Rattus norvegicus

90 known processes

Pfkfb1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

(Aliases: Pfkfb01,PFRX)

Pfkfb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.801
Rat
organic acid metabolic process GO:0006082 292 0.557
Rat
cellular lipid metabolic process GO:0044255 208 0.488
monocarboxylic acid metabolic process GO:0032787 152 0.406
Rat
carboxylic acid metabolic process GO:0019752 289 0.400
Rat
cellular response to stress GO:0033554 269 0.365
neuron differentiation GO:0030182 368 0.224
response to nutrient levels GO:0031667 370 0.214
response to purine containing compound GO:0014074 126 0.203
response to peptide GO:1901652 292 0.202
oxidation reduction process GO:0055114 304 0.197
response to extracellular stimulus GO:0009991 380 0.195
lipid metabolic process GO:0006629 283 0.188
response to monosaccharide GO:0034284 159 0.174
Rat
response to biotic stimulus GO:0009607 226 0.172
cellular response to oxygen containing compound GO:1901701 386 0.166
organonitrogen compound biosynthetic process GO:1901566 167 0.164
response to organophosphorus GO:0046683 102 0.147
steroid metabolic process GO:0008202 73 0.144
positive regulation of multicellular organismal process GO:0051240 387 0.142
cofactor metabolic process GO:0051186 95 0.124
single organism biosynthetic process GO:0044711 342 0.122
regulation of apoptotic process GO:0042981 335 0.121
cellular response to organic cyclic compound GO:0071407 202 0.120
female pregnancy GO:0007565 122 0.120
defense response GO:0006952 194 0.119
calcitriol biosynthetic process from calciol GO:0036378 2 0.117
cellular response to endogenous stimulus GO:0071495 377 0.117
response to ketone GO:1901654 182 0.115
response to nutrient GO:0007584 248 0.115
catabolic process GO:0009056 351 0.114
Rat
regulation of programmed cell death GO:0043067 341 0.113
gland development GO:0048732 155 0.110
response to peptide hormone GO:0043434 278 0.107
reproductive process GO:0022414 372 0.105
positive regulation of cell communication GO:0010647 271 0.103
Rat
response to inorganic substance GO:0010035 377 0.101
carbohydrate derivative metabolic process GO:1901135 346 0.098
cellular catabolic process GO:0044248 295 0.098
response to alkaloid GO:0043279 132 0.097
multi organism reproductive process GO:0044703 262 0.093
regulation of cellular protein metabolic process GO:0032268 267 0.090
regulation of cellular ketone metabolic process GO:0010565 27 0.089
regulation of molecular function GO:0065009 398 0.089
intracellular signal transduction GO:0035556 314 0.085
regulation of cellular component organization GO:0051128 368 0.084
response to glucose GO:0009749 136 0.083
Rat
fatty acid metabolic process GO:0006631 99 0.083
negative regulation of programmed cell death GO:0043069 183 0.081
cellular response to nitrogen compound GO:1901699 210 0.081
protein phosphorylation GO:0006468 345 0.080
lipid biosynthetic process GO:0008610 128 0.079
response to camp GO:0051591 91 0.079
positive regulation of response to stimulus GO:0048584 285 0.076
regulation of cell differentiation GO:0045595 320 0.074
cellular response to organonitrogen compound GO:0071417 197 0.074
regulation of protein metabolic process GO:0051246 289 0.074
multicellular organism reproduction GO:0032504 233 0.072
regulation of catalytic activity GO:0050790 304 0.072
regulation of phosphorylation GO:0042325 248 0.071
circulatory system process GO:0003013 183 0.070
response to acid chemical GO:0001101 222 0.069
nucleobase containing small molecule metabolic process GO:0055086 316 0.069
regeneration GO:0031099 163 0.069
multicellular organismal reproductive process GO:0048609 233 0.069
single organism reproductive process GO:0044702 297 0.068
growth GO:0040007 165 0.067
programmed cell death GO:0012501 392 0.067
response to hexose GO:0009746 144 0.065
Rat
response to estrogen GO:0043627 232 0.065
apoptotic process GO:0006915 381 0.064
negative regulation of metabolic process GO:0009892 331 0.063
locomotion GO:0040011 237 0.063
regulation of multicellular organismal development GO:2000026 376 0.063
response to carbohydrate GO:0009743 183 0.062
