Rattus norvegicus

29 known processes

Pc

pyruvate carboxylase

(Aliases: Pcx)

Pc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.205
organic acid metabolic process GO:0006082 292 0.186
monocarboxylic acid metabolic process GO:0032787 152 0.156
carboxylic acid biosynthetic process GO:0046394 83 0.151
single organism biosynthetic process GO:0044711 342 0.130
organic acid biosynthetic process GO:0016053 83 0.120
lipid biosynthetic process GO:0008610 128 0.098
organophosphate metabolic process GO:0019637 370 0.090
single organism catabolic process GO:0044712 283 0.085
homeostatic process GO:0042592 331 0.083
organic substance catabolic process GO:1901575 316 0.082
cellular amino acid metabolic process GO:0006520 107 0.081
chemical homeostasis GO:0048878 292 0.077
carboxylic acid metabolic process GO:0019752 289 0.077
carbohydrate derivative metabolic process GO:1901135 346 0.076
small molecule biosynthetic process GO:0044283 124 0.063
catabolic process GO:0009056 351 0.062
lipid metabolic process GO:0006629 283 0.056
response to nutrient levels GO:0031667 370 0.054
fatty acid metabolic process GO:0006631 99 0.052
protein phosphorylation GO:0006468 345 0.051
response to extracellular stimulus GO:0009991 380 0.050
positive regulation of biosynthetic process GO:0009891 319 0.050
regulation of rna biosynthetic process GO:2001141 381 0.050
sulfur compound biosynthetic process GO:0044272 19 0.048
cellular lipid metabolic process GO:0044255 208 0.044
nucleoside phosphate metabolic process GO:0006753 283 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
regulation of multicellular organismal development GO:2000026 376 0.043
cellular response to stress GO:0033554 269 0.043
regulation of cellular component organization GO:0051128 368 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
cation transport GO:0006812 382 0.041
inorganic ion transmembrane transport GO:0098660 229 0.041
nitrogen compound transport GO:0071705 229 0.041
anatomical structure morphogenesis GO:0009653 298 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
response to glucocorticoid GO:0051384 223 0.040
positive regulation of phosphate metabolic process GO:0045937 262 0.039
glycosyl compound metabolic process GO:1901657 182 0.039
amine metabolic process GO:0009308 38 0.039
secretion GO:0046903 307 0.039
programmed cell death GO:0012501 392 0.038
response to metal ion GO:0010038 253 0.038
macromolecular complex assembly GO:0065003 273 0.038
hormone secretion GO:0046879 115 0.038
regulation of phosphorylation GO:0042325 248 0.038
cellular ketone metabolic process GO:0042180 51 0.038
ion transmembrane transport GO:0034220 365 0.038
organic acid transport GO:0015849 116 0.038
transmembrane transport GO:0055085 412 0.038
regulation of hormone levels GO:0010817 187 0.037
intracellular signal transduction GO:0035556 314 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
heterocycle catabolic process GO:0046700 167 0.036
cellular amino acid biosynthetic process GO:0008652 32 0.036
positive regulation of developmental process GO:0051094 283 0.036
tissue development GO:0009888 252 0.035
purine ribonucleoside metabolic process GO:0046128 168 0.035
cellular amine metabolic process GO:0044106 38 0.035
cellular component assembly GO:0022607 360 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
response to peptide GO:1901652 292 0.035
cellular component biogenesis GO:0044085 368 0.034
central nervous system development GO:0007417 311 0.034
organonitrogen compound biosynthetic process GO:1901566 167 0.034
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
regulation of secretion by cell GO:1903530 208 0.034
purine ribonucleoside catabolic process GO:0046130 124 0.034
regulation of neurogenesis GO:0050767 247 0.034
negative regulation of metabolic process GO:0009892 331 0.034
ribonucleoside metabolic process GO:0009119 174 0.034
nucleotide metabolic process GO:0009117 279 0.033
regulation of molecular function GO:0065009 398 0.033
response to organophosphorus GO:0046683 102 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.033
positive regulation of transcription dna templated GO:0045893 197 0.032
ion homeostasis GO:0050801 212 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
regulation of neuron projection development GO:0010975 161 0.032
secretion by cell GO:0032940 248 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.031
macromolecule localization GO:0033036 252 0.031
purine nucleoside metabolic process GO:0042278 169 0.031
regulation of ion transport GO:0043269 245 0.031
response to inorganic substance GO:0010035 377 0.031
response to insulin GO:0032868 133 0.030
organic anion transport GO:0015711 132 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
