Rattus norvegicus

0 known processes

Otx1

orthodenticle homeobox 1

(Aliases: OTX1X)

Otx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.685
Rat Fly
positive regulation of developmental process GO:0051094 283 0.380
Rat Fly
regulation of cell differentiation GO:0045595 320 0.379
Rat Fly
negative regulation of cell differentiation GO:0045596 99 0.371
sensory perception of pain GO:0019233 73 0.323
regulation of multicellular organismal development GO:2000026 376 0.308
Rat Fly
neuron differentiation GO:0030182 368 0.278
Rat Worm Fly
regulation of phosphorus metabolic process GO:0051174 349 0.276
regulation of signal transduction GO:0009966 318 0.257
regulation of transcription dna templated GO:0006355 374 0.257
Human Mouse Worm Fly
regulation of neurogenesis GO:0050767 247 0.241
Rat Fly
transcription dna templated GO:0006351 377 0.233
Human Mouse Worm Fly
negative regulation of nucleic acid templated transcription GO:1903507 117 0.231
Fly
biological adhesion GO:0022610 110 0.225
regulation of cellular component organization GO:0051128 368 0.217
cell projection organization GO:0030030 302 0.217
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.204
Human Mouse Worm Fly
brain development GO:0007420 247 0.203
Zebrafish Mouse Fly
regulation of phosphorylation GO:0042325 248 0.197
cell projection morphogenesis GO:0048858 123 0.196
Fly
neuron development GO:0048666 286 0.189
Fly
sodium ion transport GO:0006814 82 0.184
respiratory system development GO:0060541 45 0.175
angiogenesis GO:0001525 53 0.170
locomotion GO:0040011 237 0.169
neuron projection morphogenesis GO:0048812 122 0.167
Fly
regulation of nervous system development GO:0051960 264 0.167
Rat Fly
response to wounding GO:0009611 254 0.165
cellular response to endogenous stimulus GO:0071495 377 0.164
apoptotic process GO:0006915 381 0.164
behavior GO:0007610 205 0.161
Worm
regulation of cell proliferation GO:0042127 359 0.160
negative regulation of transcription dna templated GO:0045892 116 0.160
Fly
positive regulation of cell differentiation GO:0045597 217 0.156
Rat Fly
positive regulation of signaling GO:0023056 270 0.153
anatomical structure morphogenesis GO:0009653 298 0.148
Mouse Fly
positive regulation of transport GO:0051050 245 0.147
gliogenesis GO:0042063 93 0.146
central nervous system development GO:0007417 311 0.143
Zebrafish Mouse Fly
negative regulation of gene expression GO:0010629 199 0.141
Fly
neurological system process GO:0050877 219 0.139
Worm
neuron projection development GO:0031175 273 0.138
Fly
response to extracellular stimulus GO:0009991 380 0.132
positive regulation of cell proliferation GO:0008284 249 0.131
positive regulation of phosphorus metabolic process GO:0010562 262 0.128
regulation of ion transport GO:0043269 245 0.123
metal ion transport GO:0030001 289 0.123
negative regulation of multicellular organismal process GO:0051241 203 0.122
response to estradiol GO:0032355 164 0.122
growth GO:0040007 165 0.120
positive regulation of cell communication GO:0010647 271 0.119
cell part morphogenesis GO:0032990 123 0.119
Fly
amino acid transport GO:0006865 70 0.118
cation transport GO:0006812 382 0.112
negative regulation of cellular biosynthetic process GO:0031327 161 0.112
Fly
single organism reproductive process GO:0044702 297 0.111
positive regulation of biosynthetic process GO:0009891 319 0.110
Human Worm Fly
cell motility GO:0048870 202 0.108
head development GO:0060322 247 0.108
Zebrafish Mouse Fly
positive regulation of cell development GO:0010720 176 0.105
Rat Fly
response to cytokine GO:0034097 215 0.104
regulation of cellular protein metabolic process GO:0032268 267 0.104
programmed cell death GO:0012501 392 0.104
intracellular signal transduction GO:0035556 314 0.103
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.103
Fly
negative regulation of rna metabolic process GO:0051253 123 0.102
Fly
rna metabolic process GO:0016070 406 0.101
Human Mouse Worm Fly
skeletal system development GO:0001501 41 0.101
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.100
Human Mouse Worm Fly
amine metabolic process GO:0009308 38 0.099
positive regulation of nervous system development GO:0051962 178 0.099
Rat Fly
nucleic acid templated transcription GO:0097659 379 0.099
Human Mouse Worm Fly
regulation of system process GO:0044057 208 0.098
transmembrane transport GO:0055085 412 0.096
