Rattus norvegicus

124 known processes

Pcsk1

proprotein convertase subtilisin/kexin type 1

(Aliases: PC3,PC1,BDP)

Pcsk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
secretion GO:0046903 307 0.662
inflammatory response GO:0006954 150 0.320
regulation of cellular localization GO:0060341 263 0.304
positive regulation of transport GO:0051050 245 0.290
cellular response to organic cyclic compound GO:0071407 202 0.267
regulation of secretion GO:0051046 224 0.243
cellular calcium ion homeostasis GO:0006874 160 0.238
response to nutrient levels GO:0031667 370 0.237
response to inorganic substance GO:0010035 377 0.228
positive regulation of multicellular organismal process GO:0051240 387 0.216
cell cell signaling GO:0007267 335 0.212
response to metal ion GO:0010038 253 0.208
response to decreased oxygen levels GO:0036293 237 0.198
positive regulation of biosynthetic process GO:0009891 319 0.176
central nervous system development GO:0007417 311 0.151
macromolecule localization GO:0033036 252 0.148
g protein coupled receptor signaling pathway GO:0007186 242 0.145
programmed cell death GO:0012501 392 0.145
negative regulation of multicellular organismal process GO:0051241 203 0.143
regulation of synaptic transmission GO:0050804 141 0.143
divalent metal ion transport GO:0070838 132 0.141
circulatory system process GO:0003013 183 0.138
regulation of programmed cell death GO:0043067 341 0.137
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.129
response to hypoxia GO:0001666 231 0.127
apoptotic process GO:0006915 381 0.127
tissue development GO:0009888 252 0.124
cellular response to endogenous stimulus GO:0071495 377 0.124
Rat
positive regulation of secretion by cell GO:1903532 128 0.123
positive regulation of secretion GO:0051047 140 0.122
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.120
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.120
calcium ion homeostasis GO:0055074 162 0.116
peptide hormone secretion GO:0030072 84 0.116
synaptic transmission GO:0007268 235 0.115
response to oxygen levels GO:0070482 265 0.112
protein transport GO:0015031 132 0.111
response to extracellular stimulus GO:0009991 380 0.111
regulation of nucleic acid templated transcription GO:1903506 380 0.109
cellular response to nitrogen compound GO:1901699 210 0.107
multi multicellular organism process GO:0044706 138 0.107
female pregnancy GO:0007565 122 0.104
response to corticosteroid GO:0031960 235 0.104
metal ion homeostasis GO:0055065 186 0.103
nitrogen compound transport GO:0071705 229 0.102
localization of cell GO:0051674 202 0.100
Rat
blood circulation GO:0008015 183 0.099
regulation of apoptotic process GO:0042981 335 0.096
positive regulation of cellular biosynthetic process GO:0031328 295 0.092
cellular response to oxygen containing compound GO:1901701 386 0.092
response to peptide hormone GO:0043434 278 0.091
regulation of hormone levels GO:0010817 187 0.091
positive regulation of developmental process GO:0051094 283 0.090
neuron neuron synaptic transmission GO:0007270 60 0.087
regulation of secretion by cell GO:1903530 208 0.086
oxoacid metabolic process GO:0043436 290 0.085
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.083
regulation of rna metabolic process GO:0051252 391 0.083
regulation of cellular component organization GO:0051128 368 0.082
response to glucocorticoid GO:0051384 223 0.082
establishment of protein localization GO:0045184 141 0.080
regulation of hormone secretion GO:0046883 106 0.080
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.080
peptide secretion GO:0002790 86 0.079
cellular component movement GO:0006928 248 0.079
Rat
brain development GO:0007420 247 0.077
cell migration GO:0016477 197 0.077
Rat
synaptic transmission glutamatergic GO:0035249 33 0.077
cellular lipid metabolic process GO:0044255 208 0.076
secretion by cell GO:0032940 248 0.075
single organism reproductive process GO:0044702 297 0.075
locomotion GO:0040011 237 0.075
Rat
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.075
cell projection organization GO:0030030 302 0.075
negative regulation of response to tumor cell GO:0002835 2 0.075
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.074
