Rattus norvegicus

23 known processes

Pfkfb3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Pfkfb3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.657
response to hypoxia GO:0001666 231 0.553
response to glucocorticoid GO:0051384 223 0.549
Rat
apoptotic process GO:0006915 381 0.398
response to oxygen levels GO:0070482 265 0.372
organophosphate metabolic process GO:0019637 370 0.345
response to corticosteroid GO:0031960 235 0.342
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.341
nucleic acid templated transcription GO:0097659 379 0.304
rna biosynthetic process GO:0032774 380 0.297
regulation of rna biosynthetic process GO:2001141 381 0.287
negative regulation of cellular metabolic process GO:0031324 281 0.267
tissue development GO:0009888 252 0.248
regulation of rna metabolic process GO:0051252 391 0.247
response to cytokine GO:0034097 215 0.239
regulation of transcription dna templated GO:0006355 374 0.227
rna metabolic process GO:0016070 406 0.214
positive regulation of rna metabolic process GO:0051254 203 0.209
programmed cell death GO:0012501 392 0.202
cellular response to cytokine stimulus GO:0071345 127 0.198
response to peptide hormone GO:0043434 278 0.193
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.190
negative regulation of gene expression GO:0010629 199 0.188
response to peptide GO:1901652 292 0.175
Rat
regulation of cellular localization GO:0060341 263 0.174
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.173
response to carbohydrate GO:0009743 183 0.173
Rat
regulation of transmembrane transport GO:0034762 122 0.167
negative regulation of cellular component organization GO:0051129 83 0.165
negative regulation of programmed cell death GO:0043069 183 0.165
cellular response to endogenous stimulus GO:0071495 377 0.165
organic acid metabolic process GO:0006082 292 0.162
Rat
regulation of cell proliferation GO:0042127 359 0.156
enzyme linked receptor protein signaling pathway GO:0007167 116 0.155
cellular response to hormone stimulus GO:0032870 247 0.153
positive regulation of cellular biosynthetic process GO:0031328 295 0.143
transcription from rna polymerase ii promoter GO:0006366 252 0.138
negative regulation of metabolic process GO:0009892 331 0.135
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.135
carboxylic acid metabolic process GO:0019752 289 0.131
Rat
response to decreased oxygen levels GO:0036293 237 0.127
cell type specific apoptotic process GO:0097285 134 0.126
response to nutrient levels GO:0031667 370 0.122
Rat
regulation of molecular function GO:0065009 398 0.119
Rat
epithelium development GO:0060429 96 0.116
regulation of intracellular signal transduction GO:1902531 218 0.116
response to extracellular stimulus GO:0009991 380 0.115
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.113
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.112
cellular response to peptide GO:1901653 133 0.111
vesicle mediated transport GO:0016192 181 0.110
negative regulation of signaling GO:0023057 157 0.108
single organism intracellular transport GO:1902582 166 0.104
intracellular signal transduction GO:0035556 314 0.100
response to molecule of bacterial origin GO:0002237 194 0.099
negative regulation of cell communication GO:0010648 158 0.098
positive regulation of biosynthetic process GO:0009891 319 0.096
sex differentiation GO:0007548 113 0.096
immune system process GO:0002376 204 0.095
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.095
cellular response to oxygen containing compound GO:1901701 386 0.094
regulation of secretion by cell GO:1903530 208 0.093
Rat
regulation of system process GO:0044057 208 0.091
transcription dna templated GO:0006351 377 0.090
response to other organism GO:0051707 220 0.088
response to insulin GO:0032868 133 0.088
Rat
positive regulation of cell death GO:0010942 184 0.086
cell projection organization GO:0030030 302 0.085
positive regulation of rna biosynthetic process GO:1902680 197 0.084
cellular response to organonitrogen compound GO:0071417 197 0.083
regulation of hormone secretion GO:0046883 106 0.080
Rat
regulation of nervous system development GO:0051960 264 0.080
secretion by cell GO:0032940 248 0.079
Rat
cell migration GO:0016477 197 0.079
