Rattus norvegicus

12 known processes

Pde4dip

phosphodiesterase 4D interacting protein

Pde4dip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.149
oxoacid metabolic process GO:0043436 290 0.128
ribonucleotide metabolic process GO:0009259 231 0.118
generation of precursor metabolites and energy GO:0006091 62 0.094
carboxylic acid metabolic process GO:0019752 289 0.083
organic acid metabolic process GO:0006082 292 0.083
organophosphate metabolic process GO:0019637 370 0.080
carbohydrate derivative metabolic process GO:1901135 346 0.078
nucleoside phosphate metabolic process GO:0006753 283 0.077
organic substance catabolic process GO:1901575 316 0.074
nucleotide metabolic process GO:0009117 279 0.073
purine nucleotide metabolic process GO:0006163 229 0.073
nucleobase containing small molecule metabolic process GO:0055086 316 0.072
purine containing compound metabolic process GO:0072521 253 0.069
negative regulation of cell death GO:0060548 229 0.066
purine ribonucleotide metabolic process GO:0009150 227 0.061
nucleic acid templated transcription GO:0097659 379 0.060
nucleoside metabolic process GO:0009116 179 0.059
ribonucleoside catabolic process GO:0042454 126 0.056
regulation of molecular function GO:0065009 398 0.056
single organism biosynthetic process GO:0044711 342 0.054
rna biosynthetic process GO:0032774 380 0.054
catabolic process GO:0009056 351 0.053
ribonucleoside metabolic process GO:0009119 174 0.049
regulation of phosphorus metabolic process GO:0051174 349 0.049
ribose phosphate metabolic process GO:0019693 235 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
regulation of protein modification process GO:0031399 194 0.046
organelle organization GO:0006996 266 0.046
nucleoside triphosphate metabolic process GO:0009141 144 0.046
anatomical structure morphogenesis GO:0009653 298 0.045
rna metabolic process GO:0016070 406 0.045
purine nucleoside metabolic process GO:0042278 169 0.045
oxidation reduction process GO:0055114 304 0.045
purine ribonucleoside metabolic process GO:0046128 168 0.044
cellular component assembly GO:0022607 360 0.044
nucleoside monophosphate metabolic process GO:0009123 93 0.043
ribonucleoside triphosphate metabolic process GO:0009199 141 0.041
glycosyl compound metabolic process GO:1901657 182 0.041
lipid metabolic process GO:0006629 283 0.041
protein transport GO:0015031 132 0.041
regulation of nucleotide metabolic process GO:0006140 117 0.041
regulation of programmed cell death GO:0043067 341 0.041
nucleotide catabolic process GO:0009166 139 0.040
programmed cell death GO:0012501 392 0.040
regulation of protein metabolic process GO:0051246 289 0.039
regulation of rna biosynthetic process GO:2001141 381 0.039
response to estrogen GO:0043627 232 0.039
transcription dna templated GO:0006351 377 0.039
cellular component biogenesis GO:0044085 368 0.038
energy derivation by oxidation of organic compounds GO:0015980 46 0.038
cellular response to hormone stimulus GO:0032870 247 0.037
regulation of apoptotic process GO:0042981 335 0.037
macromolecular complex assembly GO:0065003 273 0.037
purine ribonucleoside catabolic process GO:0046130 124 0.036
aromatic compound catabolic process GO:0019439 168 0.036
protein targeting GO:0006605 61 0.034
protein localization to organelle GO:0033365 57 0.034
single organism catabolic process GO:0044712 283 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
cellular response to nitrogen compound GO:1901699 210 0.033
cellular response to peptide GO:1901653 133 0.033
nucleoside phosphate catabolic process GO:1901292 140 0.032
protein complex subunit organization GO:0071822 302 0.032
negative regulation of programmed cell death GO:0043069 183 0.032
organonitrogen compound catabolic process GO:1901565 179 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
regulation of cellular component organization GO:0051128 368 0.031
negative regulation of transport GO:0051051 136 0.031
neuron differentiation GO:0030182 368 0.030
response to inorganic substance GO:0010035 377 0.030
intracellular protein transport GO:0006886 79 0.030
negative regulation of apoptotic process GO:0043066 181 0.029
regulation of signal transduction GO:0009966 318 0.029
nucleoside catabolic process GO:0009164 126 0.029
regulation of catalytic activity GO:0050790 304 0.028
single organism cellular localization GO:1902580 102 0.028
response to oxidative stress GO:0006979 186 0.028
muscle system process GO:0003012 115 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.028
protein phosphorylation GO:0006468 345 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
protein complex assembly GO:0006461 263 0.027
intracellular signal transduction GO:0035556 314 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
cellular catabolic process GO:0044248 295 0.027
cellular homeostasis GO:0019725 252 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
response to carbohydrate GO:0009743 183 0.026
purine nucleoside monophosphate metabolic process GO:0009126 84 0.026
protein homooligomerization GO:0051260 91 0.026
apoptotic process GO:0006915 381 0.026
response to peptide GO:1901652 292 0.026
single organism organelle organization GO:1902589 180 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
