Rattus norvegicus

186 known processes

Parp1

poly (ADP-ribose) polymerase 1

(Aliases: MGC93658,Parp-1,Adprt)

Parp1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.476
rna metabolic process GO:0016070 406 0.426
rna biosynthetic process GO:0032774 380 0.335
transcription dna templated GO:0006351 377 0.284
oxoacid metabolic process GO:0043436 290 0.282
regulation of nucleic acid templated transcription GO:1903506 380 0.280
regulation of rna biosynthetic process GO:2001141 381 0.261
regulation of rna metabolic process GO:0051252 391 0.256
macromolecular complex subunit organization GO:0043933 339 0.247
nucleic acid templated transcription GO:0097659 379 0.246
transcription from rna polymerase ii promoter GO:0006366 252 0.220
regulation of multicellular organismal development GO:2000026 376 0.171
regulation of cellular component organization GO:0051128 368 0.162
organelle organization GO:0006996 266 0.153
Mouse
cellular amino acid metabolic process GO:0006520 107 0.142
organic acid metabolic process GO:0006082 292 0.137
macromolecular complex assembly GO:0065003 273 0.135
carboxylic acid metabolic process GO:0019752 289 0.119
negative regulation of rna biosynthetic process GO:1902679 118 0.112
chromosome organization GO:0051276 36 0.112
Mouse
regulation of programmed cell death GO:0043067 341 0.111
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.110
negative regulation of metabolic process GO:0009892 331 0.110
cellular response to stress GO:0033554 269 0.106
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.103
positive regulation of rna biosynthetic process GO:1902680 197 0.100
cellular component biogenesis GO:0044085 368 0.100
negative regulation of transcription dna templated GO:0045892 116 0.100
negative regulation of cellular metabolic process GO:0031324 281 0.098
regulation of protein metabolic process GO:0051246 289 0.096
negative regulation of cellular biosynthetic process GO:0031327 161 0.096
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.094
dna metabolic process GO:0006259 96 0.094
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 260 0.092
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.091
folic acid containing compound metabolic process GO:0006760 10 0.091
regulation of cell differentiation GO:0045595 320 0.089
central nervous system development GO:0007417 311 0.088
negative regulation of gene expression GO:0010629 199 0.088
positive regulation of rna metabolic process GO:0051254 203 0.087
programmed cell death GO:0012501 392 0.083
regulation of apoptotic process GO:0042981 335 0.082
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.079
regulation of cell development GO:0060284 263 0.078
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.077
apoptotic process GO:0006915 381 0.077
cellular response to organic cyclic compound GO:0071407 202 0.077
negative regulation of nucleic acid templated transcription GO:1903507 117 0.075
negative regulation of rna metabolic process GO:0051253 123 0.075
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.074
cellular component assembly GO:0022607 360 0.074
chromatin assembly or disassembly GO:0006333 1 0.073
histone h3 acetylation GO:0043966 2 0.071
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.069
cellular response to nitrogen compound GO:1901699 210 0.069
Human
regulation of cellular amine metabolic process GO:0033238 8 0.067
positive regulation of nucleic acid templated transcription GO:1903508 197 0.067
regulation of protein modification process GO:0031399 194 0.066
regulation of cellular ketone metabolic process GO:0010565 27 0.066
chromatin organization GO:0006325 34 0.065
positive regulation of transcription dna templated GO:0045893 197 0.065
positive regulation of cellular biosynthetic process GO:0031328 295 0.064
cellular response to organonitrogen compound GO:0071417 197 0.063
Human
positive regulation of gene expression GO:0010628 244 0.062
amine metabolic process GO:0009308 38 0.062
positive regulation of cellular component organization GO:0051130 200 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.061
cellular response to hormone stimulus GO:0032870 247 0.061
Human
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.061
response to hypoxia GO:0001666 231 0.061
peptidyl amino acid modification GO:0018193 126 0.060
negative regulation of biosynthetic process GO:0009890 168 0.060
protein phosphorylation GO:0006468 345 0.059
intracellular signal transduction GO:0035556 314 0.058
single organism reproductive process GO:0044702 297 0.058
cellular response to oxygen containing compound GO:1901701 386 0.058
