Rattus norvegicus

17 known processes

Pdk4

pyruvate dehydrogenase kinase, isozyme 4

Pdk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regeneration GO:0031099 163 0.742
response to insulin GO:0032868 133 0.647
Human
organ regeneration GO:0031100 101 0.468
cellular response to endogenous stimulus GO:0071495 377 0.432
Human
oxidation reduction process GO:0055114 304 0.347
monocarboxylic acid metabolic process GO:0032787 152 0.346
Human
macromolecule localization GO:0033036 252 0.325
macromolecular complex subunit organization GO:0043933 339 0.307
protein complex assembly GO:0006461 263 0.291
macromolecular complex assembly GO:0065003 273 0.272
ion transmembrane transport GO:0034220 365 0.270
protein complex subunit organization GO:0071822 302 0.266
response to estrogen GO:0043627 232 0.263
cellular response to peptide hormone stimulus GO:0071375 120 0.212
Human
protein homooligomerization GO:0051260 91 0.204
transmembrane transport GO:0055085 412 0.197
organic substance catabolic process GO:1901575 316 0.194
reproductive process GO:0022414 372 0.185
protein complex biogenesis GO:0070271 263 0.182
regulation of phosphorus metabolic process GO:0051174 349 0.178
Human
response to peptide GO:1901652 292 0.178
Human
circulatory system development GO:0072359 134 0.176
protein oligomerization GO:0051259 191 0.172
response to external biotic stimulus GO:0043207 221 0.163
cardiovascular system development GO:0072358 134 0.163
nucleic acid templated transcription GO:0097659 379 0.154
anatomical structure morphogenesis GO:0009653 298 0.154
response to hexose GO:0009746 144 0.151
cellular component assembly GO:0022607 360 0.144
cellular component biogenesis GO:0044085 368 0.140
regulation of cellular protein metabolic process GO:0032268 267 0.134
response to growth factor GO:0070848 189 0.134
regulation of programmed cell death GO:0043067 341 0.120
Human
response to temperature stimulus GO:0009266 94 0.119
neuron development GO:0048666 286 0.115
secretion GO:0046903 307 0.114
regulation of transforming growth factor beta3 production GO:0032910 2 0.114
fatty acid oxidation GO:0019395 29 0.112
response to hypoxia GO:0001666 231 0.105
cellular response to oxygen containing compound GO:1901701 386 0.105
Human
regulation of molecular function GO:0065009 398 0.104
fatty acid metabolic process GO:0006631 99 0.103
Human
response to biotic stimulus GO:0009607 226 0.103
cellular response to hormone stimulus GO:0032870 247 0.103
Human
protein transport GO:0015031 132 0.102
cellular protein localization GO:0034613 122 0.102
response to other organism GO:0051707 220 0.097
positive regulation of locomotion GO:0040017 102 0.096
choline transport GO:0015871 4 0.095
cellular response to peptide GO:1901653 133 0.094
Human
response to ketone GO:1901654 182 0.093
epithelium development GO:0060429 96 0.091
positive regulation of signaling GO:0023056 270 0.091
cellular carbohydrate metabolic process GO:0044262 72 0.088
Human
single organism reproductive process GO:0044702 297 0.087
lipid oxidation GO:0034440 30 0.086
carboxylic acid metabolic process GO:0019752 289 0.085
Human
regulation of rna metabolic process GO:0051252 391 0.084
homeostatic process GO:0042592 331 0.083
gland development GO:0048732 155 0.083
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.082
regulation of cellular localization GO:0060341 263 0.082
transcription dna templated GO:0006351 377 0.082
response to organophosphorus GO:0046683 102 0.081
regulation of telomerase activity GO:0051972 2 0.080
positive regulation of developmental process GO:0051094 283 0.079
cellular lipid metabolic process GO:0044255 208 0.078
Human
negative regulation of nucleic acid templated transcription GO:1903507 117 0.076
apoptotic process GO:0006915 381 0.075
Human
response to wounding GO:0009611 254 0.073
regulation of phagocytosis engulfment GO:0060099 4 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.069
catabolic process GO:0009056 351 0.069
multi organism reproductive process GO:0044703 262 0.068
cellular response to organonitrogen compound GO:0071417 197 0.067
Human
neuron differentiation GO:0030182 368 0.066
establishment of protein localization GO:0045184 141 0.066