intracellular signal transduction GO:0035556 314 0.073
reproduction GO:0000003 245 0.073
protein phosphorylation GO:0006468 345 0.073
cellular response to peptide GO:1901653 133 0.072
response to peptide GO:1901652 292 0.072
hormone secretion GO:0046879 115 0.072
vesicle mediated transport GO:0016192 181 0.071
regulation of rna biosynthetic process GO:2001141 381 0.071
organophosphate metabolic process GO:0019637 370 0.071
negative regulation of immune response to tumor cell GO:0002838 2 0.070
regulation of system process GO:0044057 208 0.069
multi organism reproductive process GO:0044703 262 0.067
organonitrogen compound biosynthetic process GO:1901566 167 0.064
Mouse
reproductive process GO:0022414 372 0.064
regulation of blood pressure GO:0008217 83 0.064
positive regulation of protein modification process GO:0031401 142 0.063
nucleoside phosphate biosynthetic process GO:1901293 102 0.062
insulin secretion GO:0030073 69 0.061
neuron development GO:0048666 286 0.061
regulation of establishment of protein localization GO:0070201 69 0.060
regulation of phosphorus metabolic process GO:0051174 349 0.060
cellular response to hormone stimulus GO:0032870 247 0.060
negative regulation of defense response GO:0031348 19 0.060
cellular metal ion homeostasis GO:0006875 172 0.060
negative regulation of cellular metabolic process GO:0031324 281 0.059
amide transport GO:0042886 105 0.059
regulation of transcription dna templated GO:0006355 374 0.059
carbohydrate catabolic process GO:0016052 40 0.058
intracellular transport GO:0046907 185 0.058
cation homeostasis GO:0055080 195 0.058
amine transport GO:0015837 57 0.058
negative regulation of transport GO:0051051 136 0.057
regulation of cell proliferation GO:0042127 359 0.056
positive regulation of hormone secretion GO:0046887 65 0.056
developmental growth GO:0048589 100 0.056
single organism intracellular transport GO:1902582 166 0.056
ribose phosphate biosynthetic process GO:0046390 87 0.056
hormone transport GO:0009914 121 0.056
reproductive system development GO:0061458 128 0.056
neurological system process GO:0050877 219 0.056
peptide transport GO:0015833 97 0.055
mapk cascade GO:0000165 140 0.055
negative regulation of biosynthetic process GO:0009890 168 0.055
regulation of neuron differentiation GO:0045664 208 0.054
cellular chemical homeostasis GO:0055082 247 0.054
single organism carbohydrate catabolic process GO:0044724 40 0.053
phosphatidylinositol dephosphorylation GO:0046856 4 0.053
organic hydroxy compound transport GO:0015850 77 0.053
cation transport GO:0006812 382 0.053
head development GO:0060322 247 0.053
cellular response to organonitrogen compound GO:0071417 197 0.052
positive regulation of cellular component organization GO:0051130 200 0.052
cellular response to corticosteroid stimulus GO:0071384 69 0.052
regulation of nervous system development GO:0051960 264 0.052
response to mechanical stimulus GO:0009612 134 0.051
organelle organization GO:0006996 266 0.051
response to purine containing compound GO:0014074 126 0.051
cellular response to stress GO:0033554 269 0.050
response to organophosphorus GO:0046683 102 0.050
transcription dna templated GO:0006351 377 0.049
signal transduction by phosphorylation GO:0023014 144 0.049
single organism catabolic process GO:0044712 283 0.049
chemical homeostasis GO:0048878 292 0.049
regulation of angiogenesis GO:0045765 39 0.047
exocytosis GO:0006887 60 0.046
positive regulation of long term synaptic potentiation GO:1900273 4 0.046
amine metabolic process GO:0009308 38 0.046
response to cocaine GO:0042220 39 0.046
cellular ion homeostasis GO:0006873 184 0.045
regulation of response to external stimulus GO:0032101 106 0.045
regulation of peptide transport GO:0090087 87 0.044
response to carbohydrate GO:0009743 183 0.044
multicellular organismal signaling GO:0035637 44 0.044
negative regulation of metabolic process GO:0009892 331 0.044
response to tumor cell GO:0002347 4 0.043
positive regulation of peptide hormone secretion GO:0090277 50 0.043
neurotransmitter gated ion channel clustering GO:0072578 3 0.043
cellular cation homeostasis GO:0030003 180 0.043
ossification GO:0001503 70 0.042
cellular response to tumor necrosis factor GO:0071356 46 0.042
