Rattus norvegicus

49 known processes

Pigl

phosphatidylinositol glycan anchor biosynthesis, class L

Pigl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of hormone secretion GO:0046883 106 0.144
nucleic acid templated transcription GO:0097659 379 0.132
cell cell signaling GO:0007267 335 0.106
male mating behavior GO:0060179 3 0.103
single organism reproductive process GO:0044702 297 0.096
cellular chemical homeostasis GO:0055082 247 0.094
lipid metabolic process GO:0006629 283 0.088
calcium ion homeostasis GO:0055074 162 0.083
secretion by cell GO:0032940 248 0.082
positive regulation of nucleic acid templated transcription GO:1903508 197 0.081
regulation of secretion GO:0051046 224 0.080
ion transmembrane transport GO:0034220 365 0.078
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.076
small molecule biosynthetic process GO:0044283 124 0.076
regulation of ion transport GO:0043269 245 0.072
nitrogen compound transport GO:0071705 229 0.070
inorganic cation transmembrane transport GO:0098662 202 0.069
cellular homeostasis GO:0019725 252 0.069
organophosphate metabolic process GO:0019637 370 0.069
regulation of cellular localization GO:0060341 263 0.067
locomotion GO:0040011 237 0.065
organophosphate biosynthetic process GO:0090407 143 0.064
reproduction GO:0000003 245 0.063
nucleobase containing small molecule metabolic process GO:0055086 316 0.063
organonitrogen compound biosynthetic process GO:1901566 167 0.063
cation transport GO:0006812 382 0.063
regulation of phosphorus metabolic process GO:0051174 349 0.061
cellular calcium ion homeostasis GO:0006874 160 0.060
response to hypoxia GO:0001666 231 0.059
regulation of hormone levels GO:0010817 187 0.058
development of primary sexual characteristics GO:0045137 107 0.058
regulation of rna metabolic process GO:0051252 391 0.057
positive regulation of phosphate metabolic process GO:0045937 262 0.055
brain development GO:0007420 247 0.055
positive regulation of phosphorus metabolic process GO:0010562 262 0.055
metal ion homeostasis GO:0055065 186 0.054
single organism biosynthetic process GO:0044711 342 0.053
homeostatic process GO:0042592 331 0.053
central nervous system development GO:0007417 311 0.053
hormone transport GO:0009914 121 0.051
purine ribonucleotide metabolic process GO:0009150 227 0.050
g protein coupled receptor signaling pathway GO:0007186 242 0.050
alpha amino acid biosynthetic process GO:1901607 23 0.050
multicellular organism reproduction GO:0032504 233 0.049
monocarboxylic acid transport GO:0015718 52 0.049
cation homeostasis GO:0055080 195 0.049
nucleoside phosphate biosynthetic process GO:1901293 102 0.047
regulation of programmed cell death GO:0043067 341 0.046
regulation of secretion by cell GO:1903530 208 0.045
programmed cell death GO:0012501 392 0.045
negative regulation of transport GO:0051051 136 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.044
macromolecule localization GO:0033036 252 0.043
response to alkaloid GO:0043279 132 0.043
regulation of transcription dna templated GO:0006355 374 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
response to inorganic substance GO:0010035 377 0.041
ion homeostasis GO:0050801 212 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.041
regulation of phosphate metabolic process GO:0019220 349 0.041
single organism intracellular transport GO:1902582 166 0.040
camp metabolic process GO:0046058 63 0.040
transmembrane transport GO:0055085 412 0.040
multicellular organismal reproductive process GO:0048609 233 0.039
regulation of calcium ion transport GO:0051924 77 0.039
cation transmembrane transport GO:0098655 263 0.039
cellular divalent inorganic cation homeostasis GO:0072503 162 0.039
organic acid metabolic process GO:0006082 292 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
positive regulation of biosynthetic process GO:0009891 319 0.037
nucleoside phosphate metabolic process GO:0006753 283 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.037
organic acid transport GO:0015849 116 0.037
response to growth factor GO:0070848 189 0.036
cellular protein localization GO:0034613 122 0.036
spindle organization GO:0007051 2 0.036
rna metabolic process GO:0016070 406 0.035
nucleotide metabolic process GO:0009117 279 0.035
cellular ion homeostasis GO:0006873 184 0.035
inorganic ion transmembrane transport GO:0098660 229 0.034