divalent metal ion transport GO:0070838 132 0.066
positive regulation of cell motility GO:2000147 97 0.066
cellular component morphogenesis GO:0032989 155 0.066
response to glucocorticoid GO:0051384 223 0.065
positive regulation of signal transduction GO:0009967 175 0.065
negative regulation of cellular metabolic process GO:0031324 281 0.065
oxoacid metabolic process GO:0043436 290 0.064
Human
response to carbohydrate GO:0009743 183 0.064
single organism catabolic process GO:0044712 283 0.063
fatty acid catabolic process GO:0009062 26 0.063
regulation of phosphate metabolic process GO:0019220 349 0.063
response to corticosteroid GO:0031960 235 0.063
response to metformin GO:1901558 1 0.063
cellular response to corticosteroid stimulus GO:0071384 69 0.063
positive regulation of catalytic activity GO:0043085 184 0.060
regulation of catalytic activity GO:0050790 304 0.060
regulation of locomotion GO:0040012 148 0.060
vitamin d receptor signaling pathway GO:0070561 1 0.059
signal release GO:0023061 145 0.059
protein localization GO:0008104 191 0.059
positive regulation of cell communication GO:0010647 271 0.058
programmed cell death GO:0012501 392 0.058
Human
cellular response to growth factor stimulus GO:0071363 162 0.058
regulation of transcription dna templated GO:0006355 374 0.058
response to glucose GO:0009749 136 0.057
cellular catabolic process GO:0044248 295 0.057
cell morphogenesis involved in differentiation GO:0000904 119 0.056
endothelium development GO:0003158 12 0.056
reproduction GO:0000003 245 0.055
chemical homeostasis GO:0048878 292 0.055
nitrogen compound transport GO:0071705 229 0.055
positive regulation of response to stimulus GO:0048584 285 0.055
aging GO:0007568 241 0.054
response to purine containing compound GO:0014074 126 0.054
cellular response to insulin stimulus GO:0032869 81 0.054
Human
rna biosynthetic process GO:0032774 380 0.053
negative regulation of transport GO:0051051 136 0.053
nucleoside phosphate metabolic process GO:0006753 283 0.052
organophosphate metabolic process GO:0019637 370 0.051
positive regulation of cell development GO:0010720 176 0.051
regulation of cellular component movement GO:0051270 150 0.050
positive regulation of cell proliferation GO:0008284 249 0.049
response to metal ion GO:0010038 253 0.048
negative regulation of metabolic process GO:0009892 331 0.048
regulation of peptide hormone secretion GO:0090276 80 0.048
tissue development GO:0009888 252 0.048
positive regulation of cellular biosynthetic process GO:0031328 295 0.048
reproductive system development GO:0061458 128 0.048
lipid catabolic process GO:0016042 46 0.047
g protein coupled receptor signaling pathway GO:0007186 242 0.047
response to oxygen levels GO:0070482 265 0.046
regulation of protein metabolic process GO:0051246 289 0.046
response to lipopolysaccharide GO:0032496 191 0.046
dna metabolic process GO:0006259 96 0.046
positive regulation of multicellular organismal process GO:0051240 387 0.046
carbohydrate metabolic process GO:0005975 130 0.045
Human
regulation of cell proliferation GO:0042127 359 0.045
regulation of signal transduction GO:0009966 318 0.045
organic cyclic compound catabolic process GO:1901361 175 0.045
regulation of cellular ketone metabolic process GO:0010565 27 0.045
Human
neuron projection morphogenesis GO:0048812 122 0.044
insulin secretion GO:0030073 69 0.044
response to reactive oxygen species GO:0000302 120 0.044
transcription from rna polymerase ii promoter GO:0006366 252 0.043
response to peptide hormone GO:0043434 278 0.043
Human
positive regulation of cell differentiation GO:0045597 217 0.043
negative regulation of multicellular organismal process GO:0051241 203 0.043
regulation of response to external stimulus GO:0032101 106 0.043
immune system process GO:0002376 204 0.043
response to monosaccharide GO:0034284 159 0.043
cellular chemical homeostasis GO:0055082 247 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.042
response to acid chemical GO:0001101 222 0.042
Human
positive regulation of gene expression GO:0010628 244 0.041
endothelial cell differentiation GO:0045446 9 0.041
