Rattus norvegicus

125 known processes

Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

(Aliases: RH2K)

Pfkfb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle system process GO:0003012 115 0.749
cytosolic calcium ion homeostasis GO:0051480 140 0.728
calcium ion homeostasis GO:0055074 162 0.717
regulation of ion transport GO:0043269 245 0.590
heart process GO:0003015 57 0.589
g protein coupled receptor signaling pathway GO:0007186 242 0.520
cellular metal ion homeostasis GO:0006875 172 0.478
regulation of rna metabolic process GO:0051252 391 0.458
regulation of phosphorus metabolic process GO:0051174 349 0.453
divalent inorganic cation homeostasis GO:0072507 165 0.440
cellular calcium ion homeostasis GO:0006874 160 0.423
vesicle mediated transport GO:0016192 181 0.419
transmembrane transport GO:0055085 412 0.418
heart contraction GO:0060047 57 0.404
positive regulation of transport GO:0051050 245 0.398
metal ion transport GO:0030001 289 0.388
homeostatic process GO:0042592 331 0.387
divalent metal ion transport GO:0070838 132 0.382
calcium ion import GO:0070509 22 0.374
metal ion homeostasis GO:0055065 186 0.359
secretion by cell GO:0032940 248 0.341
cellular cation homeostasis GO:0030003 180 0.338
positive regulation of signal transduction GO:0009967 175 0.335
regulation of calcium ion transport GO:0051924 77 0.315
cation transmembrane transport GO:0098655 263 0.314
regulation of metal ion transport GO:0010959 118 0.313
cognition GO:0050890 92 0.311
regulation of secretion GO:0051046 224 0.310
mapk cascade GO:0000165 140 0.302
cellular divalent inorganic cation homeostasis GO:0072503 162 0.301
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.301
learning or memory GO:0007611 90 0.289
positive regulation of secretion by cell GO:1903532 128 0.288
actin filament based process GO:0030029 86 0.277
positive regulation of cell communication GO:0010647 271 0.267
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.266
intracellular signal transduction GO:0035556 314 0.260
divalent inorganic cation transport GO:0072511 134 0.259
multicellular organism reproduction GO:0032504 233 0.252
cellular chemical homeostasis GO:0055082 247 0.252
enzyme linked receptor protein signaling pathway GO:0007167 116 0.252
negative regulation of cellular biosynthetic process GO:0031327 161 0.242
blood circulation GO:0008015 183 0.233
regulation of system process GO:0044057 208 0.230
secretion GO:0046903 307 0.230
cation transport GO:0006812 382 0.219
hormone mediated signaling pathway GO:0009755 23 0.219
negative regulation of rna metabolic process GO:0051253 123 0.217
carbohydrate derivative metabolic process GO:1901135 346 0.216
cation homeostasis GO:0055080 195 0.214
cellular response to oxygen containing compound GO:1901701 386 0.202
cell cell signaling GO:0007267 335 0.201
negative regulation of biosynthetic process GO:0009890 168 0.200
ion transmembrane transport GO:0034220 365 0.196
regulation of transcription dna templated GO:0006355 374 0.194
cellular ion homeostasis GO:0006873 184 0.194
single organism behavior GO:0044708 130 0.193
regulation of nucleic acid templated transcription GO:1903506 380 0.177
regulation of mapk cascade GO:0043408 116 0.175
regulation of rna biosynthetic process GO:2001141 381 0.173
signal transduction by phosphorylation GO:0023014 144 0.173
cyclic nucleotide biosynthetic process GO:0009190 63 0.172
neuron development GO:0048666 286 0.172
neuron projection morphogenesis GO:0048812 122 0.170
phototransduction visible light GO:0007603 2 0.169
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.167
single organism biosynthetic process GO:0044711 342 0.166
rna biosynthetic process GO:0032774 380 0.165
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.164
calcium ion transport GO:0006816 131 0.163
regulation of muscle contraction GO:0006937 53 0.163
cellular homeostasis GO:0019725 252 0.162
neurological system process GO:0050877 219 0.161
regulation of blood vessel size GO:0050880 89 0.154
positive regulation of transcription dna templated GO:0045893 197 0.153
protein localization GO:0008104 191 0.149
signal release GO:0023061 145 0.148
single organism intracellular transport GO:1902582 166 0.147
protein transport GO:0015031 132 0.146
regulation of signal transduction GO:0009966 318 0.146
rna metabolic process GO:0016070 406 0.146
transcription from rna polymerase ii promoter GO:0006366 252 0.145
