Rattus norvegicus

16 known processes

Oprk1

opioid receptor, kappa 1

Oprk1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cytosolic calcium ion homeostasis GO:0051480 140 0.634
Rat
positive regulation of transport GO:0051050 245 0.617
Rat
secretion by cell GO:0032940 248 0.537
Rat
neuropeptide signaling pathway GO:0007218 29 0.522
Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.521
Human Rat
cation transmembrane transport GO:0098655 263 0.520
Rat
transmembrane transport GO:0055085 412 0.448
Rat
organelle organization GO:0006996 266 0.445
Rat
regulation of ion transport GO:0043269 245 0.435
Rat
sensory perception GO:0007600 101 0.410
Mouse Rat
synaptic transmission gabaergic GO:0051932 22 0.406
regulation of secretion GO:0051046 224 0.404
Mouse Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.395
Rat
cation transport GO:0006812 382 0.367
Rat
positive regulation of ion transport GO:0043270 94 0.361
nitrogen compound transport GO:0071705 229 0.356
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.334
Rat
blood circulation GO:0008015 183 0.318
head development GO:0060322 247 0.318
Rat
amine transport GO:0015837 57 0.317
regulation of molecular function GO:0065009 398 0.308
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.307
positive regulation of secretion by cell GO:1903532 128 0.301
Rat
monoamine transport GO:0015844 43 0.300
ion transmembrane transport GO:0034220 365 0.294
Rat
synaptic transmission GO:0007268 235 0.285
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.280
macromolecular complex subunit organization GO:0043933 339 0.279
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.279
Rat
response to ammonium ion GO:0060359 71 0.277
Rat
sensory perception of pain GO:0019233 73 0.269
Mouse Rat
regulation of synaptic transmission gabaergic GO:0032228 17 0.267
heart contraction GO:0060047 57 0.267
intracellular signal transduction GO:0035556 314 0.266
Rat
protein phosphorylation GO:0006468 345 0.264
Rat
positive regulation of secretion GO:0051047 140 0.257
Rat
secretion GO:0046903 307 0.255
Mouse Rat
regulation of potassium ion transport GO:0043266 29 0.247
signal transduction by phosphorylation GO:0023014 144 0.227
Rat
response to inorganic substance GO:0010035 377 0.224
regulation of heart rate GO:0002027 16 0.216
heart process GO:0003015 57 0.209
anion transport GO:0006820 178 0.205
Rat
cytokine production GO:0001816 61 0.204
brain development GO:0007420 247 0.201
Rat
positive regulation of catalytic activity GO:0043085 184 0.196
Rat
cellular ion homeostasis GO:0006873 184 0.194
Rat
positive regulation of signaling GO:0023056 270 0.194
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.186
cellular chemical homeostasis GO:0055082 247 0.184
Rat
chemical homeostasis GO:0048878 292 0.183
Rat
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.183
Human Rat
neurological system process GO:0050877 219 0.169
Mouse Rat
calcium ion homeostasis GO:0055074 162 0.168
Rat
regulation of cellular localization GO:0060341 263 0.168
Rat
myeloid leukocyte activation GO:0002274 36 0.167
positive regulation of intracellular signal transduction GO:1902533 138 0.164
Rat
organic acid transport GO:0015849 116 0.161
Rat
cation homeostasis GO:0055080 195 0.155
Rat
cell cell signaling GO:0007267 335 0.155
Rat
positive regulation of signal transduction GO:0009967 175 0.154
Rat
metal ion transport GO:0030001 289 0.152
Rat
circulatory system process GO:0003013 183 0.152
positive regulation of serotonin secretion GO:0014064 1 0.151
cellular metal ion homeostasis GO:0006875 172 0.149
Rat
cellular response to endogenous stimulus GO:0071495 377 0.149
Rat
regulation of neurological system process GO:0031644 43 0.148
Rat
metal ion homeostasis GO:0055065 186 0.146
Rat
protein complex assembly GO:0006461 263 0.144
ion homeostasis GO:0050801 212 0.142
Rat
macromolecule localization GO:0033036 252 0.142
Rat
regulation of system process GO:0044057 208 0.141
Mouse Rat
calcium ion transport GO:0006816 131 0.138
Rat
regulation of rna metabolic process GO:0051252 391 0.137
regulation of catecholamine secretion GO:0050433 32 0.133
mapk cascade GO:0000165 140 0.131
Rat
organic hydroxy compound transport GO:0015850 77 0.131
cellular response to nitrogen compound GO:1901699 210 0.131
Rat
positive regulation of cell communication GO:0010647 271 0.130
Rat
positive regulation of cell proliferation GO:0008284 249 0.125
protein complex subunit organization GO:0071822 302 0.124
Rat