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.062
reactive nitrogen species metabolic process GO:2001057 1 0.061
tissue development GO:0009888 252 0.061
regulation of rna metabolic process GO:0051252 391 0.060
cellular response to peptide hormone stimulus GO:0071375 120 0.060
chemical homeostasis GO:0048878 292 0.060
neurological system process GO:0050877 219 0.059
organic acid biosynthetic process GO:0016053 83 0.059
regulation of transferase activity GO:0051338 123 0.058
carbohydrate metabolic process GO:0005975 130 0.058
regulation of cell development GO:0060284 263 0.058
response to insulin GO:0032868 133 0.058
response to oxidative stress GO:0006979 186 0.057
cellular ketone metabolic process GO:0042180 51 0.057
alpha amino acid metabolic process GO:1901605 71 0.057
macromolecule localization GO:0033036 252 0.056
macromolecular complex assembly GO:0065003 273 0.055
regulation of rna biosynthetic process GO:2001141 381 0.055
protein complex assembly GO:0006461 263 0.055
reproduction GO:0000003 245 0.054
positive regulation of developmental process GO:0051094 283 0.052
blood circulation GO:0008015 183 0.052
response to lipopolysaccharide GO:0032496 191 0.052
response to glucocorticoid GO:0051384 223 0.052
anatomical structure morphogenesis GO:0009653 298 0.052
regulation of signal transduction GO:0009966 318 0.051
response to hypoxia GO:0001666 231 0.051
stress activated protein kinase signaling cascade GO:0031098 37 0.050
regulation of transcription dna templated GO:0006355 374 0.050
protein maturation GO:0051604 68 0.050
positive regulation of rna biosynthetic process GO:1902680 197 0.050
reproductive system development GO:0061458 128 0.050
positive regulation of biosynthetic process GO:0009891 319 0.050
organic substance catabolic process GO:1901575 316 0.050
Rat
regulation of cell proliferation GO:0042127 359 0.049
neuron development GO:0048666 286 0.048
drug catabolic process GO:0042737 1 0.048
organic hydroxy compound biosynthetic process GO:1901617 51 0.048
positive regulation of rna metabolic process GO:0051254 203 0.048
regulation of cellular amino acid metabolic process GO:0006521 2 0.048
rna biosynthetic process GO:0032774 380 0.047
head development GO:0060322 247 0.047
Rat
energy derivation by oxidation of organic compounds GO:0015980 46 0.047
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.046
multi multicellular organism process GO:0044706 138 0.046
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
signal transduction by phosphorylation GO:0023014 144 0.046
cellular response to fluid shear stress GO:0071498 4 0.045
response to molecule of bacterial origin GO:0002237 194 0.045
cellular hormone metabolic process GO:0034754 49 0.045
negative regulation of multicellular organismal process GO:0051241 203 0.045
response to oxygen levels GO:0070482 265 0.045
proteolysis GO:0006508 175 0.045
cellular amino acid metabolic process GO:0006520 107 0.045
homeostatic process GO:0042592 331 0.045
cell projection organization GO:0030030 302 0.044
purine nucleoside metabolic process GO:0042278 169 0.044
response to external biotic stimulus GO:0043207 221 0.044
immune system process GO:0002376 204 0.043
nucleotide metabolic process GO:0009117 279 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
cellular chemical homeostasis GO:0055082 247 0.042
sexual reproduction GO:0019953 148 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
negative regulation of gene expression GO:0010629 199 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.042
response to corticosteroid GO:0031960 235 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
response to decreased oxygen levels GO:0036293 237 0.041
rhythmic process GO:0048511 156 0.040
response to wounding GO:0009611 254 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.040
glycosyl compound metabolic process GO:1901657 182 0.039
inflammatory response GO:0006954 150 0.039
small molecule catabolic process GO:0044282 59 0.038
organophosphate metabolic process GO:0019637 370 0.038
mapk cascade GO:0000165 140 0.037
reactive oxygen species metabolic process GO:0072593 37 0.037
purine containing compound metabolic process GO:0072521 253 0.037