cell growth GO:0016049 104 0.093
tissue development GO:0009888 252 0.093
Zebrafish Fly
cell cell signaling GO:0007267 335 0.093
synapse organization GO:0050808 46 0.093
wound healing GO:0042060 122 0.092
response to inorganic substance GO:0010035 377 0.092
cellular homeostasis GO:0019725 252 0.092
regulation of anatomical structure size GO:0090066 135 0.090
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.090
Fly
secretion by cell GO:0032940 248 0.087
positive regulation of response to stimulus GO:0048584 285 0.087
cell morphogenesis GO:0000902 142 0.086
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.086
Human Worm Fly
protein phosphorylation GO:0006468 345 0.085
response to corticosteroid GO:0031960 235 0.085
regulation of cell development GO:0060284 263 0.084
Rat Fly
cellular ketone metabolic process GO:0042180 51 0.082
phasic smooth muscle contraction GO:0014821 3 0.082
negative regulation of neurogenesis GO:0050768 78 0.082
tube development GO:0035295 89 0.081
Zebrafish
negative regulation of cell development GO:0010721 82 0.080
single organism behavior GO:0044708 130 0.079
Worm
regulation of anatomical structure morphogenesis GO:0022603 141 0.079
Fly
positive regulation of phosphorylation GO:0042327 177 0.078
response to mineralocorticoid GO:0051385 49 0.077
negative regulation of metabolic process GO:0009892 331 0.075
Fly
homeostatic process GO:0042592 331 0.074
regulation of growth GO:0040008 105 0.072
negative regulation of developmental process GO:0051093 125 0.072
monovalent inorganic cation transport GO:0015672 172 0.072
positive regulation of apoptotic process GO:0043065 154 0.071
positive regulation of secretion by cell GO:1903532 128 0.071
regulation of protein metabolic process GO:0051246 289 0.071
response to growth factor GO:0070848 189 0.070
negative regulation of macromolecule metabolic process GO:0010605 260 0.070
Fly
localization of cell GO:0051674 202 0.068
regulation of neuron projection development GO:0010975 161 0.068
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.068
Fly
cellular component biogenesis GO:0044085 368 0.067
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.067
single organism biosynthetic process GO:0044711 342 0.067
cellular response to hormone stimulus GO:0032870 247 0.067
positive regulation of cell death GO:0010942 184 0.067
regulation of rna metabolic process GO:0051252 391 0.066
Human Mouse Worm Fly
aging GO:0007568 241 0.066
positive regulation of cellular component organization GO:0051130 200 0.066
rna biosynthetic process GO:0032774 380 0.065
Human Mouse Worm Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.065
regulation of membrane potential GO:0042391 110 0.064
regeneration GO:0031099 163 0.064
reproductive structure development GO:0048608 128 0.064
mapk cascade GO:0000165 140 0.062
negative regulation of apoptotic process GO:0043066 181 0.062
regulation of apoptotic process GO:0042981 335 0.062
regulation of protein modification process GO:0031399 194 0.062
regulation of cellular amino acid metabolic process GO:0006521 2 0.062
organ formation GO:0048645 3 0.061
rhythmic process GO:0048511 156 0.061
Rat
positive regulation of signal transduction GO:0009967 175 0.061
cellular component morphogenesis GO:0032989 155 0.061
Fly
regulation of jun kinase activity GO:0043506 10 0.061
positive regulation of phosphate metabolic process GO:0045937 262 0.060
negative regulation of biosynthetic process GO:0009890 168 0.058
Fly
reproductive system development GO:0061458 128 0.057
positive regulation of gene expression GO:0010628 244 0.055
Human Worm Fly
positive regulation of programmed cell death GO:0043068 157 0.055
response to nutrient levels GO:0031667 370 0.055
forebrain development GO:0030900 98 0.054
Mouse
estrous cycle phase GO:0060206 15 0.053
organic acid metabolic process GO:0006082 292 0.053
cellular response to oxygen containing compound GO:1901701 386 0.053
cellular chemical homeostasis GO:0055082 247 0.053
regulation of protein phosphorylation GO:0001932 183 0.052
protein complex subunit organization GO:0071822 302 0.052
reproductive process GO:0022414 372 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.050
Fly
regulation of cellular amine metabolic process GO:0033238 8 0.050
organ morphogenesis GO:0009887 75 0.050
Mouse Fly
response to estrogen GO:0043627 232 0.049