cellular component assembly GO:0022607 360 0.124
Rat
regulation of blood circulation GO:1903522 110 0.121
positive regulation of molecular function GO:0044093 230 0.121
Rat
eating behavior GO:0042755 21 0.117
positive regulation of synaptic transmission GO:0050806 62 0.115
Rat
regulation of heart contraction GO:0008016 48 0.115
regulation of secretion by cell GO:1903530 208 0.115
Rat
regulation of ion transmembrane transport GO:0034765 121 0.113
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.112
Rat
regulation of metal ion transport GO:0010959 118 0.111
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.111
Rat
muscle system process GO:0003012 115 0.110
Rat
cellular response to organic cyclic compound GO:0071407 202 0.110
Rat
somatostatin receptor signaling pathway GO:0038169 4 0.106
Rat
cell activation GO:0001775 97 0.106
intracellular transport GO:0046907 185 0.103
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.103
Human Rat
regulation of amino acid transport GO:0051955 25 0.103
leukocyte activation GO:0045321 76 0.102
regulation of norepinephrine secretion GO:0014061 15 0.102
positive regulation of protein phosphorylation GO:0001934 135 0.102
Rat
actin cytoskeleton organization GO:0030036 73 0.101
Rat
negative regulation of amine transport GO:0051953 24 0.100
purine containing compound metabolic process GO:0072521 253 0.100
Rat
homeostatic process GO:0042592 331 0.100
Rat
regulation of amine transport GO:0051952 54 0.099
positive regulation of biosynthetic process GO:0009891 319 0.099
erk1 and erk2 cascade GO:0070371 48 0.099
Rat
cellular homeostasis GO:0019725 252 0.098
Rat
regulation of muscle system process GO:0090257 79 0.097
Rat
regulation of cytokine production GO:0001817 56 0.097
monovalent inorganic cation transport GO:0015672 172 0.096
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.094
cellular divalent inorganic cation homeostasis GO:0072503 162 0.092
Rat
positive regulation of developmental process GO:0051094 283 0.092
negative regulation of synaptic transmission gabaergic GO:0032229 6 0.091
regulation of protein kinase activity GO:0045859 105 0.091
Rat
central nervous system development GO:0007417 311 0.090
Rat
reproductive process GO:0022414 372 0.089
Rat
cellular component biogenesis GO:0044085 368 0.089
Rat
nucleotide metabolic process GO:0009117 279 0.088
Rat
cellular calcium ion homeostasis GO:0006874 160 0.088
Rat
regulation of protein metabolic process GO:0051246 289 0.088
Rat
response to alkaloid GO:0043279 132 0.088
Rat
protein localization GO:0008104 191 0.087
regulation of calcium ion transport GO:0051924 77 0.087
Rat
regulation of catalytic activity GO:0050790 304 0.086
Rat
regulation of saliva secretion GO:0046877 3 0.086
Mouse
response to acid chemical GO:0001101 222 0.086
cytoskeleton organization GO:0007010 111 0.085
Rat
regulation of cell proliferation GO:0042127 359 0.085
Rat
feeding behavior GO:0007631 53 0.083
actin filament based process GO:0030029 86 0.081
Rat
regulation of protein transport GO:0051223 68 0.081
negative regulation of ion transport GO:0043271 51 0.081
rna metabolic process GO:0016070 406 0.080
catecholamine transport GO:0051937 37 0.079
purine nucleotide metabolic process GO:0006163 229 0.079
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.078
Rat
regulation of cell development GO:0060284 263 0.078
locomotory exploration behavior GO:0035641 1 0.077
positive regulation of nucleotide metabolic process GO:0045981 91 0.077
divalent metal ion transport GO:0070838 132 0.077
Rat
regulation of kinase activity GO:0043549 117 0.076
Rat
norepinephrine secretion GO:0048243 16 0.075
positive regulation of heart rate GO:0010460 9 0.074
response to extracellular stimulus GO:0009991 380 0.072
Rat
positive regulation of phosphorylation GO:0042327 177 0.072
Rat
nucleic acid templated transcription GO:0097659 379 0.071
response to nutrient levels GO:0031667 370 0.071
Rat
positive regulation of protein modification process GO:0031401 142 0.070
Rat
regulation of sensory perception of pain GO:0051930 29 0.069
Rat
carboxylic acid transport GO:0046942 115 0.068
Rat
regulation of phosphate metabolic process GO:0019220 349 0.067
Rat
positive regulation of protein transport GO:0051222 41 0.066
regulation of protein modification process GO:0031399 194 0.066
Rat
regulation of transmembrane transport GO:0034762 122 0.066
Rat
negative regulation of cell communication GO:0010648 158 0.066