head development GO:0060322 247 0.145
Rat
response to hypoxia GO:0001666 231 0.143
cellular component assembly GO:0022607 360 0.142
cellular carbohydrate metabolic process GO:0044262 72 0.141
organelle organization GO:0006996 266 0.140
cellular response to stress GO:0033554 269 0.140
cell part morphogenesis GO:0032990 123 0.139
memory GO:0007613 54 0.138
cell morphogenesis GO:0000902 142 0.137
endocytosis GO:0006897 84 0.136
regulation of muscle system process GO:0090257 79 0.136
cellular component biogenesis GO:0044085 368 0.136
circulatory system process GO:0003013 183 0.134
regulation of heart contraction GO:0008016 48 0.134
morphogenesis of an epithelium GO:0002009 20 0.134
ion homeostasis GO:0050801 212 0.134
regulation of intracellular signal transduction GO:1902531 218 0.133
nucleic acid templated transcription GO:0097659 379 0.132
vascular process in circulatory system GO:0003018 96 0.131
neuron projection development GO:0031175 273 0.130
multicellular organismal reproductive process GO:0048609 233 0.130
regulation of vesicle mediated transport GO:0060627 81 0.128
regulation of phosphorylation GO:0042325 248 0.127
protein complex assembly GO:0006461 263 0.127
transcription dna templated GO:0006351 377 0.127
glutamate receptor signaling pathway GO:0007215 43 0.126
positive regulation of intracellular signal transduction GO:1902533 138 0.125
regulation of exocytosis GO:0017157 37 0.125
regulation of blood circulation GO:1903522 110 0.125
macromolecule localization GO:0033036 252 0.124
detection of visible light GO:0009584 3 0.123
positive regulation of biosynthetic process GO:0009891 319 0.121
negative regulation of metabolic process GO:0009892 331 0.118
regulation of behavior GO:0050795 61 0.118
neuron differentiation GO:0030182 368 0.117
rhythmic process GO:0048511 156 0.115
cellular response to nitrogen compound GO:1901699 210 0.115
cardiac muscle contraction GO:0060048 27 0.115
regulation of molecular function GO:0065009 398 0.113
brain development GO:0007420 247 0.111
Rat
cellular component movement GO:0006928 248 0.111
response to radiation GO:0009314 137 0.110
macromolecular complex subunit organization GO:0043933 339 0.110
chemical homeostasis GO:0048878 292 0.110
negative regulation of apoptotic process GO:0043066 181 0.109
renal sodium excretion GO:0035812 20 0.107
response to oxygen levels GO:0070482 265 0.105
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.105
cellular response to lipid GO:0071396 201 0.105
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.104
central nervous system development GO:0007417 311 0.104
Rat
striated muscle contraction GO:0006941 44 0.103
organophosphate biosynthetic process GO:0090407 143 0.102
positive regulation of mapk cascade GO:0043410 92 0.102
regulation of cellular component organization GO:0051128 368 0.102
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.099
negative regulation of macromolecule metabolic process GO:0010605 260 0.099
regulation of transmembrane transporter activity GO:0022898 49 0.099
cellular component morphogenesis GO:0032989 155 0.098
response to light stimulus GO:0009416 52 0.098
positive regulation of blood circulation GO:1903524 65 0.097
regulation of ion transmembrane transporter activity GO:0032412 48 0.097
positive regulation of synaptic transmission GO:0050806 62 0.096
cell type specific apoptotic process GO:0097285 134 0.095
regulation of transferase activity GO:0051338 123 0.094
prepulse inhibition GO:0060134 1 0.094
regulation of protein modification process GO:0031399 194 0.094
regulation of catecholamine secretion GO:0050433 32 0.094
response to decreased oxygen levels GO:0036293 237 0.092
regulation of anatomical structure size GO:0090066 135 0.090
regulation of multicellular organismal development GO:2000026 376 0.089
regulation of neuron apoptotic process GO:0043523 83 0.089
anterior posterior pattern specification GO:0009952 1 0.089
positive regulation of signaling GO:0023056 270 0.088
hormone transport GO:0009914 121 0.088
purine containing compound metabolic process GO:0072521 253 0.088
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.087
cell projection morphogenesis GO:0048858 123 0.087
regulation of organelle organization GO:0033043 80 0.087
neurotrophin production GO:0032898 2 0.086
stress activated protein kinase signaling cascade GO:0031098 37 0.086
hormone secretion GO:0046879 115 0.086
