Rattus norvegicus

178 known processes

P2rx7

purinergic receptor P2X, ligand-gated ion channel, 7

P2rx7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
homeostatic process GO:0042592 331 0.401
Human Mouse
amino acid transport GO:0006865 70 0.354
Mouse
transmembrane transport GO:0055085 412 0.192
response to other organism GO:0051707 220 0.184
Mouse
regulation of signal transduction GO:0009966 318 0.183
Mouse
anion transport GO:0006820 178 0.175
Mouse
regeneration GO:0031099 163 0.174
Rat
response to heat GO:0009408 60 0.147
response to wounding GO:0009611 254 0.141
Rat
purine ribonucleotide catabolic process GO:0009154 136 0.137
positive regulation of response to stimulus GO:0048584 285 0.130
Mouse
cell cell signaling GO:0007267 335 0.127
Mouse Rat
cellular response to endogenous stimulus GO:0071495 377 0.126
cellular component assembly GO:0022607 360 0.125
regulation of organelle organization GO:0033043 80 0.122
regulation of phosphorus metabolic process GO:0051174 349 0.121
response to cytokine GO:0034097 215 0.119
response to external biotic stimulus GO:0043207 221 0.113
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.109
protein complex subunit organization GO:0071822 302 0.108
cation transport GO:0006812 382 0.107
oligopeptide transport GO:0006857 4 0.098
regulation of cellular localization GO:0060341 263 0.097
tissue regeneration GO:0042246 36 0.097
Rat
cell projection organization GO:0030030 302 0.093
organic acid transport GO:0015849 116 0.092
Mouse
metal ion transport GO:0030001 289 0.089
intracellular transport GO:0046907 185 0.085
Human Mouse
monovalent inorganic cation transport GO:0015672 172 0.085
nucleic acid templated transcription GO:0097659 379 0.084
immune response GO:0006955 104 0.084
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.083
ion transmembrane transport GO:0034220 365 0.083
carboxylic acid transport GO:0046942 115 0.082
Mouse
purine nucleotide metabolic process GO:0006163 229 0.081
response to decreased oxygen levels GO:0036293 237 0.080
central nervous system development GO:0007417 311 0.078
regulation of protein metabolic process GO:0051246 289 0.077
regulation of catalytic activity GO:0050790 304 0.076
nucleoside phosphate metabolic process GO:0006753 283 0.076
nucleotide catabolic process GO:0009166 139 0.076
macrophage chemotaxis GO:0048246 2 0.074
protein complex biogenesis GO:0070271 263 0.072
immune system process GO:0002376 204 0.072
Mouse
protein oligomerization GO:0051259 191 0.072
Mouse Rat
positive regulation of programmed cell death GO:0043068 157 0.071
Mouse
regulation of molecular function GO:0065009 398 0.071
carbohydrate derivative metabolic process GO:1901135 346 0.071
transcription dna templated GO:0006351 377 0.071
single organism organelle organization GO:1902589 180 0.070
response to tumor necrosis factor GO:0034612 56 0.069
negative regulation of metabolic process GO:0009892 331 0.068
Mouse
regulation of cell differentiation GO:0045595 320 0.064
aromatic compound catabolic process GO:0019439 168 0.063
regulation of multicellular organismal development GO:2000026 376 0.062
Mouse Rat
single organism membrane organization GO:0044802 74 0.062
Mouse
positive regulation of cellular protein metabolic process GO:0032270 167 0.061
response to corticosteroid GO:0031960 235 0.061
response to inorganic substance GO:0010035 377 0.059
Mouse
positive regulation of cell communication GO:0010647 271 0.058
Mouse
macromolecular complex assembly GO:0065003 273 0.058
organelle organization GO:0006996 266 0.058
regulation of membrane potential GO:0042391 110 0.058
brain development GO:0007420 247 0.057
positive regulation of cell development GO:0010720 176 0.057
regulation of phosphorylation GO:0042325 248 0.056
regulation of immune system process GO:0002682 123 0.056
Mouse
apoptotic process GO:0006915 381 0.056
nucleobase containing small molecule metabolic process GO:0055086 316 0.056
response to blue light GO:0009637 1 0.054
hormone transport GO:0009914 121 0.053
cation transmembrane transport GO:0098655 263 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.052
regulation of apoptotic process GO:0042981 335 0.051
Mouse
macromolecule localization GO:0033036 252 0.051
ribose phosphate metabolic process GO:0019693 235 0.051
regulation of rna metabolic process GO:0051252 391 0.050
rna metabolic process GO:0016070 406 0.050
response to toxic substance GO:0009636 133 0.050
macromolecular complex subunit organization GO:0043933 339 0.050
protein complex assembly GO:0006461 263 0.049
chemical homeostasis GO:0048878 292 0.049
Human Mouse
purine containing compound catabolic process GO:0072523 138 0.049
organic substance catabolic process GO:1901575 316 0.049
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.048
neurological system process GO:0050877 219 0.048
lipid metabolic process GO:0006629 283 0.048
Mouse
cellular homeostasis GO:0019725 252 0.048