positive regulation of calcium ion transport GO:0051928 36 0.066
glutamate secretion GO:0014047 19 0.065
protein oligomerization GO:0051259 191 0.065
ribonucleotide metabolic process GO:0009259 231 0.065
Rat
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.065
positive regulation of mapk cascade GO:0043410 92 0.064
Rat
cellular amine metabolic process GO:0044106 38 0.064
regulation of synaptic transmission GO:0050804 141 0.064
Rat
divalent inorganic cation transport GO:0072511 134 0.063
Rat
oxoacid metabolic process GO:0043436 290 0.062
positive regulation of heart contraction GO:0045823 15 0.062
inorganic cation transmembrane transport GO:0098662 202 0.062
Rat
regulation of rna biosynthetic process GO:2001141 381 0.062
catecholamine secretion GO:0050432 33 0.060
protein complex biogenesis GO:0070271 263 0.059
positive regulation of map kinase activity GO:0043406 46 0.059
Rat
regulation of synaptic transmission glutamatergic GO:0051966 26 0.057
regulation of nucleotide metabolic process GO:0006140 117 0.057
Rat
neuron neuron synaptic transmission GO:0007270 60 0.057
negative regulation of signaling GO:0023057 157 0.057
regulation of cellular amine metabolic process GO:0033238 8 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.054
ribonucleotide biosynthetic process GO:0009260 85 0.054
Rat
protein homooligomerization GO:0051260 91 0.053
cellular amino acid metabolic process GO:0006520 107 0.053
regulation of establishment of protein localization GO:0070201 69 0.053
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
aging GO:0007568 241 0.052
striated muscle contraction GO:0006941 44 0.052
forebrain development GO:0030900 98 0.051
Rat
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.051
activation of protein kinase activity GO:0032147 47 0.051
Rat
positive regulation of cell differentiation GO:0045597 217 0.051
ossification GO:0001503 70 0.050
telencephalon development GO:0021537 62 0.050
single organism intracellular transport GO:1902582 166 0.050
regulation of cell activation GO:0050865 50 0.050
negative regulation of chronic inflammatory response GO:0002677 2 0.049
cellular potassium ion transport GO:0071804 72 0.049
urinary tract smooth muscle contraction GO:0014848 4 0.049
cellular response to corticosteroid stimulus GO:0071384 69 0.049
Rat
regulation of transferase activity GO:0051338 123 0.049
Rat
positive regulation of protein kinase activity GO:0045860 73 0.048
Rat
purine nucleotide biosynthetic process GO:0006164 83 0.047
Rat
regulation of muscle contraction GO:0006937 53 0.047
Rat
establishment of protein localization GO:0045184 141 0.047
organic hydroxy compound metabolic process GO:1901615 115 0.047
Rat
regulation of feeding behavior GO:0060259 14 0.047
synaptic transmission glutamatergic GO:0035249 33 0.046
cellular catabolic process GO:0044248 295 0.046
acid secretion GO:0046717 48 0.045
Rat
stress activated protein kinase signaling cascade GO:0031098 37 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.044
regulation of mapk cascade GO:0043408 116 0.044
Rat
regulation of sensory perception GO:0051931 29 0.044
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.044
Rat
regulation of phosphorylation GO:0042325 248 0.044
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.044
single organism organelle organization GO:1902589 180 0.044
Rat
response to blue light GO:0009637 1 0.044
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.043
positive regulation of protein metabolic process GO:0051247 178 0.043
Rat
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 2 0.042
Human Rat
regulation of actin filament based process GO:0032970 42 0.042
Rat
camp biosynthetic process GO:0006171 47 0.042
Rat
reproduction GO:0000003 245 0.042
Rat
urinary bladder smooth muscle contraction GO:0014832 4 0.041
digestive system process GO:0022600 24 0.041
Mouse
micturition GO:0060073 4 0.041
response to corticosteroid GO:0031960 235 0.041
Rat
regulation of signal transduction GO:0009966 318 0.041
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.041
Rat
positive regulation of cytokine production GO:0001819 42 0.039
negative regulation of defecation GO:2000293 1 0.039
multi organism reproductive process GO:0044703 262 0.039
Rat
immune system process GO:0002376 204 0.039
Human Rat
cellular cation homeostasis GO:0030003 180 0.039
Rat
organ regeneration GO:0031100 101 0.039
synaptic transmission glycinergic GO:0060012 2 0.039
negative regulation of response to stimulus GO:0048585 155 0.039