regulation of secretion by cell GO:1903530 208 0.049
development of primary sexual characteristics GO:0045137 107 0.048
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.048
Fly
negative regulation of programmed cell death GO:0043069 183 0.048
positive regulation of neurogenesis GO:0050769 165 0.048
Rat Fly
negative regulation of rna biosynthetic process GO:1902679 118 0.048
Fly
cell adhesion GO:0007155 110 0.047
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.047
Fly
muscle structure development GO:0061061 87 0.046
response to glucocorticoid GO:0051384 223 0.046
heart process GO:0003015 57 0.046
regulation of synaptic plasticity GO:0048167 70 0.045
positive regulation of rna biosynthetic process GO:1902680 197 0.045
Human Worm Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.044
Fly
organonitrogen compound biosynthetic process GO:1901566 167 0.044
cellular response to organic cyclic compound GO:0071407 202 0.044
response to glucose GO:0009749 136 0.044
regulation of cellular localization GO:0060341 263 0.043
regulation of intracellular signal transduction GO:1902531 218 0.043
cellular response to growth factor stimulus GO:0071363 162 0.043
negative regulation of neuron differentiation GO:0045665 62 0.043
regulation of developmental growth GO:0048638 45 0.043
axon development GO:0061564 96 0.042
regulation of transferase activity GO:0051338 123 0.042
response to mechanical stimulus GO:0009612 134 0.042
negative regulation of cell proliferation GO:0008285 119 0.042
regulation of hormone levels GO:0010817 187 0.042
developmental growth GO:0048589 100 0.042
positive regulation of protein modification process GO:0031401 142 0.041
cellular response to stress GO:0033554 269 0.041
response to hexose GO:0009746 144 0.041
hormone secretion GO:0046879 115 0.040
positive regulation of nucleic acid templated transcription GO:1903508 197 0.040
Human Worm Fly
regulation of neuron differentiation GO:0045664 208 0.040
Rat Fly
positive regulation of growth GO:0045927 55 0.039
regulation of secretion GO:0051046 224 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.039
Human Mouse Worm Fly
regulation of rna biosynthetic process GO:2001141 381 0.038
Human Mouse Worm Fly
circadian rhythm GO:0007623 88 0.038
Rat
regulation of cell cycle GO:0051726 73 0.038
response to tumor necrosis factor GO:0034612 56 0.038
positive regulation of protein phosphorylation GO:0001934 135 0.037
positive regulation of mapk cascade GO:0043410 92 0.037
muscle system process GO:0003012 115 0.037
camera type eye development GO:0043010 48 0.037
Zebrafish
epithelial cell proliferation GO:0050673 54 0.037
gonad development GO:0008406 104 0.037
regulation of body fluid levels GO:0050878 90 0.036
regulation of inflammatory response GO:0050727 48 0.036
oxoacid metabolic process GO:0043436 290 0.036
cellular component assembly GO:0022607 360 0.036
hematopoietic progenitor cell differentiation GO:0002244 2 0.035
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
positive regulation of developmental growth GO:0048639 29 0.034
negative regulation of transport GO:0051051 136 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
muscle tissue development GO:0060537 58 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
Human Worm Fly
reproduction GO:0000003 245 0.034
response to ketone GO:1901654 182 0.033
cellular response to peptide hormone stimulus GO:0071375 120 0.033
inflammatory response GO:0006954 150 0.033
enzyme linked receptor protein signaling pathway GO:0007167 116 0.033
cellular response to lipid GO:0071396 201 0.033
embryonic skeletal system development GO:0048706 3 0.033
heart contraction GO:0060047 57 0.032
epithelium development GO:0060429 96 0.032
Zebrafish
cellular metal ion homeostasis GO:0006875 172 0.032
axonogenesis GO:0007409 71 0.032
response to peptide GO:1901652 292 0.032
cell migration GO:0016477 197 0.032
palate development GO:0060021 2 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.031
regulation of homeostatic process GO:0032844 101 0.031
protein complex biogenesis GO:0070271 263 0.031
response to peptide hormone GO:0043434 278 0.031
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.031
negative regulation of cell death GO:0060548 229 0.031
cellular amine metabolic process GO:0044106 38 0.031
positive regulation of secretion GO:0051047 140 0.031