positive regulation of apoptotic process GO:0043065 154 0.077
regulation of peptide transport GO:0090087 87 0.076
Rat
lipid metabolic process GO:0006629 283 0.076
response to purine containing compound GO:0014074 126 0.076
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.073
purine nucleotide metabolic process GO:0006163 229 0.072
regulation of phosphorus metabolic process GO:0051174 349 0.072
Rat
positive regulation of cell proliferation GO:0008284 249 0.072
response to acid chemical GO:0001101 222 0.070
reproductive structure development GO:0048608 128 0.070
protein phosphorylation GO:0006468 345 0.068
regulation of cellular component organization GO:0051128 368 0.066
brain development GO:0007420 247 0.066
negative regulation of cellular biosynthetic process GO:0031327 161 0.065
regulation of phosphate metabolic process GO:0019220 349 0.064
Rat
peptide transport GO:0015833 97 0.064
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.063
response to amine GO:0014075 46 0.062
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.062
secretion GO:0046903 307 0.061
Rat
immune response GO:0006955 104 0.061
cellular amino acid metabolic process GO:0006520 107 0.061
divalent metal ion transport GO:0070838 132 0.061
development of primary female sexual characteristics GO:0046545 56 0.061
mapk cascade GO:0000165 140 0.060
cellular amine metabolic process GO:0044106 38 0.060
response to bacterium GO:0009617 200 0.059
regulation of catalytic activity GO:0050790 304 0.059
Rat
metal ion transport GO:0030001 289 0.059
response to growth factor GO:0070848 189 0.059
regulation of signal transduction GO:0009966 318 0.058
regulation of apoptotic process GO:0042981 335 0.058
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.058
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.057
hormone transport GO:0009914 121 0.057
Rat
positive regulation of gene expression GO:0010628 244 0.057
regeneration GO:0031099 163 0.057
Rat
amine metabolic process GO:0009308 38 0.056
regulation of follicle stimulating hormone secretion GO:0046880 5 0.055
response to external biotic stimulus GO:0043207 221 0.055
gliogenesis GO:0042063 93 0.055
negative regulation of biosynthetic process GO:0009890 168 0.055
cation transport GO:0006812 382 0.055
single organism reproductive process GO:0044702 297 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.054
cellular chemical homeostasis GO:0055082 247 0.054
carbohydrate derivative metabolic process GO:1901135 346 0.054
localization of cell GO:0051674 202 0.053
response to metal ion GO:0010038 253 0.052
regulation of cell development GO:0060284 263 0.052
positive regulation of nervous system development GO:0051962 178 0.052
carbohydrate derivative biosynthetic process GO:1901137 124 0.051
response to monosaccharide GO:0034284 159 0.051
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.051
proteolysis GO:0006508 175 0.050
regulation of cellular amino acid metabolic process GO:0006521 2 0.050
defense response GO:0006952 194 0.050
cellular response to insulin stimulus GO:0032869 81 0.050
positive regulation of brown fat cell proliferation GO:0070349 1 0.050
response to hexose GO:0009746 144 0.050
Rat
cellular response to growth factor stimulus GO:0071363 162 0.049
regulation of synaptic transmission GO:0050804 141 0.048
negative regulation of response to stimulus GO:0048585 155 0.047
neuron development GO:0048666 286 0.047
negative regulation of molecular function GO:0044092 133 0.047
negative regulation of rna metabolic process GO:0051253 123 0.046
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.046
oxoacid metabolic process GO:0043436 290 0.046
Rat
cellular ketone metabolic process GO:0042180 51 0.046
response to tumor necrosis factor GO:0034612 56 0.046
cellular homeostasis GO:0019725 252 0.046
response to biotic stimulus GO:0009607 226 0.046
establishment of protein localization GO:0045184 141 0.045
regulation of multicellular organismal development GO:2000026 376 0.045
negative regulation of cell death GO:0060548 229 0.045
signal transduction by phosphorylation GO:0023014 144 0.044
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.044
cellular response to peptide hormone stimulus GO:0071375 120 0.044