Human Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.057
rhythmic process GO:0048511 156 0.057
response to nutrient levels GO:0031667 370 0.057
positive regulation of nervous system development GO:0051962 178 0.056
positive regulation of biosynthetic process GO:0009891 319 0.056
regulation of cellular amino acid metabolic process GO:0006521 2 0.056
positive regulation of protein metabolic process GO:0051247 178 0.056
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.055
positive regulation of cell differentiation GO:0045597 217 0.054
regulation of nervous system development GO:0051960 264 0.053
neuron differentiation GO:0030182 368 0.053
response to extracellular stimulus GO:0009991 380 0.053
response to peptide GO:1901652 292 0.053
Human
positive regulation of molecular function GO:0044093 230 0.053
regulation of molecular function GO:0065009 398 0.051
cellular response to oxidative stress GO:0034599 76 0.051
Mouse
neuron projection development GO:0031175 273 0.051
regulation of cellular localization GO:0060341 263 0.051
carbohydrate derivative metabolic process GO:1901135 346 0.050
protein complex subunit organization GO:0071822 302 0.049
single organism biosynthetic process GO:0044711 342 0.048
positive regulation of cell proliferation GO:0008284 249 0.048
anatomical structure morphogenesis GO:0009653 298 0.047
positive regulation of cell communication GO:0010647 271 0.047
positive regulation of cell development GO:0010720 176 0.047
chromatin modification GO:0016568 33 0.046
organic substance catabolic process GO:1901575 316 0.046
neurological system process GO:0050877 219 0.046
response to decreased oxygen levels GO:0036293 237 0.046
cellular response to endogenous stimulus GO:0071495 377 0.046
response to estrogen GO:0043627 232 0.045
cell cycle GO:0007049 101 0.045
head development GO:0060322 247 0.045
positive regulation of phosphate metabolic process GO:0045937 262 0.045
positive regulation of cellular amine metabolic process GO:0033240 3 0.045
protein complex biogenesis GO:0070271 263 0.044
cellular amine metabolic process GO:0044106 38 0.044
dna packaging GO:0006323 4 0.044
cell projection morphogenesis GO:0048858 123 0.044
positive regulation of developmental process GO:0051094 283 0.043
regulation of cell cycle GO:0051726 73 0.043
response to acid chemical GO:0001101 222 0.042
positive regulation of response to stimulus GO:0048584 285 0.041
cellular response to lipid GO:0071396 201 0.041
negative regulation of cell death GO:0060548 229 0.041
protein complex assembly GO:0006461 263 0.041
catabolic process GO:0009056 351 0.041
regulation of cell proliferation GO:0042127 359 0.041
positive regulation of cellular protein metabolic process GO:0032270 167 0.041
positive regulation of cell death GO:0010942 184 0.040
positive regulation of neurogenesis GO:0050769 165 0.040
reproductive process GO:0022414 372 0.040
alpha amino acid metabolic process GO:1901605 71 0.040
cognition GO:0050890 92 0.040
single organism organelle organization GO:1902589 180 0.039
Mouse
cell projection organization GO:0030030 302 0.039
cellular ketone metabolic process GO:0042180 51 0.038
glial cell differentiation GO:0010001 65 0.038
gland development GO:0048732 155 0.038
cell cycle checkpoint GO:0000075 2 0.037
tissue development GO:0009888 252 0.037
cellular component movement GO:0006928 248 0.037
regulation of neurogenesis GO:0050767 247 0.037
brain development GO:0007420 247 0.036
single organism catabolic process GO:0044712 283 0.036
response to corticosteroid GO:0031960 235 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.036
response to nutrient GO:0007584 248 0.035
response to ketone GO:1901654 182 0.035
behavior GO:0007610 205 0.034
neuron development GO:0048666 286 0.034
regulation of neuron differentiation GO:0045664 208 0.034
single organism behavior GO:0044708 130 0.034
positive regulation of transport GO:0051050 245 0.033
regulation of organelle organization GO:0033043 80 0.033
response to oxygen levels GO:0070482 265 0.033
organophosphate metabolic process GO:0019637 370 0.032
cell growth GO:0016049 104 0.031
aging GO:0007568 241 0.031
cell cycle process GO:0022402 57 0.031
cell part morphogenesis GO:0032990 123 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
negative regulation of apoptotic process GO:0043066 181 0.030
nucleotide metabolic process GO:0009117 279 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
positive regulation of protein modification process GO:0031401 142 0.030
response to inorganic substance GO:0010035 377 0.030
Mouse