regulation of cellular catabolic process GO:0031329 101 0.030
developmental process involved in reproduction GO:0003006 159 0.030
response to alkaloid GO:0043279 132 0.030
response to hydrogen peroxide GO:0042542 89 0.030
chemical homeostasis GO:0048878 292 0.030
protein complex assembly GO:0006461 263 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
regulation of cell adhesion GO:0030155 52 0.030
regulation of kinase activity GO:0043549 117 0.030
cell cycle GO:0007049 101 0.029
eye development GO:0001654 50 0.029
Zebrafish Fly
multicellular organism growth GO:0035264 1 0.029
regulation of cellular component movement GO:0051270 150 0.029
positive regulation of cell motility GO:2000147 97 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
Human Worm Fly
response to oxygen levels GO:0070482 265 0.028
response to molecule of bacterial origin GO:0002237 194 0.028
urinary bladder smooth muscle contraction GO:0014832 4 0.028
intracellular transport GO:0046907 185 0.028
calcium ion homeostasis GO:0055074 162 0.028
acid secretion GO:0046717 48 0.027
regulation of cell motility GO:2000145 131 0.027
circulatory system process GO:0003013 183 0.027
synaptic transmission GO:0007268 235 0.027
liver development GO:0001889 90 0.027
muscle contraction GO:0006936 88 0.026
protein localization GO:0008104 191 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.026
gland development GO:0048732 155 0.026
motor neuron axon guidance GO:0008045 1 0.026
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.026
catabolic process GO:0009056 351 0.026
positive regulation of cardiac muscle tissue development GO:0055025 9 0.026
cellular response to cytokine stimulus GO:0071345 127 0.026
cellular response to acid chemical GO:0071229 75 0.026
cellular response to peptide GO:1901653 133 0.025
regulation of sensory perception GO:0051931 29 0.025
response to vitamin GO:0033273 131 0.025
cellular response to tumor necrosis factor GO:0071356 46 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
n methyl d aspartate receptor clustering GO:0097114 2 0.025
male gonad development GO:0008584 59 0.025
positive regulation of molecular function GO:0044093 230 0.025
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
respiratory gaseous exchange GO:0007585 4 0.024
cellular ion homeostasis GO:0006873 184 0.024
regulation of canonical wnt signaling pathway GO:0060828 4 0.024
lymphoid progenitor cell differentiation GO:0002320 2 0.024
negative regulation of secretion by cell GO:1903531 72 0.024
regulation of muscle organ development GO:0048634 26 0.024
organ regeneration GO:0031100 101 0.024
response to electrical stimulus GO:0051602 56 0.024
glutamate secretion GO:0014047 19 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regulation of cell projection organization GO:0031344 175 0.024
protein localization to membrane GO:0072657 36 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.023
signal release GO:0023061 145 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
anatomical structure formation involved in morphogenesis GO:0048646 83 0.023
cardiac chamber development GO:0003205 1 0.023
hepaticobiliary system development GO:0061008 90 0.023
regulation of mapk cascade GO:0043408 116 0.023
purine nucleoside monophosphate metabolic process GO:0009126 84 0.023
regulation of programmed cell death GO:0043067 341 0.023
positive regulation of jnk cascade GO:0046330 13 0.023
response to nutrient GO:0007584 248 0.023
positive regulation of long term synaptic potentiation GO:1900273 4 0.022
single organismal cell cell adhesion GO:0016337 42 0.022
ribose phosphate biosynthetic process GO:0046390 87 0.022
regulation of hormone secretion GO:0046883 106 0.022
cellular component movement GO:0006928 248 0.022
macromolecular complex assembly GO:0065003 273 0.022
glial cell differentiation GO:0010001 65 0.022
regulation of locomotion GO:0040012 148 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.022
renal system process GO:0003014 40 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.022
muscle cell proliferation GO:0033002 84 0.022
anterior posterior pattern specification GO:0009952 1 0.022
Zebrafish Mouse
negative regulation of nervous system development GO:0051961 79 0.022
purine nucleotide biosynthetic process GO:0006164 83 0.021
regulation of protein kinase activity GO:0045859 105 0.021
