Rattus norvegicus

40 known processes

Pdcd4

programmed cell death 4

(Aliases: Dug)

Pdcd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular localization GO:0060341 263 0.228
regulation of protein metabolic process GO:0051246 289 0.190
negative regulation of cellular metabolic process GO:0031324 281 0.162
regulation of molecular function GO:0065009 398 0.140
negative regulation of metabolic process GO:0009892 331 0.136
nucleobase containing small molecule metabolic process GO:0055086 316 0.135
regulation of catalytic activity GO:0050790 304 0.124
cellular response to endogenous stimulus GO:0071495 377 0.111
catabolic process GO:0009056 351 0.108
negative regulation of macromolecule metabolic process GO:0010605 260 0.102
rna metabolic process GO:0016070 406 0.098
transcription dna templated GO:0006351 377 0.096
negative regulation of apoptotic process GO:0043066 181 0.095
macromolecule localization GO:0033036 252 0.092
macromolecular complex subunit organization GO:0043933 339 0.089
protein transport GO:0015031 132 0.088
carbohydrate metabolic process GO:0005975 130 0.088
negative regulation of gene expression GO:0010629 199 0.083
regulation of apoptotic process GO:0042981 335 0.081
apoptotic process GO:0006915 381 0.081
reproductive process GO:0022414 372 0.080
cellular catabolic process GO:0044248 295 0.078
aging GO:0007568 241 0.077
single organism cellular localization GO:1902580 102 0.077
reproduction GO:0000003 245 0.076
protein targeting GO:0006605 61 0.075
carbohydrate derivative metabolic process GO:1901135 346 0.075
rna biosynthetic process GO:0032774 380 0.074
protein phosphorylation GO:0006468 345 0.073
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.071
nucleic acid templated transcription GO:0097659 379 0.070
nitrogen compound transport GO:0071705 229 0.070
regulation of cellular protein metabolic process GO:0032268 267 0.069
neurological system process GO:0050877 219 0.069
cellular component biogenesis GO:0044085 368 0.066
intracellular protein transport GO:0006886 79 0.065
single organism nuclear import GO:1902593 35 0.064
multi organism reproductive process GO:0044703 262 0.063
protein complex assembly GO:0006461 263 0.063
intracellular signal transduction GO:0035556 314 0.062
establishment of protein localization to organelle GO:0072594 44 0.062
protein import GO:0017038 37 0.061
protein localization GO:0008104 191 0.061
regulation of protein import into nucleus GO:0042306 24 0.061
neuron differentiation GO:0030182 368 0.061
reproductive structure development GO:0048608 128 0.060
cellular protein localization GO:0034613 122 0.060
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.059
negative regulation of programmed cell death GO:0043069 183 0.058
organelle organization GO:0006996 266 0.058
nucleotide metabolic process GO:0009117 279 0.057
multicellular organism reproduction GO:0032504 233 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.056
negative regulation of biosynthetic process GO:0009890 168 0.056
purine containing compound metabolic process GO:0072521 253 0.055
protein complex subunit organization GO:0071822 302 0.055
positive regulation of gene expression GO:0010628 244 0.054
purine nucleotide metabolic process GO:0006163 229 0.054
single organism carbohydrate metabolic process GO:0044723 118 0.053
cell cycle GO:0007049 101 0.053
cellular response to organonitrogen compound GO:0071417 197 0.052
regulation of rna biosynthetic process GO:2001141 381 0.051
response to peptide hormone GO:0043434 278 0.051
response to extracellular stimulus GO:0009991 380 0.051
negative regulation of protein metabolic process GO:0051248 114 0.050
positive regulation of secretion by cell GO:1903532 128 0.049
organic acid metabolic process GO:0006082 292 0.049
negative regulation of signaling GO:0023057 157 0.049
purine nucleotide biosynthetic process GO:0006164 83 0.047
metal ion transport GO:0030001 289 0.047
purine ribonucleotide metabolic process GO:0009150 227 0.047
positive regulation of protein metabolic process GO:0051247 178 0.047
purine ribonucleoside metabolic process GO:0046128 168 0.047
regulation of nucleotide metabolic process GO:0006140 117 0.045
single organism reproductive process GO:0044702 297 0.045
regulation of rna metabolic process GO:0051252 391 0.045
cellular component assembly GO:0022607 360 0.045
purine containing compound catabolic process GO:0072523 138 0.045
regulation of intracellular signal transduction GO:1902531 218 0.045
intracellular transport GO:0046907 185 0.043
positive regulation of signaling GO:0023056 270 0.043
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.043
regulation of cellular component organization GO:0051128 368 0.043
developmental process involved in reproduction GO:0003006 159 0.043
cellular macromolecule localization GO:0070727 122 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.042
positive regulation of transport GO:0051050 245 0.042
regulation of cell proliferation GO:0042127 359 0.041
