Rattus norvegicus

0 known processes

Phyhip

phytanoyl-CoA 2-hydroxylase interacting protein

Phyhip biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.220
negative regulation of multicellular organismal process GO:0051241 203 0.208
regulation of cell differentiation GO:0045595 320 0.170
nucleobase containing small molecule metabolic process GO:0055086 316 0.139
negative regulation of nervous system development GO:0051961 79 0.101
nucleotide metabolic process GO:0009117 279 0.093
regulation of cell development GO:0060284 263 0.087
regulation of cellular component organization GO:0051128 368 0.087
neuron projection development GO:0031175 273 0.082
nucleoside phosphate metabolic process GO:0006753 283 0.079
cell morphogenesis GO:0000902 142 0.070
regulation of nervous system development GO:0051960 264 0.070
ribose phosphate metabolic process GO:0019693 235 0.068
purine nucleotide metabolic process GO:0006163 229 0.064
organonitrogen compound catabolic process GO:1901565 179 0.063
negative regulation of cell development GO:0010721 82 0.062
transcription dna templated GO:0006351 377 0.062
organelle organization GO:0006996 266 0.062
potassium ion transport GO:0006813 97 0.062
locomotion GO:0040011 237 0.060
regulation of catalytic activity GO:0050790 304 0.058
cation transport GO:0006812 382 0.058
negative regulation of neuron differentiation GO:0045665 62 0.058
regulation of neurogenesis GO:0050767 247 0.055
negative regulation of cell differentiation GO:0045596 99 0.055
positive regulation of phosphorus metabolic process GO:0010562 262 0.055
cell part morphogenesis GO:0032990 123 0.055
regulation of neuron projection development GO:0010975 161 0.053
nucleoside triphosphate metabolic process GO:0009141 144 0.053
regulation of rna metabolic process GO:0051252 391 0.052
cell projection organization GO:0030030 302 0.052
ribose phosphate biosynthetic process GO:0046390 87 0.050
regulation of purine nucleotide metabolic process GO:1900542 115 0.049
cytoskeleton organization GO:0007010 111 0.049
purine ribonucleotide metabolic process GO:0009150 227 0.049
purine ribonucleoside catabolic process GO:0046130 124 0.048
negative regulation of neuron projection development GO:0010977 46 0.047
camp metabolic process GO:0046058 63 0.047
purine containing compound metabolic process GO:0072521 253 0.046
carbohydrate derivative metabolic process GO:1901135 346 0.046
neuron development GO:0048666 286 0.045
purine ribonucleotide catabolic process GO:0009154 136 0.045
cellular component movement GO:0006928 248 0.044
secretion by cell GO:0032940 248 0.043
actin filament based process GO:0030029 86 0.043
anatomical structure morphogenesis GO:0009653 298 0.043
negative regulation of developmental process GO:0051093 125 0.042
glial cell differentiation GO:0010001 65 0.042
positive regulation of cell differentiation GO:0045597 217 0.041
negative regulation of neurogenesis GO:0050768 78 0.041
cellular component morphogenesis GO:0032989 155 0.041
nucleoside metabolic process GO:0009116 179 0.040
purine nucleoside triphosphate metabolic process GO:0009144 141 0.040
positive regulation of cell development GO:0010720 176 0.040
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.039
purine nucleoside metabolic process GO:0042278 169 0.039
cell cell signaling GO:0007267 335 0.038
adrenergic receptor signaling pathway GO:0071875 9 0.038
positive regulation of response to stimulus GO:0048584 285 0.038
regulation of hydrolase activity GO:0051336 143 0.038
negative regulation of cellular component organization GO:0051129 83 0.037
programmed cell death GO:0012501 392 0.037
positive regulation of nucleotide metabolic process GO:0045981 91 0.036
regulation of cellular localization GO:0060341 263 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
regulation of membrane potential GO:0042391 110 0.035
organophosphate metabolic process GO:0019637 370 0.035
rna biosynthetic process GO:0032774 380 0.035
calcium ion homeostasis GO:0055074 162 0.034
regulation of neuron differentiation GO:0045664 208 0.034
nucleoside triphosphate catabolic process GO:0009143 123 0.034
central nervous system development GO:0007417 311 0.033
cellular nitrogen compound catabolic process GO:0044270 163 0.033
cardiac muscle cell contraction GO:0086003 10 0.033
regulation of ion transport GO:0043269 245 0.033
positive regulation of molecular function GO:0044093 230 0.033
nucleic acid templated transcription GO:0097659 379 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
cell projection morphogenesis GO:0048858 123 0.032
macromolecular complex assembly GO:0065003 273 0.032