positive regulation of cellular component movement GO:0051272 102 0.021
regulation of molecular function GO:0065009 398 0.021
specification of organ identity GO:0010092 2 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
ion homeostasis GO:0050801 212 0.021
sex differentiation GO:0007548 113 0.021
response to oxidative stress GO:0006979 186 0.021
respiratory system process GO:0003016 3 0.021
jnk cascade GO:0007254 28 0.021
cellular response to abiotic stimulus GO:0071214 85 0.021
generation of precursor metabolites and energy GO:0006091 62 0.021
lung development GO:0030324 43 0.020
hormone transport GO:0009914 121 0.020
regulation of saliva secretion GO:0046877 3 0.020
negative regulation of cell communication GO:0010648 158 0.020
regulation of response to external stimulus GO:0032101 106 0.020
regulation of sensory perception of pain GO:0051930 29 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
Human Worm Fly
response to osmotic stress GO:0006970 42 0.020
peptidyl amino acid modification GO:0018193 126 0.020
response to lipopolysaccharide GO:0032496 191 0.020
circulatory system development GO:0072359 134 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
Human Worm Fly
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.020
blood vessel development GO:0001568 69 0.019
regulation of renal sodium excretion GO:0035813 20 0.019
regulation of organ formation GO:0003156 2 0.019
regulation of cell migration GO:0030334 128 0.019
single organism cell adhesion GO:0098602 46 0.019
blood circulation GO:0008015 183 0.019
dicarboxylic acid transport GO:0006835 34 0.019
thyroid gland development GO:0030878 1 0.019
neuron neuron synaptic transmission GO:0007270 60 0.019
response to toxic substance GO:0009636 133 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
secretion GO:0046903 307 0.019
heart development GO:0007507 72 0.019
smooth muscle cell proliferation GO:0048659 77 0.019
organophosphate metabolic process GO:0019637 370 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
b cell differentiation GO:0030183 2 0.019
positive regulation of map kinase activity GO:0043406 46 0.018
sodium ion transmembrane transport GO:0035725 67 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
mesoderm development GO:0007498 2 0.018
positive regulation of cardiac muscle tissue growth GO:0055023 9 0.018
regulation of cellular component biogenesis GO:0044087 86 0.018
cellular catabolic process GO:0044248 295 0.018
ras protein signal transduction GO:0007265 29 0.018
excretion GO:0007588 24 0.018
cardiovascular system development GO:0072358 134 0.018
gastrulation GO:0007369 2 0.018
regulation of neurological system process GO:0031644 43 0.018
developmental growth involved in morphogenesis GO:0060560 33 0.018
regulation of map kinase activity GO:0043405 53 0.018
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 1 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
Human Worm Fly
positive regulation of saliva secretion GO:0046878 3 0.018
smooth muscle contraction GO:0006939 37 0.018
lipid biosynthetic process GO:0008610 128 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
ossification GO:0001503 70 0.017
regulation of catalytic activity GO:0050790 304 0.017
adult locomotory behavior GO:0008344 4 0.017
positive regulation of response to wounding GO:1903036 34 0.017
anion transport GO:0006820 178 0.017
response to radiation GO:0009314 137 0.017
regulation of axonogenesis GO:0050770 37 0.017
immune system process GO:0002376 204 0.017
developmental induction GO:0031128 2 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
positive regulation of muscle organ development GO:0048636 13 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
positive regulation of locomotion GO:0040017 102 0.017
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.017
cognition GO:0050890 92 0.017
cyclic nucleotide biosynthetic process GO:0009190 63 0.017
cellular response to corticosteroid stimulus GO:0071384 69 0.016
regulation of protein localization GO:0032880 81 0.016
single organism intracellular transport GO:1902582 166 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
regulation of heart contraction GO:0008016 48 0.016
regulation of response to wounding GO:1903034 69 0.016
eye morphogenesis GO:0048592 4 0.016
Fly
