Rattus norvegicus

102 known processes

Pde4c

phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)

(Aliases: Dpde1,MGC188426)

Pde4c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.174
Rat
positive regulation of signaling GO:0023056 270 0.127
positive regulation of multicellular organismal process GO:0051240 387 0.109
tissue development GO:0009888 252 0.096
secretion by cell GO:0032940 248 0.082
response to monosaccharide GO:0034284 159 0.082
anatomical structure morphogenesis GO:0009653 298 0.079
Fly
response to carbohydrate GO:0009743 183 0.073
cell cell signaling GO:0007267 335 0.068
cation transport GO:0006812 382 0.067
nitrogen compound transport GO:0071705 229 0.066
organic acid metabolic process GO:0006082 292 0.065
single organism behavior GO:0044708 130 0.065
Fly
regulation of secretion by cell GO:1903530 208 0.064
negative regulation of cell death GO:0060548 229 0.064
cellular component movement GO:0006928 248 0.063
positive regulation of cell communication GO:0010647 271 0.062
regulation of phosphorus metabolic process GO:0051174 349 0.061
response to biotic stimulus GO:0009607 226 0.061
regulation of cellular localization GO:0060341 263 0.061
behavior GO:0007610 205 0.060
Fly
regulation of phosphate metabolic process GO:0019220 349 0.060
regulation of protein metabolic process GO:0051246 289 0.058
response to molecule of bacterial origin GO:0002237 194 0.057
positive regulation of transport GO:0051050 245 0.056
regulation of molecular function GO:0065009 398 0.056
carboxylic acid metabolic process GO:0019752 289 0.054
response to hypoxia GO:0001666 231 0.054
regulation of system process GO:0044057 208 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
nucleic acid templated transcription GO:0097659 379 0.053
lymphoid progenitor cell differentiation GO:0002320 2 0.052
regulation of rna metabolic process GO:0051252 391 0.052
protein phosphorylation GO:0006468 345 0.052
response to bacterium GO:0009617 200 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.052
response to nutrient levels GO:0031667 370 0.052
aging GO:0007568 241 0.052
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
central nervous system development GO:0007417 311 0.050
rna biosynthetic process GO:0032774 380 0.049
cellular response to oxygen containing compound GO:1901701 386 0.049
transcription dna templated GO:0006351 377 0.049
amine metabolic process GO:0009308 38 0.049
programmed cell death GO:0012501 392 0.048
response to nutrient GO:0007584 248 0.048
oxidation reduction process GO:0055114 304 0.048
secretion GO:0046903 307 0.047
regulation of cellular protein metabolic process GO:0032268 267 0.046
response to mechanical stimulus GO:0009612 134 0.045
positive regulation of biosynthetic process GO:0009891 319 0.045
homeostatic process GO:0042592 331 0.045
cellular amine metabolic process GO:0044106 38 0.044
positive regulation of intracellular signal transduction GO:1902533 138 0.044
response to cytokine GO:0034097 215 0.043
neuron differentiation GO:0030182 368 0.043
Fly
cellular response to endogenous stimulus GO:0071495 377 0.043
hormone transport GO:0009914 121 0.043
oxoacid metabolic process GO:0043436 290 0.042
cellular amino acid metabolic process GO:0006520 107 0.041
response to decreased oxygen levels GO:0036293 237 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.039
signal release GO:0023061 145 0.039
response to hexose GO:0009746 144 0.039
regulation of intracellular signal transduction GO:1902531 218 0.038
Fly
regulation of hormone levels GO:0010817 187 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
cellular homeostasis GO:0019725 252 0.037
response to other organism GO:0051707 220 0.036
heart morphogenesis GO:0003007 3 0.036
positive regulation of phosphate metabolic process GO:0045937 262 0.036
macromolecule localization GO:0033036 252 0.035
response to extracellular stimulus GO:0009991 380 0.035
blood circulation GO:0008015 183 0.035
lipid metabolic process GO:0006629 283 0.035
circulatory system process GO:0003013 183 0.035
inorganic ion transmembrane transport GO:0098660 229 0.035
reproductive process GO:0022414 372 0.035
single organism biosynthetic process GO:0044711 342 0.034
intracellular signal transduction GO:0035556 314 0.034
Rat Fly
positive regulation of molecular function GO:0044093 230 0.034
organophosphate metabolic process GO:0019637 370 0.033
regulation of programmed cell death GO:0043067 341 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.032
apoptotic process GO:0006915 381 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
regulation of apoptotic process GO:0042981 335 0.032