Human Mouse
cellular ion homeostasis GO:0006873 184 0.047
Human Mouse
negative regulation of cell communication GO:0010648 158 0.047
Mouse
amide transport GO:0042886 105 0.047
heart contraction GO:0060047 57 0.047
antibiotic transport GO:0042891 2 0.046
protein homooligomerization GO:0051260 91 0.046
Rat
cardiovascular system development GO:0072358 134 0.046
single organism reproductive process GO:0044702 297 0.045
organophosphate metabolic process GO:0019637 370 0.045
organic anion transport GO:0015711 132 0.045
Mouse
positive regulation of cell death GO:0010942 184 0.045
reproductive process GO:0022414 372 0.045
regulation of transcription dna templated GO:0006355 374 0.045
regulation of immune response GO:0050776 55 0.044
Mouse
organic cyclic compound catabolic process GO:1901361 175 0.044
regulation of anatomical structure size GO:0090066 135 0.044
Rat
regulation of cellular component organization GO:0051128 368 0.043
ribonucleotide catabolic process GO:0009261 136 0.043
nucleotide metabolic process GO:0009117 279 0.043
tissue development GO:0009888 252 0.043
Mouse Rat
skeletal muscle tissue regeneration GO:0043403 10 0.043
Rat
positive regulation of locomotion GO:0040017 102 0.043
nucleoside triphosphate metabolic process GO:0009141 144 0.043
single organism intracellular transport GO:1902582 166 0.043
Human Mouse
response to peptide GO:1901652 292 0.043
regulation of secretion by cell GO:1903530 208 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
sensory perception GO:0007600 101 0.042
Mouse Rat
drug transmembrane transport GO:0006855 13 0.042
purine nucleoside triphosphate catabolic process GO:0009146 122 0.042
positive regulation of nervous system development GO:0051962 178 0.042
organonitrogen compound biosynthetic process GO:1901566 167 0.042
Mouse
developmental process involved in reproduction GO:0003006 159 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
regulation of intracellular signal transduction GO:1902531 218 0.041
Mouse
prostaglandin transport GO:0015732 8 0.041
Mouse
regulation of catabolic process GO:0009894 113 0.040
response to extracellular stimulus GO:0009991 380 0.040
Mouse
protein transport GO:0015031 132 0.040
gliogenesis GO:0042063 93 0.039
neuron projection development GO:0031175 273 0.039
cell part morphogenesis GO:0032990 123 0.039
positive regulation of cell differentiation GO:0045597 217 0.039
ribonucleotide metabolic process GO:0009259 231 0.039
neuron development GO:0048666 286 0.039
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.038
neuron differentiation GO:0030182 368 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
Mouse
rna biosynthetic process GO:0032774 380 0.038
secretion GO:0046903 307 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
positive regulation of cellular component organization GO:0051130 200 0.037
purine nucleoside catabolic process GO:0006152 124 0.037
negative regulation of signal transduction GO:0009968 83 0.036
Mouse
purine containing compound metabolic process GO:0072521 253 0.036
positive regulation of secretion GO:0051047 140 0.036
ribonucleoside triphosphate catabolic process GO:0009203 122 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.035
anion transmembrane transport GO:0098656 77 0.035
purine nucleoside metabolic process GO:0042278 169 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
protein localization GO:0008104 191 0.035
cellular response to tumor necrosis factor GO:0071356 46 0.034
cellular component morphogenesis GO:0032989 155 0.034
Mouse
protein phosphorylation GO:0006468 345 0.034
reproductive system development GO:0061458 128 0.034
response to purine containing compound GO:0014074 126 0.034
positive regulation of transport GO:0051050 245 0.033
negative regulation of signaling GO:0023057 157 0.033
Mouse
catabolic process GO:0009056 351 0.033
Mouse
regulation of protein phosphorylation GO:0001932 183 0.033
multi multicellular organism process GO:0044706 138 0.033
nucleoside triphosphate catabolic process GO:0009143 123 0.033
regulation of kinase activity GO:0043549 117 0.033
positive regulation of developmental process GO:0051094 283 0.032
Mouse
growth GO:0040007 165 0.032
Rat
glycosyl compound metabolic process GO:1901657 182 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
mesoderm development GO:0007498 2 0.032
ion homeostasis GO:0050801 212 0.031
Human Mouse
regulation of protein localization GO:0032880 81 0.031
intracellular signal transduction GO:0035556 314 0.031
Mouse
localization of cell GO:0051674 202 0.031
negative regulation of protein metabolic process GO:0051248 114 0.031
reproduction GO:0000003 245 0.031
regulation of hydrolase activity GO:0051336 143 0.031
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.030
protein processing GO:0016485 68 0.030
Mouse
positive regulation of phosphorylation GO:0042327 177 0.030
