Rattus norvegicus

42 known processes

Pgcp

plasma glutamate carboxypeptidase

(Aliases: LAL,lal-1)

Pgcp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to glucocorticoid GO:0051384 223 0.316
response to corticosteroid GO:0031960 235 0.274
response to metal ion GO:0010038 253 0.248
response to inorganic substance GO:0010035 377 0.223
response to wounding GO:0009611 254 0.191
regulation of locomotion GO:0040012 148 0.182
ureteric bud development GO:0001657 14 0.136
mesonephros development GO:0001823 14 0.126
response to nutrient levels GO:0031667 370 0.123
regulation of blood coagulation GO:0030193 9 0.114
response to alkaloid GO:0043279 132 0.111
response to external biotic stimulus GO:0043207 221 0.109
cellular amide metabolic process GO:0043603 44 0.106
Human
regulation of response to stress GO:0080134 126 0.104
tissue development GO:0009888 252 0.097
peptidyl glutamic acid modification GO:0018200 1 0.087
response to camp GO:0051591 91 0.083
response to retinoic acid GO:0032526 63 0.077
positive regulation of response to stimulus GO:0048584 285 0.076
response to carbohydrate GO:0009743 183 0.075
response to acid chemical GO:0001101 222 0.074
mesonephric epithelium development GO:0072163 14 0.072
cellular lipid metabolic process GO:0044255 208 0.070
inflammatory response GO:0006954 150 0.066
glial cell differentiation GO:0010001 65 0.063
response to cytokine GO:0034097 215 0.063
peptide metabolic process GO:0006518 32 0.062
Human
regulation of cellular protein metabolic process GO:0032268 267 0.062
oxidation reduction process GO:0055114 304 0.060
aging GO:0007568 241 0.059
secretion by cell GO:0032940 248 0.058
response to other organism GO:0051707 220 0.058
response to biotic stimulus GO:0009607 226 0.057
response to extracellular stimulus GO:0009991 380 0.057
kidney epithelium development GO:0072073 19 0.051
regulation of cell development GO:0060284 263 0.049
cellular catabolic process GO:0044248 295 0.048
Human
mesonephric tubule development GO:0072164 14 0.047
urogenital system development GO:0001655 78 0.046
response to estradiol GO:0032355 164 0.045
negative regulation of cell death GO:0060548 229 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
regulation of neurogenesis GO:0050767 247 0.042
response to lipopolysaccharide GO:0032496 191 0.041
cellular response to endogenous stimulus GO:0071495 377 0.041
cellular response to organic cyclic compound GO:0071407 202 0.039
brain development GO:0007420 247 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
response to bacterium GO:0009617 200 0.038
regulation of coagulation GO:0050818 11 0.038
response to nicotine GO:0035094 51 0.037
response to oxidative stress GO:0006979 186 0.037
single organism catabolic process GO:0044712 283 0.037
organic substance catabolic process GO:1901575 316 0.036
Human
complement activation GO:0006956 11 0.036
single organism reproductive process GO:0044702 297 0.036
regulation of dopamine metabolic process GO:0042053 5 0.036
multi multicellular organism process GO:0044706 138 0.035
growth GO:0040007 165 0.035
behavior GO:0007610 205 0.035
central nervous system development GO:0007417 311 0.035
response to peptide hormone GO:0043434 278 0.035
catabolic process GO:0009056 351 0.034
Human
response to monosaccharide GO:0034284 159 0.034
cellular amine metabolic process GO:0044106 38 0.033
cellular response to steroid hormone stimulus GO:0071383 93 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
secretion GO:0046903 307 0.032
response to vitamin GO:0033273 131 0.032
positive regulation of apoptotic process GO:0043065 154 0.031
response to organophosphorus GO:0046683 102 0.031
cellular response to hormone stimulus GO:0032870 247 0.031
kidney development GO:0001822 67 0.030
epithelium development GO:0060429 96 0.030
response to ethanol GO:0045471 162 0.030
cellular response to lipid GO:0071396 201 0.030
regulation of immune response GO:0050776 55 0.030
cellular response to cytokine stimulus GO:0071345 127 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.029
proteolysis GO:0006508 175 0.029
protein processing GO:0016485 68 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
lipid metabolic process GO:0006629 283 0.029
response to toxic substance GO:0009636 133 0.029
response to ketone GO:1901654 182 0.029
positive regulation of cell death GO:0010942 184 0.029
dopamine metabolic process GO:0042417 12 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
reproductive process GO:0022414 372 0.028
positive regulation of molecular function GO:0044093 230 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
organic acid metabolic process GO:0006082 292 0.027
amine metabolic process GO:0009308 38 0.027
tube development GO:0035295 89 0.027