small molecule biosynthetic process GO:0044283 124 0.037
alkaloid metabolic process GO:0009820 3 0.037
positive regulation of cell differentiation GO:0045597 217 0.037
response to fatty acid GO:0070542 65 0.037
regulation of nervous system development GO:0051960 264 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.036
dicarboxylic acid metabolic process GO:0043648 42 0.036
response to amine GO:0014075 46 0.035
positive regulation of transcription dna templated GO:0045893 197 0.035
carbohydrate homeostasis GO:0033500 75 0.035
chromosome segregation GO:0007059 2 0.035
single organism catabolic process GO:0044712 283 0.035
Rat
cellular response to abiotic stimulus GO:0071214 85 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
cell activation GO:0001775 97 0.035
positive regulation of phosphate metabolic process GO:0045937 262 0.034
cellular ion homeostasis GO:0006873 184 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
developmental process involved in reproduction GO:0003006 159 0.034
unsaturated fatty acid metabolic process GO:0033559 39 0.034
response to reactive oxygen species GO:0000302 120 0.034
hepaticobiliary system development GO:0061008 90 0.034
regulation of anatomical structure size GO:0090066 135 0.034
alpha amino acid biosynthetic process GO:1901607 23 0.034
regulation of hormone levels GO:0010817 187 0.034
Rat
regulation of neurogenesis GO:0050767 247 0.034
organ regeneration GO:0031100 101 0.034
regulation of lipid metabolic process GO:0019216 68 0.033
cellular homeostasis GO:0019725 252 0.033
response to metal ion GO:0010038 253 0.033
central nervous system development GO:0007417 311 0.033
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.033
liver development GO:0001889 90 0.033
neuron projection development GO:0031175 273 0.033
regulation of cell cycle GO:0051726 73 0.032
regulation of mapk cascade GO:0043408 116 0.032
cellular response to insulin stimulus GO:0032869 81 0.032
regulation of response to stress GO:0080134 126 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
ion homeostasis GO:0050801 212 0.032
negative regulation of cell proliferation GO:0008285 119 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
cholesterol homeostasis GO:0042632 3 0.031
negative regulation of apoptotic process GO:0043066 181 0.031
behavior GO:0007610 205 0.030
regulation of tube size GO:0035150 89 0.030
neuron death GO:0070997 127 0.030
cell migration GO:0016477 197 0.030
isoprenoid metabolic process GO:0006720 45 0.030
heart morphogenesis GO:0003007 3 0.029
response to bacterium GO:0009617 200 0.029
protein oligomerization GO:0051259 191 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
aging GO:0007568 241 0.029
generation of precursor metabolites and energy GO:0006091 62 0.028
positive regulation of extracellular matrix organization GO:1903055 4 0.028
single organism cellular localization GO:1902580 102 0.028
positive regulation of nervous system development GO:0051962 178 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
cellular response to oxidative stress GO:0034599 76 0.028
cellular component biogenesis GO:0044085 368 0.028
organelle organization GO:0006996 266 0.028
cell adhesion GO:0007155 110 0.028
secondary alcohol metabolic process GO:1902652 2 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.027
regulation of system process GO:0044057 208 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
cellular amine metabolic process GO:0044106 38 0.027
trichloroethylene metabolic process GO:0018979 1 0.027
exogenous drug catabolic process GO:0042738 1 0.027
response to toxic substance GO:0009636 133 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
positive regulation of programmed cell death GO:0043068 157 0.026
naphthalene metabolic process GO:0018931 2 0.025
stress activated mapk cascade GO:0051403 35 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
negative regulation of cell death GO:0060548 229 0.025
regulation of neuron differentiation GO:0045664 208 0.025
muscle structure development GO:0061061 87 0.025
nucleic acid templated transcription GO:0097659 379 0.024