regulation of secretion GO:0051046 224 0.032
response to lipopolysaccharide GO:0032496 191 0.032
purine nucleotide metabolic process GO:0006163 229 0.032
neuron projection morphogenesis GO:0048812 122 0.032
Fly
cellular catabolic process GO:0044248 295 0.031
protein complex biogenesis GO:0070271 263 0.031
response to oxygen levels GO:0070482 265 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
g protein coupled receptor signaling pathway GO:0007186 242 0.031
regulation of transcription dna templated GO:0006355 374 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
neurological system process GO:0050877 219 0.030
Rat Fly
response to wounding GO:0009611 254 0.030
response to peptide GO:1901652 292 0.030
peptide transport GO:0015833 97 0.030
cellular ketone metabolic process GO:0042180 51 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
organophosphate biosynthetic process GO:0090407 143 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
amide transport GO:0042886 105 0.030
nucleotide metabolic process GO:0009117 279 0.030
positive regulation of secretion GO:0051047 140 0.030
catabolic process GO:0009056 351 0.030
reactive oxygen species metabolic process GO:0072593 37 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.029
response to growth factor GO:0070848 189 0.029
regulation of ion transport GO:0043269 245 0.029
regulation of hormone secretion GO:0046883 106 0.029
cyclic nucleotide metabolic process GO:0009187 80 0.029
positive regulation of gene expression GO:0010628 244 0.029
neuron projection development GO:0031175 273 0.029
Fly
cellular response to organic cyclic compound GO:0071407 202 0.028
multicellular organism reproduction GO:0032504 233 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
negative regulation of transport GO:0051051 136 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
multi organism reproductive process GO:0044703 262 0.028
response to external biotic stimulus GO:0043207 221 0.028
inorganic cation transmembrane transport GO:0098662 202 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
macromolecular complex assembly GO:0065003 273 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
muscle system process GO:0003012 115 0.027
positive regulation of cell migration GO:0030335 96 0.027
regulation of blood pressure GO:0008217 83 0.027
response to peptide hormone GO:0043434 278 0.027
metal ion transport GO:0030001 289 0.027
epithelial cell differentiation GO:0030855 71 0.027
cellular component assembly GO:0022607 360 0.027
cell motility GO:0048870 202 0.027
positive regulation of ion transport GO:0043270 94 0.026
cellular component biogenesis GO:0044085 368 0.026
purine containing compound metabolic process GO:0072521 253 0.026
ion transmembrane transport GO:0034220 365 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
rna metabolic process GO:0016070 406 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
positive regulation of cell development GO:0010720 176 0.026
cellular response to abiotic stimulus GO:0071214 85 0.026
negative regulation of secretion GO:0051048 82 0.026
regulation of catalytic activity GO:0050790 304 0.026
calcium ion homeostasis GO:0055074 162 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
organic substance catabolic process GO:1901575 316 0.026
chemical homeostasis GO:0048878 292 0.025
neuron fate commitment GO:0048663 4 0.025
negative regulation of secretion by cell GO:1903531 72 0.025
regulation of peptide hormone secretion GO:0090276 80 0.025
cellular lipid metabolic process GO:0044255 208 0.025
monovalent inorganic cation transport GO:0015672 172 0.025
regulation of peptide secretion GO:0002791 82 0.025
sexual reproduction GO:0019953 148 0.024
regulation of neurogenesis GO:0050767 247 0.024
locomotion GO:0040011 237 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
response to alkaloid GO:0043279 132 0.024
cellular response to cytokine stimulus GO:0071345 127 0.024
neuromuscular process GO:0050905 2 0.024
response to vitamin GO:0033273 131 0.024
protein localization GO:0008104 191 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.024
regulation of cell differentiation GO:0045595 320 0.024
regulation of cell proliferation GO:0042127 359 0.023
response to acid chemical GO:0001101 222 0.023
cell morphogenesis GO:0000902 142 0.023
Fly
ribose phosphate metabolic process GO:0019693 235 0.023
cell part morphogenesis GO:0032990 123 0.023
Fly
regulation of peptide transport GO:0090087 87 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
positive regulation of developmental process GO:0051094 283 0.023