positive regulation of programmed cell death GO:0043068 157 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
negative regulation of ion transport GO:0043271 51 0.042
purine nucleotide biosynthetic process GO:0006164 83 0.042
regulation of protein transport GO:0051223 68 0.042
cellular response to lipid GO:0071396 201 0.042
positive regulation of apoptotic process GO:0043065 154 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
positive regulation of cell death GO:0010942 184 0.041
negative regulation of developmental process GO:0051093 125 0.041
ribonucleotide biosynthetic process GO:0009260 85 0.041
response to starvation GO:0042594 59 0.041
cellular macromolecule localization GO:0070727 122 0.040
defense response GO:0006952 194 0.040
regulation of blood circulation GO:1903522 110 0.040
regulation of peptide hormone secretion GO:0090276 80 0.040
cellular response to peptide hormone stimulus GO:0071375 120 0.039
regulation of molecular function GO:0065009 398 0.039
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.039
nucleic acid templated transcription GO:0097659 379 0.039
homeostatic process GO:0042592 331 0.039
regulation of synaptic transmission glutamatergic GO:0051966 26 0.039
temperature homeostasis GO:0001659 17 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
lipid metabolic process GO:0006629 283 0.039
cellular response to alkaloid GO:0071312 25 0.039
calcium ion import GO:0070509 22 0.038
regulation of camp biosynthetic process GO:0030817 38 0.037
ion homeostasis GO:0050801 212 0.037
smooth muscle contraction GO:0006939 37 0.037
organic acid metabolic process GO:0006082 292 0.037
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.037
rna biosynthetic process GO:0032774 380 0.036
regulation of cell differentiation GO:0045595 320 0.036
cellular amine metabolic process GO:0044106 38 0.036
dephosphorylation GO:0016311 98 0.036
aging GO:0007568 241 0.036
Rat
response to nutrient GO:0007584 248 0.036
negative regulation of cell differentiation GO:0045596 99 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
hormone metabolic process GO:0042445 69 0.035
transmission of nerve impulse GO:0019226 42 0.035
camp biosynthetic process GO:0006171 47 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
positive regulation of cell development GO:0010720 176 0.035
ion transmembrane transport GO:0034220 365 0.035
regulation of ion transport GO:0043269 245 0.035
cellular homeostasis GO:0019725 252 0.035
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.035
single organism cellular localization GO:1902580 102 0.034
negative regulation of cell development GO:0010721 82 0.034
regulation of nucleotide metabolic process GO:0006140 117 0.034
development of primary sexual characteristics GO:0045137 107 0.034
regulation of peptide secretion GO:0002791 82 0.034
cellular response to glucocorticoid stimulus GO:0071385 68 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.034
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
protein secretion GO:0009306 34 0.034
regulation of neurogenesis GO:0050767 247 0.033
negative regulation of cell proliferation GO:0008285 119 0.033
camp metabolic process GO:0046058 63 0.033
small gtpase mediated signal transduction GO:0007264 36 0.033
artery smooth muscle contraction GO:0014824 4 0.033
heart development GO:0007507 72 0.033
negative regulation of gene expression GO:0010629 199 0.033
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
neuron projection development GO:0031175 273 0.033
calcium ion transport GO:0006816 131 0.032
gastrulation GO:0007369 2 0.032
regeneration GO:0031099 163 0.032
immune response GO:0006955 104 0.032
divalent inorganic cation homeostasis GO:0072507 165 0.032
gliogenesis GO:0042063 93 0.032
response to estradiol GO:0032355 164 0.032
epithelium development GO:0060429 96 0.032
positive regulation of molecular function GO:0044093 230 0.032
renin secretion into blood stream GO:0002001 1 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.032
response to biotic stimulus GO:0009607 226 0.032
positive regulation of nucleic acid templated transcription GO:1903508 197 0.032
regulation of protein metabolic process GO:0051246 289 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