head development GO:0060322 247 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
cellular response to hormone stimulus GO:0032870 247 0.030
nucleotide catabolic process GO:0009166 139 0.030
single organism reproductive process GO:0044702 297 0.030
positive regulation of cell differentiation GO:0045597 217 0.029
transcription dna templated GO:0006351 377 0.029
response to nutrient GO:0007584 248 0.029
rna biosynthetic process GO:0032774 380 0.029
response to peptide hormone GO:0043434 278 0.029
ribonucleoside triphosphate catabolic process GO:0009203 122 0.029
response to corticosteroid GO:0031960 235 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
response to decreased oxygen levels GO:0036293 237 0.029
cell cell signaling GO:0007267 335 0.029
rna metabolic process GO:0016070 406 0.028
cofactor metabolic process GO:0051186 95 0.028
cation homeostasis GO:0055080 195 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
cellular homeostasis GO:0019725 252 0.027
brain development GO:0007420 247 0.027
nucleoside metabolic process GO:0009116 179 0.027
response to camp GO:0051591 91 0.027
carbohydrate catabolic process GO:0016052 40 0.027
cellular chemical homeostasis GO:0055082 247 0.027
carbohydrate metabolic process GO:0005975 130 0.026
cellular modified amino acid metabolic process GO:0006575 61 0.026
ribonucleotide catabolic process GO:0009261 136 0.026
positive regulation of cell development GO:0010720 176 0.026
response to oxygen levels GO:0070482 265 0.026
regulation of cell development GO:0060284 263 0.026
regulation of cell differentiation GO:0045595 320 0.026
protein complex biogenesis GO:0070271 263 0.026
neuron differentiation GO:0030182 368 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
sulfur compound metabolic process GO:0006790 70 0.025
regulation of cellular localization GO:0060341 263 0.025
positive regulation of nervous system development GO:0051962 178 0.025
positive regulation of protein modification process GO:0031401 142 0.025
response to purine containing compound GO:0014074 126 0.025
multi organism reproductive process GO:0044703 262 0.025
regulation of transcription dna templated GO:0006355 374 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
circulatory system development GO:0072359 134 0.025
metal ion homeostasis GO:0055065 186 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
protein complex subunit organization GO:0071822 302 0.024
apoptotic process GO:0006915 381 0.024
hexose metabolic process GO:0019318 58 0.024
regulation of neuron differentiation GO:0045664 208 0.024
nucleic acid templated transcription GO:0097659 379 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
monocarboxylic acid biosynthetic process GO:0072330 48 0.024
cellular ion homeostasis GO:0006873 184 0.024
nucleoside catabolic process GO:0009164 126 0.024
reproductive process GO:0022414 372 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
regulation of secretion GO:0051046 224 0.023
cellular response to lipid GO:0071396 201 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
purine nucleoside triphosphate catabolic process GO:0009146 122 0.023
positive regulation of molecular function GO:0044093 230 0.023
regulation of cell proliferation GO:0042127 359 0.023
purine containing compound metabolic process GO:0072521 253 0.023
protein complex assembly GO:0006461 263 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
regulation of catalytic activity GO:0050790 304 0.022
glycosyl compound catabolic process GO:1901658 126 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
purine containing compound catabolic process GO:0072523 138 0.022
response to acid chemical GO:0001101 222 0.022
multicellular organism reproduction GO:0032504 233 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
regulation of rna metabolic process GO:0051252 391 0.022
positive regulation of cell communication GO:0010647 271 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
cellular response to insulin stimulus GO:0032869 81 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
aromatic compound catabolic process GO:0019439 168 0.022
cellular catabolic process GO:0044248 295 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
reproduction GO:0000003 245 0.021
purine ribonucleotide catabolic process GO:0009154 136 0.021
anion transport GO:0006820 178 0.021
regulation of nervous system development GO:0051960 264 0.021
negative regulation of gene expression GO:0010629 199 0.021
neuron development GO:0048666 286 0.021
protein oligomerization GO:0051259 191 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
purine nucleoside catabolic process GO:0006152 124 0.021
regulation of signal transduction GO:0009966 318 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