cell projection organization GO:0030030 302 0.026
regulation of rna metabolic process GO:0051252 391 0.025
cytoplasmic transport GO:0016482 115 0.025
regulation of cellular localization GO:0060341 263 0.025
positive regulation of neuron differentiation GO:0045666 126 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
negative regulation of metabolic process GO:0009892 331 0.025
neuron development GO:0048666 286 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
neuron death GO:0070997 127 0.024
response to peptide hormone GO:0043434 278 0.024
amine metabolic process GO:0009308 38 0.024
glycosyl compound catabolic process GO:1901658 126 0.024
cellular respiration GO:0045333 21 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
regulation of cell differentiation GO:0045595 320 0.023
regulation of transcription dna templated GO:0006355 374 0.023
heterocycle catabolic process GO:0046700 167 0.023
response to hexose GO:0009746 144 0.023
neuron projection morphogenesis GO:0048812 122 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
secretion by cell GO:0032940 248 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.022
purine nucleoside triphosphate catabolic process GO:0009146 122 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.022
macromolecule localization GO:0033036 252 0.022
glycogen metabolic process GO:0005977 23 0.022
regulation of transferase activity GO:0051338 123 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
regulation of cell development GO:0060284 263 0.021
cytoskeleton organization GO:0007010 111 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
regulation of neuron death GO:1901214 115 0.021
regulation of potassium ion transport GO:0043266 29 0.021
synaptic transmission GO:0007268 235 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
purine nucleotide catabolic process GO:0006195 136 0.021
protein oligomerization GO:0051259 191 0.020
protein localization GO:0008104 191 0.020
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
neuron projection development GO:0031175 273 0.020
positive regulation of protein modification process GO:0031401 142 0.020
cellular amine metabolic process GO:0044106 38 0.020
establishment of protein localization GO:0045184 141 0.020
purine containing compound catabolic process GO:0072523 138 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
cellular component movement GO:0006928 248 0.020
intracellular transport GO:0046907 185 0.020
regulation of protein phosphorylation GO:0001932 183 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
response to cytokine GO:0034097 215 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
regulation of nervous system development GO:0051960 264 0.019
cellular chemical homeostasis GO:0055082 247 0.019
blood circulation GO:0008015 183 0.019
ribonucleotide catabolic process GO:0009261 136 0.018
response to reactive oxygen species GO:0000302 120 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
positive regulation of molecular function GO:0044093 230 0.018
response to camp GO:0051591 91 0.018
actin filament based process GO:0030029 86 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
regulation of phosphorylation GO:0042325 248 0.018
regulation of system process GO:0044057 208 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of muscle system process GO:0090257 79 0.018
cell morphogenesis involved in differentiation GO:0000904 119 0.018
pyruvate metabolic process GO:0006090 27 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
organ morphogenesis GO:0009887 75 0.017
single organism intracellular transport GO:1902582 166 0.017
response to extracellular stimulus GO:0009991 380 0.017
positive regulation of cell communication GO:0010647 271 0.017
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
striated muscle contraction GO:0006941 44 0.017
calcium ion homeostasis GO:0055074 162 0.017
cellular ketone metabolic process GO:0042180 51 0.016
nuclear transport GO:0051169 49 0.016
protein import GO:0017038 37 0.016
chemical homeostasis GO:0048878 292 0.016
homeostatic process GO:0042592 331 0.016
regulation of neurogenesis GO:0050767 247 0.016
ribonucleoside monophosphate metabolic process GO:0009161 88 0.016
response to wounding GO:0009611 254 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
response to monosaccharide GO:0034284 159 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regulation of protein kinase activity GO:0045859 105 0.016
anion transport GO:0006820 178 0.016
regulation of kinase activity GO:0043549 117 0.016
regulation of neuron projection development GO:0010975 161 0.016
positive regulation of gene expression GO:0010628 244 0.015
regulation of membrane potential GO:0042391 110 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
regulation of metal ion transport GO:0010959 118 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
cellular macromolecule localization GO:0070727 122 0.015
establishment of protein localization to organelle GO:0072594 44 0.015
positive regulation of cell development GO:0010720 176 0.015
ion homeostasis GO:0050801 212 0.015
response to metal ion GO:0010038 253 0.015