regulation of endothelial cell apoptotic process GO:2000351 3 0.041
sensory perception GO:0007600 101 0.041
regulation of protein phosphorylation GO:0001932 183 0.041
epithelial cell differentiation GO:0030855 71 0.040
negative regulation of transcription dna templated GO:0045892 116 0.040
hormone secretion GO:0046879 115 0.040
alcohol metabolic process GO:0006066 77 0.040
positive regulation of rna metabolic process GO:0051254 203 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
regulation of cell migration GO:0030334 128 0.039
vitamin a metabolic process GO:0006776 2 0.039
regulation of secretion by cell GO:1903530 208 0.039
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.039
secretion by cell GO:0032940 248 0.039
cytoplasmic transport GO:0016482 115 0.039
response to ethanol GO:0045471 162 0.038
positive regulation of phagocytosis engulfment GO:0060100 4 0.037
regulation of apoptotic process GO:0042981 335 0.037
Human
regulation of response to stress GO:0080134 126 0.037
regulation of protein modification process GO:0031399 194 0.037
lipid localization GO:0010876 62 0.037
protein localization to organelle GO:0033365 57 0.036
response to oxidative stress GO:0006979 186 0.036
central nervous system development GO:0007417 311 0.036
purine ribonucleotide metabolic process GO:0009150 227 0.036
lipid metabolic process GO:0006629 283 0.036
Human
immune response GO:0006955 104 0.035
positive regulation of phosphate metabolic process GO:0045937 262 0.035
regulation of cell development GO:0060284 263 0.035
positive regulation of cellular component movement GO:0051272 102 0.035
negative regulation of apoptotic process GO:0043066 181 0.035
Human
response to molecule of fungal origin GO:0002238 3 0.035
single organism behavior GO:0044708 130 0.034
inflammatory response GO:0006954 150 0.034
positive regulation of neuron differentiation GO:0045666 126 0.034
growth GO:0040007 165 0.034
single organism biosynthetic process GO:0044711 342 0.034
Human
regulation of cellular component organization GO:0051128 368 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
protein phosphorylation GO:0006468 345 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
cellular calcium ion homeostasis GO:0006874 160 0.033
cellular response to cytokine stimulus GO:0071345 127 0.033
hormone transport GO:0009914 121 0.033
positive regulation of protein metabolic process GO:0051247 178 0.032
cell morphogenesis GO:0000902 142 0.032
developmental process involved in reproduction GO:0003006 159 0.032
gliogenesis GO:0042063 93 0.032
regulation of cytokine production GO:0001817 56 0.032
regulation of nervous system development GO:0051960 264 0.032
enzyme linked receptor protein signaling pathway GO:0007167 116 0.032
Human
cell growth GO:0016049 104 0.032
response to cold GO:0009409 29 0.031
negative regulation of gene expression GO:0010629 199 0.031
aromatic compound catabolic process GO:0019439 168 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
positive regulation of isotype switching GO:0045830 1 0.031
response to inorganic substance GO:0010035 377 0.031
positive regulation of focal adhesion assembly GO:0051894 2 0.030
response to decreased oxygen levels GO:0036293 237 0.030
cofactor metabolic process GO:0051186 95 0.030
Human
regulation of cell motility GO:2000145 131 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
single organism intracellular transport GO:1902582 166 0.030
regulation of peptide transport GO:0090087 87 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
multicellular organism growth GO:0035264 1 0.030
regulation of multicellular organismal development GO:2000026 376 0.029
heart development GO:0007507 72 0.029
response to nutrient GO:0007584 248 0.029
ribonucleotide metabolic process GO:0009259 231 0.029
protein heterooligomerization GO:0051291 89 0.029
intracellular transport GO:0046907 185 0.029
antibiotic transport GO:0042891 2 0.028
sodium ion transport GO:0006814 82 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
negative regulation of molecular function GO:0044092 133 0.028
rna metabolic process GO:0016070 406 0.028
response to fatty acid GO:0070542 65 0.028
Human
