Rattus norvegicus

53 known processes

Pde1b

phosphodiesterase 1B, calmodulin-dependent

(Aliases: Aop2,Pde1b1)

Pde1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of secretion GO:0051046 224 0.680
Rat
cell cell signaling GO:0007267 335 0.599
Mouse Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.509
secretion GO:0046903 307 0.493
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.466
ion transmembrane transport GO:0034220 365 0.414
regulation of synaptic transmission GO:0050804 141 0.397
synaptic transmission GO:0007268 235 0.393
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.353
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.351
metal ion transport GO:0030001 289 0.332
cation transport GO:0006812 382 0.319
positive regulation of cell communication GO:0010647 271 0.301
secretion by cell GO:0032940 248 0.271
Rat
nitrogen compound transport GO:0071705 229 0.266
Rat
regulation of secretion by cell GO:1903530 208 0.259
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.248
synaptic vesicle exocytosis GO:0016079 15 0.248
blood circulation GO:0008015 183 0.243
protein complex subunit organization GO:0071822 302 0.235
regulation of membrane potential GO:0042391 110 0.203
single organism behavior GO:0044708 130 0.202
Mouse
neurotransmitter transport GO:0006836 42 0.196
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.194
neurological system process GO:0050877 219 0.179
Mouse Rat
calcium ion transport GO:0006816 131 0.174
positive regulation of secretion by cell GO:1903532 128 0.170
heart process GO:0003015 57 0.164
regulation of amine transport GO:0051952 54 0.161
positive regulation of nucleotide metabolic process GO:0045981 91 0.154
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.152
response to alkaloid GO:0043279 132 0.147
regulation of phosphorus metabolic process GO:0051174 349 0.145
monovalent inorganic cation transport GO:0015672 172 0.144
cognition GO:0050890 92 0.138
Mouse
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.137
carbohydrate derivative catabolic process GO:1901136 147 0.135
intracellular signal transduction GO:0035556 314 0.127
Rat
positive regulation of transport GO:0051050 245 0.127
positive regulation of phosphorus metabolic process GO:0010562 262 0.125
second messenger mediated signaling GO:0019932 51 0.124
Rat
organonitrogen compound catabolic process GO:1901565 179 0.123
positive regulation of phosphate metabolic process GO:0045937 262 0.122
exocytosis GO:0006887 60 0.121
potassium ion transmembrane transport GO:0071805 71 0.119
single organism membrane organization GO:0044802 74 0.116
divalent inorganic cation transport GO:0072511 134 0.116
regulation of neurotransmitter secretion GO:0046928 19 0.115
mapk cascade GO:0000165 140 0.115
transmembrane transport GO:0055085 412 0.115
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 10 0.115
behavior GO:0007610 205 0.111
Mouse
synaptic vesicle localization GO:0097479 24 0.110
neurotransmitter secretion GO:0007269 33 0.107
sodium ion transmembrane transport GO:0035725 67 0.107
muscle system process GO:0003012 115 0.107
learning or memory GO:0007611 90 0.107
Mouse
circulatory system process GO:0003013 183 0.107
regulation of neurotransmitter levels GO:0001505 42 0.105
Mouse
camp metabolic process GO:0046058 63 0.105
regulation of cellular localization GO:0060341 263 0.104
Rat
regulation of cell development GO:0060284 263 0.104
positive regulation of cyclase activity GO:0031281 15 0.104
calcium ion homeostasis GO:0055074 162 0.102
signal release GO:0023061 145 0.102
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.101
purine ribonucleotide metabolic process GO:0009150 227 0.099
regulation of cyclase activity GO:0031279 21 0.097
muscle contraction GO:0006936 88 0.095
inorganic cation transmembrane transport GO:0098662 202 0.094
positive regulation of phosphorylation GO:0042327 177 0.093
neuromuscular synaptic transmission GO:0007274 2 0.093
purine nucleotide metabolic process GO:0006163 229 0.092
cation transmembrane transport GO:0098655 263 0.092
cellular homeostasis GO:0019725 252 0.090
negative regulation of cell communication GO:0010648 158 0.090
Rat
positive regulation of molecular function GO:0044093 230 0.089
regulation of phosphate metabolic process GO:0019220 349 0.087
negative adaptation of signaling pathway GO:0022401 10 0.086
negative regulation of response to stimulus GO:0048585 155 0.085
l glutamate import GO:0051938 2 0.082
