Rattus norvegicus

11 known processes

Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

(Aliases: AS3,FLJ23236,Aprin,KIAA0979,CG008)

Pds5b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.351
transcription dna templated GO:0006351 377 0.336
rna metabolic process GO:0016070 406 0.242
rna biosynthetic process GO:0032774 380 0.214
negative regulation of cellular biosynthetic process GO:0031327 161 0.196
negative regulation of macromolecule metabolic process GO:0010605 260 0.153
nucleic acid templated transcription GO:0097659 379 0.148
negative regulation of transcription dna templated GO:0045892 116 0.143
negative regulation of metabolic process GO:0009892 331 0.138
regulation of protein metabolic process GO:0051246 289 0.138
negative regulation of gene expression GO:0010629 199 0.126
regulation of nucleic acid templated transcription GO:1903506 380 0.126
negative regulation of cellular metabolic process GO:0031324 281 0.122
organic acid metabolic process GO:0006082 292 0.115
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.105
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.105
regulation of transcription dna templated GO:0006355 374 0.100
cellular component assembly GO:0022607 360 0.097
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.092
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.088
regulation of rna biosynthetic process GO:2001141 381 0.087
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.087
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.087
intracellular signal transduction GO:0035556 314 0.081
regulation of apoptotic process GO:0042981 335 0.080
negative regulation of rna biosynthetic process GO:1902679 118 0.077
regulation of molecular function GO:0065009 398 0.075
regulation of rna metabolic process GO:0051252 391 0.074
protein phosphorylation GO:0006468 345 0.071
negative regulation of biosynthetic process GO:0009890 168 0.070
apoptotic process GO:0006915 381 0.062
positive regulation of neurogenesis GO:0050769 165 0.061
negative regulation of rna metabolic process GO:0051253 123 0.059
carboxylic acid metabolic process GO:0019752 289 0.058
negative regulation of nucleic acid templated transcription GO:1903507 117 0.057
neuron differentiation GO:0030182 368 0.055
negative regulation of cell death GO:0060548 229 0.055
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.054
single organism reproductive process GO:0044702 297 0.052
cellular amine metabolic process GO:0044106 38 0.049
behavior GO:0007610 205 0.049
chromosome segregation GO:0007059 2 0.048
regulation of signal transduction GO:0009966 318 0.047
positive regulation of cell communication GO:0010647 271 0.047
regulation of cellular component organization GO:0051128 368 0.046
cellular protein localization GO:0034613 122 0.045
amine metabolic process GO:0009308 38 0.045
regulation of cellular localization GO:0060341 263 0.044
multi organism reproductive process GO:0044703 262 0.044
developmental process involved in reproduction GO:0003006 159 0.043
cell projection organization GO:0030030 302 0.042
purine nucleotide metabolic process GO:0006163 229 0.042
purine ribonucleotide metabolic process GO:0009150 227 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
positive regulation of response to stimulus GO:0048584 285 0.040
regulation of nervous system development GO:0051960 264 0.040
cellular ketone metabolic process GO:0042180 51 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
multicellular organism reproduction GO:0032504 233 0.039
cellular amino acid metabolic process GO:0006520 107 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.038
macromolecular complex assembly GO:0065003 273 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.038
cellular component biogenesis GO:0044085 368 0.038
reproductive process GO:0022414 372 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
nucleotide metabolic process GO:0009117 279 0.036
neuron death GO:0070997 127 0.036
positive regulation of gene expression GO:0010628 244 0.036
positive regulation of transcription dna templated GO:0045893 197 0.036
regulation of secretion GO:0051046 224 0.035
regulation of neuron death GO:1901214 115 0.035
cellular response to growth factor stimulus GO:0071363 162 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
regulation of protein phosphorylation GO:0001932 183 0.035
programmed cell death GO:0012501 392 0.034
regulation of neuron differentiation GO:0045664 208 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
nucleoside triphosphate metabolic process GO:0009141 144 0.033
regulation of protein modification process GO:0031399 194 0.033
organophosphate metabolic process GO:0019637 370 0.033
cation transport GO:0006812 382 0.033
regulation of cell differentiation GO:0045595 320 0.033
reproduction GO:0000003 245 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
ribonucleotide metabolic process GO:0009259 231 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
cell cell signaling GO:0007267 335 0.033
purine containing compound metabolic process GO:0072521 253 0.032
response to radiation GO:0009314 137 0.032
regulation of neuron apoptotic process GO:0043523 83 0.032
response to decreased oxygen levels GO:0036293 237 0.032
central nervous system development GO:0007417 311 0.032
anatomical structure morphogenesis GO:0009653 298 0.031
response to oxygen levels GO:0070482 265 0.031
oxoacid metabolic process GO:0043436 290 0.031
cellular catabolic process GO:0044248 295 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
response to extracellular stimulus GO:0009991 380 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
regulation of organelle organization GO:0033043 80 0.030
neuron development GO:0048666 286 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