regulation of blood pressure GO:0008217 83 0.039
regulation of blood vessel size GO:0050880 89 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.038
regulation of nucleotide biosynthetic process GO:0030808 47 0.038
Rat
regulation of endocrine process GO:0044060 21 0.037
regulation of protein localization GO:0032880 81 0.037
amine metabolic process GO:0009308 38 0.037
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.037
positive regulation of lymphocyte proliferation GO:0050671 20 0.037
positive regulation of nucleic acid templated transcription GO:1903508 197 0.036
renal system process GO:0003014 40 0.036
regulation of excretion GO:0044062 21 0.036
locomotion GO:0040011 237 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
Rat
serotonin receptor signaling pathway GO:0007210 10 0.036
regulation of neuron death GO:1901214 115 0.036
positive regulation of response to external stimulus GO:0032103 51 0.036
Rat
regulation of hormone secretion GO:0046883 106 0.036
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.035
catabolic process GO:0009056 351 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
monocarboxylic acid transport GO:0015718 52 0.035
Rat
negative regulation of transport GO:0051051 136 0.035
organonitrogen compound biosynthetic process GO:1901566 167 0.035
Rat
regulation of homeostatic process GO:0032844 101 0.035
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.034
positive regulation of protein secretion GO:0050714 19 0.034
second messenger mediated signaling GO:0019932 51 0.034
Rat
response to oxygen levels GO:0070482 265 0.034
regulation of protein phosphorylation GO:0001932 183 0.034
Rat
rna biosynthetic process GO:0032774 380 0.034
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.033
positive regulation of saliva secretion GO:0046878 3 0.033
regulation of hormone levels GO:0010817 187 0.033
Rat
negative regulation of molecular function GO:0044092 133 0.033
Rat
protein heterooligomerization GO:0051291 89 0.033
cellular component morphogenesis GO:0032989 155 0.033
regulation of smooth muscle contraction GO:0006940 29 0.033
behavior GO:0007610 205 0.033
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.033
regulation of purine nucleotide metabolic process GO:1900542 115 0.033
Rat
single organism catabolic process GO:0044712 283 0.032
small molecule biosynthetic process GO:0044283 124 0.032
cellular ketone metabolic process GO:0042180 51 0.032
immune response GO:0006955 104 0.032
Human Rat
multicellular organismal homeostasis GO:0048871 49 0.032
signal release GO:0023061 145 0.031
Rat
negative regulation of calcium ion import GO:0090281 2 0.031
nucleoside catabolic process GO:0009164 126 0.031
negative regulation of blood vessel morphogenesis GO:2000181 10 0.031
response to estrogen GO:0043627 232 0.031
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.031
Rat
regulation of ossification GO:0030278 32 0.031
action potential GO:0001508 54 0.031
sequestering of calcium ion GO:0051208 8 0.030
learning or memory GO:0007611 90 0.030
single organism behavior GO:0044708 130 0.030
single organism cellular localization GO:1902580 102 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
Rat
regulation of programmed cell death GO:0043067 341 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
Rat
positive regulation of synaptic transmission gabaergic GO:0032230 9 0.030
positive regulation of cell activation GO:0050867 34 0.030
cellular protein localization GO:0034613 122 0.030
apoptotic process GO:0006915 381 0.029
synaptic transmission cholinergic GO:0007271 11 0.029
prepulse inhibition GO:0060134 1 0.029
regulation of glutamate secretion GO:0014048 17 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.028
Rat
gastric motility GO:0035482 3 0.028
regulation of apoptotic process GO:0042981 335 0.028
regulation of body fluid levels GO:0050878 90 0.028
Mouse
cyclic purine nucleotide metabolic process GO:0052652 62 0.028
Rat
positive regulation of blood circulation GO:1903524 65 0.028
negative regulation of signal transduction GO:0009968 83 0.028
negative regulation of defense response GO:0031348 19 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
tissue development GO:0009888 252 0.028
regulation of action potential GO:0098900 14 0.028
response to ethanol GO:0045471 162 0.028
Rat
hormone secretion GO:0046879 115 0.028
Rat
protein transport GO:0015031 132 0.027
regulation of behavior GO:0050795 61 0.027