positive regulation of multicellular organismal process GO:0051240 387 0.082
divalent metal ion transport GO:0070838 132 0.081
sensory perception GO:0007600 101 0.081
Rat
eating behavior GO:0042755 21 0.080
regulation of synaptic plasticity GO:0048167 70 0.080
organophosphate catabolic process GO:0046434 148 0.080
membrane organization GO:0061024 94 0.080
regulation of purine nucleotide metabolic process GO:1900542 115 0.079
regulation of synaptic transmission glutamatergic GO:0051966 26 0.079
regulation of multicellular organismal development GO:2000026 376 0.079
signal transduction by phosphorylation GO:0023014 144 0.078
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.078
regulation of ion transport GO:0043269 245 0.078
ribonucleotide metabolic process GO:0009259 231 0.077
regulation of system process GO:0044057 208 0.076
positive regulation of hydrolase activity GO:0051345 86 0.076
ribonucleotide catabolic process GO:0009261 136 0.074
vesicle mediated transport GO:0016192 181 0.074
neurotransmitter gated ion channel clustering GO:0072578 3 0.074
positive regulation of catalytic activity GO:0043085 184 0.074
purine containing compound metabolic process GO:0072521 253 0.074
regulation of catecholamine secretion GO:0050433 32 0.073
regulation of intracellular signal transduction GO:1902531 218 0.071
regulation of cellular protein metabolic process GO:0032268 267 0.071
positive regulation of intracellular signal transduction GO:1902533 138 0.071
regulation of adenylate cyclase activity GO:0045761 18 0.070
transmission of nerve impulse GO:0019226 42 0.067
regulation of ion transmembrane transporter activity GO:0032412 48 0.067
ribonucleoside triphosphate metabolic process GO:0009199 141 0.067
cellular component biogenesis GO:0044085 368 0.067
purine ribonucleotide catabolic process GO:0009154 136 0.066
ribonucleoside triphosphate catabolic process GO:0009203 122 0.065
regulation of signal transduction GO:0009966 318 0.064
ribose phosphate biosynthetic process GO:0046390 87 0.064
regulation of lyase activity GO:0051339 22 0.064
purine nucleoside triphosphate catabolic process GO:0009146 122 0.063
nucleobase containing small molecule metabolic process GO:0055086 316 0.063
anion transport GO:0006820 178 0.063
negative regulation of signaling GO:0023057 157 0.063
Rat
synaptic transmission glutamatergic GO:0035249 33 0.063
detection of stimulus GO:0051606 24 0.062
smooth muscle contraction GO:0006939 37 0.061
synaptic transmission gabaergic GO:0051932 22 0.059
positive regulation of ion transport GO:0043270 94 0.058
regulation of exocytosis GO:0017157 37 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.057
purine nucleoside triphosphate metabolic process GO:0009144 141 0.057
glycosyl compound catabolic process GO:1901658 126 0.056
nucleoside phosphate metabolic process GO:0006753 283 0.056
purine nucleotide catabolic process GO:0006195 136 0.056
potassium ion transport GO:0006813 97 0.055
adaptation of signaling pathway GO:0023058 10 0.055
positive regulation of amine transport GO:0051954 26 0.055
cellular divalent inorganic cation homeostasis GO:0072503 162 0.055
positive regulation of cellular protein metabolic process GO:0032270 167 0.054
regulation of mapk cascade GO:0043408 116 0.054
positive regulation of response to stimulus GO:0048584 285 0.054
inorganic ion transmembrane transport GO:0098660 229 0.054
cellular component assembly GO:0022607 360 0.053
regulation of vesicle mediated transport GO:0060627 81 0.052
positive regulation of nucleoside metabolic process GO:0045979 55 0.051
cellular ion homeostasis GO:0006873 184 0.051
vascular process in circulatory system GO:0003018 96 0.051
organophosphate metabolic process GO:0019637 370 0.051
sodium ion transport GO:0006814 82 0.050
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.050
regulation of synaptic vesicle exocytosis GO:2000300 6 0.050
regulation of nucleotide metabolic process GO:0006140 117 0.050
ribose phosphate metabolic process GO:0019693 235 0.050
ribonucleoside catabolic process GO:0042454 126 0.050
amine transport GO:0015837 57 0.050
purine ribonucleoside metabolic process GO:0046128 168 0.050
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.048
monoamine transport GO:0015844 43 0.048
protein complex biogenesis GO:0070271 263 0.048
purine ribonucleotide biosynthetic process GO:0009152 81 0.048
response to ammonium ion GO:0060359 71 0.048