cellular chemical homeostasis GO:0055082 247 0.023
regulation of locomotion GO:0040012 148 0.023
positive regulation of cell death GO:0010942 184 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
regulation of blood vessel size GO:0050880 89 0.023
cyclic purine nucleotide metabolic process GO:0052652 62 0.022
response to calcium ion GO:0051592 59 0.022
Rat
hormone secretion GO:0046879 115 0.022
reproduction GO:0000003 245 0.022
regulation of protein modification process GO:0031399 194 0.022
regulation of phosphorylation GO:0042325 248 0.022
neuron development GO:0048666 286 0.022
Fly
protein transport GO:0015031 132 0.022
gamete generation GO:0007276 124 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
Fly
response to corticosteroid GO:0031960 235 0.022
synaptic transmission GO:0007268 235 0.022
Fly
learning or memory GO:0007611 90 0.022
Fly
cell projection organization GO:0030030 302 0.022
Fly
cellular response to lipid GO:0071396 201 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
gastrulation GO:0007369 2 0.021
cellular macromolecule localization GO:0070727 122 0.021
lipid biosynthetic process GO:0008610 128 0.021
divalent inorganic cation transport GO:0072511 134 0.021
purine ribonucleotide biosynthetic process GO:0009152 81 0.021
regulation of cell projection organization GO:0031344 175 0.021
protein complex assembly GO:0006461 263 0.021
multi multicellular organism process GO:0044706 138 0.021
cellular component morphogenesis GO:0032989 155 0.020
Fly
regulation of synaptic transmission GO:0050804 141 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
cellular ion homeostasis GO:0006873 184 0.020
camp metabolic process GO:0046058 63 0.020
ion homeostasis GO:0050801 212 0.020
regulation of protein localization GO:0032880 81 0.020
single organism reproductive process GO:0044702 297 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
biological adhesion GO:0022610 110 0.020
carbohydrate metabolic process GO:0005975 130 0.020
response to glucocorticoid GO:0051384 223 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of cell communication GO:0010648 158 0.019
developmental process involved in reproduction GO:0003006 159 0.019
response to transforming growth factor beta GO:0071559 46 0.019
sensory organ development GO:0007423 74 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
regulation of cellular component organization GO:0051128 368 0.019
transmembrane transport GO:0055085 412 0.019
regulation of cell development GO:0060284 263 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
peptidyl amino acid modification GO:0018193 126 0.019
rhythmic process GO:0048511 156 0.019
regulation of signal transduction GO:0009966 318 0.019
Fly
regulation of neuron differentiation GO:0045664 208 0.019
development of primary sexual characteristics GO:0045137 107 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
cell growth GO:0016049 104 0.018
Fly
striated muscle tissue development GO:0014706 58 0.018
cell projection morphogenesis GO:0048858 123 0.018
Fly
positive regulation of nervous system development GO:0051962 178 0.018
response to glucose GO:0009749 136 0.018
response to inorganic substance GO:0010035 377 0.018
Rat
circulatory system development GO:0072359 134 0.018
cellular response to external stimulus GO:0071496 118 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
insulin secretion GO:0030073 69 0.018
response to radiation GO:0009314 137 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
regulation of insulin secretion GO:0050796 65 0.018
head development GO:0060322 247 0.018
axonogenesis GO:0007409 71 0.018
Fly
endocrine system development GO:0035270 30 0.018
anion transport GO:0006820 178 0.017
cellular response to acid chemical GO:0071229 75 0.017
cellular response to metal ion GO:0071248 55 0.017
negative regulation of signaling GO:0023057 157 0.017
regulation of calcium ion transport GO:0051924 77 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
gliogenesis GO:0042063 93 0.017
regulation of cell migration GO:0030334 128 0.017
regulation of cell motility GO:2000145 131 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
cell migration GO:0016477 197 0.017
developmental growth GO:0048589 100 0.017
Fly
negative regulation of multicellular organismal process GO:0051241 203 0.017
cyclic nucleotide biosynthetic process GO:0009190 63 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
regulation of synaptic plasticity GO:0048167 70 0.016
single organism intracellular transport GO:1902582 166 0.016
intracellular transport GO:0046907 185 0.016
response to tumor necrosis factor GO:0034612 56 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