nucleosome organization GO:0034728 1 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
response to glucocorticoid GO:0051384 223 0.030
homeostatic process GO:0042592 331 0.030
Mouse
response to reactive oxygen species GO:0000302 120 0.030
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.029
regulation of phosphorylation GO:0042325 248 0.029
gliogenesis GO:0042063 93 0.029
locomotion GO:0040011 237 0.029
growth GO:0040007 165 0.029
Mouse
negative regulation of cell differentiation GO:0045596 99 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.028
response to toxic substance GO:0009636 133 0.028
response to metal ion GO:0010038 253 0.027
regulation of signal transduction GO:0009966 318 0.027
response to estradiol GO:0032355 164 0.027
response to ethanol GO:0045471 162 0.027
response to peptide hormone GO:0043434 278 0.026
Human
negative regulation of programmed cell death GO:0043069 183 0.026
regeneration GO:0031099 163 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
carbohydrate metabolic process GO:0005975 130 0.026
single organism intracellular transport GO:1902582 166 0.025
axon development GO:0061564 96 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
cellular response to ketone GO:1901655 51 0.025
response to amino acid GO:0043200 75 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
positive regulation of signal transduction GO:0009967 175 0.024
cellular response to external stimulus GO:0071496 118 0.024
developmental growth GO:0048589 100 0.024
cell migration GO:0016477 197 0.024
regulation of cell projection organization GO:0031344 175 0.024
response to cytokine GO:0034097 215 0.024
reproductive structure development GO:0048608 128 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
multi multicellular organism process GO:0044706 138 0.023
intracellular transport GO:0046907 185 0.023
cation transport GO:0006812 382 0.023
regulation of secretion GO:0051046 224 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
blood vessel development GO:0001568 69 0.022
chromosome segregation GO:0007059 2 0.022
response to heat GO:0009408 60 0.022
regulation of neuron death GO:1901214 115 0.022
regulation of cell cycle g1 s phase transition GO:1902806 7 0.022
response to radiation GO:0009314 137 0.022
regulation of cell migration GO:0030334 128 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
cell motility GO:0048870 202 0.022
regulation of cell growth GO:0001558 85 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
reproduction GO:0000003 245 0.021
regulation of growth GO:0040008 105 0.021
Mouse
cellular homeostasis GO:0019725 252 0.021
cell type specific apoptotic process GO:0097285 134 0.021
response to vitamin GO:0033273 131 0.021
negative regulation of signaling GO:0023057 157 0.021
protein processing GO:0016485 68 0.021
organ morphogenesis GO:0009887 75 0.021
defense response GO:0006952 194 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
regulation of cellular component movement GO:0051270 150 0.021
regulation of cell motility GO:2000145 131 0.021
multicellular organismal reproductive process GO:0048609 233 0.020
regulation of anatomical structure size GO:0090066 135 0.020
regulation of immune system process GO:0002682 123 0.020
positive regulation of signaling GO:0023056 270 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
cellular component morphogenesis GO:0032989 155 0.020
cellular lipid metabolic process GO:0044255 208 0.020
regulation of neuron projection development GO:0010975 161 0.020
response to biotic stimulus GO:0009607 226 0.020
immune system process GO:0002376 204 0.020
purine containing compound metabolic process GO:0072521 253 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
multicellular organism reproduction GO:0032504 233 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.019
cellular chemical homeostasis GO:0055082 247 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
learning or memory GO:0007611 90 0.019
response to growth factor GO:0070848 189 0.019
female gonad development GO:0008585 53 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
nucleocytoplasmic transport GO:0006913 48 0.019
response to ionizing radiation GO:0010212 59 0.019
proteolysis GO:0006508 175 0.019
response to bacterium GO:0009617 200 0.019
cytoskeleton organization GO:0007010 111 0.019
regulation of catalytic activity GO:0050790 304 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
response to lipopolysaccharide GO:0032496 191 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
regulation of locomotion GO:0040012 148 0.019
