Rattus norvegicus

48 known processes

Pitx1

paired-like homeodomain 1

(Aliases: Bft)

Pitx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.363
regulation of transcription dna templated GO:0006355 374 0.341
regulation of rna metabolic process GO:0051252 391 0.278
regulation of cell proliferation GO:0042127 359 0.241
transcription dna templated GO:0006351 377 0.218
regulation of nucleic acid templated transcription GO:1903506 380 0.217
nucleic acid templated transcription GO:0097659 379 0.156
positive regulation of gene expression GO:0010628 244 0.127
Mouse Rat Worm
response to nutrient levels GO:0031667 370 0.118
Rat
cellular component morphogenesis GO:0032989 155 0.112
Worm Fly
lipid metabolic process GO:0006629 283 0.111
positive regulation of cell proliferation GO:0008284 249 0.107
regulation of rna biosynthetic process GO:2001141 381 0.107
cellular metal ion homeostasis GO:0006875 172 0.097
tissue development GO:0009888 252 0.095
Mouse
transmission of nerve impulse GO:0019226 42 0.080
positive regulation of nucleic acid templated transcription GO:1903508 197 0.079
Mouse Rat Worm
transcription from rna polymerase ii promoter GO:0006366 252 0.071
Mouse Rat Worm
positive regulation of rna metabolic process GO:0051254 203 0.069
Mouse Rat Worm
metal ion transport GO:0030001 289 0.067
regulation of molecular function GO:0065009 398 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.064
negative regulation of cell proliferation GO:0008285 119 0.064
organic acid metabolic process GO:0006082 292 0.063
organic acid biosynthetic process GO:0016053 83 0.062
circulatory system development GO:0072359 134 0.061
positive regulation of biosynthetic process GO:0009891 319 0.059
Mouse Rat Worm
response to peptide GO:1901652 292 0.058
secretion GO:0046903 307 0.058
response to peptide hormone GO:0043434 278 0.057
regulation of secretion GO:0051046 224 0.056
regulation of ion transport GO:0043269 245 0.055
chemical homeostasis GO:0048878 292 0.055
negative regulation of osteoblast differentiation GO:0045668 2 0.055
rna biosynthetic process GO:0032774 380 0.053
aging GO:0007568 241 0.053
multi organism reproductive process GO:0044703 262 0.052
wound healing GO:0042060 122 0.052
regulation of growth GO:0040008 105 0.052
negative regulation of metabolic process GO:0009892 331 0.051
axonogenesis GO:0007409 71 0.048
Worm
regulation of metal ion transport GO:0010959 118 0.048
positive regulation of transport GO:0051050 245 0.048
regulation of protein metabolic process GO:0051246 289 0.047
positive regulation of transcription dna templated GO:0045893 197 0.047
Mouse Rat Worm
cellular response to oxygen containing compound GO:1901701 386 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.046
Mouse Rat Worm
positive regulation of secretion by cell GO:1903532 128 0.046
multi multicellular organism process GO:0044706 138 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.045
regulation of catalytic activity GO:0050790 304 0.044
response to extracellular stimulus GO:0009991 380 0.044
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
Mouse Rat Worm
cell growth GO:0016049 104 0.042
cell projection organization GO:0030030 302 0.041
Worm Fly
response to inorganic substance GO:0010035 377 0.041
cell morphogenesis involved in differentiation GO:0000904 119 0.041
Worm Fly
response to metal ion GO:0010038 253 0.041
neuron projection guidance GO:0097485 24 0.041
Worm
regulation of anatomical structure size GO:0090066 135 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
Mouse Rat Worm
cellular lipid metabolic process GO:0044255 208 0.040
cytosolic calcium ion homeostasis GO:0051480 140 0.040
negative regulation of molecular function GO:0044092 133 0.040
cation transport GO:0006812 382 0.040
regulation of multicellular organismal development GO:2000026 376 0.040
oxoacid metabolic process GO:0043436 290 0.039
macromolecule localization GO:0033036 252 0.039
regulation of signal transduction GO:0009966 318 0.039
regulation of secretion by cell GO:1903530 208 0.039
negative regulation of transport GO:0051051 136 0.039
cellular response to stress GO:0033554 269 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
multicellular organismal reproductive process GO:0048609 233 0.038
secretion by cell GO:0032940 248 0.038
protein maturation GO:0051604 68 0.037
locomotion GO:0040011 237 0.037
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
Mouse Rat Worm
chemotaxis GO:0006935 66 0.036
Worm
cellular ketone metabolic process GO:0042180 51 0.036
regulation of hydrolase activity GO:0051336 143 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
cellular amine metabolic process GO:0044106 38 0.035
inorganic ion transmembrane transport GO:0098660 229 0.035
regulation of cellular component organization GO:0051128 368 0.035
neuron differentiation GO:0030182 368 0.035
Rat Worm Fly
neuron projection morphogenesis GO:0048812 122 0.034
Worm Fly
negative regulation of multicellular organismal process GO:0051241 203 0.034
regulation of cellular localization GO:0060341 263 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
cytokine secretion GO:0050663 15 0.034
regulation of anatomical structure morphogenesis GO:0022603 141 0.032
carboxylic acid metabolic process GO:0019752 289 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
Mouse Rat Worm
negative regulation of gene expression GO:0010629 199 0.031
nitrogen compound transport GO:0071705 229 0.031
homeostatic process GO:0042592 331 0.031
