Rattus norvegicus

129 known processes

Pafah1b1

platelet-activating factor acetylhydrolase, isoform 1b, subunit 1

(Aliases: LIS1)

Pafah1b1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly GO:0022607 360 0.203
Mouse Worm Fly
protein complex biogenesis GO:0070271 263 0.184
Worm Fly
intracellular signal transduction GO:0035556 314 0.116
Mouse
establishment of protein localization GO:0045184 141 0.112
Mouse Fly
regulation of molecular function GO:0065009 398 0.109
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.101
Mouse
regulation of cellular component organization GO:0051128 368 0.095
secretion GO:0046903 307 0.093
Mouse
cellular component biogenesis GO:0044085 368 0.093
Mouse Worm Fly
cation transport GO:0006812 382 0.089
intracellular transport GO:0046907 185 0.087
Mouse Fly
regulation of phosphate metabolic process GO:0019220 349 0.084
Mouse
macromolecular complex assembly GO:0065003 273 0.083
Worm Fly
protein complex assembly GO:0006461 263 0.079
Worm Fly
organophosphate catabolic process GO:0046434 148 0.077
Mouse
intracellular protein transport GO:0006886 79 0.077
Fly
organelle organization GO:0006996 266 0.075
Human Mouse Worm Fly
organic substance catabolic process GO:1901575 316 0.075
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.071
single organism intracellular transport GO:1902582 166 0.071
Mouse Fly
catabolic process GO:0009056 351 0.070
Mouse
single organism cellular localization GO:1902580 102 0.070
Human Mouse Worm Fly
transmembrane transport GO:0055085 412 0.069
macromolecule localization GO:0033036 252 0.069
Zebrafish Mouse Fly
macromolecular complex subunit organization GO:0043933 339 0.067
Worm Fly
regulation of cellular localization GO:0060341 263 0.066
Fly
regulation of neuron projection development GO:0010975 161 0.066
vesicle mediated transport GO:0016192 181 0.065
Worm
purine nucleoside metabolic process GO:0042278 169 0.064
Mouse
anatomical structure morphogenesis GO:0009653 298 0.063
organonitrogen compound biosynthetic process GO:1901566 167 0.062
protein targeting GO:0006605 61 0.061
protein transport GO:0015031 132 0.060
Mouse Fly
response to cytokine GO:0034097 215 0.057
Mouse
positive regulation of cellular component organization GO:0051130 200 0.057
response to oxygen levels GO:0070482 265 0.056
nucleobase containing small molecule metabolic process GO:0055086 316 0.056
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.055
Mouse
response to inorganic substance GO:0010035 377 0.055
cellular response to oxygen containing compound GO:1901701 386 0.053
cellular response to peptide hormone stimulus GO:0071375 120 0.052
cellular component morphogenesis GO:0032989 155 0.052
cellular macromolecule localization GO:0070727 122 0.051
Fly
cell motility GO:0048870 202 0.051
positive regulation of cellular protein metabolic process GO:0032270 167 0.051
regulation of secretion GO:0051046 224 0.050
negative regulation of transport GO:0051051 136 0.050
nitrogen compound transport GO:0071705 229 0.049
response to nutrient levels GO:0031667 370 0.048
regulation of anatomical structure morphogenesis GO:0022603 141 0.048
cytoplasmic transport GO:0016482 115 0.048
Fly
protein complex subunit organization GO:0071822 302 0.048
Worm Fly
regulation of multicellular organismal development GO:2000026 376 0.047
positive regulation of gene expression GO:0010628 244 0.047
cell projection morphogenesis GO:0048858 123 0.047
cell projection organization GO:0030030 302 0.045
protein oligomerization GO:0051259 191 0.045
secretion by cell GO:0032940 248 0.045
Mouse
apoptotic process GO:0006915 381 0.044
positive regulation of transport GO:0051050 245 0.044
Fly
neuron development GO:0048666 286 0.044
regulation of protein metabolic process GO:0051246 289 0.044
Fly
regulation of protein modification process GO:0031399 194 0.043
organophosphate metabolic process GO:0019637 370 0.043
Mouse
protein localization GO:0008104 191 0.042
Zebrafish Mouse Fly
carbohydrate derivative catabolic process GO:1901136 147 0.042
Mouse
nucleoside metabolic process GO:0009116 179 0.042
Mouse
regulation of neurogenesis GO:0050767 247 0.041
purine containing compound metabolic process GO:0072521 253 0.041
Mouse
regulation of cell morphogenesis GO:0022604 77 0.040
cellular response to nitrogen compound GO:1901699 210 0.040
regulation of ion transport GO:0043269 245 0.040
cellular response to endogenous stimulus GO:0071495 377 0.039
neurological system process GO:0050877 219 0.038
Human Mouse
regulation of protein phosphorylation GO:0001932 183 0.038
purine nucleoside catabolic process GO:0006152 124 0.038
Mouse
nucleoside triphosphate catabolic process GO:0009143 123 0.038
Mouse
cell morphogenesis GO:0000902 142 0.037
regulation of signal transduction GO:0009966 318 0.037
Mouse Fly
organonitrogen compound catabolic process GO:1901565 179 0.036