ion transmembrane transport GO:0034220 365 0.016
stress activated mapk cascade GO:0051403 35 0.016
chemotaxis GO:0006935 66 0.016
bone development GO:0060348 25 0.016
organ induction GO:0001759 1 0.016
regulation of stem cell differentiation GO:2000736 2 0.016
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.016
regulation of fat cell differentiation GO:0045598 3 0.016
regulation of cell growth GO:0001558 85 0.016
response to reactive oxygen species GO:0000302 120 0.016
response to ethanol GO:0045471 162 0.016
positive regulation of brown fat cell proliferation GO:0070349 1 0.016
regulation of cellular response to stress GO:0080135 49 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
regulation of muscle system process GO:0090257 79 0.016
learning or memory GO:0007611 90 0.016
l glutamate import GO:0051938 2 0.016
odontogenesis GO:0042476 32 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.015
morphogenesis of an epithelium GO:0002009 20 0.015
positive regulation of cell growth GO:0030307 44 0.015
regulation of metal ion transport GO:0010959 118 0.015
regulation of ossification GO:0030278 32 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
positive regulation of blood pressure GO:0045777 31 0.015
divalent inorganic cation transport GO:0072511 134 0.015
peptide hormone secretion GO:0030072 84 0.015
carbohydrate homeostasis GO:0033500 75 0.015
regulation of response to stress GO:0080134 126 0.015
positive regulation of organelle organization GO:0010638 48 0.015
cellular response to estradiol stimulus GO:0071392 16 0.015
regulation of cell cell adhesion GO:0022407 14 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
Rat Fly
negative regulation of signaling GO:0023057 157 0.015
regulation of organ morphogenesis GO:2000027 22 0.015
Fly
cell cycle process GO:0022402 57 0.015
negative regulation of secretion GO:0051048 82 0.015
wnt signaling pathway GO:0016055 17 0.015
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
coronary vasculature morphogenesis GO:0060977 3 0.015
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.015
tissue morphogenesis GO:0048729 22 0.015
negative regulation of calcium ion transport into cytosol GO:0010523 4 0.014
negative regulation of ion transport GO:0043271 51 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
sexual reproduction GO:0019953 148 0.014
cellular protein localization GO:0034613 122 0.014
regulation of sodium ion transport GO:0002028 21 0.014
cytoskeleton organization GO:0007010 111 0.014
regulation of homotypic cell cell adhesion GO:0034110 4 0.014
nucleoside metabolic process GO:0009116 179 0.014
nucleotide metabolic process GO:0009117 279 0.014
platelet aggregation GO:0070527 4 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
regulation of blood circulation GO:1903522 110 0.014
regulation of protein serine threonine kinase activity GO:0071900 64 0.014
regulation of synaptic transmission glutamatergic GO:0051966 26 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
regulation of endocytosis GO:0030100 42 0.014
positive regulation of kinase activity GO:0033674 77 0.014
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.014
regulation of muscle tissue development GO:1901861 25 0.014
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.014
regulation of vasoconstriction GO:0019229 44 0.014
mesonephros development GO:0001823 14 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
response to purine containing compound GO:0014074 126 0.013
positive regulation of fat cell proliferation GO:0070346 1 0.013
regulation of peptide transport GO:0090087 87 0.013
telencephalon development GO:0021537 62 0.013
cgmp biosynthetic process GO:0006182 15 0.013
multicellular organism reproduction GO:0032504 233 0.013
regulation of cellular component size GO:0032535 51 0.013
single organism organelle organization GO:1902589 180 0.013
response to increased oxygen levels GO:0036296 45 0.013
carbohydrate catabolic process GO:0016052 40 0.013
regulation of neuron death GO:1901214 115 0.013

Otx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
retinal disease DOID:5679 0 0.042
sensory system disease DOID:0050155 0 0.042
eye and adnexa disease DOID:1492 0 0.042
eye disease DOID:5614 0 0.042
musculoskeletal system disease DOID:17 0 0.039
connective tissue disease DOID:65 0 0.029
retinal degeneration DOID:8466 0 0.015