Rattus norvegicus

40 known processes

Plcb1

phospholipase C, beta 1 (phosphoinositide-specific)

(Aliases: PLC'1,RATPHOSPHB,PLCbeta1,Phosphb)

Plcb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.179
regulation of cellular component organization GO:0051128 368 0.150
Mouse
regulation of phosphorylation GO:0042325 248 0.150
Human
cell projection organization GO:0030030 302 0.142
positive regulation of response to stimulus GO:0048584 285 0.138
Human
apoptotic process GO:0006915 381 0.134
carbohydrate derivative metabolic process GO:1901135 346 0.133
Human Mouse
regulation of programmed cell death GO:0043067 341 0.130
positive regulation of multicellular organismal process GO:0051240 387 0.127
Mouse Rat
regulation of locomotion GO:0040012 148 0.126
Mouse Rat
cellular response to endogenous stimulus GO:0071495 377 0.124
regulation of nervous system development GO:0051960 264 0.117
regulation of signal transduction GO:0009966 318 0.110
Human Mouse
neuron apoptotic process GO:0051402 88 0.107
intracellular signal transduction GO:0035556 314 0.106
Human Rat
regulation of cell projection organization GO:0031344 175 0.101
positive regulation of locomotion GO:0040017 102 0.098
Rat
positive regulation of developmental process GO:0051094 283 0.095
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 116 0.094
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.094
Mouse Rat
regulation of neuron projection development GO:0010975 161 0.091
negative regulation of cellular metabolic process GO:0031324 281 0.086
Mouse
regulation of multicellular organismal development GO:2000026 376 0.084
Mouse
response to growth factor GO:0070848 189 0.083
organelle organization GO:0006996 266 0.081
Mouse
regulation of neuron death GO:1901214 115 0.081
nucleobase containing small molecule metabolic process GO:0055086 316 0.078
Human
positive regulation of cellular component organization GO:0051130 200 0.078
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.076
regulation of phosphorus metabolic process GO:0051174 349 0.074
Human Rat
neuron projection development GO:0031175 273 0.072
positive regulation of neurogenesis GO:0050769 165 0.072
locomotion GO:0040011 237 0.069
Mouse Rat
rna metabolic process GO:0016070 406 0.069
Mouse
positive regulation of nervous system development GO:0051962 178 0.069
metal ion transport GO:0030001 289 0.068
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.067
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.065
positive regulation of cell communication GO:0010647 271 0.065
Human
neuron development GO:0048666 286 0.065
response to purine containing compound GO:0014074 126 0.065
Rat
positive regulation of neuron projection development GO:0010976 99 0.064
positive regulation of catalytic activity GO:0043085 184 0.064
Human
purine ribonucleotide metabolic process GO:0009150 227 0.062
Human
cell type specific apoptotic process GO:0097285 134 0.061
neuron differentiation GO:0030182 368 0.061
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
Mouse Rat
regulation of cell development GO:0060284 263 0.060
Mouse
catabolic process GO:0009056 351 0.060
Human Rat
negative regulation of signaling GO:0023057 157 0.060
regulation of cellular protein metabolic process GO:0032268 267 0.059
carboxylic acid transport GO:0046942 115 0.059
anion transport GO:0006820 178 0.059
cellular response to stress GO:0033554 269 0.058
Human
motor neuron axon guidance GO:0008045 1 0.058
regulation of phosphate metabolic process GO:0019220 349 0.057
Human Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.057
Mouse
guanosine containing compound metabolic process GO:1901068 74 0.057
Human
regulation of apoptotic process GO:0042981 335 0.057
cellular response to organic cyclic compound GO:0071407 202 0.056
carboxylic acid metabolic process GO:0019752 289 0.056
negative regulation of cell death GO:0060548 229 0.056
positive regulation of cell migration GO:0030335 96 0.056
Rat
organic anion transport GO:0015711 132 0.056
axon ensheathment GO:0008366 40 0.055
regulation of mapk cascade GO:0043408 116 0.053
Human
purine containing compound metabolic process GO:0072521 253 0.053
Human
regulation of neuron differentiation GO:0045664 208 0.052
positive regulation of programmed cell death GO:0043068 157 0.052
regulation of cellular component movement GO:0051270 150 0.051
Mouse Rat
cell morphogenesis GO:0000902 142 0.051
negative regulation of cell communication GO:0010648 158 0.051
positive regulation of cell differentiation GO:0045597 217 0.051
Mouse
regulation of neuron apoptotic process GO:0043523 83 0.050
central nervous system development GO:0007417 311 0.050
Mouse
purine containing compound catabolic process GO:0072523 138 0.050
Human
regulation of protein metabolic process GO:0051246 289 0.049
Mouse
ribose phosphate metabolic process GO:0019693 235 0.049
Human