ribonucleotide metabolic process GO:0009259 231 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
regulation of cell projection organization GO:0031344 175 0.032
cellular component biogenesis GO:0044085 368 0.031
calcium ion transport GO:0006816 131 0.031
purine containing compound catabolic process GO:0072523 138 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.030
response to hypoxia GO:0001666 231 0.030
regulation of transcription dna templated GO:0006355 374 0.030
response to alkaloid GO:0043279 132 0.030
glycosyl compound catabolic process GO:1901658 126 0.030
positive regulation of secretion GO:0051047 140 0.030
organic substance catabolic process GO:1901575 316 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
regulation of apoptotic process GO:0042981 335 0.030
purine nucleoside catabolic process GO:0006152 124 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
carbohydrate derivative catabolic process GO:1901136 147 0.030
response to electrical stimulus GO:0051602 56 0.029
ion homeostasis GO:0050801 212 0.029
secretion GO:0046903 307 0.029
negative regulation of metabolic process GO:0009892 331 0.029
ventricular cardiac muscle cell action potential GO:0086005 2 0.029
cellular component assembly GO:0022607 360 0.029
positive regulation of nervous system development GO:0051962 178 0.029
nucleoside catabolic process GO:0009164 126 0.028
protein oligomerization GO:0051259 191 0.028
organ morphogenesis GO:0009887 75 0.028
negative regulation of response to stimulus GO:0048585 155 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
nucleoside phosphate biosynthetic process GO:1901293 102 0.027
positive regulation of ion transport GO:0043270 94 0.027
nucleoside phosphate catabolic process GO:1901292 140 0.027
enzyme linked receptor protein signaling pathway GO:0007167 116 0.027
single organism organelle organization GO:1902589 180 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
regulation of protein metabolic process GO:0051246 289 0.026
nucleotide biosynthetic process GO:0009165 98 0.026
reproductive process GO:0022414 372 0.026
neurological system process GO:0050877 219 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
response to extracellular stimulus GO:0009991 380 0.025
sensory organ development GO:0007423 74 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
hormone secretion GO:0046879 115 0.025
positive regulation of transport GO:0051050 245 0.025
organic acid metabolic process GO:0006082 292 0.025
organ regeneration GO:0031100 101 0.024
organophosphate catabolic process GO:0046434 148 0.024
rhythmic process GO:0048511 156 0.024
positive regulation of hydrolase activity GO:0051345 86 0.024
ribonucleoside catabolic process GO:0042454 126 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
chemosensory behavior GO:0007635 2 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
homeostatic process GO:0042592 331 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
divalent metal ion transport GO:0070838 132 0.023
cell migration GO:0016477 197 0.023
apoptotic process GO:0006915 381 0.023
response to inorganic substance GO:0010035 377 0.023
cellular ion homeostasis GO:0006873 184 0.023
nucleobase containing compound catabolic process GO:0034655 152 0.023
metal ion homeostasis GO:0055065 186 0.022
positive regulation of nucleoside metabolic process GO:0045979 55 0.022
rna metabolic process GO:0016070 406 0.022
metal ion transport GO:0030001 289 0.022
head development GO:0060322 247 0.022
protein phosphorylation GO:0006468 345 0.022
sensory perception GO:0007600 101 0.022
response to cytokine GO:0034097 215 0.022
cell cycle GO:0007049 101 0.022
micturition GO:0060073 4 0.022
actin mediated cell contraction GO:0070252 12 0.022
cation transmembrane transport GO:0098655 263 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.021
negative regulation of cell communication GO:0010648 158 0.021
response to temperature stimulus GO:0009266 94 0.021
cell adhesion GO:0007155 110 0.020
regulation of secretion by cell GO:1903530 208 0.020
regulation of secretion GO:0051046 224 0.020
single organism behavior GO:0044708 130 0.020
response to ketone GO:1901654 182 0.020
positive regulation of protein kinase activity GO:0045860 73 0.020
body fluid secretion GO:0007589 41 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
chemical homeostasis GO:0048878 292 0.019
intracellular signal transduction GO:0035556 314 0.019
cellular cation homeostasis GO:0030003 180 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
regulation of membrane repolarization GO:0060306 1 0.019