sex differentiation GO:0007548 113 0.016
peptide secretion GO:0002790 86 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
response to estrogen GO:0043627 232 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
muscle tissue development GO:0060537 58 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.016
cognition GO:0050890 92 0.016
Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
negative regulation of metabolic process GO:0009892 331 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
axis specification GO:0009798 4 0.016
response to oxidative stress GO:0006979 186 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
Fly
response to ethanol GO:0045471 162 0.015
muscle structure development GO:0061061 87 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
action potential GO:0001508 54 0.015
anterior posterior pattern specification GO:0009952 1 0.015
negative regulation of peptide hormone secretion GO:0090278 30 0.015
positive regulation of signal transduction GO:0009967 175 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
negative regulation of molecular function GO:0044092 133 0.015
multicellular organism growth GO:0035264 1 0.015
protein maturation GO:0051604 68 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
cellular protein localization GO:0034613 122 0.015
response to dexamethasone GO:0071548 49 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.015
peptide hormone secretion GO:0030072 84 0.015
localization of cell GO:0051674 202 0.015
female pregnancy GO:0007565 122 0.015
mesoderm development GO:0007498 2 0.015
cellular response to mechanical stimulus GO:0071260 48 0.015
regulation of nervous system development GO:0051960 264 0.015
reproductive system development GO:0061458 128 0.015
second messenger mediated signaling GO:0019932 51 0.015
Rat
proteolysis GO:0006508 175 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
heart contraction GO:0060047 57 0.014
protein oligomerization GO:0051259 191 0.014
maintenance of location GO:0051235 17 0.014
forebrain development GO:0030900 98 0.014
regulation of hydrolase activity GO:0051336 143 0.014
organic acid transport GO:0015849 116 0.014
chemotaxis GO:0006935 66 0.014
muscle organ development GO:0007517 50 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
establishment of protein localization GO:0045184 141 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
small molecule catabolic process GO:0044282 59 0.014
response to ketone GO:1901654 182 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
growth GO:0040007 165 0.014
Fly
negative regulation of gene expression GO:0010629 199 0.014
formation of primary germ layer GO:0001704 1 0.014
alpha amino acid metabolic process GO:1901605 71 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
negative regulation of hormone secretion GO:0046888 46 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
divalent metal ion transport GO:0070838 132 0.014
response to light stimulus GO:0009416 52 0.014
ras protein signal transduction GO:0007265 29 0.014
response to increased oxygen levels GO:0036296 45 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
organelle organization GO:0006996 266 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
cellular response to peptide GO:1901653 133 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
regulation of metal ion transport GO:0010959 118 0.013
vasculogenesis GO:0001570 3 0.013
negative regulation of ion transport GO:0043271 51 0.013
sensory perception GO:0007600 101 0.013
Rat
cell cycle GO:0007049 101 0.013
cation homeostasis GO:0055080 195 0.013
response to amino acid GO:0043200 75 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
lipid transport GO:0006869 61 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
carboxylic acid catabolic process GO:0046395 49 0.013
cation transmembrane transport GO:0098655 263 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.013
regulation of mapk cascade GO:0043408 116 0.013
regulation of transferase activity GO:0051338 123 0.013
vascular process in circulatory system GO:0003018 96 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
metal ion homeostasis GO:0055065 186 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
regulation of transmembrane transport GO:0034762 122 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
regulation of blood circulation GO:1903522 110 0.013
response to hyperoxia GO:0055093 45 0.013
axon development GO:0061564 96 0.013
Fly
chemosensory behavior GO:0007635 2 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