response to camp GO:0051591 91 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
phospholipid metabolic process GO:0006644 61 0.031
regulation of renin secretion into blood stream GO:1900133 1 0.031
negative regulation of secretion by cell GO:1903531 72 0.031
regulation of lyase activity GO:0051339 22 0.031
regulation of protein localization GO:0032880 81 0.031
regulation of body fluid levels GO:0050878 90 0.031
vascular process in circulatory system GO:0003018 96 0.031
cellular divalent inorganic cation homeostasis GO:0072503 162 0.031
multicellular organism reproduction GO:0032504 233 0.031
negative regulation of nucleic acid templated transcription GO:1903507 117 0.031
positive regulation of saliva secretion GO:0046878 3 0.031
regulation of locomotion GO:0040012 148 0.030
Rat
positive regulation of rna metabolic process GO:0051254 203 0.030
biological adhesion GO:0022610 110 0.030
regulation of catalytic activity GO:0050790 304 0.030
negative regulation of innate immune response GO:0045824 4 0.030
regulation of adenylate cyclase activity GO:0045761 18 0.030
regulation of neuron projection development GO:0010975 161 0.029
gland development GO:0048732 155 0.029
neuron differentiation GO:0030182 368 0.029
urinary tract smooth muscle contraction GO:0014848 4 0.029
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
carbohydrate derivative biosynthetic process GO:1901137 124 0.029
positive regulation of peptide secretion GO:0002793 52 0.029
muscle system process GO:0003012 115 0.029
negative regulation of neurogenesis GO:0050768 78 0.029
regulation of vasculature development GO:1901342 44 0.029
ras protein signal transduction GO:0007265 29 0.029
cellular response to steroid hormone stimulus GO:0071383 93 0.029
cyclic nucleotide biosynthetic process GO:0009190 63 0.029
negative regulation of cell death GO:0060548 229 0.028
signal release GO:0023061 145 0.028
n methyl d aspartate receptor clustering GO:0097114 2 0.028
transmembrane transport GO:0055085 412 0.028
protein localization GO:0008104 191 0.028
rna metabolic process GO:0016070 406 0.028
single organism behavior GO:0044708 130 0.028
purine containing compound biosynthetic process GO:0072522 85 0.028
regulation of muscle system process GO:0090257 79 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
regulation of cyclase activity GO:0031279 21 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
vasculature development GO:0001944 70 0.027
reproductive structure development GO:0048608 128 0.027
regulation of response to stress GO:0080134 126 0.027
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
behavior GO:0007610 205 0.027
cellular carbohydrate metabolic process GO:0044262 72 0.027
cognition GO:0050890 92 0.026
adult locomotory behavior GO:0008344 4 0.026
catabolic process GO:0009056 351 0.026
negative regulation of molecular function GO:0044092 133 0.026
reactive oxygen species biosynthetic process GO:1903409 8 0.026
positive regulation of camp biosynthetic process GO:0030819 28 0.026
regulation of insulin secretion GO:0050796 65 0.026
divalent inorganic cation transport GO:0072511 134 0.026
tissue remodeling GO:0048771 40 0.026
sexual reproduction GO:0019953 148 0.026
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.026
cellular catabolic process GO:0044248 295 0.025
neuropeptide signaling pathway GO:0007218 29 0.025
cardiac chamber development GO:0003205 1 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
catecholamine secretion GO:0050432 33 0.025
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
organic substance catabolic process GO:1901575 316 0.025
cell motility GO:0048870 202 0.025
Rat
ribose phosphate metabolic process GO:0019693 235 0.025
cardiovascular system development GO:0072358 134 0.025
positive regulation of cell communication GO:0010647 271 0.025
Rat
growth GO:0040007 165 0.025
response to wounding GO:0009611 254 0.025
regulation of blood vessel size GO:0050880 89 0.024
regulation of cell development GO:0060284 263 0.024
acute inflammatory response GO:0002526 58 0.024
learning or memory GO:0007611 90 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
