Rattus norvegicus

0 known processes

Nup88

nucleoporin 88

(Aliases: Nup84,Prei2)

Nup88 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.568
rna metabolic process GO:0016070 406 0.545
transcription dna templated GO:0006351 377 0.499
regulation of rna metabolic process GO:0051252 391 0.467
regulation of rna biosynthetic process GO:2001141 381 0.377
positive regulation of rna metabolic process GO:0051254 203 0.330
nucleic acid templated transcription GO:0097659 379 0.313
organelle organization GO:0006996 266 0.270
transcription from rna polymerase ii promoter GO:0006366 252 0.246
positive regulation of gene expression GO:0010628 244 0.236
regulation of transcription dna templated GO:0006355 374 0.215
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.205
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.204
positive regulation of biosynthetic process GO:0009891 319 0.199
regulation of nucleic acid templated transcription GO:1903506 380 0.196
mrna metabolic process GO:0016071 20 0.188
alternative mrna splicing via spliceosome GO:0000380 4 0.187
positive regulation of cellular biosynthetic process GO:0031328 295 0.171
regulation of mrna splicing via spliceosome GO:0048024 3 0.167
positive regulation of transcription dna templated GO:0045893 197 0.165
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.161
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.156
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.150
positive regulation of rna biosynthetic process GO:1902680 197 0.141
negative regulation of rna metabolic process GO:0051253 123 0.120
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.114
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.113
cell cycle GO:0007049 101 0.104
response to peptide hormone GO:0043434 278 0.104
macromolecular complex subunit organization GO:0043933 339 0.102
macromolecular complex assembly GO:0065003 273 0.102
regulation of protein metabolic process GO:0051246 289 0.099
negative regulation of metabolic process GO:0009892 331 0.097
regulation of molecular function GO:0065009 398 0.092
negative regulation of cellular metabolic process GO:0031324 281 0.081
cellular component biogenesis GO:0044085 368 0.078
reproductive process GO:0022414 372 0.077
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.075
positive regulation of nucleic acid templated transcription GO:1903508 197 0.072
protein complex assembly GO:0006461 263 0.070
response to peptide GO:1901652 292 0.069
cellular component assembly GO:0022607 360 0.066
cellular response to peptide GO:1901653 133 0.064
negative regulation of gene expression GO:0010629 199 0.060
regulation of rna splicing GO:0043484 6 0.060
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.059
nucleoside monophosphate catabolic process GO:0009125 56 0.059
ribose phosphate metabolic process GO:0019693 235 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.059
single organism reproductive process GO:0044702 297 0.056
single organism intracellular transport GO:1902582 166 0.056
cellular catabolic process GO:0044248 295 0.051
negative regulation of cellular biosynthetic process GO:0031327 161 0.051
mrna processing GO:0006397 14 0.048
regulation of cellular ketone metabolic process GO:0010565 27 0.046
protein complex subunit organization GO:0071822 302 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.044
cellular response to stress GO:0033554 269 0.044
nucleobase containing compound catabolic process GO:0034655 152 0.044
regulation of apoptotic process GO:0042981 335 0.042
ribonucleotide catabolic process GO:0009261 136 0.041
neuron differentiation GO:0030182 368 0.040
oxoacid metabolic process GO:0043436 290 0.039
organic substance catabolic process GO:1901575 316 0.039
proteolysis GO:0006508 175 0.039
response to hypoxia GO:0001666 231 0.038
negative regulation of nucleic acid templated transcription GO:1903507 117 0.037
cytoskeleton organization GO:0007010 111 0.037
spindle organization GO:0007051 2 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
purine containing compound catabolic process GO:0072523 138 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
purine nucleoside monophosphate catabolic process GO:0009128 55 0.037
central nervous system development GO:0007417 311 0.036
intracellular transport GO:0046907 185 0.036
protein phosphorylation GO:0006468 345 0.035
mitotic spindle organization GO:0007052 2 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
nucleotide metabolic process GO:0009117 279 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
cellular response to peptide hormone stimulus GO:0071375 120 0.035
regulation of cell differentiation GO:0045595 320 0.034
regulation of protein modification process GO:0031399 194 0.034
cellular response to insulin stimulus GO:0032869 81 0.034
neuron development GO:0048666 286 0.034
regulation of programmed cell death GO:0043067 341 0.034
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.034
gamete generation GO:0007276 124 0.034
nucleoside monophosphate metabolic process GO:0009123 93 0.033
negative regulation of transcription dna templated GO:0045892 116 0.033
multi organism reproductive process GO:0044703 262 0.033
purine ribonucleoside metabolic process GO:0046128 168 0.033
response to nutrient GO:0007584 248 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
ribonucleoside catabolic process GO:0042454 126 0.032
negative regulation of programmed cell death GO:0043069 183 0.032
catabolic process GO:0009056 351 0.032
organophosphate metabolic process GO:0019637 370 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
multicellular organismal reproductive process GO:0048609 233 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
purine nucleoside triphosphate metabolic process GO:0009144 141 0.029
amine metabolic process GO:0009308 38 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
positive regulation of developmental process GO:0051094 283 0.029
negative regulation of apoptotic process GO:0043066 181 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
negative regulation of response to stimulus GO:0048585 155 0.028
protein complex biogenesis GO:0070271 263 0.027
reproduction GO:0000003 245 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.027
response to estrogen GO:0043627 232 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
ribonucleoside triphosphate catabolic process GO:0009203 122 0.027
cellular ketone metabolic process GO:0042180 51 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.026
protein transport GO:0015031 132 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
peptidyl amino acid modification GO:0018193 126 0.026
sexual reproduction GO:0019953 148 0.026
programmed cell death GO:0012501 392 0.026
response to oxygen levels GO:0070482 265 0.026
ribonucleoside metabolic process GO:0009119 174 0.025
cell cycle process GO:0022402 57 0.025
purine nucleotide catabolic process GO:0006195 136 0.025
regulation of cell proliferation GO:0042127 359 0.025