cell projection organization GO:0030030 302 0.086
positive regulation of multicellular organismal process GO:0051240 387 0.084
establishment of protein localization GO:0045184 141 0.083
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.083
regulation of cell proliferation GO:0042127 359 0.081
sexual reproduction GO:0019953 148 0.081
macromolecular complex assembly GO:0065003 273 0.080
ribose phosphate metabolic process GO:0019693 235 0.080
cellular response to hormone stimulus GO:0032870 247 0.078
reproduction GO:0000003 245 0.078
purine nucleotide metabolic process GO:0006163 229 0.077
cell cycle GO:0007049 101 0.076
locomotory behavior GO:0007626 15 0.076
regulation of endocytosis GO:0030100 42 0.074
response to inorganic substance GO:0010035 377 0.074
negative regulation of cell death GO:0060548 229 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.073
intracellular transport GO:0046907 185 0.072
nucleotide metabolic process GO:0009117 279 0.072
response to monosaccharide GO:0034284 159 0.072
regulation of lipid biosynthetic process GO:0046890 38 0.071
regulation of ion transmembrane transport GO:0034765 121 0.071
negative regulation of response to stimulus GO:0048585 155 0.070
aging GO:0007568 241 0.070
reproductive process GO:0022414 372 0.070
sensory perception GO:0007600 101 0.069
positive regulation of ion transport GO:0043270 94 0.069
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.069
synaptic transmission GO:0007268 235 0.069
protein complex subunit organization GO:0071822 302 0.068
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.068
negative regulation of signaling GO:0023057 157 0.068
regulation of cellular localization GO:0060341 263 0.067
positive regulation of molecular function GO:0044093 230 0.067
membrane organization GO:0061024 94 0.067
locomotory exploration behavior GO:0035641 1 0.066
positive regulation of peptide secretion GO:0002793 52 0.066
regulation of protein transport GO:0051223 68 0.066
intracellular protein transport GO:0006886 79 0.066
tissue development GO:0009888 252 0.065
protein phosphorylation GO:0006468 345 0.065
positive regulation of nervous system development GO:0051962 178 0.065
nitrogen compound transport GO:0071705 229 0.065
negative regulation of signal transduction GO:0009968 83 0.065
locomotion GO:0040011 237 0.064
regulation of apoptotic process GO:0042981 335 0.063
positive regulation of cell migration GO:0030335 96 0.063
purine nucleotide biosynthetic process GO:0006164 83 0.063
positive regulation of rna biosynthetic process GO:1902680 197 0.062
regulation of tube size GO:0035150 89 0.062
negative regulation of programmed cell death GO:0043069 183 0.062
circadian rhythm GO:0007623 88 0.061
regulation of cellular component biogenesis GO:0044087 86 0.060
regulation of cellular protein metabolic process GO:0032268 267 0.060
purine ribonucleotide metabolic process GO:0009150 227 0.060
respiratory system process GO:0003016 3 0.060
anion transport GO:0006820 178 0.059
anatomical structure morphogenesis GO:0009653 298 0.059
protein complex biogenesis GO:0070271 263 0.059
inorganic ion transmembrane transport GO:0098660 229 0.059
positive regulation of phosphate metabolic process GO:0045937 262 0.058
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.058
negative regulation of circadian sleep wake cycle sleep GO:0042321 5 0.058
negative regulation of nucleic acid templated transcription GO:1903507 117 0.058
synaptic transmission gabaergic GO:0051932 22 0.057
positive regulation of peptide hormone secretion GO:0090277 50 0.057
regulation of neuron death GO:1901214 115 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.057
muscle contraction GO:0006936 88 0.057
positive regulation of gene expression GO:0010628 244 0.057
negative regulation of vascular permeability GO:0043116 3 0.056
positive regulation of locomotion GO:0040017 102 0.056
negative regulation of multicellular organismal process GO:0051241 203 0.056
organonitrogen compound biosynthetic process GO:1901566 167 0.056
sensory organ development GO:0007423 74 0.055
pancreatic a cell differentiation GO:0003310 1 0.055
sequestering of metal ion GO:0051238 9 0.055
single organism cellular localization GO:1902580 102 0.054
positive regulation of cell development GO:0010720 176 0.054
growth GO:0040007 165 0.054
cellular response to external stimulus GO:0071496 118 0.054