chemical homeostasis GO:0048878 292 0.047
homeostatic process GO:0042592 331 0.047
positive regulation of secretion GO:0051047 140 0.047
aromatic compound catabolic process GO:0019439 168 0.047
positive regulation of signal transduction GO:0009967 175 0.047
rhythmic synaptic transmission GO:0060024 1 0.046
respiratory gaseous exchange GO:0007585 4 0.046
purine nucleoside catabolic process GO:0006152 124 0.046
regulation of calcium ion transport GO:0051924 77 0.046
positive regulation of synaptic transmission GO:0050806 62 0.045
positive regulation of signaling GO:0023056 270 0.045
nucleoside triphosphate metabolic process GO:0009141 144 0.045
regulation of synaptic transmission gabaergic GO:0032228 17 0.045
nucleoside metabolic process GO:0009116 179 0.045
protein localization GO:0008104 191 0.045
nucleoside catabolic process GO:0009164 126 0.044
ribonucleotide biosynthetic process GO:0009260 85 0.044
regulation of heart contraction GO:0008016 48 0.044
ribonucleoside metabolic process GO:0009119 174 0.044
cation homeostasis GO:0055080 195 0.044
nucleoside phosphate biosynthetic process GO:1901293 102 0.043
cyclic nucleotide biosynthetic process GO:0009190 63 0.043
divalent inorganic cation homeostasis GO:0072507 165 0.042
nucleotide metabolic process GO:0009117 279 0.042
regulation of neurotransmitter transport GO:0051588 21 0.041
positive regulation of long term synaptic potentiation GO:1900273 4 0.041
neuron neuron synaptic transmission GO:0007270 60 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.040
positive regulation of adenylate cyclase activity GO:0045762 12 0.040
positive regulation of exocytosis GO:0045921 19 0.040
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.040
phosphatidylinositol dephosphorylation GO:0046856 4 0.040
regulation of purine nucleotide catabolic process GO:0033121 65 0.039
regulation of cell activation GO:0050865 50 0.039
purine containing compound biosynthetic process GO:0072522 85 0.039
synaptic vesicle transport GO:0048489 23 0.039
negative regulation of response to external stimulus GO:0032102 37 0.038
regulation of molecular function GO:0065009 398 0.038
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 5 0.038
cellular calcium ion homeostasis GO:0006874 160 0.038
organic substance catabolic process GO:1901575 316 0.038
protein oligomerization GO:0051259 191 0.038
tonic smooth muscle contraction GO:0014820 4 0.038
cyclic purine nucleotide metabolic process GO:0052652 62 0.037
positive regulation of gamma aminobutyric acid secretion GO:0014054 4 0.037
regulation of postsynaptic membrane potential GO:0060078 25 0.036
ion homeostasis GO:0050801 212 0.036
amino acid transport GO:0006865 70 0.036
glutamate receptor signaling pathway GO:0007215 43 0.035
negative regulation of defecation GO:2000293 1 0.035
macromolecule localization GO:0033036 252 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.035
anion transmembrane transport GO:0098656 77 0.035
cellular nitrogen compound catabolic process GO:0044270 163 0.035
regulation of anion transport GO:0044070 43 0.035
organophosphate biosynthetic process GO:0090407 143 0.035
regulation of synaptic vesicle transport GO:1902803 6 0.034
metal ion homeostasis GO:0055065 186 0.034
heart contraction GO:0060047 57 0.034
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.034
regulation of cellular component organization GO:0051128 368 0.034
sensory perception of pain GO:0019233 73 0.034
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.034
catabolic process GO:0009056 351 0.033
regulation of blood vessel size GO:0050880 89 0.033
brain development GO:0007420 247 0.033
respiratory system process GO:0003016 3 0.033
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 2 0.033
regulation of hormone secretion GO:0046883 106 0.033
Rat
positive regulation of nucleotide catabolic process GO:0030813 53 0.032
regulation of anatomical structure size GO:0090066 135 0.032
purine nucleoside metabolic process GO:0042278 169 0.032
regulation of camp metabolic process GO:0030814 43 0.031
protein phosphorylation GO:0006468 345 0.030
regulation of neurogenesis GO:0050767 247 0.030
regulation of peptide transport GO:0090087 87 0.030
Rat
cellular chemical homeostasis GO:0055082 247 0.030
artery smooth muscle contraction GO:0014824 4 0.030
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.030
regulation of muscle contraction GO:0006937 53 0.030
catecholamine transport GO:0051937 37 0.030