transforming growth factor beta3 production GO:0032907 2 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.043
small molecule biosynthetic process GO:0044283 124 0.043
regulation of response to stress GO:0080134 126 0.043
negative regulation of protein metabolic process GO:0051248 114 0.043
lens fiber cell differentiation GO:0070306 3 0.043
response to inorganic substance GO:0010035 377 0.042
regulation of ion transport GO:0043269 245 0.042
cell motility GO:0048870 202 0.042
single organism biosynthetic process GO:0044711 342 0.042
protein processing GO:0016485 68 0.041
negative regulation of rna biosynthetic process GO:1902679 118 0.041
cell growth GO:0016049 104 0.041
negative regulation of apoptotic process GO:0043066 181 0.041
positive regulation of cell differentiation GO:0045597 217 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
regulation of response to external stimulus GO:0032101 106 0.040
carbohydrate metabolic process GO:0005975 130 0.040
Yeast Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.040
negative regulation of nucleic acid templated transcription GO:1903507 117 0.040
cytokine mediated signaling pathway GO:0019221 43 0.039
cellular response to molecule of bacterial origin GO:0071219 56 0.039
coronary vasculature morphogenesis GO:0060977 3 0.039
cellular response to stress GO:0033554 269 0.039
cellular metal ion homeostasis GO:0006875 172 0.039
cell cell signaling GO:0007267 335 0.039
Rat
regulation of homeostatic process GO:0032844 101 0.039
cellular response to organic cyclic compound GO:0071407 202 0.038
positive regulation of developmental process GO:0051094 283 0.038
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.038
organophosphate biosynthetic process GO:0090407 143 0.037
alcohol metabolic process GO:0006066 77 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.037
regulation of protein metabolic process GO:0051246 289 0.037
leukocyte activation GO:0045321 76 0.037
cellular response to external stimulus GO:0071496 118 0.036
regulation of hydrolase activity GO:0051336 143 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.036
regulation of peptide secretion GO:0002791 82 0.036
Rat
positive regulation of transcription dna templated GO:0045893 197 0.035
regulation of protein modification process GO:0031399 194 0.035
protein localization GO:0008104 191 0.035
cellular macromolecule localization GO:0070727 122 0.035
positive regulation of signaling GO:0023056 270 0.035
Rat
epithelial cell differentiation GO:0030855 71 0.035
dna metabolic process GO:0006259 96 0.035
regulation of phosphorylation GO:0042325 248 0.035
Rat
regulation of metal ion transport GO:0010959 118 0.035
positive regulation of molecular function GO:0044093 230 0.035
Rat
calcium ion transport GO:0006816 131 0.035
intracellular transport GO:0046907 185 0.035
nitrogen compound transport GO:0071705 229 0.034
Rat
nucleotide metabolic process GO:0009117 279 0.034
regulation of ion transmembrane transport GO:0034765 121 0.034
regulation of calcium ion transport GO:0051924 77 0.034
response to radiation GO:0009314 137 0.034
carbohydrate homeostasis GO:0033500 75 0.033
positive regulation of cell communication GO:0010647 271 0.033
Rat
cell activation GO:0001775 97 0.033
negative regulation of secretion by cell GO:1903531 72 0.032
divalent inorganic cation transport GO:0072511 134 0.032
aging GO:0007568 241 0.032
response to wounding GO:0009611 254 0.032
positive regulation of programmed cell death GO:0043068 157 0.031
negative regulation of protein phosphorylation GO:0001933 44 0.031
cellular response to glucocorticoid stimulus GO:0071385 68 0.031
reproduction GO:0000003 245 0.031
membrane organization GO:0061024 94 0.031
cellular divalent inorganic cation homeostasis GO:0072503 162 0.031
protein maturation GO:0051604 68 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
response to fungicide GO:0060992 20 0.031
cellular protein localization GO:0034613 122 0.030
response to oxidative stress GO:0006979 186 0.030
nucleotide biosynthetic process GO:0009165 98 0.030
cellular lipid metabolic process GO:0044255 208 0.030
cellular response to corticosteroid stimulus GO:0071384 69 0.030
phosphatidylcholine biosynthetic process GO:0006656 5 0.029
circulatory system process GO:0003013 183 0.029
