903367 3 0.023
negative regulation of signaling GO:0023057 157 0.022
Human
membrane depolarization GO:0051899 32 0.022

Nrg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.113
nervous system disease DOID:863 0 0.113
musculoskeletal system disease DOID:17 0 0.046
connective tissue disease DOID:65 0 0.046
kidney disease DOID:557 0 0.040
urinary system disease DOID:18 0 0.040
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
eye disease DOID:5614 0 0.023