apoptotic process GO:0006915 381 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
positive regulation of cell communication GO:0010647 271 0.032
reproductive process GO:0022414 372 0.032
purine containing compound biosynthetic process GO:0072522 85 0.032
regulation of respiratory gaseous exchange GO:0043576 2 0.032
cellular modified amino acid biosynthetic process GO:0042398 18 0.032
response to monosaccharide GO:0034284 159 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
organelle organization GO:0006996 266 0.031
carbohydrate derivative biosynthetic process GO:1901137 124 0.031
positive regulation of cell death GO:0010942 184 0.031
metal ion transport GO:0030001 289 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
positive regulation of transport GO:0051050 245 0.030
amide transport GO:0042886 105 0.030
head development GO:0060322 247 0.030
lipid biosynthetic process GO:0008610 128 0.029
intracellular signal transduction GO:0035556 314 0.029
positive regulation of secretion by cell GO:1903532 128 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
cellular component morphogenesis GO:0032989 155 0.029
regulation of signal transduction GO:0009966 318 0.028
signal release GO:0023061 145 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
response to metal ion GO:0010038 253 0.028
single organism organelle organization GO:1902589 180 0.028
hormone secretion GO:0046879 115 0.027
response to decreased oxygen levels GO:0036293 237 0.027
positive regulation of secretion GO:0051047 140 0.027
regulation of mapk cascade GO:0043408 116 0.027
regulation of camp biosynthetic process GO:0030817 38 0.027
cellular metal ion homeostasis GO:0006875 172 0.027
chemical homeostasis GO:0048878 292 0.027
calcium ion transmembrane transport GO:0070588 70 0.027
intracellular transport GO:0046907 185 0.027
signal transduction by phosphorylation GO:0023014 144 0.026
reproductive structure development GO:0048608 128 0.026
positive regulation of cell development GO:0010720 176 0.026
rna biosynthetic process GO:0032774 380 0.026
neurological system process GO:0050877 219 0.025
anion transport GO:0006820 178 0.025
single organismal cell cell adhesion GO:0016337 42 0.025
eye morphogenesis GO:0048592 4 0.025
leukocyte cell cell adhesion GO:0007159 4 0.025
asymmetric protein localization GO:0008105 2 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
gonad development GO:0008406 104 0.025
small gtpase mediated signal transduction GO:0007264 36 0.024
response to glucose GO:0009749 136 0.024
cellular cation homeostasis GO:0030003 180 0.024
calcium ion transport GO:0006816 131 0.024
cerebral cortex development GO:0021987 18 0.024
positive regulation of molecular function GO:0044093 230 0.024
respiratory gaseous exchange GO:0007585 4 0.024
carbohydrate metabolic process GO:0005975 130 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
regulation of insulin secretion GO:0050796 65 0.022
sex determination GO:0007530 2 0.022
purine nucleotide biosynthetic process GO:0006164 83 0.022
response to hexose GO:0009746 144 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
positive regulation of signal transduction GO:0009967 175 0.022
cyclic nucleotide metabolic process GO:0009187 80 0.022
feeding behavior GO:0007631 53 0.022
regulation of apoptotic process GO:0042981 335 0.021
synaptic transmission GO:0007268 235 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
ribonucleotide biosynthetic process GO:0009260 85 0.021
divalent inorganic cation transport GO:0072511 134 0.021
positive regulation of nucleotide metabolic process GO:0045981 91 0.021
regulation of anatomical structure size GO:0090066 135 0.021
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 2 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
protein localization GO:0008104 191 0.021
cellular component biogenesis GO:0044085 368 0.021
camp biosynthetic process GO:0006171 47 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
single organism behavior GO:0044708 130 0.021
purine containing compound metabolic process GO:0072521 253 0.021
cell migration GO:0016477 197 0.020
regulation of blood vessel endothelial cell migration GO:0043535 4 0.020
sexual reproduction GO:0019953 148 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
response to carbohydrate GO:0009743 183 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