nucleoside metabolic process GO:0009116 179 0.041
cellular response to nitrogen compound GO:1901699 210 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
chemical homeostasis GO:0048878 292 0.041
programmed cell death GO:0012501 392 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
nucleocytoplasmic transport GO:0006913 48 0.040
ribonucleotide metabolic process GO:0009259 231 0.039
regulation of protein modification process GO:0031399 194 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
cation transport GO:0006812 382 0.038
peptide transport GO:0015833 97 0.038
positive regulation of molecular function GO:0044093 230 0.037
oxoacid metabolic process GO:0043436 290 0.037
regulation of establishment of protein localization GO:0070201 69 0.037
cell activation GO:0001775 97 0.037
organic substance catabolic process GO:1901575 316 0.037
sexual reproduction GO:0019953 148 0.036
response to oxygen levels GO:0070482 265 0.036
regulation of secretion by cell GO:1903530 208 0.036
ribose phosphate metabolic process GO:0019693 235 0.036
cellular response to hormone stimulus GO:0032870 247 0.036
organophosphate metabolic process GO:0019637 370 0.036
mitotic cell cycle process GO:1903047 35 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.035
cellular homeostasis GO:0019725 252 0.035
regulation of protein phosphorylation GO:0001932 183 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.034
response to hypoxia GO:0001666 231 0.034
cellular component movement GO:0006928 248 0.033
cellular response to peptide hormone stimulus GO:0071375 120 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
regulation of signal transduction GO:0009966 318 0.032
amine metabolic process GO:0009308 38 0.032
regulation of transcription dna templated GO:0006355 374 0.032
homeostatic process GO:0042592 331 0.032
organophosphate biosynthetic process GO:0090407 143 0.032
purine nucleoside metabolic process GO:0042278 169 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
cytoplasmic transport GO:0016482 115 0.032
actin filament based process GO:0030029 86 0.031
regulation of catabolic process GO:0009894 113 0.031
regulation of ion transport GO:0043269 245 0.031
cell cycle phase transition GO:0044770 21 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
vesicle mediated transport GO:0016192 181 0.031
response to decreased oxygen levels GO:0036293 237 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
regulation of programmed cell death GO:0043067 341 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
neuron projection development GO:0031175 273 0.029
alternative mrna splicing via spliceosome GO:0000380 4 0.029
localization of cell GO:0051674 202 0.029
cellular ketone metabolic process GO:0042180 51 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
translation GO:0006412 35 0.029
positive regulation of intracellular protein transport GO:0090316 20 0.028
mitotic cell cycle GO:0000278 49 0.028
single organism behavior GO:0044708 130 0.028
protein localization to organelle GO:0033365 57 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
reproductive system development GO:0061458 128 0.028
growth GO:0040007 165 0.027
hormone transport GO:0009914 121 0.027
regulation of neuron differentiation GO:0045664 208 0.027
proteolysis GO:0006508 175 0.027
purine nucleoside triphosphate metabolic process GO:0009144 141 0.027
acetate ester biosynthetic process GO:1900620 2 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
wnt signaling pathway GO:0016055 17 0.027
developmental growth GO:0048589 100 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
jak stat cascade GO:0007259 26 0.026
single organism intracellular transport GO:1902582 166 0.026
negative regulation of nucleic acid templated transcription GO:1903507 117 0.026
glycosyl compound metabolic process GO:1901657 182 0.026
response to peptide GO:1901652 292 0.025
regulation of hydrolase activity GO:0051336 143 0.025
protein oligomerization GO:0051259 191 0.025
response to temperature stimulus GO:0009266 94 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
transmembrane transport GO:0055085 412 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
response to ethanol GO:0045471 162 0.024
meiotic cell cycle process GO:1903046 3 0.024
regulation of cell differentiation GO:0045595 320 0.024
regulation of peptide hormone secretion GO:0090276 80 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
central nervous system development GO:0007417 311 0.024
macromolecular complex assembly GO:0065003 273 0.023
nucleotide catabolic process GO:0009166 139 0.023
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
signal release GO:0023061 145 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
cellular amine metabolic process GO:0044106 38 0.023
negative regulation of cell death GO:0060548 229 0.023
cellular response to peptide GO:1901653 133 0.022
cellular chemical homeostasis GO:0055082 247 0.022