Mouse
cellular response to peptide GO:1901653 133 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.035
Mouse
regulation of secretion by cell GO:1903530 208 0.035
response to hypoxia GO:0001666 231 0.035
purine nucleotide metabolic process GO:0006163 229 0.035
Mouse
metal ion transport GO:0030001 289 0.035
circulatory system development GO:0072359 134 0.035
programmed cell death GO:0012501 392 0.035
cellular protein localization GO:0034613 122 0.034
Fly
purine ribonucleoside catabolic process GO:0046130 124 0.034
Mouse
cellular catabolic process GO:0044248 295 0.034
Mouse
response to peptide GO:1901652 292 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
response to metal ion GO:0010038 253 0.033
regulation of catalytic activity GO:0050790 304 0.032
Mouse
single organism catabolic process GO:0044712 283 0.032
Mouse
proteolysis GO:0006508 175 0.031
amine metabolic process GO:0009308 38 0.031
response to extracellular stimulus GO:0009991 380 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
regulation of apoptotic process GO:0042981 335 0.031
single organism biosynthetic process GO:0044711 342 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
alpha amino acid metabolic process GO:1901605 71 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
Mouse
organic cyclic compound catabolic process GO:1901361 175 0.030
Mouse
cellular chemical homeostasis GO:0055082 247 0.029
growth GO:0040007 165 0.029
ribonucleotide metabolic process GO:0009259 231 0.029
Mouse
purine containing compound catabolic process GO:0072523 138 0.029
Mouse
neuron projection morphogenesis GO:0048812 122 0.029
glycosyl compound metabolic process GO:1901657 182 0.029
Mouse
response to peptide hormone GO:0043434 278 0.028
response to nutrient GO:0007584 248 0.028
response to hexose GO:0009746 144 0.028
cellular response to hormone stimulus GO:0032870 247 0.028
cellular amine metabolic process GO:0044106 38 0.028
regulation of axonogenesis GO:0050770 37 0.028
rna biosynthetic process GO:0032774 380 0.027
protein phosphorylation GO:0006468 345 0.027
single organism organelle organization GO:1902589 180 0.027
Human Mouse Worm Fly
response to decreased oxygen levels GO:0036293 237 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
organic acid metabolic process GO:0006082 292 0.027
response to corticosteroid GO:0031960 235 0.027
gastrulation GO:0007369 2 0.027
cellular response to stress GO:0033554 269 0.026
Mouse
actin filament based process GO:0030029 86 0.026
Mouse
response to insulin GO:0032868 133 0.026
bmp signaling pathway GO:0030509 4 0.026
Fly
ras protein signal transduction GO:0007265 29 0.026
establishment of protein localization to organelle GO:0072594 44 0.026
response to monosaccharide GO:0034284 159 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
regulation of vesicle mediated transport GO:0060627 81 0.025
regulation of system process GO:0044057 208 0.025
oxoacid metabolic process GO:0043436 290 0.025
aromatic compound catabolic process GO:0019439 168 0.025
Mouse
regulation of cell projection organization GO:0031344 175 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cation transmembrane transport GO:0098655 263 0.025
regulation of phosphorylation GO:0042325 248 0.024
Mouse
positive regulation of protein modification process GO:0031401 142 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
ion transmembrane transport GO:0034220 365 0.024
negative regulation of molecular function GO:0044092 133 0.024
ribose phosphate metabolic process GO:0019693 235 0.023
Mouse
gtp metabolic process GO:0046039 72 0.023
Mouse
small gtpase mediated signal transduction GO:0007264 36 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
actin cytoskeleton organization GO:0030036 73 0.023
Mouse
nucleic acid templated transcription GO:0097659 379 0.023
transcription dna templated GO:0006351 377 0.023
regulation of cell development GO:0060284 263 0.023
regulation of response to stress GO:0080134 126 0.022
Mouse
membrane organization GO:0061024 94 0.022
Mouse Worm
positive regulation of molecular function GO:0044093 230 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
Fly
synaptic transmission GO:0007268 235 0.022
Mouse Worm
response to external biotic stimulus GO:0043207 221 0.022
aging GO:0007568 241 0.022
mesoderm development GO:0007498 2 0.021
protein localization to organelle GO:0033365 57 0.021
Fly
cell cycle GO:0007049 101 0.021
response to carbohydrate GO:0009743 183 0.021
neuron differentiation GO:0030182 368 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
Fly
coenzyme metabolic process GO:0006732 86 0.020
regulation of hormone levels GO:0010817 187 0.020
positive regulation of developmental process GO:0051094 283 0.020
positive regulation of secretion by cell GO:1903532 128 0.020