regulation of cell differentiation GO:0045595 320 0.049
Mouse
positive regulation of cell development GO:0010720 176 0.049
response to hypoxia GO:0001666 231 0.049
positive regulation of biosynthetic process GO:0009891 319 0.049
Mouse Rat
organophosphate metabolic process GO:0019637 370 0.049
transmembrane transport GO:0055085 412 0.048
Rat
brain development GO:0007420 247 0.048
Mouse
cellular component morphogenesis GO:0032989 155 0.048
neuron death GO:0070997 127 0.048
negative regulation of metabolic process GO:0009892 331 0.047
Mouse
cellular cation homeostasis GO:0030003 180 0.046
Rat
organic substance catabolic process GO:1901575 316 0.046
Human Rat
cell motility GO:0048870 202 0.045
Mouse Rat
transcription dna templated GO:0006351 377 0.044
Mouse
cellular response to growth factor stimulus GO:0071363 162 0.044
nucleotide metabolic process GO:0009117 279 0.044
Human
cellular response to oxygen containing compound GO:1901701 386 0.044
nitrogen compound transport GO:0071705 229 0.044
Rat
cgmp biosynthetic process GO:0006182 15 0.044
regulation of ion transport GO:0043269 245 0.044
Rat
single organism catabolic process GO:0044712 283 0.043
Human Rat
organic acid metabolic process GO:0006082 292 0.043
mapk cascade GO:0000165 140 0.043
Human
single organism carbohydrate metabolic process GO:0044723 118 0.043
Rat
positive regulation of apoptotic process GO:0043065 154 0.043
chemical homeostasis GO:0048878 292 0.042
Rat
transmission of nerve impulse GO:0019226 42 0.042
neurological system process GO:0050877 219 0.042
single organism biosynthetic process GO:0044711 342 0.042
Rat
protein phosphorylation GO:0006468 345 0.041
inorganic ion transmembrane transport GO:0098660 229 0.041
Rat
cell part morphogenesis GO:0032990 123 0.041
head development GO:0060322 247 0.041
Mouse
oxoacid metabolic process GO:0043436 290 0.041
regulation of purine nucleotide metabolic process GO:1900542 115 0.041
Human
amine metabolic process GO:0009308 38 0.040
regulation of intracellular signal transduction GO:1902531 218 0.040
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.040
secretion GO:0046903 307 0.040
Mouse Rat
behavior GO:0007610 205 0.040
regulation of membrane potential GO:0042391 110 0.040
cellular calcium ion homeostasis GO:0006874 160 0.040
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
Human Rat
response to inorganic substance GO:0010035 377 0.040
Rat
positive regulation of cell proliferation GO:0008284 249 0.039
positive regulation of nucleoside metabolic process GO:0045979 55 0.039
Human
response to peptide hormone GO:0043434 278 0.039
divalent inorganic cation homeostasis GO:0072507 165 0.039
Rat
regulation of synaptic transmission GO:0050804 141 0.039
ion transmembrane transport GO:0034220 365 0.039
Rat
organic acid transport GO:0015849 116 0.039
glycosyl compound metabolic process GO:1901657 182 0.038
Human
multicellular organismal signaling GO:0035637 44 0.038
regulation of molecular function GO:0065009 398 0.038
Human Rat
cellular response to organonitrogen compound GO:0071417 197 0.038
second messenger mediated signaling GO:0019932 51 0.038
positive regulation of transport GO:0051050 245 0.038
Mouse Rat
macromolecular complex subunit organization GO:0043933 339 0.037
positive regulation of signaling GO:0023056 270 0.037
Human
regulation of hydrolase activity GO:0051336 143 0.037
Human Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
Human Mouse
regulation of hormone levels GO:0010817 187 0.037
nucleobase containing compound catabolic process GO:0034655 152 0.036
Human
cellular divalent inorganic cation homeostasis GO:0072503 162 0.036
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.036
Human
neuronal action potential GO:0019228 35 0.036
amino acid transport GO:0006865 70 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
Mouse
regulation of anatomical structure size GO:0090066 135 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
Human Mouse
cellular catabolic process GO:0044248 295 0.035
Human Rat
regulation of cell morphogenesis GO:0022604 77 0.034
negative regulation of programmed cell death GO:0043069 183 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
cell morphogenesis involved in differentiation GO:0000904 119 0.034
cellular component biogenesis GO:0044085 368 0.034
regulation of transferase activity GO:0051338 123 0.034
regulation of cell proliferation GO:0042127 359 0.034
purine nucleoside triphosphate metabolic process GO:0009144 141 0.033
Human
negative regulation of cellular component organization GO:0051129 83 0.033
cellular ketone metabolic process GO:0042180 51 0.033
positive regulation of cell projection organization GO:0031346 111 0.032
neural crest cell differentiation GO:0014033 2 0.032
aromatic compound catabolic process GO:0019439 168 0.032
Human
macromolecular complex assembly GO:0065003 273 0.032
dendrite morphogenesis GO:0048813 43 0.032