negative regulation of biosynthetic process GO:0009890 168 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
Human
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.027
cell migration GO:0016477 197 0.027
response to nutrient levels GO:0031667 370 0.027
Human
vesicle mediated transport GO:0016192 181 0.027
positive regulation of nervous system development GO:0051962 178 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
response to progesterone GO:0032570 48 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
regulation of hormone secretion GO:0046883 106 0.026
positive regulation of biomineral tissue development GO:0070169 4 0.026
signal transduction by phosphorylation GO:0023014 144 0.026
single organism nuclear import GO:1902593 35 0.026
negative regulation of rna biosynthetic process GO:1902679 118 0.026
regulation of hydrolase activity GO:0051336 143 0.026
ribonucleoside catabolic process GO:0042454 126 0.026
cellular macromolecule localization GO:0070727 122 0.026
female pregnancy GO:0007565 122 0.026
rhythmic process GO:0048511 156 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
development of primary sexual characteristics GO:0045137 107 0.026
response to radiation GO:0009314 137 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
Human
response to mechanical stimulus GO:0009612 134 0.025
amide transport GO:0042886 105 0.025
multicellular organism reproduction GO:0032504 233 0.025
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.025
cellular response to organic cyclic compound GO:0071407 202 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
glucose homeostasis GO:0042593 75 0.025
organic acid metabolic process GO:0006082 292 0.025
Human
mrna transcription GO:0009299 2 0.025
heart morphogenesis GO:0003007 3 0.025
purine nucleotide catabolic process GO:0006195 136 0.024
regulation of kinase activity GO:0043549 117 0.024
cellular amine metabolic process GO:0044106 38 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
Human
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
lipid transport GO:0006869 61 0.024
nucleoside phosphate catabolic process GO:1901292 140 0.024
neuron projection development GO:0031175 273 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
regulation of neurogenesis GO:0050767 247 0.023
purine containing compound metabolic process GO:0072521 253 0.023
amine metabolic process GO:0009308 38 0.023
wound healing GO:0042060 122 0.023
cell type specific apoptotic process GO:0097285 134 0.023
negative regulation of bone resorption GO:0045779 5 0.022
positive regulation of cell migration GO:0030335 96 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
pancreatic stellate cell proliferation GO:0072343 2 0.022
reproductive structure development GO:0048608 128 0.022
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.022
cellular protein complex assembly GO:0043623 44 0.022
response to cytokine GO:0034097 215 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.021
monocarboxylic acid catabolic process GO:0072329 28 0.021
intracellular signal transduction GO:0035556 314 0.021
muscle system process GO:0003012 115 0.021
glycogen metabolic process GO:0005977 23 0.021
carbohydrate biosynthetic process GO:0016051 42 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
heterocycle catabolic process GO:0046700 167 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
organ morphogenesis GO:0009887 75 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
negative regulation of developmental process GO:0051093 125 0.021
regulation of immune response GO:0050776 55 0.021
regulation of cell differentiation GO:0045595 320 0.020
nucleotide metabolic process GO:0009117 279 0.020
glucan metabolic process GO:0044042 23 0.020
gamete generation GO:0007276 124 0.020
nuclear transport GO:0051169 49 0.020
regulation of blood circulation GO:1903522 110 0.020
dephosphorylation GO:0016311 98 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
single organism organelle organization GO:1902589 180 0.020
peptide transport GO:0015833 97 0.020
peptide secretion GO:0002790 86 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
cellular response to stress GO:0033554 269 0.020