central nervous system development GO:0007417 311 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of transmembrane transport GO:0034762 122 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
regulation of anatomical structure size GO:0090066 135 0.015
regulation of ion transmembrane transporter activity GO:0032412 48 0.015
cellular response to stress GO:0033554 269 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
potassium ion transport GO:0006813 97 0.015
response to external biotic stimulus GO:0043207 221 0.015
macromolecule catabolic process GO:0009057 58 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
regulation of ion transport GO:0043269 245 0.014
response to other organism GO:0051707 220 0.014
circulatory system process GO:0003013 183 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of hydrolase activity GO:0051336 143 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
tricarboxylic acid metabolic process GO:0072350 10 0.014
carbohydrate catabolic process GO:0016052 40 0.014
positive regulation of nucleoside metabolic process GO:0045979 55 0.014
positive regulation of nervous system development GO:0051962 178 0.014
response to growth factor GO:0070848 189 0.014
neurological system process GO:0050877 219 0.014
transmembrane transport GO:0055085 412 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
cellular ion homeostasis GO:0006873 184 0.014
protein dephosphorylation GO:0006470 38 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
single organism nuclear import GO:1902593 35 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
citrate metabolic process GO:0006101 3 0.013
axon development GO:0061564 96 0.013
response to nutrient GO:0007584 248 0.013
regulation of catabolic process GO:0009894 113 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
response to bacterium GO:0009617 200 0.013
cell cell signaling GO:0007267 335 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
defense response GO:0006952 194 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
rna localization GO:0006403 4 0.013
cardiovascular system development GO:0072358 134 0.013
positive regulation of transport GO:0051050 245 0.013
positive regulation of catabolic process GO:0009896 78 0.013
response to glucose GO:0009749 136 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to mechanical stimulus GO:0009612 134 0.013
protein import into nucleus GO:0006606 35 0.013
circulatory system development GO:0072359 134 0.013
organophosphate catabolic process GO:0046434 148 0.013
protein tetramerization GO:0051262 38 0.013
muscle contraction GO:0006936 88 0.013
positive regulation of nucleotide catabolic process GO:0030813 53 0.013
negative regulation of molecular function GO:0044092 133 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
neuron apoptotic process GO:0051402 88 0.013
negative regulation of neuron death GO:1901215 69 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
vesicle mediated transport GO:0016192 181 0.012
response to estradiol GO:0032355 164 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
positive regulation of developmental process GO:0051094 283 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
heart morphogenesis GO:0003007 3 0.012
response to purine containing compound GO:0014074 126 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
regulation of cell projection organization GO:0031344 175 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
regulation of cell proliferation GO:0042127 359 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
regulation of response to stress GO:0080134 126 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
peptidyl amino acid modification GO:0018193 126 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
acetyl coa metabolic process GO:0006084 17 0.011
carbohydrate metabolic process GO:0005975 130 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
positive regulation of signaling GO:0023056 270 0.011
b cell differentiation GO:0030183 2 0.011
response to temperature stimulus GO:0009266 94 0.011
regulation of map kinase activity GO:0043405 53 0.011
ion transmembrane transport GO:0034220 365 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
protein complex biogenesis GO:0070271 263 0.011
multicellular organism growth GO:0035264 1 0.011
metal ion transport GO:0030001 289 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
cellular protein complex assembly GO:0043623 44 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
cell motility GO:0048870 202 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
forebrain development GO:0030900 98 0.011
atp metabolic process GO:0046034 72 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
cation homeostasis GO:0055080 195 0.010
regulation of hormone levels GO:0010817 187 0.010
dephosphorylation GO:0016311 98 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
response to biotic stimulus GO:0009607 226 0.010
organelle localization GO:0051640 55 0.010

Pde4dip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.066
carbohydrate metabolic disorder DOID:2978 0 0.066
inherited metabolic disorder DOID:655 0 0.066
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.014
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011