organelle localization GO:0051640 55 0.029
negative regulation of signaling GO:0023057 157 0.029
mitotic spindle organization GO:0007052 2 0.029
positive regulation of transport GO:0051050 245 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
regulation of cell projection organization GO:0031344 175 0.029
response to nutrient levels GO:0031667 370 0.029
response to inorganic substance GO:0010035 377 0.028
positive regulation of catalytic activity GO:0043085 184 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
response to growth factor GO:0070848 189 0.028
regulation of catabolic process GO:0009894 113 0.027
positive regulation of cell projection organization GO:0031346 111 0.027
regulation of programmed cell death GO:0043067 341 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
single organism cellular localization GO:1902580 102 0.027
catabolic process GO:0009056 351 0.026
neurological system process GO:0050877 219 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
cell cycle GO:0007049 101 0.026
cell projection morphogenesis GO:0048858 123 0.026
negative regulation of cellular protein metabolic process GO:0032269 106 0.025
male mating behavior GO:0060179 3 0.025
regulation of protein kinase activity GO:0045859 105 0.025
head development GO:0060322 247 0.025
regulation of neuron projection development GO:0010975 161 0.025
neuron apoptotic process GO:0051402 88 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
protein complex assembly GO:0006461 263 0.024
gamete generation GO:0007276 124 0.024
regulation of secretion by cell GO:1903530 208 0.024
positive regulation of molecular function GO:0044093 230 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
secretion GO:0046903 307 0.023
spindle organization GO:0007051 2 0.023
cellular component morphogenesis GO:0032989 155 0.023
cell morphogenesis GO:0000902 142 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
regulation of growth GO:0040008 105 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
negative regulation of cell communication GO:0010648 158 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
regulation of cell proliferation GO:0042127 359 0.022
neuron projection development GO:0031175 273 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
cellular response to stress GO:0033554 269 0.022
regulation of cell development GO:0060284 263 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
biological adhesion GO:0022610 110 0.021
organic substance catabolic process GO:1901575 316 0.021
organophosphate catabolic process GO:0046434 148 0.021
positive regulation of signaling GO:0023056 270 0.021
microtubule organizing center organization GO:0031023 1 0.021
locomotion GO:0040011 237 0.021
response to peptide GO:1901652 292 0.021
regulation of cellular component biogenesis GO:0044087 86 0.021
response to acid chemical GO:0001101 222 0.021
cellular chemical homeostasis GO:0055082 247 0.021
positive regulation of neuron differentiation GO:0045666 126 0.020
regulation of catalytic activity GO:0050790 304 0.020
cell type specific apoptotic process GO:0097285 134 0.020
negative regulation of neuron apoptotic process GO:0043524 45 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
regulation of cell cycle GO:0051726 73 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
regulation of ion transport GO:0043269 245 0.020
positive regulation of nervous system development GO:0051962 178 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
centrosome cycle GO:0007098 1 0.020
protein homooligomerization GO:0051260 91 0.019
response to hypoxia GO:0001666 231 0.019
axis specification GO:0009798 4 0.019
growth GO:0040007 165 0.019
sexual reproduction GO:0019953 148 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
rhythmic process GO:0048511 156 0.019
positive regulation of secretion GO:0051047 140 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
cellular component movement GO:0006928 248 0.019
vesicle mediated transport GO:0016192 181 0.019
metal ion transport GO:0030001 289 0.019
single organism organelle organization GO:1902589 180 0.019
response to ketone GO:1901654 182 0.018
chemical homeostasis GO:0048878 292 0.018
ras protein signal transduction GO:0007265 29 0.018
ion homeostasis GO:0050801 212 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
ovulation cycle GO:0042698 67 0.018
establishment of protein localization GO:0045184 141 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
cellular ion homeostasis GO:0006873 184 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
positive regulation of transcription factor import into nucleus GO:0042993 4 0.018
positive regulation of developmental process GO:0051094 283 0.018
cardiovascular system development GO:0072358 134 0.018
protein localization GO:0008104 191 0.018
cell part morphogenesis GO:0032990 123 0.017
peptidyl amino acid modification GO:0018193 126 0.017
centrosome organization GO:0051297 1 0.017
tissue development GO:0009888 252 0.017
positive regulation of cell death GO:0010942 184 0.017
nucleoside metabolic process GO:0009116 179 0.017
positive regulation of growth GO:0045927 55 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
negative regulation of cell cycle phase transition GO:1901988 4 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of kinase activity GO:0043549 117 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
secretion by cell GO:0032940 248 0.016
cellular homeostasis GO:0019725 252 0.016
regulation of phosphorylation GO:0042325 248 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
aromatic compound catabolic process GO:0019439 168 0.016
regulation of hormone levels GO:0010817 187 0.016
cell cycle checkpoint GO:0000075 2 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