single organism catabolic process GO:0044712 283 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
regulation of nucleocytoplasmic transport GO:0046822 28 0.022
organic anion transport GO:0015711 132 0.021
protein complex biogenesis GO:0070271 263 0.021
calcium ion homeostasis GO:0055074 162 0.021
response to organophosphorus GO:0046683 102 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
regulation of cell development GO:0060284 263 0.020
regulation of immune system process GO:0002682 123 0.020
ribonucleotide catabolic process GO:0009261 136 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
insulin secretion GO:0030073 69 0.020
cell cell signaling GO:0007267 335 0.020
muscle cell proliferation GO:0033002 84 0.020
cytoskeleton organization GO:0007010 111 0.020
negative regulation of cell communication GO:0010648 158 0.020
regeneration GO:0031099 163 0.020
aromatic compound catabolic process GO:0019439 168 0.020
regulation of neuron apoptotic process GO:0043523 83 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
organophosphate catabolic process GO:0046434 148 0.019
positive regulation of cell death GO:0010942 184 0.019
regulation of transferase activity GO:0051338 123 0.019
regulation of smooth muscle cell proliferation GO:0048660 75 0.019
cell type specific apoptotic process GO:0097285 134 0.019
regulation of neuron projection development GO:0010975 161 0.019
cellular response to insulin stimulus GO:0032869 81 0.019
divalent inorganic cation transport GO:0072511 134 0.019
positive regulation of intracellular transport GO:0032388 39 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
protein localization to nucleus GO:0034504 39 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.019
regulation of neurogenesis GO:0050767 247 0.018
anion transport GO:0006820 178 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
protein import into nucleus GO:0006606 35 0.018
regulation of metal ion transport GO:0010959 118 0.018
peptide hormone secretion GO:0030072 84 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
regulation of protein localization GO:0032880 81 0.018
response to purine containing compound GO:0014074 126 0.018
antral ovarian follicle growth GO:0001547 3 0.018
posttranscriptional regulation of gene expression GO:0010608 37 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
gonad development GO:0008406 104 0.018
cell projection morphogenesis GO:0048858 123 0.018
metal ion homeostasis GO:0055065 186 0.017
single organism organelle organization GO:1902589 180 0.017
response to radiation GO:0009314 137 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
secretion GO:0046903 307 0.017
regulation of secretion GO:0051046 224 0.017
regulation of nervous system development GO:0051960 264 0.017
female sex differentiation GO:0046660 59 0.017
female gonad development GO:0008585 53 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
regulation of protein kinase activity GO:0045859 105 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
guanosine containing compound catabolic process GO:1901069 71 0.017
carboxylic acid transport GO:0046942 115 0.017
gamete generation GO:0007276 124 0.017
development of primary sexual characteristics GO:0045137 107 0.017
cell projection organization GO:0030030 302 0.017
circulatory system development GO:0072359 134 0.017
positive regulation of secretion GO:0051047 140 0.017
divalent metal ion transport GO:0070838 132 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
ion transmembrane transport GO:0034220 365 0.016
heterocycle catabolic process GO:0046700 167 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
response to alkaloid GO:0043279 132 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
regulation of intracellular protein transport GO:0033157 34 0.016
regulation of intracellular transport GO:0032386 65 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
head development GO:0060322 247 0.016
positive regulation of signal transduction GO:0009967 175 0.016
multi multicellular organism process GO:0044706 138 0.016
rhythmic process GO:0048511 156 0.015
response to cytokine GO:0034097 215 0.015
regulation of translation GO:0006417 27 0.015
positive regulation of nervous system development GO:0051962 178 0.015
neuron apoptotic process GO:0051402 88 0.015
cation homeostasis GO:0055080 195 0.015
male gamete generation GO:0048232 99 0.015
mitotic cell cycle phase transition GO:0044772 20 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
brain development GO:0007420 247 0.015
regulation of homeostatic process GO:0032844 101 0.015
locomotion GO:0040011 237 0.015
response to mechanical stimulus GO:0009612 134 0.015
gland development GO:0048732 155 0.014
ureteric bud development GO:0001657 14 0.014
response to insulin GO:0032868 133 0.014
response to hexose GO:0009746 144 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
neuron death GO:0070997 127 0.014
response to oxidative stress GO:0006979 186 0.014