chromatin organization GO:0006325 34 0.024
purine nucleoside triphosphate catabolic process GO:0009146 122 0.024
organic acid metabolic process GO:0006082 292 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
centrosome cycle GO:0007098 1 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.023
cytoplasmic transport GO:0016482 115 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
intracellular signal transduction GO:0035556 314 0.023
developmental process involved in reproduction GO:0003006 159 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of mrna processing GO:0050684 5 0.022
aromatic compound catabolic process GO:0019439 168 0.022
regulation of cell cycle GO:0051726 73 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
apoptotic process GO:0006915 381 0.022
mitotic cell cycle GO:0000278 49 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.022
nucleoside phosphate catabolic process GO:1901292 140 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
cell part morphogenesis GO:0032990 123 0.022
single organism catabolic process GO:0044712 283 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
rna processing GO:0006396 22 0.021
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 7 0.021
single organism organelle organization GO:1902589 180 0.021
negative regulation of cell death GO:0060548 229 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
ribonucleotide metabolic process GO:0009259 231 0.020
histone modification GO:0016570 30 0.020
multicellular organism growth GO:0035264 1 0.020
heterocycle catabolic process GO:0046700 167 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
spermatogenesis GO:0007283 99 0.020
cell cycle g1 s phase transition GO:0044843 13 0.020
eye development GO:0001654 50 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
multicellular organism reproduction GO:0032504 233 0.020
embryonic appendage morphogenesis GO:0035113 4 0.020
cell projection organization GO:0030030 302 0.019
protein localization GO:0008104 191 0.019
brain development GO:0007420 247 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
single organism biosynthetic process GO:0044711 342 0.019
purine containing compound metabolic process GO:0072521 253 0.019
positive regulation of cell development GO:0010720 176 0.019
macromolecule catabolic process GO:0009057 58 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
positive regulation of nervous system development GO:0051962 178 0.018
nucleosome organization GO:0034728 1 0.018
male gamete generation GO:0048232 99 0.018
response to extracellular stimulus GO:0009991 380 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
response to metal ion GO:0010038 253 0.018
regulation of cellular component organization GO:0051128 368 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
head development GO:0060322 247 0.017
wound healing GO:0042060 122 0.017
cellular component movement GO:0006928 248 0.017
atp catabolic process GO:0006200 54 0.017
g1 s transition of mitotic cell cycle GO:0000082 12 0.017
regulation of catalytic activity GO:0050790 304 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.016
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.016
nucleoside catabolic process GO:0009164 126 0.016
positive regulation of protein modification process GO:0031401 142 0.016
nucleoside metabolic process GO:0009116 179 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
neuron projection development GO:0031175 273 0.016
neurological system process GO:0050877 219 0.016
regulation of cell development GO:0060284 263 0.016
ribonucleoside monophosphate catabolic process GO:0009158 55 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
tissue development GO:0009888 252 0.015
positive regulation of molecular function GO:0044093 230 0.015
ribose phosphate biosynthetic process GO:0046390 87 0.015
histone methylation GO:0016571 3 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
centrosome organization GO:0051297 1 0.015
cellular macromolecular complex assembly GO:0034622 58 0.015
protein oligomerization GO:0051259 191 0.015
mrna splicing via spliceosome GO:0000398 7 0.014
organ morphogenesis GO:0009887 75 0.014
rna splicing via transesterification reactions GO:0000375 7 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
behavior GO:0007610 205 0.014
regulation of response to stress GO:0080134 126 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
microtubule cytoskeleton organization GO:0000226 25 0.014
organophosphate catabolic process GO:0046434 148 0.014
macromolecule localization GO:0033036 252 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of hydrolase activity GO:0051336 143 0.014
limb morphogenesis GO:0035108 4 0.014
protein processing GO:0016485 68 0.014
sex differentiation GO:0007548 113 0.014
growth GO:0040007 165 0.013
response to insulin GO:0032868 133 0.013
microtubule based process GO:0007017 36 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of signal transduction GO:0009966 318 0.013
regulation of neurogenesis GO:0050767 247 0.013
vesicle mediated transport GO:0016192 181 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
dna geometric change GO:0032392 4 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
response to heat GO:0009408 60 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
mitotic cell cycle process GO:1903047 35 0.013
positive regulation of behavior GO:0048520 38 0.012
action potential GO:0001508 54 0.012
mrna 3 end processing GO:0031124 1 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
chromosome organization GO:0051276 36 0.012
cell cycle phase transition GO:0044770 21 0.012
cell projection morphogenesis GO:0048858 123 0.012
b cell differentiation GO:0030183 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
negative regulation of signaling GO:0023057 157 0.012
response to nutrient levels GO:0031667 370 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
locomotion GO:0040011 237 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
response to inorganic substance GO:0010035 377 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
nucleotide catabolic process GO:0009166 139 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
regulation of locomotion GO:0040012 148 0.011
microtubule organizing center organization GO:0031023 1 0.011
regulation of cellular response to stress GO:0080135 49 0.011
chemical homeostasis GO:0048878 292 0.011
negative regulation of tor signaling GO:0032007 2 0.010
negative regulation of cell communication GO:0010648 158 0.010
nuclear transport GO:0051169 49 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
response to decreased oxygen levels GO:0036293 237 0.010
localization of cell GO:0051674 202 0.010
response to external biotic stimulus GO:0043207 221 0.010
response to biotic stimulus GO:0009607 226 0.010
response to acid chemical GO:0001101 222 0.010
rna splicing GO:0008380 11 0.010

Nup88 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.025
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.014