circulatory system development GO:0072359 134 0.054
monoamine transport GO:0015844 43 0.054
sequestering of calcium ion GO:0051208 8 0.053
negative regulation of gene expression GO:0010629 199 0.053
negative regulation of homeostatic process GO:0032845 47 0.053
regulation of respiratory system process GO:0044065 1 0.053
cytoskeleton organization GO:0007010 111 0.053
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.053
positive regulation of cellular biosynthetic process GO:0031328 295 0.052
negative regulation of rna biosynthetic process GO:1902679 118 0.052
regulation of cardiac muscle contraction GO:0055117 17 0.052
positive regulation of phosphorus metabolic process GO:0010562 262 0.052
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.052
camp metabolic process GO:0046058 63 0.051
multi organism reproductive process GO:0044703 262 0.051
cellular macromolecule localization GO:0070727 122 0.051
regulation of cellular ketone metabolic process GO:0010565 27 0.051
amide transport GO:0042886 105 0.051
synaptic transmission glutamatergic GO:0035249 33 0.051
response to mineralocorticoid GO:0051385 49 0.050
programmed cell death GO:0012501 392 0.050
regulation of actin filament based movement GO:1903115 12 0.050
ribonucleotide metabolic process GO:0009259 231 0.050
receptor metabolic process GO:0043112 18 0.050
epithelial cell differentiation GO:0030855 71 0.049
synaptic growth at neuromuscular junction GO:0051124 1 0.049
potassium ion transport GO:0006813 97 0.048
nucleoside phosphate biosynthetic process GO:1901293 102 0.048
actin mediated cell contraction GO:0070252 12 0.048
response to extracellular stimulus GO:0009991 380 0.048
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.048
second messenger mediated signaling GO:0019932 51 0.048
response to starvation GO:0042594 59 0.048
Rat
regulation of hormone secretion GO:0046883 106 0.048
positive regulation of nucleic acid templated transcription GO:1903508 197 0.048
regulation of cell development GO:0060284 263 0.047
maintenance of location GO:0051235 17 0.047
positive regulation of cell death GO:0010942 184 0.047
leukocyte activation involved in immune response GO:0002366 16 0.047
protein heterooligomerization GO:0051291 89 0.047
myeloid leukocyte differentiation GO:0002573 20 0.047
membrane repolarization GO:0086009 1 0.046
cellular response to organic cyclic compound GO:0071407 202 0.046
response to fatty acid GO:0070542 65 0.046
regulation of cell differentiation GO:0045595 320 0.046
regulation of cellular component movement GO:0051270 150 0.046
positive regulation of developmental process GO:0051094 283 0.045
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.045
single organism reproductive process GO:0044702 297 0.045
single organism organelle organization GO:1902589 180 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.045
positive regulation of secretion GO:0051047 140 0.045
cardiac chamber development GO:0003205 1 0.045
regulation of nervous system development GO:0051960 264 0.045
regulation of potassium ion transport GO:0043266 29 0.045
cyclic nucleotide metabolic process GO:0009187 80 0.044
single organism carbohydrate metabolic process GO:0044723 118 0.044
cellular response to endogenous stimulus GO:0071495 377 0.044
cyclic purine nucleotide metabolic process GO:0052652 62 0.043
startle response GO:0001964 2 0.043
positive regulation of rna metabolic process GO:0051254 203 0.043
steroid metabolic process GO:0008202 73 0.043
developmental process involved in reproduction GO:0003006 159 0.042
purine containing compound biosynthetic process GO:0072522 85 0.042
positive regulation of nucleotide metabolic process GO:0045981 91 0.042
actin filament based movement GO:0030048 16 0.042
positive regulation of endocytosis GO:0045807 28 0.042
cellular protein localization GO:0034613 122 0.041
apoptotic process GO:0006915 381 0.041
myeloid leukocyte mediated immunity GO:0002444 12 0.041
regulation of amine transport GO:0051952 54 0.041
response to estradiol GO:0032355 164 0.040
adult locomotory behavior GO:0008344 4 0.040
negative regulation of cell communication GO:0010648 158 0.040
positive regulation of exocytosis GO:0045921 19 0.040
response to mechanical stimulus GO:0009612 134 0.040
cellular response to abiotic stimulus GO:0071214 85 0.040
melanocyte differentiation GO:0030318 2 0.039
response to camp GO:0051591 91 0.039
Rat