wound healing GO:0042060 122 0.027
fibrinolysis GO:0042730 2 0.027
response to nutrient GO:0007584 248 0.027
regulation of protein metabolic process GO:0051246 289 0.027
chemical homeostasis GO:0048878 292 0.026
regulation of cell proliferation GO:0042127 359 0.026
lung lobe development GO:0060462 1 0.026
serotonin metabolic process GO:0042428 3 0.025
carbohydrate catabolic process GO:0016052 40 0.025
insulin like growth factor receptor signaling pathway GO:0048009 3 0.025
response to purine containing compound GO:0014074 126 0.025
organophosphate metabolic process GO:0019637 370 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
steroid biosynthetic process GO:0006694 48 0.025
regulation of neuron death GO:1901214 115 0.025
organ morphogenesis GO:0009887 75 0.024
response to radiation GO:0009314 137 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
steroid metabolic process GO:0008202 73 0.024
oxoacid metabolic process GO:0043436 290 0.024
regulation of cell differentiation GO:0045595 320 0.023
cellular response to external stimulus GO:0071496 118 0.023
single organism carbohydrate catabolic process GO:0044724 40 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
nucleotide metabolic process GO:0009117 279 0.022
regulation of catalytic activity GO:0050790 304 0.022
regulation of wound healing GO:0061041 14 0.022
regulation of cell projection organization GO:0031344 175 0.022
regulation of fibrinolysis GO:0051917 2 0.022
response to peptide GO:1901652 292 0.022
regulation of nervous system development GO:0051960 264 0.022
single organism behavior GO:0044708 130 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
cation transport GO:0006812 382 0.022
sulfur compound metabolic process GO:0006790 70 0.022
positive regulation of cell proliferation GO:0008284 249 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.021
single organism biosynthetic process GO:0044711 342 0.020
regulation of neuron projection development GO:0010975 161 0.019
monosaccharide metabolic process GO:0005996 61 0.019
organic acid catabolic process GO:0016054 49 0.019
response to hydrogen peroxide GO:0042542 89 0.019
positive regulation of immune response GO:0050778 42 0.019
response to calcium ion GO:0051592 59 0.019
response to hexose GO:0009746 144 0.019
regeneration GO:0031099 163 0.019
prostate gland epithelium morphogenesis GO:0060740 2 0.019
cellular response to glucocorticoid stimulus GO:0071385 68 0.018
positive regulation of kinase activity GO:0033674 77 0.018
regulation of hemostasis GO:1900046 9 0.018
positive regulation of nervous system development GO:0051962 178 0.018
response to mineralocorticoid GO:0051385 49 0.018
metal ion transport GO:0030001 289 0.018
carboxylic acid catabolic process GO:0046395 49 0.018
hemostasis GO:0007599 26 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.017
defense response GO:0006952 194 0.017
prostate gland morphogenesis GO:0060512 2 0.017
response to herbicide GO:0009635 16 0.017
regulation of ion transport GO:0043269 245 0.017
small molecule catabolic process GO:0044282 59 0.016
cellular modified amino acid metabolic process GO:0006575 61 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
protein phosphorylation GO:0006468 345 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
homeostatic process GO:0042592 331 0.016
response to amino acid GO:0043200 75 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
cartilage development GO:0051216 22 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
Human
regulation of cellular component movement GO:0051270 150 0.016
regulation of cell migration GO:0030334 128 0.016
positive regulation of developmental process GO:0051094 283 0.015
halogenated hydrocarbon metabolic process GO:0042197 4 0.015
positive regulation of hemostasis GO:1900048 4 0.015
jak stat cascade GO:0007259 26 0.015
ameboidal type cell migration GO:0001667 26 0.015
regulation of body fluid levels GO:0050878 90 0.015
carbohydrate metabolic process GO:0005975 130 0.015
locomotion GO:0040011 237 0.015
neuron death GO:0070997 127 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
neuron differentiation GO:0030182 368 0.015
peptidyl amino acid modification GO:0018193 126 0.014
camp metabolic process GO:0046058 63 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
regulation of immune system process GO:0002682 123 0.014
positive regulation of cell junction assembly GO:1901890 2 0.014
positive regulation of immune system process GO:0002684 90 0.014
cell part morphogenesis GO:0032990 123 0.014
positive regulation of locomotion GO:0040017 102 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
regulation of dendrite development GO:0050773 59 0.014
renal system development GO:0072001 67 0.014
