Rattus norvegicus

223 known processes

Pdx1

pancreatic and duodenal homeobox 1

(Aliases: Ipf1,Idx1,Stf1)

Pdx1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to oxygen containing compound GO:1901701 386 0.179
cellular response to organonitrogen compound GO:0071417 197 0.162
response to corticosteroid GO:0031960 235 0.142
regulation of calcium ion dependent exocytosis GO:0017158 11 0.141
response to peptide GO:1901652 292 0.114
response to molecule of bacterial origin GO:0002237 194 0.108
behavior GO:0007610 205 0.101
response to bacterium GO:0009617 200 0.097
cellular chemical homeostasis GO:0055082 247 0.089
positive regulation of signaling GO:0023056 270 0.089
regulation of phosphorus metabolic process GO:0051174 349 0.087
response to nutrient GO:0007584 248 0.085
ion homeostasis GO:0050801 212 0.083
chemical homeostasis GO:0048878 292 0.081
catabolic process GO:0009056 351 0.076
response to extracellular stimulus GO:0009991 380 0.072
cellular homeostasis GO:0019725 252 0.068
cellular response to external stimulus GO:0071496 118 0.066
cellular catabolic process GO:0044248 295 0.064
homeostatic process GO:0042592 331 0.064
cation homeostasis GO:0055080 195 0.061
regulation of peptide secretion GO:0002791 82 0.061
organic substance catabolic process GO:1901575 316 0.060
response to decreased oxygen levels GO:0036293 237 0.060
protein heterooligomerization GO:0051291 89 0.058
positive regulation of cell communication GO:0010647 271 0.058
response to metal ion GO:0010038 253 0.053
cellular ion homeostasis GO:0006873 184 0.053
positive regulation of transport GO:0051050 245 0.052
cellular response to lipid GO:0071396 201 0.051
response to lipopolysaccharide GO:0032496 191 0.051
response to oxygen levels GO:0070482 265 0.047
regulation of protein modification process GO:0031399 194 0.046
cellular calcium ion homeostasis GO:0006874 160 0.045
cytosolic calcium ion homeostasis GO:0051480 140 0.043
vesicle mediated transport GO:0016192 181 0.043
response to wounding GO:0009611 254 0.043
purine containing compound biosynthetic process GO:0072522 85 0.041
carboxylic acid metabolic process GO:0019752 289 0.040
divalent inorganic cation homeostasis GO:0072507 165 0.039
regulation of phosphate metabolic process GO:0019220 349 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
response to nutrient levels GO:0031667 370 0.037
immune response GO:0006955 104 0.036
response to organophosphorus GO:0046683 102 0.035
cellular ketone metabolic process GO:0042180 51 0.035
cellular cation homeostasis GO:0030003 180 0.035
synaptic transmission GO:0007268 235 0.035
central nervous system development GO:0007417 311 0.035
cellular amide metabolic process GO:0043603 44 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
cellular lipid metabolic process GO:0044255 208 0.034
protein homooligomerization GO:0051260 91 0.033
regulation of peptide transport GO:0090087 87 0.033
response to hypoxia GO:0001666 231 0.033
negative regulation of cellular component organization GO:0051129 83 0.032
cellular metal ion homeostasis GO:0006875 172 0.032
positive regulation of signal transduction GO:0009967 175 0.031
response to purine containing compound GO:0014074 126 0.030
response to biotic stimulus GO:0009607 226 0.030
response to estrogen GO:0043627 232 0.030
regulation of nervous system development GO:0051960 264 0.030
synapse assembly GO:0007416 29 0.030
organophosphate metabolic process GO:0019637 370 0.029
cellular component biogenesis GO:0044085 368 0.029
calcium ion dependent exocytosis GO:0017156 16 0.029
inflammatory response GO:0006954 150 0.029
response to alkaloid GO:0043279 132 0.029
secretion by cell GO:0032940 248 0.029
divalent metal ion transport GO:0070838 132 0.029
cellular response to organic cyclic compound GO:0071407 202 0.028
regulation of lipid metabolic process GO:0019216 68 0.028
regulation of protein metabolic process GO:0051246 289 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
negative regulation of nervous system development GO:0051961 79 0.028
organic acid metabolic process GO:0006082 292 0.027
positive regulation of apoptotic process GO:0043065 154 0.027
regulation of programmed cell death GO:0043067 341 0.027
reproductive process GO:0022414 372 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
positive regulation of peptide hormone secretion GO:0090277 50 0.027
organophosphate biosynthetic process GO:0090407 143 0.026
calcium ion homeostasis GO:0055074 162 0.026
protein oligomerization GO:0051259 191 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
response to glucocorticoid GO:0051384 223 0.026
defense response GO:0006952 194 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
response to external biotic stimulus GO:0043207 221 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
multicellular organism reproduction GO:0032504 233 0.023
purine nucleotide biosynthetic process GO:0006164 83 0.023
cellular hormone metabolic process GO:0034754 49 0.023
metal ion homeostasis GO:0055065 186 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
small molecule catabolic process GO:0044282 59 0.023
programmed cell death GO:0012501 392 0.022
cellular component assembly GO:0022607 360 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
heterocycle catabolic process GO:0046700 167 0.021
response to peptide hormone GO:0043434 278 0.021
response to hexose GO:0009746 144 0.021
purine containing compound metabolic process GO:0072521 253 0.021
single organism biosynthetic process GO:0044711 342 0.020
neuron death GO:0070997 127 0.020
regulation of hormone secretion GO:0046883 106 0.020
divalent inorganic cation transport GO:0072511 134 0.020
anterior posterior pattern specification GO:0009952 1 0.020
positive regulation of cell death GO:0010942 184 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
ion transmembrane transport GO:0034220 365 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
positive regulation of programmed cell death GO:0043068 157 0.019
regulation of calcium ion transport GO:0051924 77 0.019
negative regulation of transport GO:0051051 136 0.019