organ regeneration GO:0031100 101 0.024
positive regulation of nucleotide metabolic process GO:0045981 91 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
immune system process GO:0002376 204 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of phosphorylation GO:0042325 248 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
response to tumor necrosis factor GO:0034612 56 0.024
tube development GO:0035295 89 0.024
regulation of cell migration GO:0030334 128 0.024
Rat
developmental growth involved in morphogenesis GO:0060560 33 0.023
purine ribonucleotide biosynthetic process GO:0009152 81 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
regulation of synaptic plasticity GO:0048167 70 0.023
sequestering of metal ion GO:0051238 9 0.023
negative regulation of smooth muscle contraction GO:0045986 7 0.023
regulation of smooth muscle contraction GO:0006940 29 0.023
feeding behavior GO:0007631 53 0.023
olfactory learning GO:0008355 1 0.023
cell growth GO:0016049 104 0.023
response to external biotic stimulus GO:0043207 221 0.023
regulation of catecholamine secretion GO:0050433 32 0.023
circulatory system development GO:0072359 134 0.023
synaptic transmission gabaergic GO:0051932 22 0.023
positive regulation of signaling GO:0023056 270 0.023
Rat
organelle localization GO:0051640 55 0.023
axon development GO:0061564 96 0.022
regulation of exocytosis GO:0017157 37 0.022
renal system process GO:0003014 40 0.022
positive regulation of renin secretion into blood stream GO:1900135 1 0.022
positive regulation of immune system process GO:0002684 90 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
response to calcium ion GO:0051592 59 0.022
response to cold GO:0009409 29 0.022
response to vitamin d GO:0033280 34 0.022
response to estrogen GO:0043627 232 0.022
regulation of mapk cascade GO:0043408 116 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
regulation of tube size GO:0035150 89 0.022
salivary gland development GO:0007431 3 0.022
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.022
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.022
cell adhesion GO:0007155 110 0.022
respiratory system process GO:0003016 3 0.021
regulation of cell projection organization GO:0031344 175 0.021
response to cytokine GO:0034097 215 0.021
regulation of calcium ion transport GO:0051924 77 0.021
response to glucose GO:0009749 136 0.021
muscle contraction GO:0006936 88 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
neuronal action potential GO:0019228 35 0.021
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.021
sensory perception GO:0007600 101 0.021
regulation of cellular component movement GO:0051270 150 0.021
Rat
positive regulation of cell differentiation GO:0045597 217 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
positive regulation of blood circulation GO:1903524 65 0.021
sequestering of calcium ion GO:0051208 8 0.021
monoamine transport GO:0015844 43 0.021
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
tonic smooth muscle contraction GO:0014820 4 0.021
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.020
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.020
response to ethanol GO:0045471 162 0.020
reactive nitrogen species metabolic process GO:2001057 1 0.020
negative regulation of cellular component organization GO:0051129 83 0.020
regulation of muscle contraction GO:0006937 53 0.020
positive regulation of adenylate cyclase activity GO:0045762 12 0.020
positive regulation of camp metabolic process GO:0030816 31 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
negative regulation of secretion GO:0051048 82 0.020
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.020
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.020
sex differentiation GO:0007548 113 0.020
carbohydrate metabolic process GO:0005975 130 0.020
regulation of purine nucleotide catabolic process GO:0033121 65 0.020
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.020
lipid modification GO:0030258 52 0.019
cellular protein localization GO:0034613 122 0.019
developmental process involved in reproduction GO:0003006 159 0.019
sensory perception of pain GO:0019233 73 0.019
dna metabolic process GO:0006259 96 0.019