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
catabolic process GO:0009056 351 0.019
mechanoreceptor differentiation GO:0042490 2 0.019
brain development GO:0007420 247 0.018
divalent inorganic cation transport GO:0072511 134 0.018
membrane repolarization GO:0086009 1 0.018
response to oxygen levels GO:0070482 265 0.018
aromatic compound catabolic process GO:0019439 168 0.018
positive regulation of signaling GO:0023056 270 0.018
cellular homeostasis GO:0019725 252 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
cation homeostasis GO:0055080 195 0.018
negative regulation of cell death GO:0060548 229 0.018
multi organism reproductive process GO:0044703 262 0.018
protein localization GO:0008104 191 0.018
gland development GO:0048732 155 0.018
neuron projection morphogenesis GO:0048812 122 0.018
single organism intracellular transport GO:1902582 166 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
response to ethanol GO:0045471 162 0.017
muscle contraction GO:0006936 88 0.017
cellular response to stress GO:0033554 269 0.017
muscle system process GO:0003012 115 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
saliva secretion GO:0046541 3 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
heart morphogenesis GO:0003007 3 0.017
cellular chemical homeostasis GO:0055082 247 0.016
negative regulation of cell projection organization GO:0031345 50 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
regulation of anatomical structure size GO:0090066 135 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
bmp signaling pathway GO:0030509 4 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
regulation of catabolic process GO:0009894 113 0.016
behavior GO:0007610 205 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
regulation of programmed cell death GO:0043067 341 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
protein complex assembly GO:0006461 263 0.016
purine containing compound biosynthetic process GO:0072522 85 0.016
leukocyte cell cell adhesion GO:0007159 4 0.016
neuromuscular process GO:0050905 2 0.016
urinary bladder smooth muscle contraction GO:0014832 4 0.016
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
macromolecule localization GO:0033036 252 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
macromolecular complex subunit organization GO:0043933 339 0.015
nucleotide catabolic process GO:0009166 139 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.015
regulation of response to stress GO:0080134 126 0.015
regulation of muscle system process GO:0090257 79 0.015
oxoacid metabolic process GO:0043436 290 0.015
negative regulation of secretion GO:0051048 82 0.015
dna integrity checkpoint GO:0031570 2 0.015
protein complex biogenesis GO:0070271 263 0.015
nucleoside monophosphate catabolic process GO:0009125 56 0.015
regulation of kinase activity GO:0043549 117 0.015
cell cycle checkpoint GO:0000075 2 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
regulation of signal transduction GO:0009966 318 0.015
negative regulation of secretion by cell GO:1903531 72 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
regulation of cardiac muscle contraction GO:0055117 17 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
biological adhesion GO:0022610 110 0.015
negative regulation of signaling GO:0023057 157 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
response to radiation GO:0009314 137 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
response to wounding GO:0009611 254 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
ras protein signal transduction GO:0007265 29 0.014
adult locomotory behavior GO:0008344 4 0.014
localization of cell GO:0051674 202 0.014
cell motility GO:0048870 202 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.014
circulatory system process GO:0003013 183 0.014
response to ammonium ion GO:0060359 71 0.014
positive regulation of protein modification process GO:0031401 142 0.014
single organism catabolic process GO:0044712 283 0.014
regulation of system process GO:0044057 208 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
regulation of cellular component movement GO:0051270 150 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
positive regulation of developmental process GO:0051094 283 0.014
cardiac conduction GO:0061337 2 0.014
circulatory system development GO:0072359 134 0.014
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
regulation of organelle organization GO:0033043 80 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
heterocycle catabolic process GO:0046700 167 0.013
reproduction GO:0000003 245 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