regulation of phosphorylation GO:0042325 248 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
synaptic vesicle endocytosis GO:0048488 4 0.029
action potential GO:0001508 54 0.029
nucleic acid templated transcription GO:0097659 379 0.029
regulation of transporter activity GO:0032409 50 0.029
purine ribonucleoside catabolic process GO:0046130 124 0.029
positive regulation of cell development GO:0010720 176 0.029
cellular catabolic process GO:0044248 295 0.029
positive regulation of blood circulation GO:1903524 65 0.029
long term synaptic potentiation GO:0060291 21 0.029
neuron projection development GO:0031175 273 0.029
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
glycosyl compound metabolic process GO:1901657 182 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
regulation of apoptotic process GO:0042981 335 0.028
regulation of nervous system development GO:0051960 264 0.028
nucleotide catabolic process GO:0009166 139 0.028
regulation of tube size GO:0035150 89 0.028
response to metal ion GO:0010038 253 0.028
Rat
organic cyclic compound catabolic process GO:1901361 175 0.027
positive regulation of catabolic process GO:0009896 78 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
nucleoside phosphate catabolic process GO:1901292 140 0.027
nucleobase containing compound catabolic process GO:0034655 152 0.027
regulation of nucleotide catabolic process GO:0030811 65 0.027
regulation of transcription dna templated GO:0006355 374 0.026
transcription dna templated GO:0006351 377 0.026
urinary bladder smooth muscle contraction GO:0014832 4 0.026
response to cgmp GO:0070305 3 0.026
establishment of vesicle localization GO:0051650 31 0.026
erk1 and erk2 cascade GO:0070371 48 0.026
negative regulation of cell proliferation GO:0008285 119 0.025
neuron development GO:0048666 286 0.025
negative regulation of response to wounding GO:1903035 23 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.025
positive regulation of mapk cascade GO:0043410 92 0.025
glutamate secretion GO:0014047 19 0.025
aging GO:0007568 241 0.025
cellular potassium ion transport GO:0071804 72 0.025
regulation of protein metabolic process GO:0051246 289 0.025
n methyl d aspartate receptor clustering GO:0097114 2 0.025
multicellular organism growth GO:0035264 1 0.025
saliva secretion GO:0046541 3 0.025
cellular amine metabolic process GO:0044106 38 0.025
Mouse
cytosolic calcium ion homeostasis GO:0051480 140 0.025
regulation of behavior GO:0050795 61 0.024
macromolecular complex assembly GO:0065003 273 0.024
regulation of inflammatory response GO:0050727 48 0.024
defense response GO:0006952 194 0.024
nucleotide biosynthetic process GO:0009165 98 0.024
calcium mediated signaling GO:0019722 23 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
intracellular transport GO:0046907 185 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
small molecule biosynthetic process GO:0044283 124 0.023
response to corticosteroid GO:0031960 235 0.023
serotonin receptor signaling pathway GO:0007210 10 0.023
purine containing compound catabolic process GO:0072523 138 0.023
response to mechanical stimulus GO:0009612 134 0.023
guanosine containing compound metabolic process GO:1901068 74 0.023
synapse organization GO:0050808 46 0.023
cellular cation homeostasis GO:0030003 180 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
positive regulation of protein kinase activity GO:0045860 73 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
Mouse
positive regulation of organic acid transport GO:0032892 22 0.022
regulation of camp biosynthetic process GO:0030817 38 0.022
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.022
purine nucleotide biosynthetic process GO:0006164 83 0.022
gtp metabolic process GO:0046039 72 0.022
phototransduction visible light GO:0007603 2 0.022
asymmetric protein localization GO:0008105 2 0.022
response to cocaine GO:0042220 39 0.022
ras protein signal transduction GO:0007265 29 0.022
memory GO:0007613 54 0.022
detection of external stimulus GO:0009581 13 0.021
positive regulation of renin secretion into blood stream GO:1900135 1 0.021
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.021
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.021
positive regulation of protein modification process GO:0031401 142 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
regulation of metal ion transport GO:0010959 118 0.021
carboxylic acid transport GO:0046942 115 0.021