peptide secretion GO:0002790 86 0.014
response to corticosteroid GO:0031960 235 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.014
ion homeostasis GO:0050801 212 0.014
protein modification by small protein conjugation GO:0032446 31 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
positive regulation of cell development GO:0010720 176 0.014
mechanoreceptor differentiation GO:0042490 2 0.014
regulation of membrane potential GO:0042391 110 0.014
positive regulation of cell communication GO:0010647 271 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
response to bacterium GO:0009617 200 0.013
protein maturation GO:0051604 68 0.013
nuclear import GO:0051170 35 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
cellular ion homeostasis GO:0006873 184 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
positive regulation of ion transport GO:0043270 94 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
regulation of muscle system process GO:0090257 79 0.013
cell morphogenesis GO:0000902 142 0.013
protein processing GO:0016485 68 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
organ regeneration GO:0031100 101 0.013
nucleoside bisphosphate metabolic process GO:0033865 1 0.013
response to nutrient levels GO:0031667 370 0.013
learning or memory GO:0007611 90 0.013
regulation of cell growth GO:0001558 85 0.013
regulation of peptide transport GO:0090087 87 0.013
regulation of phosphorylation GO:0042325 248 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
sensory perception GO:0007600 101 0.013
positive regulation of catabolic process GO:0009896 78 0.013
establishment of protein localization GO:0045184 141 0.013
positive regulation of fatty acid beta oxidation GO:0032000 4 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
neuron development GO:0048666 286 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of cell migration GO:0030334 128 0.012
calcium ion transport GO:0006816 131 0.012
regulation of kinase activity GO:0043549 117 0.012
chromosome segregation GO:0007059 2 0.012
regulation of neuron death GO:1901214 115 0.012
circulatory system process GO:0003013 183 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
positive regulation of protein transport GO:0051222 41 0.012
nuclear transport GO:0051169 49 0.012
positive regulation of transcription factor import into nucleus GO:0042993 4 0.012
cellular response to stress GO:0033554 269 0.012
dendrite development GO:0016358 72 0.012
regulation of locomotion GO:0040012 148 0.012
response to inorganic substance GO:0010035 377 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
mitotic spindle organization GO:0007052 2 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
memory GO:0007613 54 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
defense response GO:0006952 194 0.012
regulation of peptide secretion GO:0002791 82 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
cell cycle process GO:0022402 57 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
rna localization GO:0006403 4 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
sex differentiation GO:0007548 113 0.012
peptidyl amino acid modification GO:0018193 126 0.012
purine nucleoside monophosphate catabolic process GO:0009128 55 0.011
negative regulation of molecular function GO:0044092 133 0.011
response to external biotic stimulus GO:0043207 221 0.011
protein catabolic process GO:0030163 30 0.011
behavior GO:0007610 205 0.011
amide transport GO:0042886 105 0.011
regulation of hormone levels GO:0010817 187 0.011
atp catabolic process GO:0006200 54 0.011
positive regulation of immune system process GO:0002684 90 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of cell projection organization GO:0031344 175 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
negative regulation of signal transduction GO:0009968 83 0.011
single organism biosynthetic process GO:0044711 342 0.011
response to growth factor GO:0070848 189 0.011
mitotic dna damage checkpoint GO:0044773 1 0.011
mesonephros development GO:0001823 14 0.011
negative regulation of protein processing GO:0010955 47 0.011
regulation of amine transport GO:0051952 54 0.011
negative regulation of transport GO:0051051 136 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 3 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.010
positive regulation of developmental process GO:0051094 283 0.010
hormone secretion GO:0046879 115 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
regulation of cell cycle arrest GO:0071156 2 0.010
regulation of system process GO:0044057 208 0.010
cell cycle checkpoint GO:0000075 2 0.010
cellular component morphogenesis GO:0032989 155 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
kidney development GO:0001822 67 0.010
lipid storage GO:0019915 1 0.010
response to ketone GO:1901654 182 0.010
cell cycle g1 s phase transition GO:0044843 13 0.010
cell motility GO:0048870 202 0.010

Pdcd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011