immune system process GO:0002376 204 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
nucleoside phosphate biosynthetic process GO:1901293 102 0.019
rna biosynthetic process GO:0032774 380 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
reproduction GO:0000003 245 0.019
single organism catabolic process GO:0044712 283 0.019
negative regulation of molecular function GO:0044092 133 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
regulation of cell differentiation GO:0045595 320 0.018
rna metabolic process GO:0016070 406 0.018
regulation of cellular localization GO:0060341 263 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
response to monosaccharide GO:0034284 159 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
neurological system process GO:0050877 219 0.018
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
cell cell signaling GO:0007267 335 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
oxoacid metabolic process GO:0043436 290 0.017
smooth muscle cell proliferation GO:0048659 77 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
grooming behavior GO:0007625 4 0.016
single organism reproductive process GO:0044702 297 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
regulation of transmembrane transport GO:0034762 122 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
response to reactive oxygen species GO:0000302 120 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
nucleoside metabolic process GO:0009116 179 0.016
regulation of cytokine production GO:0001817 56 0.016
innate immune response GO:0045087 35 0.016
phosphatidylinositol dephosphorylation GO:0046856 4 0.016
organic cyclic compound catabolic process GO:1901361 175 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
cellular amine metabolic process GO:0044106 38 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cellular response to peptide GO:1901653 133 0.015
response to growth factor GO:0070848 189 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
cognition GO:0050890 92 0.015
calcium ion transport GO:0006816 131 0.015
protein phosphorylation GO:0006468 345 0.015
regulation of apoptotic process GO:0042981 335 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
response to insulin GO:0032868 133 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
apoptotic process GO:0006915 381 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
amine metabolic process GO:0009308 38 0.014
response to increased oxygen levels GO:0036296 45 0.014
nucleotide metabolic process GO:0009117 279 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
negative regulation of innate immune response GO:0045824 4 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
regulation of catalytic activity GO:0050790 304 0.014
protein complex subunit organization GO:0071822 302 0.014
peptide hormone secretion GO:0030072 84 0.014
blood circulation GO:0008015 183 0.013
regulation of molecular function GO:0065009 398 0.013
aging GO:0007568 241 0.013
axis specification GO:0009798 4 0.013
response to inorganic substance GO:0010035 377 0.013
response to ketone GO:1901654 182 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
single organism behavior GO:0044708 130 0.013
response to glucose GO:0009749 136 0.013
regulation of cellular component organization GO:0051128 368 0.013
organ regeneration GO:0031100 101 0.013
negative regulation of secretion GO:0051048 82 0.013
protein complex biogenesis GO:0070271 263 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
positive regulation of peptide secretion GO:0002793 52 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
transmembrane transport GO:0055085 412 0.013
intracellular signal transduction GO:0035556 314 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
positive regulation of hormone secretion GO:0046887 65 0.012
learning or memory GO:0007611 90 0.012
regulation of organelle organization GO:0033043 80 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
positive regulation of nervous system development GO:0051962 178 0.012
hormone secretion GO:0046879 115 0.012
protein complex assembly GO:0006461 263 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
response to toxic substance GO:0009636 133 0.012
regulation of heart contraction GO:0008016 48 0.011
purine ribonucleoside biosynthetic process GO:0046129 21 0.011
macromolecular complex assembly GO:0065003 273 0.011
nucleotide catabolic process GO:0009166 139 0.011
positive regulation of blood circulation GO:1903524 65 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
cardiovascular system development GO:0072358 134 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
second messenger mediated signaling GO:0019932 51 0.011
response to radiation GO:0009314 137 0.011
eye morphogenesis GO:0048592 4 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
exocytosis GO:0006887 60 0.011
single organism organelle organization GO:1902589 180 0.011
glycerolipid metabolic process GO:0046486 67 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
response to antibiotic GO:0046677 39 0.011
cofactor metabolic process GO:0051186 95 0.011
peptide secretion GO:0002790 86 0.011
hormone metabolic process GO:0042445 69 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
aromatic compound catabolic process GO:0019439 168 0.011
cellular response to alcohol GO:0097306 87 0.011
regulation of exocytosis GO:0017157 37 0.011
response to acid chemical GO:0001101 222 0.011
positive regulation of molecular function GO:0044093 230 0.011
regulation of cell development GO:0060284 263 0.010
steroid metabolic process GO:0008202 73 0.010
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.010
negative regulation of immune response GO:0050777 15 0.010
brain development GO:0007420 247 0.010
multi organism reproductive process GO:0044703 262 0.010
regulation of metanephros development GO:0072215 4 0.010
nitrogen compound transport GO:0071705 229 0.010
proteolysis GO:0006508 175 0.010
regulation of metal ion transport GO:0010959 118 0.010
negative regulation of vesicle fusion GO:0031339 2 0.010

Pdx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014