cellular response to lipid GO:0071396 201 0.021
organic anion transport GO:0015711 132 0.021
neuromuscular process GO:0050905 2 0.021
positive regulation of developmental process GO:0051094 283 0.021
axis specification GO:0009798 4 0.021
prepulse inhibition GO:0060134 1 0.021
positive regulation of neurogenesis GO:0050769 165 0.020
endomembrane system organization GO:0010256 48 0.020
single organism organelle organization GO:1902589 180 0.020
protein transport GO:0015031 132 0.020
organelle organization GO:0006996 266 0.020
regulation of respiratory system process GO:0044065 1 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
regulation of protein modification process GO:0031399 194 0.020
response to histamine GO:0034776 3 0.020
single organism cellular localization GO:1902580 102 0.020
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
positive regulation of serotonin secretion GO:0014064 1 0.020
g protein coupled acetylcholine receptor signaling pathway GO:0007213 5 0.020
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.020
regulation of cell differentiation GO:0045595 320 0.020
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.019
camp biosynthetic process GO:0006171 47 0.019
protein heterooligomerization GO:0051291 89 0.019
regulation of blood circulation GO:1903522 110 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
rna metabolic process GO:0016070 406 0.019
regulation of neuronal synaptic plasticity GO:0048168 31 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
cellular response to corticosteroid stimulus GO:0071384 69 0.019
multicellular organismal signaling GO:0035637 44 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
locomotion GO:0040011 237 0.019
regulation of nucleoside metabolic process GO:0009118 66 0.019
regulation of catalytic activity GO:0050790 304 0.019
embryonic pattern specification GO:0009880 1 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of response to stress GO:0080134 126 0.019
regulation of cell proliferation GO:0042127 359 0.019
peptide secretion GO:0002790 86 0.018
Rat
rna biosynthetic process GO:0032774 380 0.018
response to growth factor GO:0070848 189 0.018
negative regulation of secretion GO:0051048 82 0.018
Rat
regulation of long term synaptic potentiation GO:1900271 5 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
visual learning GO:0008542 8 0.018
Mouse
positive regulation of cellular component organization GO:0051130 200 0.018
calcium ion dependent exocytosis of neurotransmitter GO:0048791 2 0.018
regulation of transmembrane transporter activity GO:0022898 49 0.018
single organism catabolic process GO:0044712 283 0.018
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.018
heterocycle catabolic process GO:0046700 167 0.017
organic acid metabolic process GO:0006082 292 0.017
regulation of hydrolase activity GO:0051336 143 0.017
triglyceride homeostasis GO:0070328 2 0.017
positive regulation of nervous system development GO:0051962 178 0.017
positive regulation of gtp catabolic process GO:0033126 48 0.017
establishment of protein localization GO:0045184 141 0.017
cellular protein localization GO:0034613 122 0.017
amino acid transmembrane transport GO:0003333 33 0.017
positive regulation of heart contraction GO:0045823 15 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
regulation of peptide secretion GO:0002791 82 0.017
Rat
endoplasmic reticulum membrane organization GO:0090158 1 0.017
positive regulation of camp metabolic process GO:0030816 31 0.017
detection of calcium ion GO:0005513 1 0.017
negative regulation of circadian sleep wake cycle sleep GO:0042321 5 0.017
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010578 2 0.017
gtp catabolic process GO:0006184 71 0.017
positive regulation of transferase activity GO:0051347 81 0.017
macrophage chemotaxis GO:0048246 2 0.016
regulation of renin secretion into blood stream GO:1900133 1 0.016
central nervous system development GO:0007417 311 0.016
detection of visible light GO:0009584 3 0.016
reproduction GO:0000003 245 0.016
somatostatin receptor signaling pathway GO:0038169 4 0.016
negative regulation of secretion by cell GO:1903531 72 0.016
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.016
single organism intracellular transport GO:1902582 166 0.016
hormone transport GO:0009914 121 0.016
Rat
immune system process GO:0002376 204 0.016
Human
protein complex assembly GO:0006461 263 0.016