negative regulation of cellular component organization GO:0051129 83 0.019
regulation of cell differentiation GO:0045595 320 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
Mouse
heterocycle catabolic process GO:0046700 167 0.019
Mouse
cell migration GO:0016477 197 0.018
chemical homeostasis GO:0048878 292 0.018
positive regulation of cell development GO:0010720 176 0.018
mitotic spindle organization GO:0007052 2 0.018
Worm
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
Mouse Fly
cofactor metabolic process GO:0051186 95 0.018
nucleotide metabolic process GO:0009117 279 0.018
Mouse
inorganic ion transmembrane transport GO:0098660 229 0.018
response to lipopolysaccharide GO:0032496 191 0.018
cell morphogenesis involved in differentiation GO:0000904 119 0.018
mapk cascade GO:0000165 140 0.018
Mouse
response to oxidative stress GO:0006979 186 0.018
response to other organism GO:0051707 220 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
muscle system process GO:0003012 115 0.018
blood circulation GO:0008015 183 0.018
response to biotic stimulus GO:0009607 226 0.018
response to glucocorticoid GO:0051384 223 0.018
positive regulation of neuron differentiation GO:0045666 126 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
Mouse
cellular homeostasis GO:0019725 252 0.017
Fly
regulation of hydrolase activity GO:0051336 143 0.017
Mouse
positive regulation of cell death GO:0010942 184 0.017
hormone secretion GO:0046879 115 0.017
cell part morphogenesis GO:0032990 123 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
Mouse
positive regulation of catalytic activity GO:0043085 184 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
Mouse
negative regulation of cell death GO:0060548 229 0.017
signal release GO:0023061 145 0.017
regulation of neuron differentiation GO:0045664 208 0.017
defense response GO:0006952 194 0.016
response to growth factor GO:0070848 189 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.016
neuron projection development GO:0031175 273 0.016
cellular component movement GO:0006928 248 0.016
neuron death GO:0070997 127 0.016
mitochondrial transport GO:0006839 19 0.016
embryonic pattern specification GO:0009880 1 0.016
regulation of kinase activity GO:0043549 117 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
Mouse
metal ion homeostasis GO:0055065 186 0.016
cell cell signaling GO:0007267 335 0.016
Mouse Worm
nucleotide catabolic process GO:0009166 139 0.016
Mouse
purine nucleotide catabolic process GO:0006195 136 0.016
Mouse
inorganic cation transmembrane transport GO:0098662 202 0.016
regulation of transcription dna templated GO:0006355 374 0.015
Fly
small molecule biosynthetic process GO:0044283 124 0.015
regulation of membrane potential GO:0042391 110 0.015
regulation of bmp signaling pathway GO:0030510 2 0.015
Fly
negative regulation of apoptotic process GO:0043066 181 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
regulation of nervous system development GO:0051960 264 0.015
ion homeostasis GO:0050801 212 0.015
protein modification by small protein conjugation GO:0032446 31 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
Mouse
positive regulation of secretion GO:0051047 140 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
Mouse
response to acid chemical GO:0001101 222 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
Mouse
positive regulation of cell communication GO:0010647 271 0.015
Mouse
spindle organization GO:0007051 2 0.015
Worm Fly
organic hydroxy compound metabolic process GO:1901615 115 0.015
head development GO:0060322 247 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
Mouse
learning or memory GO:0007611 90 0.015
Mouse
response to glucose GO:0009749 136 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.014
Mouse
negative regulation of metabolic process GO:0009892 331 0.014
Mouse
negative regulation of cell communication GO:0010648 158 0.014
Mouse
protein import GO:0017038 37 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
positive regulation of signaling GO:0023056 270 0.014
Mouse
regulation of programmed cell death GO:0043067 341 0.014
calcium ion transport GO:0006816 131 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
response to bacterium GO:0009617 200 0.014
chemosensory behavior GO:0007635 2 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
membrane fusion GO:0061025 26 0.014
anterior posterior pattern specification GO:0009952 1 0.014
regulation of protein kinase activity GO:0045859 105 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
cellular cation homeostasis GO:0030003 180 0.014
positive regulation of transferase activity GO:0051347 81 0.014
negative regulation of cell development GO:0010721 82 0.013
protein homooligomerization GO:0051260 91 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
Mouse