regulation of neuron differentiation GO:0045664 208 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
regulation of system process GO:0044057 208 0.019
synaptic vesicle amine transport GO:0015842 3 0.019
sex differentiation GO:0007548 113 0.019
camera type eye morphogenesis GO:0048593 2 0.019
regulation of homeostatic process GO:0032844 101 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
negative regulation of secretion GO:0051048 82 0.019
peptidyl tyrosine phosphorylation GO:0018108 72 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
cytoplasmic transport GO:0016482 115 0.019
neuron fate commitment GO:0048663 4 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
response to oxygen levels GO:0070482 265 0.018
cytoskeleton organization GO:0007010 111 0.018
nucleoside catabolic process GO:0009164 126 0.018
secretion GO:0046903 307 0.018
protein oligomerization GO:0051259 191 0.018
behavior GO:0007610 205 0.018
retina morphogenesis in camera type eye GO:0060042 1 0.018
salivary gland development GO:0007431 3 0.018
organic hydroxy compound biosynthetic process GO:1901617 51 0.018
macromolecular complex assembly GO:0065003 273 0.018
mitotic spindle organization GO:0007052 2 0.018
negative regulation of signaling GO:0023057 157 0.017
gamete generation GO:0007276 124 0.017
regulation of cell differentiation GO:0045595 320 0.017
regulation of cell development GO:0060284 263 0.017
positive regulation of amine transport GO:0051954 26 0.017
cellular response to glucocorticoid stimulus GO:0071385 68 0.017
branching morphogenesis of an epithelial tube GO:0048754 14 0.017
asymmetric stem cell division GO:0098722 2 0.017
regulation of b cell differentiation GO:0045577 1 0.017
carboxylic acid transport GO:0046942 115 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
regulation of neurogenesis GO:0050767 247 0.017
mapk cascade GO:0000165 140 0.017
nucleotide biosynthetic process GO:0009165 98 0.016
negative regulation of cell death GO:0060548 229 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.016
positive regulation of hormone secretion GO:0046887 65 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
protein complex subunit organization GO:0071822 302 0.016
regulation of membrane potential GO:0042391 110 0.016
regulation of catalytic activity GO:0050790 304 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
oxoacid metabolic process GO:0043436 290 0.016
monoamine transport GO:0015844 43 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
organ formation GO:0048645 3 0.016
positive regulation of signaling GO:0023056 270 0.016
circulatory system process GO:0003013 183 0.016
visual perception GO:0007601 3 0.015
chromosome segregation GO:0007059 2 0.015
protein complex assembly GO:0006461 263 0.015
transcription dna templated GO:0006351 377 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
response to oxidative stress GO:0006979 186 0.015
peptide hormone secretion GO:0030072 84 0.015
cell cycle GO:0007049 101 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
cellular modified amino acid metabolic process GO:0006575 61 0.015
angioblast cell migration GO:0035476 1 0.015
regulation of cellular component movement GO:0051270 150 0.015
male germ line stem cell asymmetric division GO:0048133 1 0.015
developmental process involved in reproduction GO:0003006 159 0.015
lymphocyte migration GO:0072676 3 0.015
regulation of molecular function GO:0065009 398 0.014
cellular carbohydrate metabolic process GO:0044262 72 0.014
sequestering of metal ion GO:0051238 9 0.014
maintenance of location GO:0051235 17 0.014
regulation of peptide transport GO:0090087 87 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
cellular lipid metabolic process GO:0044255 208 0.014
anatomical structure homeostasis GO:0060249 29 0.014
response to external biotic stimulus GO:0043207 221 0.014
cellular component assembly GO:0022607 360 0.014
positive regulation of locomotion GO:0040017 102 0.014
muscle contraction GO:0006936 88 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
regulation of kinase activity GO:0043549 117 0.014
organophosphate catabolic process GO:0046434 148 0.014
sequestering of calcium ion GO:0051208 8 0.014
peptide secretion GO:0002790 86 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
negative regulation of metabolic process GO:0009892 331 0.013