regulation of cell proliferation GO:0042127 359 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
cellular amine metabolic process GO:0044106 38 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
actin filament based movement GO:0030048 16 0.013
acid secretion GO:0046717 48 0.013
cellular catabolic process GO:0044248 295 0.013
inner ear receptor cell differentiation GO:0060113 2 0.013
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.013
detection of external stimulus GO:0009581 13 0.013
dicarboxylic acid transport GO:0006835 34 0.013
regulation of actin filament based movement GO:1903115 12 0.013
positive regulation of catabolic process GO:0009896 78 0.013
respiratory gaseous exchange GO:0007585 4 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
actin cytoskeleton organization GO:0030036 73 0.012
negative regulation of response to tumor cell GO:0002835 2 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
response to decreased oxygen levels GO:0036293 237 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.012
atp catabolic process GO:0006200 54 0.012
organic acid transport GO:0015849 116 0.012
phosphatidylinositol dephosphorylation GO:0046856 4 0.012
amine metabolic process GO:0009308 38 0.012
circadian rhythm GO:0007623 88 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of cell growth GO:0001558 85 0.012
response to nutrient levels GO:0031667 370 0.012
ovulation cycle GO:0042698 67 0.012
regulation of muscle contraction GO:0006937 53 0.012
detection of stimulus GO:0051606 24 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of cellular response to stress GO:0080135 49 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
positive regulation of heart contraction GO:0045823 15 0.012
positive regulation of cell communication GO:0010647 271 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
urinary tract smooth muscle contraction GO:0014848 4 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
growth GO:0040007 165 0.011
regulation of sensory perception GO:0051931 29 0.011
nitrogen compound transport GO:0071705 229 0.011
protein homotetramerization GO:0051289 25 0.011
cardiac ventricle development GO:0003231 1 0.011
cofactor metabolic process GO:0051186 95 0.011
regulation of actin filament based process GO:0032970 42 0.011
protein homooligomerization GO:0051260 91 0.011
cell growth GO:0016049 104 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
serotonin receptor signaling pathway GO:0007210 10 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
action potential GO:0001508 54 0.011
response to hydrogen peroxide GO:0042542 89 0.011
negative regulation of transport GO:0051051 136 0.011
male gonad development GO:0008584 59 0.011
heart development GO:0007507 72 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
protein complex subunit organization GO:0071822 302 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
organic anion transport GO:0015711 132 0.011
regulation of molecular function GO:0065009 398 0.011
positive regulation of signal transduction GO:0009967 175 0.011
positive regulation of gene expression GO:0010628 244 0.011
olfactory behavior GO:0042048 2 0.011
lipid metabolic process GO:0006629 283 0.011
forebrain development GO:0030900 98 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.010
positive regulation of multicellular organismal process GO:0051240 387 0.010
gonad development GO:0008406 104 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
peptide secretion GO:0002790 86 0.010
single organism reproductive process GO:0044702 297 0.010
regulation of immune system process GO:0002682 123 0.010
positive regulation of transferase activity GO:0051347 81 0.010
rhythmic behavior GO:0007622 24 0.010
heart process GO:0003015 57 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
regulation of dendrite development GO:0050773 59 0.010
positive regulation of nucleotide catabolic process GO:0030813 53 0.010

Phyhip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.047
muscular disease DOID:0080000 0 0.047
heart disease DOID:114 0 0.047
cardiomyopathy DOID:0050700 0 0.047
disease of anatomical entity DOID:7 0 0.047
intrinsic cardiomyopathy DOID:0060036 0 0.047
cardiovascular system disease DOID:1287 0 0.047
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.047
musculoskeletal system disease DOID:17 0 0.047
muscle tissue disease DOID:66 0 0.047
nervous system disease DOID:863 0 0.043
long qt syndrome DOID:2843 0 0.021
sensory system disease DOID:0050155 0 0.019
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016