intracellular protein transport GO:0006886 79 0.029
negative regulation of secretion GO:0051048 82 0.029
regulation of cell differentiation GO:0045595 320 0.029
response to magnesium ion GO:0032026 20 0.028
purine containing compound metabolic process GO:0072521 253 0.028
signal release GO:0023061 145 0.028
Rat
sexual reproduction GO:0019953 148 0.028
positive regulation of catalytic activity GO:0043085 184 0.028
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 10 0.028
cellular response to metal ion GO:0071248 55 0.028
developmental process involved in reproduction GO:0003006 159 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
negative regulation of transport GO:0051051 136 0.028
regulation of secretion GO:0051046 224 0.028
Rat
single organism organelle organization GO:1902589 180 0.028
response to nutrient GO:0007584 248 0.027
positive regulation of transport GO:0051050 245 0.027
Rat
negative regulation of developmental process GO:0051093 125 0.027
alcohol biosynthetic process GO:0046165 38 0.027
immune effector process GO:0002252 53 0.027
cellular component movement GO:0006928 248 0.027
negative regulation of catalytic activity GO:0043086 103 0.027
regulation of neuron projection development GO:0010975 161 0.027
regulation of catabolic process GO:0009894 113 0.027
male sex differentiation GO:0046661 64 0.026
response to glucose GO:0009749 136 0.026
Rat
regulation of insulin secretion GO:0050796 65 0.026
Rat
skeletal system development GO:0001501 41 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
Rat
response to amphetamine GO:0001975 25 0.026
response to ketone GO:1901654 182 0.025
morphogenesis of an epithelium GO:0002009 20 0.025
positive regulation of cell projection organization GO:0031346 111 0.025
regulation of mapk cascade GO:0043408 116 0.025
single organism catabolic process GO:0044712 283 0.024
Rat
regulation of body fluid levels GO:0050878 90 0.024
insulin secretion GO:0030073 69 0.024
Rat
head development GO:0060322 247 0.024
chromosome segregation GO:0007059 2 0.024
cellular response to nutrient levels GO:0031669 60 0.024
amide transport GO:0042886 105 0.023
Rat
ion transmembrane transport GO:0034220 365 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.023
positive regulation of fat cell proliferation GO:0070346 1 0.023
reactive oxygen species metabolic process GO:0072593 37 0.023
homeostatic process GO:0042592 331 0.023
regulation of hormone levels GO:0010817 187 0.023
Rat
female sex differentiation GO:0046660 59 0.022
reproductive process GO:0022414 372 0.022
ion homeostasis GO:0050801 212 0.022
negative regulation of signal transduction GO:0009968 83 0.022
ras protein signal transduction GO:0007265 29 0.022
cellular response to lipid GO:0071396 201 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
Rat
regulation of neurogenesis GO:0050767 247 0.022
cell cycle GO:0007049 101 0.022
positive regulation of locomotion GO:0040017 102 0.022
neuron differentiation GO:0030182 368 0.022
regulation of purine nucleotide metabolic process GO:1900542 115 0.022
development of primary sexual characteristics GO:0045137 107 0.022
organ regeneration GO:0031100 101 0.022
Rat
response to transforming growth factor beta GO:0071559 46 0.022
cellular cation homeostasis GO:0030003 180 0.022
response to estrogen GO:0043627 232 0.022
organic anion transport GO:0015711 132 0.021
heart morphogenesis GO:0003007 3 0.021
sleep GO:0030431 30 0.021
positive regulation of peptide secretion GO:0002793 52 0.021
Rat
organophosphate catabolic process GO:0046434 148 0.021
regulation of cell motility GO:2000145 131 0.021
negative regulation of response to external stimulus GO:0032102 37 0.021
bmp signaling pathway GO:0030509 4 0.020
male gonad development GO:0008584 59 0.020
regulation of dna metabolic process GO:0051052 60 0.020
regulation of response to wounding GO:1903034 69 0.020
neuron projection development GO:0031175 273 0.020
dephosphorylation GO:0016311 98 0.020
Yeast Rat
calcium ion import GO:0070509 22 0.020
organic substance catabolic process GO:1901575 316 0.020
Rat
response to alkaloid GO:0043279 132 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
response to dexamethasone GO:0071548 49 0.020
peptide hormone secretion GO:0030072 84 0.020