muscle contraction GO:0006936 88 0.027
Rat
peptidyl tyrosine modification GO:0018212 72 0.027
regulation of cytoskeleton organization GO:0051493 49 0.027
Rat
response to peptide hormone GO:0043434 278 0.027
regulation of erk1 and erk2 cascade GO:0070372 41 0.027
Rat
organic acid metabolic process GO:0006082 292 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
Rat
cellular response to hormone stimulus GO:0032870 247 0.026
Rat
regulation of transcription dna templated GO:0006355 374 0.026
defense response GO:0006952 194 0.025
Human Rat
positive regulation of catecholamine secretion GO:0033605 13 0.025
regulation of response to external stimulus GO:0032101 106 0.025
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.025
positive regulation of leukocyte degranulation GO:0043302 4 0.025
respiratory gaseous exchange GO:0007585 4 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
negative regulation of smooth muscle contraction GO:0045986 7 0.025
response to histamine GO:0034776 3 0.025
rhythmic process GO:0048511 156 0.024
regulation of hydrolase activity GO:0051336 143 0.024
positive regulation of mast cell activation GO:0033005 4 0.024
ribose phosphate biosynthetic process GO:0046390 87 0.024
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.024
Rat
negative regulation of nucleotide biosynthetic process GO:0030809 12 0.024
Rat
inflammatory response GO:0006954 150 0.024
Rat
regulation of inflammatory response GO:0050727 48 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.023
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.023
Rat
peristalsis GO:0030432 2 0.023
Rat
nucleotide biosynthetic process GO:0009165 98 0.023
Rat
choline transport GO:0015871 4 0.023
macromolecular complex assembly GO:0065003 273 0.023
regulation of tube size GO:0035150 89 0.023
anatomical structure formation involved in morphogenesis GO:0048646 83 0.023
norepinephrine transport GO:0015874 18 0.023
cell motility GO:0048870 202 0.023
defecation GO:0030421 1 0.022
lipid localization GO:0010876 62 0.022
Rat
positive regulation of stress activated mapk cascade GO:0032874 17 0.022
ribonucleoside triphosphate catabolic process GO:0009203 122 0.022
regulation of protein serine threonine kinase activity GO:0071900 64 0.022
Rat
regulation of protein secretion GO:0050708 28 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.022
ras protein signal transduction GO:0007265 29 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
Rat
temperature homeostasis GO:0001659 17 0.021
potassium ion transport GO:0006813 97 0.021
positive regulation of blood pressure GO:0045777 31 0.021
negative regulation of muscle contraction GO:0045932 8 0.021
purine nucleotide catabolic process GO:0006195 136 0.021
salivary gland development GO:0007431 3 0.021
lung development GO:0030324 43 0.021
regulation of cell differentiation GO:0045595 320 0.021
regulation of eosinophil chemotaxis GO:2000422 1 0.021
protein secretion GO:0009306 34 0.021
regulation of response to wounding GO:1903034 69 0.021
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.021
positive regulation of homeostatic process GO:0032846 49 0.021
transcription dna templated GO:0006351 377 0.021
positive regulation of response to wounding GO:1903036 34 0.020
regulation of organelle organization GO:0033043 80 0.020
Rat
peptide transport GO:0015833 97 0.020
follicle stimulating hormone secretion GO:0046884 5 0.020
saliva secretion GO:0046541 3 0.020
Mouse
cell projection morphogenesis GO:0048858 123 0.020
positive regulation of cell development GO:0010720 176 0.020
dopamine secretion GO:0014046 15 0.020
response to cocaine GO:0042220 39 0.020
Rat
cellular response to glucocorticoid stimulus GO:0071385 68 0.020
Rat
response to wounding GO:0009611 254 0.020
Rat
negative regulation of secretion GO:0051048 82 0.020
cognition GO:0050890 92 0.020
multicellular organism growth GO:0035264 1 0.020
regulation of follicle stimulating hormone secretion GO:0046880 5 0.020
positive regulation of dopamine secretion GO:0033603 8 0.020
cellular component movement GO:0006928 248 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
regulation of synaptic plasticity GO:0048167 70 0.019
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.019
programmed cell death GO:0012501 392 0.019
cellular macromolecule localization GO:0070727 122 0.019
regulation of anion transport GO:0044070 43 0.019
renal system development GO:0072001 67 0.019
alcohol metabolic process GO:0006066 77 0.019