cellular component assembly GO:0022607 360 0.032
cation homeostasis GO:0055080 195 0.032
Rat
negative regulation of apoptotic process GO:0043066 181 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.032
lipid metabolic process GO:0006629 283 0.031
regulation of dendrite morphogenesis GO:0048814 33 0.031
positive regulation of neuron differentiation GO:0045666 126 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
multi organism reproductive process GO:0044703 262 0.031
Mouse
nucleic acid templated transcription GO:0097659 379 0.030
Mouse
regulation of secretion by cell GO:1903530 208 0.030
Mouse Rat
anatomical structure morphogenesis GO:0009653 298 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
regulation of neurogenesis GO:0050767 247 0.030
regulation of peptide transport GO:0090087 87 0.030
negative regulation of neuron differentiation GO:0045665 62 0.030
regulation of secretion GO:0051046 224 0.029
Mouse Rat
regulation of protein phosphorylation GO:0001932 183 0.029
positive regulation of hydrolase activity GO:0051345 86 0.029
Human
purine nucleoside catabolic process GO:0006152 124 0.029
Human
response to decreased oxygen levels GO:0036293 237 0.028
metal ion homeostasis GO:0055065 186 0.028
Rat
positive regulation of odontogenesis of dentin containing tooth GO:0042488 1 0.028
regulation of response to stress GO:0080134 126 0.028
Human
regulation of transcription dna templated GO:0006355 374 0.028
Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.028
Mouse
cation transport GO:0006812 382 0.028
Rat
cellular amino acid metabolic process GO:0006520 107 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
cell adhesion GO:0007155 110 0.027
blood circulation GO:0008015 183 0.027
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.027
Rat
cell projection morphogenesis GO:0048858 123 0.027
cellular homeostasis GO:0019725 252 0.027
Rat
myelination GO:0042552 39 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.026
Human
heterocycle catabolic process GO:0046700 167 0.026
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.026
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 141 0.026
Human
positive regulation of protein phosphorylation GO:0001934 135 0.026
positive regulation of cell motility GO:2000147 97 0.026
Rat
fatty acid metabolic process GO:0006631 99 0.026
regulation of kinase activity GO:0043549 117 0.026
positive regulation of gtpase activity GO:0043547 47 0.026
Human
proteolysis GO:0006508 175 0.026
positive regulation of transcription factor import into nucleus GO:0042993 4 0.026
regulation of blood vessel size GO:0050880 89 0.026
regulation of nucleotide metabolic process GO:0006140 117 0.026
Human
growth GO:0040007 165 0.025
Mouse
rna biosynthetic process GO:0032774 380 0.025
Mouse
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
positive regulation of rap gtpase activity GO:0032854 4 0.025
cellular chemical homeostasis GO:0055082 247 0.025
Rat
negative regulation of nervous system development GO:0051961 79 0.025
carbohydrate metabolic process GO:0005975 130 0.025
Rat
cell cell signaling GO:0007267 335 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
Human
response to carbohydrate GO:0009743 183 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
Human Rat
small gtpase mediated signal transduction GO:0007264 36 0.025
nucleoside triphosphate catabolic process GO:0009143 123 0.025
Human
response to camp GO:0051591 91 0.025
regulation of metal ion transport GO:0010959 118 0.024
Rat
cellular amine metabolic process GO:0044106 38 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
regulation of synaptic plasticity GO:0048167 70 0.024
regulation of protein modification process GO:0031399 194 0.024
cyclic nucleotide metabolic process GO:0009187 80 0.024
protein localization GO:0008104 191 0.024
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.024
Mouse
circulatory system process GO:0003013 183 0.024
negative regulation of neuron death GO:1901215 69 0.024
divalent inorganic cation transport GO:0072511 134 0.024
Rat
response to organophosphorus GO:0046683 102 0.023
Rat
response to insulin GO:0032868 133 0.023
circulatory system development GO:0072359 134 0.023
negative regulation of neurogenesis GO:0050768 78 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
reactive oxygen species metabolic process GO:0072593 37 0.023
regulation of growth GO:0040008 105 0.023
Mouse
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
negative regulation of cell differentiation GO:0045596 99 0.023
protein homooligomerization GO:0051260 91 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
neuron projection morphogenesis GO:0048812 122 0.023
central nervous system neuron axonogenesis GO:0021955 1 0.023
action potential GO:0001508 54 0.023
response to oxygen levels GO:0070482 265 0.023
Rat
macromolecule localization GO:0033036 252 0.023