signal release GO:0023061 145 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
cellular carbohydrate metabolic process GO:0044262 72 0.020
organelle organization GO:0006996 266 0.020
sensory organ development GO:0007423 74 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
growth GO:0040007 165 0.020
ras protein signal transduction GO:0007265 29 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
cellular cation homeostasis GO:0030003 180 0.019
response to hypoxia GO:0001666 231 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
response to temperature stimulus GO:0009266 94 0.019
regulation of lipid metabolic process GO:0019216 68 0.019
cellular amino acid catabolic process GO:0009063 21 0.019
regulation of protein metabolic process GO:0051246 289 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
organophosphate catabolic process GO:0046434 148 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
acetyl coa metabolic process GO:0006084 17 0.019
coenzyme metabolic process GO:0006732 86 0.019
positive regulation of transport GO:0051050 245 0.019
positive regulation of gene expression GO:0010628 244 0.019
positive regulation of signaling GO:0023056 270 0.019
hormone transport GO:0009914 121 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
neuron projection morphogenesis GO:0048812 122 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
regulation of homeostatic process GO:0032844 101 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
monosaccharide metabolic process GO:0005996 61 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
single organism carbohydrate catabolic process GO:0044724 40 0.018
multicellular organism growth GO:0035264 1 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
carboxylic acid catabolic process GO:0046395 49 0.018
metal ion transport GO:0030001 289 0.018
cellular response to reactive oxygen species GO:0034614 55 0.018
cation transmembrane transport GO:0098655 263 0.018
regulation of hydrolase activity GO:0051336 143 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
negative regulation of signaling GO:0023057 157 0.017
cellular response to peptide GO:1901653 133 0.017
regulation of protein modification process GO:0031399 194 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
locomotion GO:0040011 237 0.017
cell projection organization GO:0030030 302 0.017
sexual reproduction GO:0019953 148 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
neurological system process GO:0050877 219 0.017
cellular modified amino acid biosynthetic process GO:0042398 18 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
regulation of growth GO:0040008 105 0.017
positive regulation of rna metabolic process GO:0051254 203 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
gamete generation GO:0007276 124 0.016
acyl coa metabolic process GO:0006637 28 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
single organism intracellular transport GO:1902582 166 0.016
carboxylic acid transport GO:0046942 115 0.016
peptidyl amino acid modification GO:0018193 126 0.016
intracellular transport GO:0046907 185 0.016
response to estrogen GO:0043627 232 0.016
response to estradiol GO:0032355 164 0.016
amide transport GO:0042886 105 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.015
cellular response to external stimulus GO:0071496 118 0.015
gland development GO:0048732 155 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
response to oxidative stress GO:0006979 186 0.015
regulation of response to external stimulus GO:0032101 106 0.015
protein transport GO:0015031 132 0.015
regulation of cell projection organization GO:0031344 175 0.015
cellular component morphogenesis GO:0032989 155 0.015
response to wounding GO:0009611 254 0.015
cellular component movement GO:0006928 248 0.015
circulatory system process GO:0003013 183 0.014
axon development GO:0061564 96 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
synaptic transmission GO:0007268 235 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
behavioral response to ethanol GO:0048149 1 0.014
developmental process involved in reproduction GO:0003006 159 0.014
insulin secretion GO:0030073 69 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
establishment of protein localization GO:0045184 141 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
cell motility GO:0048870 202 0.014
response to lipopolysaccharide GO:0032496 191 0.014
response to ketone GO:1901654 182 0.014
response to growth factor GO:0070848 189 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
regulation of transferase activity GO:0051338 123 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of synaptic transmission GO:0050804 141 0.014