g protein coupled purinergic receptor signaling pathway GO:0035588 8 0.039
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.039
regulation of camp biosynthetic process GO:0030817 38 0.039
taxis GO:0042330 67 0.039
regulation of transporter activity GO:0032409 50 0.039
regulation of kinase activity GO:0043549 117 0.038
steroid biosynthetic process GO:0006694 48 0.038
response to cytokine GO:0034097 215 0.038
regulation of protein metabolic process GO:0051246 289 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.038
detection of external stimulus GO:0009581 13 0.037
axis specification GO:0009798 4 0.037
positive regulation of phagocytosis engulfment GO:0060100 4 0.037
smooth muscle contraction GO:0006939 37 0.037
regulation of phosphate metabolic process GO:0019220 349 0.036
visual perception GO:0007601 3 0.036
regulation of response to stress GO:0080134 126 0.036
organophosphate metabolic process GO:0019637 370 0.036
regulation of homeostatic process GO:0032844 101 0.036
sensory perception of light stimulus GO:0050953 3 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
carbohydrate metabolic process GO:0005975 130 0.035
regulation of camp metabolic process GO:0030814 43 0.035
catecholamine secretion GO:0050432 33 0.035
organelle localization GO:0051640 55 0.035
regulation of transmembrane transport GO:0034762 122 0.035
leukocyte degranulation GO:0043299 12 0.035
neuron apoptotic process GO:0051402 88 0.035
cell growth GO:0016049 104 0.034
regulation of striated muscle contraction GO:0006942 21 0.034
carboxylic acid transport GO:0046942 115 0.034
tissue morphogenesis GO:0048729 22 0.034
nucleotide biosynthetic process GO:0009165 98 0.034
response to nicotine GO:0035094 51 0.034
cell communication involved in cardiac conduction GO:0086065 2 0.033
regulation of synaptic vesicle endocytosis GO:1900242 1 0.033
cellular lipid metabolic process GO:0044255 208 0.033
regulation of amino acid transport GO:0051955 25 0.033
positive regulation of synaptic transmission gabaergic GO:0032230 9 0.033
development of primary female sexual characteristics GO:0046545 56 0.033
oxoacid metabolic process GO:0043436 290 0.033
vasodilation GO:0042311 44 0.033
single organism catabolic process GO:0044712 283 0.033
carbohydrate derivative biosynthetic process GO:1901137 124 0.033
sodium ion homeostasis GO:0055078 23 0.032
catecholamine transport GO:0051937 37 0.032
regulation of actin filament based process GO:0032970 42 0.032
regulation of synaptic transmission GO:0050804 141 0.032
eye development GO:0001654 50 0.032
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.032
multicellular organismal response to stress GO:0033555 25 0.032
response to histamine GO:0034776 3 0.032
regulation of membrane potential GO:0042391 110 0.032
response to hydrogen peroxide GO:0042542 89 0.032
calcium ion transmembrane transport GO:0070588 70 0.032
positive regulation of leukocyte degranulation GO:0043302 4 0.032
cellular response to growth factor stimulus GO:0071363 162 0.031
positive regulation of hormone secretion GO:0046887 65 0.031
regulation of excretion GO:0044062 21 0.031
positive regulation of adenylate cyclase activity GO:0045762 12 0.031
calcium ion transport into cytosol GO:0060402 38 0.030
catabolic process GO:0009056 351 0.030
calcium mediated signaling GO:0019722 23 0.030
protein tetramerization GO:0051262 38 0.030
regulation of hormone levels GO:0010817 187 0.030
organic hydroxy compound transport GO:0015850 77 0.030
release of sequestered calcium ion into cytosol GO:0051209 25 0.030
negative regulation of phosphorus metabolic process GO:0010563 80 0.030
regulation of intracellular transport GO:0032386 65 0.030
positive regulation of synaptic vesicle recycling GO:1903423 1 0.029
camp biosynthetic process GO:0006171 47 0.029
positive regulation of synaptic vesicle endocytosis GO:1900244 1 0.029
negative regulation of neuron apoptotic process GO:0043524 45 0.029
negative regulation of protein phosphorylation GO:0001933 44 0.029
embryonic pattern specification GO:0009880 1 0.029
regulation of receptor activity GO:0010469 29 0.029
phenol containing compound metabolic process GO:0018958 30 0.029
cellular catabolic process GO:0044248 295 0.028
positive regulation of calcium ion transport GO:0051928 36 0.028
negative regulation of amine transport GO:0051953 24 0.028
positive regulation of cellular component movement GO:0051272 102 0.028
behavioral response to ethanol GO:0048149 1 0.028