organic substance catabolic process GO:1901575 316 0.013
response to anoxia GO:0034059 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
reproductive system development GO:0061458 128 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
oxidation reduction process GO:0055114 304 0.013
cell part morphogenesis GO:0032990 123 0.013
sensory perception GO:0007600 101 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
cellular ketone metabolic process GO:0042180 51 0.013
neuronal action potential GO:0019228 35 0.013
protein heterooligomerization GO:0051291 89 0.013
regulation of nervous system development GO:0051960 264 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of actin filament based process GO:0032970 42 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
anion transmembrane transport GO:0098656 77 0.013
divalent metal ion transport GO:0070838 132 0.013
regulation of phosphorylation GO:0042325 248 0.013
skeletal muscle cell differentiation GO:0035914 2 0.013
regulation of metal ion transport GO:0010959 118 0.013
visual learning GO:0008542 8 0.013
response to cytokine GO:0034097 215 0.013
action potential GO:0001508 54 0.013
respiratory system process GO:0003016 3 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of notch signaling pathway GO:0008593 3 0.012
embryonic pattern specification GO:0009880 1 0.012
establishment of protein localization GO:0045184 141 0.012
cognition GO:0050890 92 0.012
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.012
stem cell division GO:0017145 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
negative regulation of cell matrix adhesion GO:0001953 3 0.012
learning or memory GO:0007611 90 0.012
inflammatory response GO:0006954 150 0.012
neuron differentiation GO:0030182 368 0.012
positive regulation of adenylate cyclase activity GO:0045762 12 0.012
olfactory learning GO:0008355 1 0.012
regulation of tube size GO:0035150 89 0.012
adult locomotory behavior GO:0008344 4 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
neuron projection development GO:0031175 273 0.012
cellular component movement GO:0006928 248 0.012
regulation of blood vessel size GO:0050880 89 0.012
regulation of blood pressure GO:0008217 83 0.012
alcohol biosynthetic process GO:0046165 38 0.012
glycogen biosynthetic process GO:0005978 15 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
cell projection organization GO:0030030 302 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
positive regulation of gene expression GO:0010628 244 0.011
blood circulation GO:0008015 183 0.011
regulation of camp metabolic process GO:0030814 43 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
negative regulation of signal transduction GO:0009968 83 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
regulation of amine transport GO:0051952 54 0.011
protein transport GO:0015031 132 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
cellular catabolic process GO:0044248 295 0.011
organic anion transport GO:0015711 132 0.011
positive regulation of endothelial cell migration GO:0010595 4 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
fatty acid metabolic process GO:0006631 99 0.011
glucose homeostasis GO:0042593 75 0.011
growth GO:0040007 165 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
response to histamine GO:0034776 3 0.011
somatic stem cell division GO:0048103 2 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
positive regulation of developmental process GO:0051094 283 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
ras protein signal transduction GO:0007265 29 0.011
response to amphetamine GO:0001975 25 0.011
cell motility GO:0048870 202 0.010
nucleotide catabolic process GO:0009166 139 0.010
male gamete generation GO:0048232 99 0.010
dna metabolic process GO:0006259 96 0.010
regulation of protein transport GO:0051223 68 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
cyclic nucleotide biosynthetic process GO:0009190 63 0.010
response to nutrient levels GO:0031667 370 0.010

Pigl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
eye and adnexa disease DOID:1492 0 0.071
retinal disease DOID:5679 0 0.071
disease of anatomical entity DOID:7 0 0.071
retinal degeneration DOID:8466 0 0.071
nervous system disease DOID:863 0 0.071
sensory system disease DOID:0050155 0 0.071
eye disease DOID:5614 0 0.071
retinitis pigmentosa DOID:10584 0 0.018