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
endocytosis GO:0006897 84 0.020
cellular ion homeostasis GO:0006873 184 0.020
ribose phosphate biosynthetic process GO:0046390 87 0.020
mitochondrion organization GO:0007005 35 0.020
salivary gland development GO:0007431 3 0.019
response to estradiol GO:0032355 164 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
regulation of neuron differentiation GO:0045664 208 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
second messenger mediated signaling GO:0019932 51 0.019
negative regulation of response to wounding GO:1903035 23 0.019
multi organism reproductive process GO:0044703 262 0.019
response to fatty acid GO:0070542 65 0.019
bone development GO:0060348 25 0.019
cellular carbohydrate metabolic process GO:0044262 72 0.019
Yeast Rat
cellular calcium ion homeostasis GO:0006874 160 0.019
reproductive system development GO:0061458 128 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
cellular response to lipopolysaccharide GO:0071222 55 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.018
chemical homeostasis GO:0048878 292 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
response to hyperoxia GO:0055093 45 0.018
response to vitamin GO:0033273 131 0.018
metal ion homeostasis GO:0055065 186 0.018
gland development GO:0048732 155 0.018
locomotion GO:0040011 237 0.018
hexose transport GO:0008645 29 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
cellular response to inorganic substance GO:0071241 65 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
regulation of protein catabolic process GO:0042176 16 0.018
gamete generation GO:0007276 124 0.018
inflammatory response GO:0006954 150 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
camp metabolic process GO:0046058 63 0.017
regulation of ion homeostasis GO:2000021 63 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
central nervous system development GO:0007417 311 0.017
regulation of cellular response to growth factor stimulus GO:0090287 15 0.017
cellular component morphogenesis GO:0032989 155 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
response to interleukin 1 GO:0070555 55 0.017
receptor mediated endocytosis GO:0006898 42 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
cyclic nucleotide biosynthetic process GO:0009190 63 0.017
mitotic spindle organization GO:0007052 2 0.017
pro t cell differentiation GO:0002572 1 0.017
developmental growth GO:0048589 100 0.017
cation homeostasis GO:0055080 195 0.017
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.016
b cell differentiation GO:0030183 2 0.016
response to hydrogen peroxide GO:0042542 89 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.016
positive regulation of ion transport GO:0043270 94 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.016
catabolic process GO:0009056 351 0.016
Rat
purine nucleotide catabolic process GO:0006195 136 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
salivary gland morphogenesis GO:0007435 1 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
Rat
cell cycle checkpoint GO:0000075 2 0.016
regulation of immunoglobulin production GO:0002637 4 0.016
response to organophosphorus GO:0046683 102 0.016
Rat
response to reactive oxygen species GO:0000302 120 0.016
cellular macromolecular complex assembly GO:0034622 58 0.016
regulation of peptidase activity GO:0052547 55 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.015
regulation of b cell differentiation GO:0045577 1 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
regulation of cation channel activity GO:2001257 23 0.015
l glutamate import GO:0051938 2 0.015
blood vessel development GO:0001568 69 0.015
response to calcium ion GO:0051592 59 0.015
lipid biosynthetic process GO:0008610 128 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
regulation of proteolysis GO:0030162 66 0.015
actin filament based process GO:0030029 86 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
lens development in camera type eye GO:0002088 13 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
regulation of transporter activity GO:0032409 50 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
Rat
regulation of neuron death GO:1901214 115 0.015