regulation of locomotion GO:0040012 148 0.013
regulation of cell motility GO:2000145 131 0.013
amide transport GO:0042886 105 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
Mouse
nucleocytoplasmic transport GO:0006913 48 0.013
regulation of transferase activity GO:0051338 123 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
single organism membrane organization GO:0044802 74 0.013
Mouse
regulation of protein localization GO:0032880 81 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
Mouse
regulation of peptide transport GO:0090087 87 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
cation homeostasis GO:0055080 195 0.013
lipid metabolic process GO:0006629 283 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
Mouse
negative regulation of response to stimulus GO:0048585 155 0.013
Mouse
negative regulation of signaling GO:0023057 157 0.013
Mouse
cellular response to cytokine stimulus GO:0071345 127 0.013
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.013
alcohol metabolic process GO:0006066 77 0.013
negative regulation of developmental process GO:0051093 125 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
regulation of protein import into nucleus GO:0042306 24 0.013
nucleoside catabolic process GO:0009164 126 0.013
Mouse
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
Mouse
negative regulation of cell differentiation GO:0045596 99 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
regulation of gtpase activity GO:0043087 57 0.012
Mouse
regulation of rna metabolic process GO:0051252 391 0.012
Fly
axis specification GO:0009798 4 0.012
Fly
tissue development GO:0009888 252 0.012
Fly
negative regulation of programmed cell death GO:0043069 183 0.012
behavior GO:0007610 205 0.012
Human Mouse
cellular response to growth factor stimulus GO:0071363 162 0.012
cell adhesion GO:0007155 110 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
localization of cell GO:0051674 202 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
Mouse
circulatory system process GO:0003013 183 0.012
homeostatic process GO:0042592 331 0.012
Zebrafish Fly
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
reproduction GO:0000003 245 0.012
Mouse Worm Fly
exocytosis GO:0006887 60 0.011
embryonic axis specification GO:0000578 1 0.011
muscle contraction GO:0006936 88 0.011
cellular protein complex assembly GO:0043623 44 0.011
rho protein signal transduction GO:0007266 11 0.011
cellular response to lipid GO:0071396 201 0.011
response to wounding GO:0009611 254 0.011
negative regulation of secretion GO:0051048 82 0.011
glycerolipid metabolic process GO:0046486 67 0.011
regulation of blood circulation GO:1903522 110 0.011
reproductive process GO:0022414 372 0.011
Mouse Worm Fly
negative regulation of nervous system development GO:0051961 79 0.011
positive regulation of catabolic process GO:0009896 78 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.011
Fly
regulation of rab protein signal transduction GO:0032483 3 0.011
endocytosis GO:0006897 84 0.011
Worm
positive regulation of cell differentiation GO:0045597 217 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.011
response to ethanol GO:0045471 162 0.011
cellular lipid metabolic process GO:0044255 208 0.011
rab protein signal transduction GO:0032482 1 0.011
positive regulation of signal transduction GO:0009967 175 0.011
Mouse
negative regulation of neuron projection development GO:0010977 46 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
cardiovascular system development GO:0072358 134 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
divalent metal ion transport GO:0070838 132 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
biological adhesion GO:0022610 110 0.011
liver development GO:0001889 90 0.011
regulation of organelle organization GO:0033043 80 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.010
regulation of metal ion transport GO:0010959 118 0.010
small molecule catabolic process GO:0044282 59 0.010
gtp catabolic process GO:0006184 71 0.010
Mouse
positive regulation of response to stimulus GO:0048584 285 0.010
Mouse
positive regulation of protein phosphorylation GO:0001934 135 0.010
cognition GO:0050890 92 0.010
Mouse
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
anion transport GO:0006820 178 0.010
locomotion GO:0040011 237 0.010
regulation of synaptic transmission GO:0050804 141 0.010
olfactory behavior GO:0042048 2 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
Fly
regulation of exocytosis GO:0017157 37 0.010
peptidyl amino acid modification GO:0018193 126 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
nucleoside monophosphate metabolic process GO:0009123 93 0.010
negative regulation of ion transport GO:0043271 51 0.010

Pafah1b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018