nucleoside catabolic process GO:0009164 126 0.030
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.030
carbohydrate derivative catabolic process GO:1901136 147 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
muscle system process GO:0003012 115 0.030
cellular chemical homeostasis GO:0055082 247 0.030
Human Mouse
cellular component biogenesis GO:0044085 368 0.029
urogenital system development GO:0001655 78 0.029
cellular protein localization GO:0034613 122 0.029
peptide transport GO:0015833 97 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
positive regulation of secretion by cell GO:1903532 128 0.029
regulation of programmed cell death GO:0043067 341 0.029
Mouse
regulation of ion transport GO:0043269 245 0.029
nucleoside phosphate catabolic process GO:1901292 140 0.028
response to glucose GO:0009749 136 0.028
negative regulation of chronic inflammatory response GO:0002677 2 0.028
multicellular organism reproduction GO:0032504 233 0.028
response to hypoxia GO:0001666 231 0.028
response to metal ion GO:0010038 253 0.028
Mouse
regulation of neuron differentiation GO:0045664 208 0.028
locomotion GO:0040011 237 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
negative regulation of cell proliferation GO:0008285 119 0.028
neuronal action potential GO:0019228 35 0.028
purine nucleotide catabolic process GO:0006195 136 0.028
nitrogen compound transport GO:0071705 229 0.027
Mouse
negative regulation of gene expression GO:0010629 199 0.027
response to bacterium GO:0009617 200 0.027
Mouse
renal system development GO:0072001 67 0.027
positive regulation of signaling GO:0023056 270 0.027
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.026
Mouse
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of response to stress GO:0080134 126 0.026
Rat
response to acid chemical GO:0001101 222 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
response to nutrient levels GO:0031667 370 0.026
ras protein signal transduction GO:0007265 29 0.026
inflammatory response GO:0006954 150 0.026
Mouse
cellular response to cytokine stimulus GO:0071345 127 0.025
negative regulation of long term synaptic potentiation GO:1900272 1 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
regulation of system process GO:0044057 208 0.025
dicarboxylic acid transport GO:0006835 34 0.025
Mouse
mapk cascade GO:0000165 140 0.025
Mouse
nucleoside metabolic process GO:0009116 179 0.025
protein maturation GO:0051604 68 0.025
Mouse
positive regulation of signal transduction GO:0009967 175 0.024
Mouse
kidney development GO:0001822 67 0.024
glutathione transport GO:0034635 2 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
cellular macromolecule localization GO:0070727 122 0.024
glycosyl compound catabolic process GO:1901658 126 0.024
regulation of cell proliferation GO:0042127 359 0.024
neuron projection morphogenesis GO:0048812 122 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
response to oxygen levels GO:0070482 265 0.023
response to reactive oxygen species GO:0000302 120 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
defense response GO:0006952 194 0.023
Mouse
positive regulation of cell proliferation GO:0008284 249 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
response to biotic stimulus GO:0009607 226 0.023
Mouse
synaptic transmission GO:0007268 235 0.022
Mouse Rat
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.022
heterocycle catabolic process GO:0046700 167 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
gamete generation GO:0007276 124 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
regulation of secretion GO:0051046 224 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
inorganic cation transmembrane transport GO:0098662 202 0.021
response to monosaccharide GO:0034284 159 0.021
reproductive structure development GO:0048608 128 0.021
interleukin 1 beta secretion GO:0050702 3 0.021
positive regulation of protein modification process GO:0031401 142 0.021
striated muscle contraction GO:0006941 44 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
response to glucocorticoid GO:0051384 223 0.021
single organism behavior GO:0044708 130 0.021
vesicle mediated transport GO:0016192 181 0.021
Mouse
negative regulation of apoptotic process GO:0043066 181 0.021
bmp signaling pathway GO:0030509 4 0.021
organophosphate catabolic process GO:0046434 148 0.020
salivary gland development GO:0007431 3 0.020
monocarboxylic acid transport GO:0015718 52 0.020
Mouse
cellular component movement GO:0006928 248 0.020
response to carbohydrate GO:0009743 183 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
oxoacid metabolic process GO:0043436 290 0.020
cellular catabolic process GO:0044248 295 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
cellular response to stress GO:0033554 269 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
cell morphogenesis GO:0000902 142 0.020
Mouse