sodium ion transport GO:0006814 82 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
cytoplasmic transport GO:0016482 115 0.013
response to estradiol GO:0032355 164 0.013
developmental growth involved in morphogenesis GO:0060560 33 0.012
Fly
single organism cellular localization GO:1902580 102 0.012
protein targeting GO:0006605 61 0.012
response to camp GO:0051591 91 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
organophosphate catabolic process GO:0046434 148 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
organic acid catabolic process GO:0016054 49 0.012
glial cell differentiation GO:0010001 65 0.012
neuron death GO:0070997 127 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
cardiac chamber development GO:0003205 1 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
regulation of anatomical structure size GO:0090066 135 0.012
potassium ion transport GO:0006813 97 0.012
response to reactive oxygen species GO:0000302 120 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
cellular cation homeostasis GO:0030003 180 0.012
regulation of camp biosynthetic process GO:0030817 38 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
protein processing GO:0016485 68 0.012
embryonic skeletal system development GO:0048706 3 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
positive regulation of protein modification process GO:0031401 142 0.012
epithelium development GO:0060429 96 0.012
response to activity GO:0014823 73 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
dephosphorylation GO:0016311 98 0.012
muscle cell proliferation GO:0033002 84 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
cellular response to alcohol GO:0097306 87 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
mapk cascade GO:0000165 140 0.011
cell cycle checkpoint GO:0000075 2 0.011
dendrite development GO:0016358 72 0.011
organ morphogenesis GO:0009887 75 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.011
eye morphogenesis GO:0048592 4 0.011
regulation of camp metabolic process GO:0030814 43 0.011
skeletal muscle organ development GO:0060538 33 0.011
negative regulation of cell development GO:0010721 82 0.011
negative regulation of heart growth GO:0061117 3 0.011
regulation of body fluid levels GO:0050878 90 0.011
response to temperature stimulus GO:0009266 94 0.011
Fly
regulation of membrane potential GO:0042391 110 0.011
tonic smooth muscle contraction GO:0014820 4 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
Fly
bmp signaling pathway GO:0030509 4 0.011
fatty acid metabolic process GO:0006631 99 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
adenohypophysis development GO:0021984 2 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
smooth muscle contraction GO:0006939 37 0.011
regulation of embryonic development GO:0045995 2 0.011
camp biosynthetic process GO:0006171 47 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
positive regulation of cell motility GO:2000147 97 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
alcohol metabolic process GO:0006066 77 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
renal system development GO:0072001 67 0.011
phospholipid metabolic process GO:0006644 61 0.011
male gonad development GO:0008584 59 0.011
regulation of cell cycle GO:0051726 73 0.011
calcium ion transport GO:0006816 131 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.011
regulation of tube size GO:0035150 89 0.011
eye development GO:0001654 50 0.011
olfactory behavior GO:0042048 2 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
regulation of kinase activity GO:0043549 117 0.010
circadian rhythm GO:0007623 88 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of locomotion GO:0040017 102 0.010
regulation of neuron projection development GO:0010975 161 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
artery smooth muscle contraction GO:0014824 4 0.010
fertilization GO:0009566 3 0.010
tongue morphogenesis GO:0043587 3 0.010

Pde4c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.056
disease of anatomical entity DOID:7 0 0.056
gastrointestinal system disease DOID:77 0 0.034
sensory system disease DOID:0050155 0 0.031
eye and adnexa disease DOID:1492 0 0.027
cardiovascular system disease DOID:1287 0 0.018
urinary system disease DOID:18 0 0.018
eye disease DOID:5614 0 0.017
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.015
myopathy DOID:423 0 0.015
disease of metabolism DOID:0014667 0 0.014
central nervous system disease DOID:331 0 0.014
brain disease DOID:936 0 0.013
inherited metabolic disorder DOID:655 0 0.011
retinal disease DOID:5679 0 0.010