regulation of hydrolase activity GO:0051336 143 0.024
macromolecule catabolic process GO:0009057 58 0.024
glucose homeostasis GO:0042593 75 0.024
drug metabolic process GO:0017144 11 0.024
response to estradiol GO:0032355 164 0.024
regulation of response to wounding GO:1903034 69 0.024
transcription dna templated GO:0006351 377 0.024
biological adhesion GO:0022610 110 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
regulation of protein maturation GO:1903317 50 0.024
positive regulation of cell death GO:0010942 184 0.024
rna metabolic process GO:0016070 406 0.024
positive regulation of gene expression GO:0010628 244 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.023
muscle cell proliferation GO:0033002 84 0.023
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
coenzyme metabolic process GO:0006732 86 0.023
regulation of secretion GO:0051046 224 0.023
Rat
cellular carbohydrate metabolic process GO:0044262 72 0.023
cellular response to lipid GO:0071396 201 0.023
protein homooligomerization GO:0051260 91 0.022
cellular response to interleukin 1 GO:0071347 37 0.022
amine metabolic process GO:0009308 38 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
vitamin d metabolic process GO:0042359 4 0.022
negative regulation of signaling GO:0023057 157 0.022
protein localization GO:0008104 191 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
divalent metal ion transport GO:0070838 132 0.022
cell motility GO:0048870 202 0.022
regulation of cellular response to stress GO:0080135 49 0.022
reactive oxygen species biosynthetic process GO:1903409 8 0.022
glucan metabolic process GO:0044042 23 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
immune system development GO:0002520 41 0.021
testosterone biosynthetic process GO:0061370 5 0.021
reproductive structure development GO:0048608 128 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
cellular component movement GO:0006928 248 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
response to mechanical stimulus GO:0009612 134 0.021
regulation of immune system process GO:0002682 123 0.021
cardiovascular system development GO:0072358 134 0.021
negative regulation of molecular function GO:0044092 133 0.020
regulation of blood pressure GO:0008217 83 0.020
developmental growth GO:0048589 100 0.020
positive regulation of signal transduction GO:0009967 175 0.020
positive regulation of molecular function GO:0044093 230 0.020
regulation of growth GO:0040008 105 0.020
sulfur compound metabolic process GO:0006790 70 0.020
multicellular organism growth GO:0035264 1 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
positive regulation of cell development GO:0010720 176 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
regulation of kinase activity GO:0043549 117 0.019
regulation of blood circulation GO:1903522 110 0.019
positive regulation of signaling GO:0023056 270 0.019
Rat
regulation of ossification GO:0030278 32 0.019
nucleoside monophosphate metabolic process GO:0009123 93 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
cellular response to peptide GO:1901653 133 0.019
regulation of protein kinase activity GO:0045859 105 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
cell cycle GO:0007049 101 0.019
regulation of protein processing GO:0070613 50 0.019
response to starvation GO:0042594 59 0.019
glycogen metabolic process GO:0005977 23 0.018
regulation of homeostatic process GO:0032844 101 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
erythrocyte differentiation GO:0030218 1 0.018
response to calcium ion GO:0051592 59 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
vitamin biosynthetic process GO:0009110 3 0.018
heart development GO:0007507 72 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
response to ethanol GO:0045471 162 0.018
regulation of neuron projection development GO:0010975 161 0.018
regulation of cell projection organization GO:0031344 175 0.018
protein processing GO:0016485 68 0.018
positive regulation of protein modification process GO:0031401 142 0.018
brain development GO:0007420 247 0.018
Rat