biological phase GO:0044848 17 0.016
hormone transport GO:0009914 121 0.016
tube development GO:0035295 89 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
protein oligomerization GO:0051259 191 0.016
muscle structure development GO:0061061 87 0.016
response to peptide hormone GO:0043434 278 0.016
nucleotide catabolic process GO:0009166 139 0.015
regulation of neurogenesis GO:0050767 247 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.015
regulation of membrane potential GO:0042391 110 0.015
calcium ion transport GO:0006816 131 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
cytoplasmic transport GO:0016482 115 0.015
positive regulation of cell development GO:0010720 176 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
response to estrogen GO:0043627 232 0.015
protein complex subunit organization GO:0071822 302 0.015
regulation of cell growth GO:0001558 85 0.015
cation homeostasis GO:0055080 195 0.015
developmental maturation GO:0021700 25 0.015
sister chromatid segregation GO:0000819 1 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
response to ethanol GO:0045471 162 0.015
regulation of nucleocytoplasmic transport GO:0046822 28 0.015
regulation of immune system process GO:0002682 123 0.015
circulatory system development GO:0072359 134 0.015
gland development GO:0048732 155 0.015
negative regulation of neuron death GO:1901215 69 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
aging GO:0007568 241 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
response to glucocorticoid GO:0051384 223 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
single organism biosynthetic process GO:0044711 342 0.014
epithelial cell proliferation GO:0050673 54 0.014
homeostatic process GO:0042592 331 0.014
regulation of hydrolase activity GO:0051336 143 0.014
response to metal ion GO:0010038 253 0.014
protein transport GO:0015031 132 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
dna metabolic process GO:0006259 96 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of potassium ion transport GO:0043268 13 0.014
response to light stimulus GO:0009416 52 0.014
intracellular transport GO:0046907 185 0.014
protein complex biogenesis GO:0070271 263 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
actin filament based process GO:0030029 86 0.013
synaptic transmission GO:0007268 235 0.013
single organism catabolic process GO:0044712 283 0.013
regulation of protein localization GO:0032880 81 0.013
protein ubiquitination GO:0016567 28 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
purine containing compound catabolic process GO:0072523 138 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
protein modification by small protein conjugation or removal GO:0070647 35 0.013
chromosome organization GO:0051276 36 0.013
mitotic sister chromatid segregation GO:0000070 1 0.013
positive regulation of nucleotide catabolic process GO:0030813 53 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
action potential GO:0001508 54 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
intracellular protein transport GO:0006886 79 0.013
positive regulation of signal transduction GO:0009967 175 0.013
mesoderm development GO:0007498 2 0.012
cell adhesion GO:0007155 110 0.012
positive regulation of catabolic process GO:0009896 78 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
nucleoside catabolic process GO:0009164 126 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
sex differentiation GO:0007548 113 0.012
negative regulation of transport GO:0051051 136 0.012
embryonic skeletal system development GO:0048706 3 0.012
neuronal action potential GO:0019228 35 0.012
lymphocyte homeostasis GO:0002260 2 0.012
protein deubiquitination GO:0016579 4 0.012
regeneration GO:0031099 163 0.012
regulation of muscle system process GO:0090257 79 0.012
single organism behavior GO:0044708 130 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
nuclear transport GO:0051169 49 0.012
single organism nuclear import GO:1902593 35 0.012
muscle system process GO:0003012 115 0.012
cytoskeleton organization GO:0007010 111 0.012
secretion by tissue GO:0032941 37 0.012
cell growth GO:0016049 104 0.012
regulation of hormone secretion GO:0046883 106 0.012
positive regulation of cell growth GO:0030307 44 0.012
negative regulation of protein modification process GO:0031400 52 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
regulation of homeostatic process GO:0032844 101 0.012
carbohydrate metabolic process GO:0005975 130 0.012
cell activation GO:0001775 97 0.011
signal release GO:0023061 145 0.011
divalent metal ion transport GO:0070838 132 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
neuron projection morphogenesis GO:0048812 122 0.011
development of primary sexual characteristics GO:0045137 107 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
positive regulation of protein modification process GO:0031401 142 0.011
macromolecule localization GO:0033036 252 0.011
apoptotic signaling pathway GO:0097190 27 0.011
negative regulation of signal transduction GO:0009968 83 0.011
estrous cycle phase GO:0060206 15 0.011
regulation of locomotion GO:0040012 148 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
feeding behavior GO:0007631 53 0.011
regulation of system process GO:0044057 208 0.011
meiotic cell cycle process GO:1903046 3 0.010
kidney development GO:0001822 67 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
adult locomotory behavior GO:0008344 4 0.010
immune response GO:0006955 104 0.010
response to nutrient GO:0007584 248 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
male sex differentiation GO:0046661 64 0.010
localization of cell GO:0051674 202 0.010
brain development GO:0007420 247 0.010

Pds5b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025