hormone metabolic process GO:0042445 69 0.028
regulation of protein localization GO:0032880 81 0.028
ribose phosphate biosynthetic process GO:0046390 87 0.028
chemosensory behavior GO:0007635 2 0.028
amine transport GO:0015837 57 0.028
cardiac muscle cell contraction GO:0086003 10 0.028
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.028
muscle cell proliferation GO:0033002 84 0.028
oxidation reduction process GO:0055114 304 0.028
cell activation involved in immune response GO:0002263 16 0.027
smooth muscle cell proliferation GO:0048659 77 0.027
positive regulation of neurotransmitter secretion GO:0001956 9 0.027
regulation of nucleotide metabolic process GO:0006140 117 0.027
regulation of vascular smooth muscle contraction GO:0003056 3 0.027
gamete generation GO:0007276 124 0.027
cardiovascular system development GO:0072358 134 0.027
rhythmic synaptic transmission GO:0060024 1 0.027
autonomic nervous system development GO:0048483 3 0.027
cellular response to ketone GO:1901655 51 0.027
axonogenesis GO:0007409 71 0.026
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
cell cycle process GO:0022402 57 0.026
cerebellar cortex formation GO:0021697 2 0.026
response to acid chemical GO:0001101 222 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
axon development GO:0061564 96 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
peptide transport GO:0015833 97 0.025
peptide secretion GO:0002790 86 0.025
organic substance catabolic process GO:1901575 316 0.025
negative regulation of cell proliferation GO:0008285 119 0.025
regulation of protein serine threonine kinase activity GO:0071900 64 0.025
regulation of phagocytosis engulfment GO:0060099 4 0.025
regulation of lipid metabolic process GO:0019216 68 0.025
response to calcium ion GO:0051592 59 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.025
regulation of renal sodium excretion GO:0035813 20 0.025
protein secretion GO:0009306 34 0.025
cardiac ventricle development GO:0003231 1 0.025
negative regulation of phosphate metabolic process GO:0045936 80 0.024
positive regulation of leukocyte mediated immunity GO:0002705 13 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
purinergic receptor signaling pathway GO:0035587 10 0.024
olfactory behavior GO:0042048 2 0.024
adult behavior GO:0030534 16 0.024
ribonucleotide biosynthetic process GO:0009260 85 0.024
cell motility GO:0048870 202 0.024
presynaptic membrane assembly GO:0097105 3 0.024
negative regulation of epinephrine secretion GO:0032811 6 0.024
catecholamine biosynthetic process GO:0042423 9 0.024
development of primary sexual characteristics GO:0045137 107 0.024
positive regulation of renal sodium excretion GO:0035815 10 0.024
cardiac muscle cell action potential GO:0086001 5 0.024
negative regulation of sequestering of calcium ion GO:0051283 25 0.024
positive regulation of muscle contraction GO:0045933 22 0.023
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.023
regulation of neuron projection development GO:0010975 161 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
mitotic cell cycle process GO:1903047 35 0.023
response to pain GO:0048265 11 0.023
norepinephrine secretion GO:0048243 16 0.023
behavior GO:0007610 205 0.023
immune response GO:0006955 104 0.023
positive regulation of neural precursor cell proliferation GO:2000179 10 0.023
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
positive regulation of insulin secretion GO:0032024 36 0.022
glutamate secretion GO:0014047 19 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
response to manganese ion GO:0010042 13 0.022
response to metal ion GO:0010038 253 0.022
regulation of respiratory gaseous exchange GO:0043576 2 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
negative regulation of collagen biosynthetic process GO:0032966 4 0.022
locomotor rhythm GO:0045475 1 0.022
positive regulation of camp mediated signaling GO:0043950 2 0.022

Pfkfb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.131
nervous system disease DOID:863 0 0.131
cardiovascular system disease DOID:1287 0 0.066
central nervous system disease DOID:331 0 0.043
sensory system disease DOID:0050155 0 0.041
eye and adnexa disease DOID:1492 0 0.041
eye disease DOID:5614 0 0.041
long qt syndrome DOID:2843 0 0.028
disease of metabolism DOID:0014667 0 0.027
inherited metabolic disorder DOID:655 0 0.027
brain disease DOID:936 0 0.025