circulatory system development GO:0072359 134 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.018
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.018
fatty acid derivative metabolic process GO:1901568 38 0.017
gamete generation GO:0007276 124 0.017
organic anion transport GO:0015711 132 0.017
positive regulation of secretion GO:0051047 140 0.017
Rat
negative regulation of signal transduction GO:0009968 83 0.017
response to activity GO:0014823 73 0.017
vitamin d3 metabolic process GO:0070640 2 0.017
protein complex subunit organization GO:0071822 302 0.017
isoquinoline alkaloid metabolic process GO:0033076 2 0.017
organ morphogenesis GO:0009887 75 0.017
single organism intracellular transport GO:1902582 166 0.017
glycerolipid metabolic process GO:0046486 67 0.017
negative regulation of developmental process GO:0051093 125 0.017
polysaccharide metabolic process GO:0005976 25 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
anion transport GO:0006820 178 0.016
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
histone h3 acetylation GO:0043966 2 0.016
purine ribonucleotide biosynthetic process GO:0009152 81 0.016
regulation of blood vessel size GO:0050880 89 0.016
regulation of protein modification process GO:0031399 194 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
response to cytokine GO:0034097 215 0.016
sex differentiation GO:0007548 113 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
secretion GO:0046903 307 0.016
Rat
regulation of stress activated mapk cascade GO:0032872 23 0.016
cellular protein localization GO:0034613 122 0.016
response to other organism GO:0051707 220 0.016
negative regulation of catalytic activity GO:0043086 103 0.015
fat soluble vitamin biosynthetic process GO:0042362 2 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
regulation of ion transport GO:0043269 245 0.015
cellular response to reactive oxygen species GO:0034614 55 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
naphthalene containing compound metabolic process GO:0090420 2 0.015
positive regulation of transport GO:0051050 245 0.015
Rat
protein complex biogenesis GO:0070271 263 0.015
cellular alcohol biosynthetic process GO:0044108 2 0.015
regulation of neuron death GO:1901214 115 0.015
negative regulation of protein maturation GO:1903318 47 0.015
negative regulation of protein processing GO:0010955 47 0.015
monosaccharide metabolic process GO:0005996 61 0.015
pyridine containing compound metabolic process GO:0072524 32 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.014
Rat
maternal process involved in female pregnancy GO:0060135 38 0.014
cellular cation homeostasis GO:0030003 180 0.014
metal ion homeostasis GO:0055065 186 0.014
nucleoside metabolic process GO:0009116 179 0.014
positive regulation of blood circulation GO:1903524 65 0.014
negative regulation of cell communication GO:0010648 158 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
hormone metabolic process GO:0042445 69 0.014
single organism nuclear import GO:1902593 35 0.014
alcohol biosynthetic process GO:0046165 38 0.014
establishment of protein localization to organelle GO:0072594 44 0.014
chlorinated hydrocarbon metabolic process GO:0042196 4 0.014
carbohydrate biosynthetic process GO:0016051 42 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
jak stat cascade GO:0007259 26 0.014
response to growth factor GO:0070848 189 0.014
intracellular transport GO:0046907 185 0.014
regulation of response to external stimulus GO:0032101 106 0.014
cellular response to monosaccharide stimulus GO:0071326 67 0.014
regulation of cell migration GO:0030334 128 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.013
regulation of locomotion GO:0040012 148 0.013
vesicle mediated transport GO:0016192 181 0.013
cellular macromolecule localization GO:0070727 122 0.013
secondary metabolic process GO:0019748 15 0.013
vasoconstriction GO:0042310 54 0.013
regulation of defense response GO:0031347 68 0.013
amine transport GO:0015837 57 0.013
retinoid metabolic process GO:0001523 24 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.013
protein targeting GO:0006605 61 0.013
response to mercury ion GO:0046689 15 0.013