cell morphogenesis GO:0000902 142 0.031
Worm Fly
carboxylic acid transport GO:0046942 115 0.031
programmed cell death GO:0012501 392 0.030
neuron development GO:0048666 286 0.030
Worm Fly
axon development GO:0061564 96 0.030
Worm
response to wounding GO:0009611 254 0.030
transmembrane transport GO:0055085 412 0.030
oxidation reduction process GO:0055114 304 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
Mouse Rat Worm
regulation of cell differentiation GO:0045595 320 0.028
tonic smooth muscle contraction GO:0014820 4 0.028
response to estradiol GO:0032355 164 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
response to nutrient GO:0007584 248 0.028
Rat
anatomical structure morphogenesis GO:0009653 298 0.028
Mouse Rat Worm Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
multicellular organismal signaling GO:0035637 44 0.026
lipid biosynthetic process GO:0008610 128 0.026
positive regulation of secretion GO:0051047 140 0.026
regulation of cell growth GO:0001558 85 0.026
divalent metal ion transport GO:0070838 132 0.026
small molecule biosynthetic process GO:0044283 124 0.025
regulation of apoptotic process GO:0042981 335 0.025
reproductive process GO:0022414 372 0.025
Rat
organ formation GO:0048645 3 0.025
negative regulation of biosynthetic process GO:0009890 168 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
Mouse Rat Worm
positive regulation of hydrolase activity GO:0051345 86 0.025
reproduction GO:0000003 245 0.025
muscle structure development GO:0061061 87 0.024
Mouse
intracellular signal transduction GO:0035556 314 0.024
cation homeostasis GO:0055080 195 0.024
developmental growth GO:0048589 100 0.024
cation transmembrane transport GO:0098655 263 0.024
positive regulation of developmental process GO:0051094 283 0.024
apoptotic process GO:0006915 381 0.024
cellular chemical homeostasis GO:0055082 247 0.024
cardiac muscle tissue growth GO:0055017 20 0.023
monocarboxylic acid metabolic process GO:0032787 152 0.023
embryonic skeletal system development GO:0048706 3 0.022
positive regulation of signaling GO:0023056 270 0.022
growth GO:0040007 165 0.022
response to ketone GO:1901654 182 0.022
amine metabolic process GO:0009308 38 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
positive regulation of molecular function GO:0044093 230 0.021
regulation of body fluid levels GO:0050878 90 0.021
protein processing GO:0016485 68 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular homeostasis GO:0019725 252 0.021
vesicle mediated transport GO:0016192 181 0.021
multicellular organism growth GO:0035264 1 0.021
cellular carbohydrate metabolic process GO:0044262 72 0.021
ion homeostasis GO:0050801 212 0.021
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
neuron projection development GO:0031175 273 0.020
Worm Fly
response to biotic stimulus GO:0009607 226 0.020
icosanoid metabolic process GO:0006690 38 0.020
regulation of cell projection organization GO:0031344 175 0.020
ion transmembrane transport GO:0034220 365 0.020
regulation of stem cell differentiation GO:2000736 2 0.020
single organism biosynthetic process GO:0044711 342 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
response to estrogen GO:0043627 232 0.020
axon guidance GO:0007411 24 0.020
Worm
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
single organism reproductive process GO:0044702 297 0.019
Rat
immune system process GO:0002376 204 0.019
negative regulation of cell differentiation GO:0045596 99 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
steroid metabolic process GO:0008202 73 0.019
cellular component assembly GO:0022607 360 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.018
organelle organization GO:0006996 266 0.018
cardiovascular system development GO:0072358 134 0.018
salivary gland development GO:0007431 3 0.018
taxis GO:0042330 67 0.018
Worm
monocarboxylic acid biosynthetic process GO:0072330 48 0.017
divalent inorganic cation transport GO:0072511 134 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
organic acid transport GO:0015849 116 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
positive regulation of catabolic process GO:0009896 78 0.017
cellular response to external stimulus GO:0071496 118 0.017
negative regulation of cell death GO:0060548 229 0.017
motor neuron axon guidance GO:0008045 1 0.017
protein localization GO:0008104 191 0.016
negative regulation of growth GO:0045926 37 0.016
calcium ion transport GO:0006816 131 0.016
proteolysis GO:0006508 175 0.016
unsaturated fatty acid metabolic process GO:0033559 39 0.016
reproductive system development GO:0061458 128 0.016
Rat
regulation of organ formation GO:0003156 2 0.016
muscle cell differentiation GO:0042692 52 0.016
Mouse
glycosyl compound metabolic process GO:1901657 182 0.016
cell part morphogenesis GO:0032990 123 0.016
Worm Fly
cellular ion homeostasis GO:0006873 184 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
calcium ion homeostasis GO:0055074 162 0.015
epithelium development GO:0060429 96 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
catabolic process GO:0009056 351 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
organic anion transport GO:0015711 132 0.015
ras protein signal transduction GO:0007265 29 0.015
epithelial cell proliferation GO:0050673 54 0.015
response to glucocorticoid GO:0051384 223 0.015
regulation of organ growth GO:0046620 13 0.015
positive regulation of cell death GO:0010942 184 0.015
heart development GO:0007507 72 0.015
cellular component biogenesis GO:0044085 368 0.015