cellular response to steroid hormone stimulus GO:0071383 93 0.018
epithelium development GO:0060429 96 0.018
urogenital system development GO:0001655 78 0.018
cellular response to corticosteroid stimulus GO:0071384 69 0.018
memory GO:0007613 54 0.018
multi organism reproductive process GO:0044703 262 0.018
dna integrity checkpoint GO:0031570 2 0.018
cellular catabolic process GO:0044248 295 0.018
lipid metabolic process GO:0006629 283 0.018
regulation of system process GO:0044057 208 0.018
response to wounding GO:0009611 254 0.018
female pregnancy GO:0007565 122 0.018
positive regulation of cell motility GO:2000147 97 0.018
maintenance of location GO:0051235 17 0.018
forebrain development GO:0030900 98 0.018
cell cycle phase transition GO:0044770 21 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
response to mechanical stimulus GO:0009612 134 0.018
cellular response to alcohol GO:0097306 87 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.017
double strand break repair GO:0006302 1 0.017
Human Mouse
ribonucleoside monophosphate metabolic process GO:0009161 88 0.017
cytoplasmic transport GO:0016482 115 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
negative regulation of cell cycle phase transition GO:1901988 4 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
cardiovascular system development GO:0072358 134 0.017
response to dexamethasone GO:0071548 49 0.017
regulation of protein localization GO:0032880 81 0.017
oxidation reduction process GO:0055114 304 0.017
positive regulation of immune system process GO:0002684 90 0.017
cellular macromolecule localization GO:0070727 122 0.017
female sex differentiation GO:0046660 59 0.017
response to temperature stimulus GO:0009266 94 0.017
vasculature development GO:0001944 70 0.017
regulation of protein transport GO:0051223 68 0.017
negative regulation of developmental process GO:0051093 125 0.017
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of secretion GO:0051047 140 0.016
cellular response to drug GO:0035690 30 0.016
cell morphogenesis GO:0000902 142 0.016
establishment of protein localization GO:0045184 141 0.016
response to oxidative stress GO:0006979 186 0.016
Mouse
mitotic spindle organization GO:0007052 2 0.016
embryonic pattern specification GO:0009880 1 0.016
negative regulation of cell development GO:0010721 82 0.016
ion homeostasis GO:0050801 212 0.016
regulation of dna metabolic process GO:0051052 60 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
chemical homeostasis GO:0048878 292 0.016
cellular modified amino acid metabolic process GO:0006575 61 0.016
protein oligomerization GO:0051259 191 0.016
ras protein signal transduction GO:0007265 29 0.016
cofactor metabolic process GO:0051186 95 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
muscle system process GO:0003012 115 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
gastrulation GO:0007369 2 0.015
eye morphogenesis GO:0048592 4 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
mitotic cell cycle phase transition GO:0044772 20 0.015
fatty acid metabolic process GO:0006631 99 0.015
response to carbohydrate GO:0009743 183 0.015
secretion GO:0046903 307 0.015
macromolecule localization GO:0033036 252 0.015
secretion by cell GO:0032940 248 0.015
mapk cascade GO:0000165 140 0.015
neuron death GO:0070997 127 0.015
sex differentiation GO:0007548 113 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
neuron projection morphogenesis GO:0048812 122 0.014
aromatic compound catabolic process GO:0019439 168 0.014
localization of cell GO:0051674 202 0.014
regulation of response to stress GO:0080134 126 0.014
negative regulation of molecular function GO:0044092 133 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
regulation of ion transport GO:0043269 245 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
response to hexose GO:0009746 144 0.014
nuclear transport GO:0051169 49 0.014
divalent metal ion transport GO:0070838 132 0.014
regulation of immune response GO:0050776 55 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
circadian rhythm GO:0007623 88 0.013
metal ion transport GO:0030001 289 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
reproductive system development GO:0061458 128 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
positive regulation of locomotion GO:0040017 102 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to other organism GO:0051707 220 0.013
positive regulation of intracellular protein transport GO:0090316 20 0.013
embryonic appendage morphogenesis GO:0035113 4 0.013
negative regulation of cell communication GO:0010648 158 0.013