embryonic axis specification GO:0000578 1 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
regulation of catabolic process GO:0009894 113 0.019
muscle structure development GO:0061061 87 0.019
regulation of camp metabolic process GO:0030814 43 0.019
regulation of neuron death GO:1901214 115 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
positive regulation of digestive system process GO:0060456 8 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
peptide biosynthetic process GO:0043043 3 0.018
Mouse
negative regulation of response to stimulus GO:0048585 155 0.018
negative regulation of nervous system development GO:0051961 79 0.018
response to temperature stimulus GO:0009266 94 0.018
cytoplasmic transport GO:0016482 115 0.018
innate immune response GO:0045087 35 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
serotonin receptor signaling pathway GO:0007210 10 0.018
anterior posterior pattern specification GO:0009952 1 0.018
response to toxic substance GO:0009636 133 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
neuron death GO:0070997 127 0.018
regulation of transferase activity GO:0051338 123 0.018
nucleotide biosynthetic process GO:0009165 98 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
immune response to tumor cell GO:0002418 3 0.018
negative regulation of cell communication GO:0010648 158 0.018
regulation of metal ion transport GO:0010959 118 0.018
regulation of cell motility GO:2000145 131 0.018
Rat
response to other organism GO:0051707 220 0.018
axis specification GO:0009798 4 0.018
response to acid chemical GO:0001101 222 0.017
protein localization to organelle GO:0033365 57 0.017
muscle organ development GO:0007517 50 0.017
regulation of immune response to tumor cell GO:0002837 3 0.017
positive regulation of synaptic transmission GO:0050806 62 0.017
glucose metabolic process GO:0006006 52 0.017
nucleocytoplasmic transport GO:0006913 48 0.017
cyclic purine nucleotide metabolic process GO:0052652 62 0.017
response to alkaloid GO:0043279 132 0.017
proteolysis GO:0006508 175 0.017
anion transport GO:0006820 178 0.017
embryonic skeletal system morphogenesis GO:0048704 3 0.017
cardiac muscle cell development GO:0055013 16 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
response to hexose GO:0009746 144 0.017
response to ammonium ion GO:0060359 71 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
single organism organelle organization GO:1902589 180 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
Rat
sensory organ development GO:0007423 74 0.017
nuclear transport GO:0051169 49 0.017
macromolecule catabolic process GO:0009057 58 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
regulation of anatomical structure size GO:0090066 135 0.016
response to insulin GO:0032868 133 0.016
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.016
gonad development GO:0008406 104 0.016
dendrite development GO:0016358 72 0.016
heart contraction GO:0060047 57 0.016
positive regulation of cellular catabolic process GO:0031331 71 0.016
protein complex subunit organization GO:0071822 302 0.016
cyclic nucleotide metabolic process GO:0009187 80 0.016
response to amine GO:0014075 46 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
motor neuron axon guidance GO:0008045 1 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.016
epithelial cell migration GO:0010631 19 0.016
maintenance of location GO:0051235 17 0.016
monosaccharide metabolic process GO:0005996 61 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.016
neuron projection morphogenesis GO:0048812 122 0.016
cellular response to alcohol GO:0097306 87 0.016
wound healing GO:0042060 122 0.016
small molecule biosynthetic process GO:0044283 124 0.016
protein targeting to nucleus GO:0044744 35 0.016
axonogenesis GO:0007409 71 0.016
cytokine production GO:0001816 61 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
multicellular organismal homeostasis GO:0048871 49 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
response to hydrogen peroxide GO:0042542 89 0.015
taxis GO:0042330 67 0.015
regulation of response to tumor cell GO:0002834 3 0.015

Pcsk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019