peptide hormone secretion GO:0030072 84 0.016
Rat
organelle localization GO:0051640 55 0.016
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.015
response to cytokine GO:0034097 215 0.015
Human
regulation of sensory perception of pain GO:0051930 29 0.015
regulation of saliva secretion GO:0046877 3 0.015
regulation of nucleotide biosynthetic process GO:0030808 47 0.015
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.015
negative regulation of ion transport GO:0043271 51 0.015
regulation of rna metabolic process GO:0051252 391 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.015
response to oxygen levels GO:0070482 265 0.015
guanosine containing compound catabolic process GO:1901069 71 0.015
negative regulation of amine transport GO:0051953 24 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.015
myeloid leukocyte activation GO:0002274 36 0.015
ossification GO:0001503 70 0.015
response to camp GO:0051591 91 0.015
cell projection organization GO:0030030 302 0.015
reproductive process GO:0022414 372 0.014
positive regulation of gtpase activity GO:0043547 47 0.014
single organism biosynthetic process GO:0044711 342 0.014
regulation of immune system process GO:0002682 123 0.014
amide transport GO:0042886 105 0.014
Rat
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of response to wounding GO:1903034 69 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
acid secretion GO:0046717 48 0.014
calcium ion transmembrane transport GO:0070588 70 0.014
cell activation GO:0001775 97 0.014
response to monosaccharide GO:0034284 159 0.014
regulation of muscle system process GO:0090257 79 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
regulation of gtp catabolic process GO:0033124 58 0.014
response to hexose GO:0009746 144 0.014
regulation of kinase activity GO:0043549 117 0.014
regulation of organic acid transport GO:0032890 35 0.014
sensory perception of mechanical stimulus GO:0050954 17 0.014
dopamine transport GO:0015872 18 0.014
hormone secretion GO:0046879 115 0.014
Rat
negative regulation of vesicle fusion GO:0031339 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of lyase activity GO:0051349 15 0.014
striated muscle contraction GO:0006941 44 0.014
multicellular organism reproduction GO:0032504 233 0.014
neurotransmitter uptake GO:0001504 3 0.013
regulation of sensory perception GO:0051931 29 0.013
somatostatin signaling pathway GO:0038170 4 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
regulation of vasculature development GO:1901342 44 0.013
regulation of insulin secretion GO:0050796 65 0.013
Rat
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.013
behavioral response to cocaine GO:0048148 6 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
cellular macromolecule localization GO:0070727 122 0.013
negative regulation of synaptic transmission gabaergic GO:0032229 6 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
endoplasmic reticulum organization GO:0007029 1 0.013
negative regulation of synaptic transmission dopaminergic GO:0032227 4 0.013
neuron differentiation GO:0030182 368 0.013
negative regulation of transport GO:0051051 136 0.013
Rat
cellular carbohydrate metabolic process GO:0044262 72 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.012
blood vessel morphogenesis GO:0048514 58 0.012
regulation of cell growth GO:0001558 85 0.012
catecholamine secretion GO:0050432 33 0.012
positive regulation of protein transport GO:0051222 41 0.012
forebrain development GO:0030900 98 0.012
regulation of defense response GO:0031347 68 0.012
regulation of cell projection organization GO:0031344 175 0.012
regulation of neuron differentiation GO:0045664 208 0.012
kidney development GO:0001822 67 0.012
positive regulation of camp biosynthetic process GO:0030819 28 0.012
positive regulation of gene expression GO:0010628 244 0.012
positive regulation of smooth muscle contraction GO:0045987 18 0.012
positive regulation of neurotransmitter secretion GO:0001956 9 0.012

Pde1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
eye and adnexa disease DOID:1492 0 0.034
eye disease DOID:5614 0 0.034
retinal disease DOID:5679 0 0.034
sensory system disease DOID:0050155 0 0.034
epilepsy syndrome DOID:1826 0 0.026
central nervous system disease DOID:331 0 0.026
brain disease DOID:936 0 0.026
substance related disorder DOID:303 0 0.021
disease of mental health DOID:150 0 0.021
substance dependence DOID:9973 0 0.021