cellular amino acid metabolic process GO:0006520 107 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
Mouse
cellular ketone metabolic process GO:0042180 51 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
cell projection morphogenesis GO:0048858 123 0.019
amine metabolic process GO:0009308 38 0.019
positive regulation of immune response GO:0050778 42 0.019
Mouse
positive regulation of neuron projection development GO:0010976 99 0.019
regulation of peptide transport GO:0090087 87 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
ribonucleoside metabolic process GO:0009119 174 0.018
sensory perception of pain GO:0019233 73 0.018
Mouse Rat
response to ketone GO:1901654 182 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
cellular amine metabolic process GO:0044106 38 0.018
single organism catabolic process GO:0044712 283 0.018
Mouse
regulation of cell development GO:0060284 263 0.018
organ regeneration GO:0031100 101 0.018
negative regulation of transcription dna templated GO:0045892 116 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
cellular lipid metabolic process GO:0044255 208 0.018
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
positive regulation of catalytic activity GO:0043085 184 0.017
spermatogenesis GO:0007283 99 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
modified amino acid transport GO:0072337 12 0.017
regulation of mapk cascade GO:0043408 116 0.017
Mouse
positive regulation of cellular component movement GO:0051272 102 0.017
response to antibiotic GO:0046677 39 0.017
regulation of growth GO:0040008 105 0.017
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.017
Mouse
positive regulation of molecular function GO:0044093 230 0.017
regulation of cell projection organization GO:0031344 175 0.017
negative regulation of cell death GO:0060548 229 0.017
regulation of nervous system development GO:0051960 264 0.017
neurotransmitter transport GO:0006836 42 0.017
Mouse
defense response to gram negative bacterium GO:0050829 3 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
complement receptor mediated signaling pathway GO:0002430 2 0.017
purine nucleoside monophosphate metabolic process GO:0009126 84 0.017
heart process GO:0003015 57 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
response to hexose GO:0009746 144 0.016
regulation of neuron projection development GO:0010975 161 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
Mouse
regulation of cytokine production GO:0001817 56 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
Mouse
gastrulation GO:0007369 2 0.016
cell motility GO:0048870 202 0.016
muscle contraction GO:0006936 88 0.016
proteolysis GO:0006508 175 0.016
Mouse
cation homeostasis GO:0055080 195 0.016
Human Mouse
regulation of response to external stimulus GO:0032101 106 0.016
Rat
response to organophosphorus GO:0046683 102 0.016
anterior posterior pattern specification GO:0009952 1 0.016
cellular response to glucocorticoid stimulus GO:0071385 68 0.016
wound healing GO:0042060 122 0.015
Rat
purine nucleoside monophosphate catabolic process GO:0009128 55 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
potassium ion transmembrane transport GO:0071805 71 0.015
protein heterooligomerization GO:0051291 89 0.015
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
heart morphogenesis GO:0003007 3 0.015
response to oxidative stress GO:0006979 186 0.015
cytoplasmic transport GO:0016482 115 0.015
Human Mouse
lipid biosynthetic process GO:0008610 128 0.015
Mouse
regulation of nucleotide catabolic process GO:0030811 65 0.014
membrane organization GO:0061024 94 0.014
Mouse
regulation of response to wounding GO:1903034 69 0.014
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
endomembrane system organization GO:0010256 48 0.014
Mouse
l glutamate import GO:0051938 2 0.014
multicellular organism growth GO:0035264 1 0.014
regulation of peptide secretion GO:0002791 82 0.014
response to peptide hormone GO:0043434 278 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
multi organism reproductive process GO:0044703 262 0.014
eye morphogenesis GO:0048592 4 0.014
drug transport GO:0015893 18 0.014
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.013
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
angiogenesis GO:0001525 53 0.013
regulation of interleukin 1 production GO:0032652 11 0.013
organic acid metabolic process GO:0006082 292 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
gtp metabolic process GO:0046039 72 0.013
immune effector process GO:0002252 53 0.013
Mouse
negative regulation of phosphate metabolic process GO:0045936 80 0.013
Mouse
response to alkaloid GO:0043279 132 0.013
lipid transport GO:0006869 61 0.013
Mouse
response to nicotine GO:0035094 51 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
regulation of transferase activity GO:0051338 123 0.013
sequestering of calcium ion GO:0051208 8 0.013