negative regulation of proteolysis GO:0045861 41 0.013
cellular response to glucose stimulus GO:0071333 65 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
vascular process in circulatory system GO:0003018 96 0.013
neuron apoptotic process GO:0051402 88 0.013
ras protein signal transduction GO:0007265 29 0.012
localization of cell GO:0051674 202 0.012
nicotinamide nucleotide metabolic process GO:0046496 28 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
metal ion transport GO:0030001 289 0.012
response to amphetamine GO:0001975 25 0.012
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.012
alcohol metabolic process GO:0006066 77 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
immune response GO:0006955 104 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
intracellular protein transport GO:0006886 79 0.012
diterpenoid metabolic process GO:0016101 33 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
response to interleukin 1 GO:0070555 55 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
regulation of catabolic process GO:0009894 113 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
multicellular organismal signaling GO:0035637 44 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
oxidative demethylation GO:0070989 2 0.012
progesterone biosynthetic process GO:0006701 3 0.012
response to insecticide GO:0017085 21 0.012
response to xenobiotic stimulus GO:0009410 23 0.012
carboxylic acid catabolic process GO:0046395 49 0.012
dephosphorylation GO:0016311 98 0.012
organic acid transport GO:0015849 116 0.011
lipid catabolic process GO:0016042 46 0.011
response to testosterone GO:0033574 55 0.011
terpenoid metabolic process GO:0006721 37 0.011
regulation of proteolysis GO:0030162 66 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
transmission of nerve impulse GO:0019226 42 0.011
ossification GO:0001503 70 0.011
pteridine containing compound metabolic process GO:0042558 14 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
negative regulation of response to external stimulus GO:0032102 37 0.011
regulation of cellular localization GO:0060341 263 0.011
Rat
gonad development GO:0008406 104 0.011
protein localization to organelle GO:0033365 57 0.011
lipid storage GO:0019915 1 0.011
cellular component assembly GO:0022607 360 0.011
sensory perception GO:0007600 101 0.011
protein import into nucleus GO:0006606 35 0.011
vitamin d biosynthetic process GO:0042368 2 0.011
organic hydroxy compound transport GO:0015850 77 0.011
embryo development GO:0009790 49 0.011
alditol metabolic process GO:0019400 4 0.011
mitotic sister chromatid separation GO:0051306 1 0.011
androgen biosynthetic process GO:0006702 10 0.011
striated muscle tissue development GO:0014706 58 0.011
aromatic compound catabolic process GO:0019439 168 0.011
b cell differentiation GO:0030183 2 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
cellular glucose homeostasis GO:0001678 66 0.011
regulation of carbohydrate metabolic process GO:0006109 41 0.010
response to cadmium ion GO:0046686 35 0.010
lauric acid metabolic process GO:0048252 4 0.010
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
negative regulation of growth GO:0045926 37 0.010
response to hydrogen peroxide GO:0042542 89 0.010
positive regulation of transferase activity GO:0051347 81 0.010
response to corticosterone GO:0051412 40 0.010
energy reserve metabolic process GO:0006112 25 0.010
cation transport GO:0006812 382 0.010
response to axon injury GO:0048678 59 0.010
cellular polysaccharide metabolic process GO:0044264 23 0.010

Pfkfb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
obesity DOID:9970 0 0.034
acquired metabolic disease DOID:0060158 0 0.034
disease of metabolism DOID:0014667 0 0.034
nutrition disease DOID:374 0 0.034
overnutrition DOID:654 0 0.034
disease of anatomical entity DOID:7 0 0.026
musculoskeletal system disease DOID:17 0 0.026
central nervous system disease DOID:331 0 0.022
nervous system disease DOID:863 0 0.022
cardiovascular system disease DOID:1287 0 0.010
vascular disease DOID:178 0 0.010
artery disease DOID:0050828 0 0.010
hypertension DOID:10763 0 0.010