Human
regulation of catabolic process GO:0009894 113 0.020
regulation of protein kinase activity GO:0045859 105 0.020
regulation of cellular catabolic process GO:0031329 101 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cellular response to glucocorticoid stimulus GO:0071385 68 0.019
hepaticobiliary system development GO:0061008 90 0.019
response to interleukin 1 GO:0070555 55 0.019
membrane organization GO:0061024 94 0.019
response to extracellular stimulus GO:0009991 380 0.019
Human
liver development GO:0001889 90 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
bmp signaling pathway GO:0030509 4 0.019
cellular lipid catabolic process GO:0044242 37 0.019
positive regulation of cell death GO:0010942 184 0.019
respiratory gaseous exchange GO:0007585 4 0.019
negative regulation of cell death GO:0060548 229 0.019
Human
carbohydrate homeostasis GO:0033500 75 0.019
cellular response to lipid GO:0071396 201 0.019
Human
cell cell signaling GO:0007267 335 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
regulation of insulin secretion GO:0050796 65 0.018
regulation of phosphorylation GO:0042325 248 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
positive regulation of immune system process GO:0002684 90 0.018
organophosphate catabolic process GO:0046434 148 0.018
response to toxic substance GO:0009636 133 0.018
regulation of immune system process GO:0002682 123 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.018
cytokine mediated signaling pathway GO:0019221 43 0.018
learning or memory GO:0007611 90 0.018
tissue regeneration GO:0042246 36 0.018
sequestering of triglyceride GO:0030730 1 0.018
smooth muscle cell migration GO:0014909 36 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
regulation of hormone levels GO:0010817 187 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
regulation of transferase activity GO:0051338 123 0.018
negative regulation of blood pressure GO:0045776 29 0.017
glutathione transport GO:0034635 2 0.017
head development GO:0060322 247 0.017
cellular homeostasis GO:0019725 252 0.017
response to cocaine GO:0042220 39 0.017
regulation of map kinase activity GO:0043405 53 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
regulation of vasculature development GO:1901342 44 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
cation transmembrane transport GO:0098655 263 0.017
positive regulation of protein modification process GO:0031401 142 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
regulation of body fluid levels GO:0050878 90 0.017
response to epidermal growth factor GO:0070849 18 0.017
cellular component movement GO:0006928 248 0.017
response to bacterium GO:0009617 200 0.017
development of primary female sexual characteristics GO:0046545 56 0.017
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 3 0.017
organelle organization GO:0006996 266 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
negative regulation of secretion by cell GO:1903531 72 0.016
regulation of neuron differentiation GO:0045664 208 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
smad protein complex assembly GO:0007183 1 0.016
gastrulation GO:0007369 2 0.016
fertilization GO:0009566 3 0.016
defense response to gram positive bacterium GO:0050830 2 0.016
peptide hormone secretion GO:0030072 84 0.016
cognition GO:0050890 92 0.016
mesoderm development GO:0007498 2 0.016
blood vessel development GO:0001568 69 0.016
metal ion transport GO:0030001 289 0.016
response to ionizing radiation GO:0010212 59 0.016
cell projection morphogenesis GO:0048858 123 0.016
coenzyme metabolic process GO:0006732 86 0.016
Human
establishment of protein localization to organelle GO:0072594 44 0.016
cellular macromolecular complex assembly GO:0034622 58 0.016
glial cell differentiation GO:0010001 65 0.016
small molecule catabolic process GO:0044282 59 0.016
cellular cation homeostasis GO:0030003 180 0.016
polysaccharide metabolic process GO:0005976 25 0.016
leukocyte activation GO:0045321 76 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
positive regulation of molecular function GO:0044093 230 0.016
response to dexamethasone GO:0071548 49 0.015