regulation of protein kinase activity GO:0045859 105 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of hydrolase activity GO:0051336 143 0.014
secondary metabolic process GO:0019748 15 0.014
negative regulation of response to external stimulus GO:0032102 37 0.014
response to fluoride GO:1902617 3 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
regulation of growth GO:0040008 105 0.013
cellular polysaccharide metabolic process GO:0044264 23 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
cellular ketone metabolic process GO:0042180 51 0.013
response to estrogen GO:0043627 232 0.013
cell proliferation in external granule layer GO:0021924 1 0.013
response to glucose GO:0009749 136 0.013
positive regulation of signaling GO:0023056 270 0.013
protein maturation GO:0051604 68 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of cell motility GO:2000145 131 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
positive regulation of adherens junction organization GO:1903393 2 0.013
cellular response to alcohol GO:0097306 87 0.012
regulation of programmed cell death GO:0043067 341 0.012
regulation of catecholamine metabolic process GO:0042069 6 0.012
divalent inorganic cation transport GO:0072511 134 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
positive regulation of transferase activity GO:0051347 81 0.012
phenylpropanoid catabolic process GO:0046271 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
acute inflammatory response GO:0002526 58 0.012
protein activation cascade GO:0072376 12 0.012
negative regulation of neuron death GO:1901215 69 0.012
metanephros development GO:0001656 14 0.012
learning or memory GO:0007611 90 0.012
multi organism reproductive process GO:0044703 262 0.012
positive regulation of blood coagulation GO:0030194 4 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
regulation of calcium ion transport GO:0051924 77 0.012
adult locomotory behavior GO:0008344 4 0.012
coagulation GO:0050817 28 0.012
branching morphogenesis of an epithelial tube GO:0048754 14 0.012
hormone metabolic process GO:0042445 69 0.012
negative regulation of coagulation GO:0050819 7 0.012
regulation of epithelial cell migration GO:0010632 17 0.012
cerebellar granule cell precursor proliferation GO:0021930 1 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.011
negative regulation of hemostasis GO:1900047 6 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
liver development GO:0001889 90 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
ossification GO:0001503 70 0.011
apoptotic process GO:0006915 381 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
heterocycle catabolic process GO:0046700 167 0.011
dephosphorylation GO:0016311 98 0.011
developmental growth GO:0048589 100 0.011
multicellular organism growth GO:0035264 1 0.011
connective tissue development GO:0061448 33 0.011
positive regulation of apoptotic signaling pathway GO:2001235 6 0.011
positive regulation of cell communication GO:0010647 271 0.011
cell migration GO:0016477 197 0.011
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
negative regulation of gene expression GO:0010629 199 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
localization of cell GO:0051674 202 0.010
cellular response to metal ion GO:0071248 55 0.010
skeletal system development GO:0001501 41 0.010
immune system process GO:0002376 204 0.010
positive regulation of camp metabolic process GO:0030816 31 0.010
regulation of bmp signaling pathway GO:0030510 2 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
negative regulation of immune system process GO:0002683 39 0.010
regulation of protein processing GO:0070613 50 0.010
regulation of inflammatory response GO:0050727 48 0.010
cellular response to thyroid hormone stimulus GO:0097067 5 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
negative regulation of response to biotic stimulus GO:0002832 4 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
response to corticosterone GO:0051412 40 0.010

Pgcp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.081
disease of anatomical entity DOID:7 0 0.081
eye and adnexa disease DOID:1492 0 0.081
nervous system disease DOID:863 0 0.081
eye disease DOID:5614 0 0.081
retinal disease DOID:5679 0 0.056
disease of metabolism DOID:0014667 0 0.044
inherited metabolic disorder DOID:655 0 0.044
retinal degeneration DOID:8466 0 0.028
degeneration of macula and posterior pole DOID:2007 0 0.028
macular degeneration DOID:4448 0 0.028
age related macular degeneration DOID:10871 0 0.028
carbohydrate metabolic disorder DOID:2978 0 0.012
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
bone development disease DOID:0080006 0 0.010
bone disease DOID:0080001 0 0.010