chromosome segregation GO:0007059 2 0.014
peptide transport GO:0015833 97 0.013
protein homooligomerization GO:0051260 91 0.013
negative regulation of cell communication GO:0010648 158 0.013
regulation of catabolic process GO:0009894 113 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
cytokine mediated signaling pathway GO:0019221 43 0.013
peptide hormone secretion GO:0030072 84 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cell part morphogenesis GO:0032990 123 0.013
glucose metabolic process GO:0006006 52 0.013
regulation of system process GO:0044057 208 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
negative regulation of molecular function GO:0044092 133 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
alpha amino acid biosynthetic process GO:1901607 23 0.013
neuron projection development GO:0031175 273 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
transmission of nerve impulse GO:0019226 42 0.013
monocarboxylic acid transport GO:0015718 52 0.013
regulation of apoptotic process GO:0042981 335 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
peptide secretion GO:0002790 86 0.012
behavior GO:0007610 205 0.012
protein localization GO:0008104 191 0.012
positive regulation of homeostatic process GO:0032846 49 0.012
blood circulation GO:0008015 183 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
dicarboxylic acid catabolic process GO:0043649 1 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
multicellular organismal homeostasis GO:0048871 49 0.012
macroautophagy GO:0016236 4 0.012
response to mechanical stimulus GO:0009612 134 0.012
cell migration GO:0016477 197 0.012
response to cadmium ion GO:0046686 35 0.012
anion transmembrane transport GO:0098656 77 0.012
single organism behavior GO:0044708 130 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
response to cytokine GO:0034097 215 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
regulation of response to stress GO:0080134 126 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
alcohol metabolic process GO:0006066 77 0.012
thioester biosynthetic process GO:0035384 7 0.012
response to monosaccharide GO:0034284 159 0.012
regulation of cellular response to stress GO:0080135 49 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of purine nucleotide catabolic process GO:0033121 65 0.012
gtp catabolic process GO:0006184 71 0.012
regulation of programmed cell death GO:0043067 341 0.012
regulation of protein kinase activity GO:0045859 105 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
organic hydroxy compound transport GO:0015850 77 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
positive regulation of signal transduction GO:0009967 175 0.011
male gamete generation GO:0048232 99 0.011
single organism organelle organization GO:1902589 180 0.011
regulation of cellular component movement GO:0051270 150 0.011
positive regulation of cell death GO:0010942 184 0.011
spermatogenesis GO:0007283 99 0.011
dephosphorylation GO:0016311 98 0.011
localization of cell GO:0051674 202 0.011
alcohol biosynthetic process GO:0046165 38 0.011
axis specification GO:0009798 4 0.011
anterior posterior pattern specification GO:0009952 1 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of locomotion GO:0040012 148 0.011
immune response GO:0006955 104 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
phospholipid biosynthetic process GO:0008654 29 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
divalent metal ion transport GO:0070838 132 0.011
protein processing GO:0016485 68 0.011
salivary gland development GO:0007431 3 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
heart morphogenesis GO:0003007 3 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
glycerolipid metabolic process GO:0046486 67 0.011
regulation of hormone secretion GO:0046883 106 0.011
hormone metabolic process GO:0042445 69 0.010
positive regulation of kinase activity GO:0033674 77 0.010
axonogenesis GO:0007409 71 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
adult locomotory behavior GO:0008344 4 0.010
embryonic pattern specification GO:0009880 1 0.010
response to ethanol GO:0045471 162 0.010
regulation of anatomical structure size GO:0090066 135 0.010
regulation of kinase activity GO:0043549 117 0.010
fatty acid biosynthetic process GO:0006633 33 0.010
aging GO:0007568 241 0.010
multicellular organismal signaling GO:0035637 44 0.010

Pc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.084
Human
disease of metabolism DOID:0014667 0 0.084
Human
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
central nervous system disease DOID:331 0 0.014
brain disease DOID:936 0 0.012
amino acid metabolic disorder DOID:9252 0 0.012
organic acidemia DOID:0060159 0 0.010