response to activity GO:0014823 73 0.015
protein transport GO:0015031 132 0.015
cell migration involved in metanephros development GO:0035788 2 0.015
transmembrane transport GO:0055085 412 0.015
cellular response to tumor necrosis factor GO:0071356 46 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
purine containing compound biosynthetic process GO:0072522 85 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.014
chemotaxis GO:0006935 66 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
female pregnancy GO:0007565 122 0.014
positive regulation of transmembrane transport GO:0034764 25 0.014
macromolecule localization GO:0033036 252 0.014
negative regulation of homeostatic process GO:0032845 47 0.014
renal system development GO:0072001 67 0.014
receptor metabolic process GO:0043112 18 0.014
negative regulation of peptide hormone secretion GO:0090278 30 0.014
positive regulation of signal transduction GO:0009967 175 0.014
cytoplasmic transport GO:0016482 115 0.014
lymphocyte activation GO:0046649 43 0.014
glucose homeostasis GO:0042593 75 0.014
regulation of transmembrane transporter activity GO:0022898 49 0.014
positive regulation of calcium ion transport GO:0051928 36 0.014
carbohydrate biosynthetic process GO:0016051 42 0.014
negative regulation of skeletal muscle tissue development GO:0048642 3 0.014
mesonephros development GO:0001823 14 0.014
multicellular organismal homeostasis GO:0048871 49 0.013
response to retinoic acid GO:0032526 63 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
smooth muscle cell migration GO:0014909 36 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
regulation of dendrite development GO:0050773 59 0.013
erythrocyte differentiation GO:0030218 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
protein complex assembly GO:0006461 263 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
negative adaptation of signaling pathway GO:0022401 10 0.013
regulation of cellular component movement GO:0051270 150 0.013
protein catabolic process GO:0030163 30 0.013
embryonic cranial skeleton morphogenesis GO:0048701 2 0.013
actin cytoskeleton organization GO:0030036 73 0.013
embryonic skeletal system morphogenesis GO:0048704 3 0.013
response to lipopolysaccharide GO:0032496 191 0.013
cell morphogenesis GO:0000902 142 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
regulation of vasculature development GO:1901342 44 0.013
peptide secretion GO:0002790 86 0.013
Rat
formation of primary germ layer GO:0001704 1 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
heterocycle catabolic process GO:0046700 167 0.013
phospholipid metabolic process GO:0006644 61 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
endomembrane system organization GO:0010256 48 0.013
wound healing GO:0042060 122 0.013
b cell activation involved in immune response GO:0002312 1 0.012
sequestering of metal ion GO:0051238 9 0.012
negative regulation of hormone secretion GO:0046888 46 0.012
dendrite development GO:0016358 72 0.012
regulation of locomotion GO:0040012 148 0.012
growth GO:0040007 165 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
regulation of organelle organization GO:0033043 80 0.012
regulation of cell projection organization GO:0031344 175 0.012
negative regulation of vascular permeability GO:0043116 3 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
regulation of protein maturation GO:1903317 50 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.012
regulation of muscle organ development GO:0048634 26 0.012
muscle tissue development GO:0060537 58 0.012
embryonic skeletal system development GO:0048706 3 0.012
response to corticosterone GO:0051412 40 0.012
regulation of leukocyte activation GO:0002694 45 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
male gamete generation GO:0048232 99 0.012
purine containing compound catabolic process GO:0072523 138 0.012
positive regulation of serotonin secretion GO:0014064 1 0.012
muscle structure development GO:0061061 87 0.012
hexose metabolic process GO:0019318 58 0.012
Yeast Rat
positive regulation of cell activation GO:0050867 34 0.012

Pfkfb3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
neuropathy DOID:870 0 0.016
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.012