Mouse
hormone secretion GO:0046879 115 0.013
response to molecule of fungal origin GO:0002238 3 0.013
stem cell maintenance GO:0019827 6 0.013
positive regulation of immune system process GO:0002684 90 0.013
Mouse
protein targeting GO:0006605 61 0.013
signal release GO:0023061 145 0.013
Mouse
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
actin filament based process GO:0030029 86 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
regulation of neurogenesis GO:0050767 247 0.012
axis specification GO:0009798 4 0.012
male gamete generation GO:0048232 99 0.012
cellular response to oxygen levels GO:0071453 60 0.012
cytolysis GO:0019835 4 0.012
secretion by cell GO:0032940 248 0.012
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.012
regulation of defense response GO:0031347 68 0.012
positive regulation of organelle organization GO:0010638 48 0.012
response to growth factor GO:0070848 189 0.012
negative regulation of transport GO:0051051 136 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
blood circulation GO:0008015 183 0.012
Rat
small molecule biosynthetic process GO:0044283 124 0.012
tripeptide transport GO:0042939 2 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
tolerance induction dependent upon immune response GO:0002461 2 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
regulation of protein processing GO:0070613 50 0.012
regulation of locomotion GO:0040012 148 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
negative regulation of protein processing GO:0010955 47 0.012
toxin transport GO:1901998 3 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of protein kinase activity GO:0045859 105 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
choline transport GO:0015871 4 0.012
regulation of blood vessel size GO:0050880 89 0.012
Rat
regulation of synaptic transmission GO:0050804 141 0.011
negative regulation of molecular function GO:0044092 133 0.011
defense response to other organism GO:0098542 17 0.011
Mouse
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 1 0.011
sex differentiation GO:0007548 113 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
sodium independent organic anion transport GO:0043252 2 0.011
response to temperature stimulus GO:0009266 94 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
positive regulation of intracellular transport GO:0032388 39 0.011
Human
response to estrogen GO:0043627 232 0.011
regulation of tube size GO:0035150 89 0.011
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
Human Mouse
head development GO:0060322 247 0.011
positive regulation of cell migration GO:0030335 96 0.011
negative regulation of immune system process GO:0002683 39 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
positive regulation of cell motility GO:2000147 97 0.011
response to dexamethasone GO:0071548 49 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
fibrinolysis GO:0042730 2 0.011
glial cell differentiation GO:0010001 65 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
Mouse
calcium ion homeostasis GO:0055074 162 0.011
Human Mouse
inner ear morphogenesis GO:0042472 1 0.011
peptidyl amino acid modification GO:0018193 126 0.011
regulation of protein maturation GO:1903317 50 0.011
acidic amino acid transport GO:0015800 10 0.011
organ formation GO:0048645 3 0.011
regulation of intracellular transport GO:0032386 65 0.011
Human
regulation of hormone secretion GO:0046883 106 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
cell type specific apoptotic process GO:0097285 134 0.011
Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.011
negative regulation of luteinizing hormone secretion GO:0033685 4 0.011
regulation of sensory perception GO:0051931 29 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
forebrain development GO:0030900 98 0.011
negative regulation of protein maturation GO:1903318 47 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010
positive regulation of synaptic transmission GO:0050806 62 0.010
glucose homeostasis GO:0042593 75 0.010
response to ph GO:0009268 27 0.010
cellular cation homeostasis GO:0030003 180 0.010
Human Mouse
aging GO:0007568 241 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
fertilization GO:0009566 3 0.010
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
regulation of sensory perception of pain GO:0051930 29 0.010
angioblast cell migration GO:0035476 1 0.010

P2rx7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
nervous system disease DOID:863 0 0.066
cardiovascular system disease DOID:1287 0 0.040
disease of metabolism DOID:0014667 0 0.028
musculoskeletal system disease DOID:17 0 0.025
sensory system disease DOID:0050155 0 0.014
obesity DOID:9970 0 0.013
nutrition disease DOID:374 0 0.013
overnutrition DOID:654 0 0.013
acquired metabolic disease DOID:0060158 0 0.013
inherited metabolic disorder DOID:655 0 0.010