response to monosaccharide GO:0034284 159 0.013
response to hydrogen peroxide GO:0042542 89 0.013
macromolecule catabolic process GO:0009057 58 0.013
chromatin remodeling GO:0006338 3 0.013
nucleoside metabolic process GO:0009116 179 0.013
development of primary sexual characteristics GO:0045137 107 0.013
tube development GO:0035295 89 0.013
cell cell signaling GO:0007267 335 0.013
heterocycle catabolic process GO:0046700 167 0.013
response to antibiotic GO:0046677 39 0.013
cell cycle g1 s phase transition GO:0044843 13 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
spindle organization GO:0007051 2 0.013
covalent chromatin modification GO:0016569 30 0.013
developmental process involved in reproduction GO:0003006 159 0.013
negative regulation of signal transduction GO:0009968 83 0.013
axis specification GO:0009798 4 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
regulation of intracellular transport GO:0032386 65 0.013
regulation of secretion by cell GO:1903530 208 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
negative regulation of transport GO:0051051 136 0.013
cellular ion homeostasis GO:0006873 184 0.013
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.013
multicellular organism growth GO:0035264 1 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
dna replication GO:0006260 37 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
regulation of cell cycle process GO:0010564 31 0.012
response to purine containing compound GO:0014074 126 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
cellular protein localization GO:0034613 122 0.012
actin filament based process GO:0030029 86 0.012
motor neuron axon guidance GO:0008045 1 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
cellular response to metal ion GO:0071248 55 0.012
mitotic cell cycle GO:0000278 49 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
nitrogen compound transport GO:0071705 229 0.012
regulation of membrane potential GO:0042391 110 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
glucan metabolic process GO:0044042 23 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
translation GO:0006412 35 0.012
ovulation cycle GO:0042698 67 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.012
circulatory system process GO:0003013 183 0.012
response to fatty acid GO:0070542 65 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.011
g1 s transition of mitotic cell cycle GO:0000082 12 0.011
regulation of catabolic process GO:0009894 113 0.011
response to alkaloid GO:0043279 132 0.011
chemosensory behavior GO:0007635 2 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
heart morphogenesis GO:0003007 3 0.011
protein transport GO:0015031 132 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of cell adhesion GO:0030155 52 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
single organism nuclear import GO:1902593 35 0.011
apoptotic signaling pathway GO:0097190 27 0.011
response to light stimulus GO:0009416 52 0.011
mitotic cell cycle process GO:1903047 35 0.011
spermatogenesis GO:0007283 99 0.011
camera type eye development GO:0043010 48 0.011
calcium ion homeostasis GO:0055074 162 0.011
tetrahydrofolate metabolic process GO:0046653 9 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
regulation of mapk cascade GO:0043408 116 0.011
innate immune response GO:0045087 35 0.011
limb morphogenesis GO:0035108 4 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
organophosphate catabolic process GO:0046434 148 0.011
regulation of cell cycle phase transition GO:1901987 12 0.011
gonad development GO:0008406 104 0.011
chromatin disassembly GO:0031498 1 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
negative regulation of cellular component organization GO:0051129 83 0.010
gamete generation GO:0007276 124 0.010
liver development GO:0001889 90 0.010
cell activation GO:0001775 97 0.010
rna localization GO:0006403 4 0.010
cellular response to glucocorticoid stimulus GO:0071385 68 0.010
muscle structure development GO:0061061 87 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
protein autophosphorylation GO:0046777 66 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
signal release GO:0023061 145 0.010
metal ion homeostasis GO:0055065 186 0.010
protein heterooligomerization GO:0051291 89 0.010
negative regulation of neuron differentiation GO:0045665 62 0.010
organic anion transport GO:0015711 132 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010
regulation of hormone levels GO:0010817 187 0.010

Parp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.010