Rat
organ morphogenesis GO:0009887 75 0.019
peptidyl tyrosine phosphorylation GO:0018108 72 0.019
organophosphate metabolic process GO:0019637 370 0.019
Rat
single organism biosynthetic process GO:0044711 342 0.019
Rat
positive regulation of amine transport GO:0051954 26 0.019
positive regulation of long term synaptic potentiation GO:1900273 4 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
regulation of anatomical structure size GO:0090066 135 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
Rat
positive regulation of adenylate cyclase activity GO:0045762 12 0.019
cellular response to ammonium ion GO:0071242 17 0.019
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.019
maintenance of location GO:0051235 17 0.018
tube development GO:0035295 89 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
positive regulation of mononuclear cell proliferation GO:0032946 20 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
response to estradiol GO:0032355 164 0.018
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
Rat
single organism membrane organization GO:0044802 74 0.018
sodium ion transmembrane transport GO:0035725 67 0.018
transmission of nerve impulse GO:0019226 42 0.018
positive regulation of catabolic process GO:0009896 78 0.018
regulation of catabolic process GO:0009894 113 0.017
dicarboxylic acid transport GO:0006835 34 0.017
vasoconstriction GO:0042310 54 0.017
polyol metabolic process GO:0019751 20 0.017
Rat
glycosyl compound catabolic process GO:1901658 126 0.017
cardiac muscle contraction GO:0060048 27 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
Rat
circadian rhythm GO:0007623 88 0.017
positive regulation of camp biosynthetic process GO:0030819 28 0.017
negative regulation of luteinizing hormone secretion GO:0033685 4 0.017
multicellular organismal signaling GO:0035637 44 0.017
protein localization to membrane GO:0072657 36 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
response to ketone GO:1901654 182 0.017
positive regulation of nucleoside metabolic process GO:0045979 55 0.017
nucleotide catabolic process GO:0009166 139 0.017
negative regulation of cell death GO:0060548 229 0.016
positive regulation of exocytosis GO:0045921 19 0.016
positive regulation of intracellular transport GO:0032388 39 0.016
regulation of defecation GO:2000292 1 0.016
lipid transport GO:0006869 61 0.016
Rat
l glutamate import GO:0051938 2 0.016
circadian sleep wake cycle wakefulness GO:0042746 2 0.016
dopamine transport GO:0015872 18 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
cytoplasmic transport GO:0016482 115 0.016
cellular response to stress GO:0033554 269 0.016
angiotensin mediated drinking behavior GO:0003051 2 0.016
regulation of membrane potential GO:0042391 110 0.016
Rat
regulation of leukocyte proliferation GO:0070663 26 0.016
aromatic compound catabolic process GO:0019439 168 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
positive regulation of gene expression GO:0010628 244 0.016
negative regulation of long term synaptic potentiation GO:1900272 1 0.016
regulation of interleukin 6 production GO:0032675 12 0.016
vascular process in circulatory system GO:0003018 96 0.016
gastric inhibitory peptide signaling pathway GO:0038192 1 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of secretion by cell GO:1903531 72 0.016
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.015
Rat
regulation of cellular component organization GO:0051128 368 0.015
Rat
negative regulation of homeostatic process GO:0032845 47 0.015
angioblast cell migration GO:0035476 1 0.015
inflammatory response to antigenic stimulus GO:0002437 18 0.015
Rat
detection of stimulus GO:0051606 24 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
regulation of renin secretion into blood stream GO:1900133 1 0.015
release of sequestered calcium ion into cytosol GO:0051209 25 0.015
cellular response to histamine GO:0071420 3 0.015
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.015
Rat
sequestering of metal ion GO:0051238 9 0.015
uterine smooth muscle contraction GO:0070471 10 0.015
cell projection organization GO:0030030 302 0.015
positive regulation of nervous system development GO:0051962 178 0.014
copulation GO:0007620 17 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
regulation of neuronal synaptic plasticity GO:0048168 31 0.014
response to mechanical stimulus GO:0009612 134 0.014

Oprk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024