negative regulation of secretion GO:0051048 82 0.015
regulation of system process GO:0044057 208 0.015
cellular response to monosaccharide stimulus GO:0071326 67 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.015
cation transport GO:0006812 382 0.015
amino acid betaine transport GO:0015838 1 0.015
positive regulation of adherens junction organization GO:1903393 2 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
lipid storage GO:0019915 1 0.015
metal ion homeostasis GO:0055065 186 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
positive regulation of map kinase activity GO:0043406 46 0.015
regulation of response to wounding GO:1903034 69 0.015
carboxylic acid catabolic process GO:0046395 49 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.014
regulation of protein processing GO:0070613 50 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
organ formation GO:0048645 3 0.014
sexual reproduction GO:0019953 148 0.014
toxin transport GO:1901998 3 0.014
regulation of secretion GO:0051046 224 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
gonad development GO:0008406 104 0.014
negative regulation of homeostatic process GO:0032845 47 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
glycerol 3 phosphate metabolic process GO:0006072 2 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
hemostasis GO:0007599 26 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.014
placenta development GO:0001890 22 0.014
serotonin receptor signaling pathway GO:0007210 10 0.014
coronary vasculature morphogenesis GO:0060977 3 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
urinary bladder smooth muscle contraction GO:0014832 4 0.014
tube development GO:0035295 89 0.014
cellular response to hexose stimulus GO:0071331 65 0.014
ras protein signal transduction GO:0007265 29 0.014
response to vitamin GO:0033273 131 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
negative regulation of multicellular organismal metabolic process GO:0044252 4 0.014
kidney development GO:0001822 67 0.014
anion transmembrane transport GO:0098656 77 0.013
regulation of cell projection organization GO:0031344 175 0.013
innate immune response GO:0045087 35 0.013
spermatogenesis GO:0007283 99 0.013
protein import GO:0017038 37 0.013
regulation of defense response GO:0031347 68 0.013
nucleoside metabolic process GO:0009116 179 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
response to calcium ion GO:0051592 59 0.013
catecholamine transport GO:0051937 37 0.013
endothelial cell morphogenesis GO:0001886 1 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
regulation of growth GO:0040008 105 0.013
ion homeostasis GO:0050801 212 0.013
positive regulation of protein tyrosine kinase activity GO:0061098 2 0.013
biological adhesion GO:0022610 110 0.013
negative regulation of response to wounding GO:1903035 23 0.013
regulation of homeostatic process GO:0032844 101 0.013
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.013
immune system development GO:0002520 41 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
energy derivation by oxidation of organic compounds GO:0015980 46 0.013
positive regulation of insulin secretion GO:0032024 36 0.013
negative regulation of collagen biosynthetic process GO:0032966 4 0.013
purine containing compound catabolic process GO:0072523 138 0.013
negative regulation of signaling GO:0023057 157 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
regulation of sodium ion transport GO:0002028 21 0.013
regulation of neuron projection development GO:0010975 161 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013

Pdk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
musculoskeletal system disease DOID:17 0 0.073
nutrition disease DOID:374 0 0.068
acquired metabolic disease DOID:0060158 0 0.068
disease of metabolism DOID:0014667 0 0.068
obesity DOID:9970 0 0.068
overnutrition DOID:654 0 0.068
muscle tissue disease DOID:66 0 0.031
muscular disease DOID:0080000 0 0.031
myopathy DOID:423 0 0.031
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.018
connective tissue disease DOID:65 0 0.016
cardiovascular system disease DOID:1287 0 0.014