protein phosphorylation GO:0006468 345 0.015
artery smooth muscle contraction GO:0014824 4 0.015
central nervous system development GO:0007417 311 0.015
Mouse Rat
lipid localization GO:0010876 62 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
regulation of locomotion GO:0040012 148 0.014
Worm
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.014
calcium ion transmembrane transport GO:0070588 70 0.014
regulation of systemic arterial blood pressure GO:0003073 30 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of cell motility GO:2000145 131 0.014
insulin like growth factor receptor signaling pathway GO:0048009 3 0.014
cellular cation homeostasis GO:0030003 180 0.014
female pregnancy GO:0007565 122 0.014
positive regulation of cell communication GO:0010647 271 0.014
regulation of programmed cell death GO:0043067 341 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of blood vessel size GO:0050880 89 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
specification of organ identity GO:0010092 2 0.013
organ morphogenesis GO:0009887 75 0.013
Rat
heart morphogenesis GO:0003007 3 0.013
regulation of calcium ion transport GO:0051924 77 0.013
response to insulin GO:0032868 133 0.013
phospholipid metabolic process GO:0006644 61 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
neural crest cell migration GO:0001755 1 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
cellular catabolic process GO:0044248 295 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
establishment of protein localization GO:0045184 141 0.013
regulation of muscle tissue development GO:1901861 25 0.013
negative regulation of protein processing GO:0010955 47 0.013
anion transport GO:0006820 178 0.013
neurological system process GO:0050877 219 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
sensory organ development GO:0007423 74 0.013
regulation of muscle organ development GO:0048634 26 0.013
response to calcium ion GO:0051592 59 0.012
regulation of nervous system development GO:0051960 264 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
defense response GO:0006952 194 0.012
sexual reproduction GO:0019953 148 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
regulation of protein transport GO:0051223 68 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of protein modification process GO:0031399 194 0.012
regulation of heart growth GO:0060420 12 0.012
regulation of hormone levels GO:0010817 187 0.012
protein secretion GO:0009306 34 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
multicellular organism reproduction GO:0032504 233 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
response to oxygen levels GO:0070482 265 0.012
regulation of cell migration GO:0030334 128 0.012
regulation of response to external stimulus GO:0032101 106 0.012
axis specification GO:0009798 4 0.012
regulation of proteolysis GO:0030162 66 0.012
cell cell signaling GO:0007267 335 0.012
cellular response to acid chemical GO:0071229 75 0.012
negative regulation of proteolysis GO:0045861 41 0.012
cell cycle GO:0007049 101 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
metal ion homeostasis GO:0055065 186 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
response to growth factor GO:0070848 189 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
negative regulation of organ growth GO:0046621 3 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
intracellular transport GO:0046907 185 0.011
action potential GO:0001508 54 0.011
saliva secretion GO:0046541 3 0.011
retinal ganglion cell axon guidance GO:0031290 1 0.011
purine containing compound metabolic process GO:0072521 253 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of protein kinase activity GO:0045859 105 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
male gamete generation GO:0048232 99 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
regulation of neuron projection development GO:0010975 161 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
cytokine production GO:0001816 61 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
regeneration GO:0031099 163 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
response to chromate GO:0046687 3 0.011
response to lipopolysaccharide GO:0032496 191 0.010
regulation of fatty acid metabolic process GO:0019217 18 0.010
negative regulation of cardiac muscle tissue development GO:0055026 3 0.010
cellular response to lipid GO:0071396 201 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
cellular component movement GO:0006928 248 0.010
Worm
response to decreased oxygen levels GO:0036293 237 0.010
sensory perception of bitter taste GO:0050913 4 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
regulation of homeostatic process GO:0032844 101 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
regulation of epithelial cell proliferation GO:0050678 49 0.010
monoamine transport GO:0015844 43 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
single organism organelle organization GO:1902589 180 0.010
protein complex biogenesis GO:0070271 263 0.010
endothelial cell proliferation GO:0001935 20 0.010
glycogen metabolic process GO:0005977 23 0.010
glycerolipid metabolic process GO:0046486 67 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010

Pitx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
Human
nervous system disease DOID:863 0 0.028
integumentary system disease DOID:16 0 0.010
sensory system disease DOID:0050155 0 0.010