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
response to extracellular stimulus GO:0009991 380 0.023
positive regulation of protein modification process GO:0031401 142 0.022
nucleoside phosphate catabolic process GO:1901292 140 0.022
Human
ras protein signal transduction GO:0007265 29 0.022
regulation of catalytic activity GO:0050790 304 0.022
Human Rat
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.022
monovalent inorganic cation transport GO:0015672 172 0.022
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.022
Human
multicellular organism reproduction GO:0032504 233 0.022
ion homeostasis GO:0050801 212 0.022
Rat
response to nutrient levels GO:0031667 370 0.022
regulation of cell motility GO:2000145 131 0.022
Mouse Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.022
Rat
retinal ganglion cell axon guidance GO:0031290 1 0.022
reactive nitrogen species metabolic process GO:2001057 1 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
Mouse
glycosyl compound catabolic process GO:1901658 126 0.021
Human
ribonucleotide metabolic process GO:0009259 231 0.021
Human
negative regulation of signal transduction GO:0009968 83 0.021
glutamate receptor signaling pathway GO:0007215 43 0.021
Mouse
positive regulation of transcription dna templated GO:0045893 197 0.021
Mouse
amide transport GO:0042886 105 0.021
cyclic nucleotide biosynthetic process GO:0009190 63 0.021
biological adhesion GO:0022610 110 0.021
purine nucleotide catabolic process GO:0006195 136 0.021
Human
cellular lipid metabolic process GO:0044255 208 0.021
regulation of catabolic process GO:0009894 113 0.021
Human
regulation of protein kinase activity GO:0045859 105 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
axonogenesis GO:0007409 71 0.020
response to nutrient GO:0007584 248 0.020
response to monosaccharide GO:0034284 159 0.020
muscle system process GO:0003012 115 0.020
regulation of catecholamine secretion GO:0050433 32 0.020
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.020
Human
positive regulation of protein metabolic process GO:0051247 178 0.020
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.020
protein complex assembly GO:0006461 263 0.020
immune system process GO:0002376 204 0.020
Mouse
negative regulation of cell projection organization GO:0031345 50 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
Human
regulation of cellular component biogenesis GO:0044087 86 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
dendrite development GO:0016358 72 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
Mouse
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
Mouse
tissue development GO:0009888 252 0.019
Mouse
small molecule biosynthetic process GO:0044283 124 0.019
Rat
chromosome segregation GO:0007059 2 0.019
regulation of dopamine secretion GO:0014059 15 0.019
positive regulation of signal transduction GO:0009967 175 0.019
Human
protein complex subunit organization GO:0071822 302 0.019
synaptic transmission GO:0007268 235 0.019
developmental growth GO:0048589 100 0.019
Mouse
cellular protein localization GO:0034613 122 0.019
positive regulation of cell death GO:0010942 184 0.018
regulation of calcium ion transport GO:0051924 77 0.018
Rat
reproductive process GO:0022414 372 0.018
Mouse
insulin receptor signaling pathway GO:0008286 24 0.018
positive regulation of ion transport GO:0043270 94 0.018
regulation of behavior GO:0050795 61 0.018
regulation of cell cycle g2 m phase transition GO:1902749 4 0.018
regulation of stress activated mapk cascade GO:0032872 23 0.018
Human
cellular metal ion homeostasis GO:0006875 172 0.017
Rat
regulation of system process GO:0044057 208 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
Human
regulation of rna metabolic process GO:0051252 391 0.017
Mouse
ribonucleotide biosynthetic process GO:0009260 85 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
Human
calcium ion transport GO:0006816 131 0.017
Rat
negative regulation of transport GO:0051051 136 0.017
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
Human
regulation of cellular localization GO:0060341 263 0.017
Mouse Rat
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
Human
single organism organelle organization GO:1902589 180 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
Human
regulation of cell growth GO:0001558 85 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.016
stress activated protein kinase signaling cascade GO:0031098 37 0.016
Human
peptide transport GO:0015833 97 0.016
peptide secretion GO:0002790 86 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.016
protein complex biogenesis GO:0070271 263 0.016
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
guanosine containing compound catabolic process GO:1901069 71 0.016
Human
multicellular organism growth GO:0035264 1 0.016
protein oligomerization GO:0051259 191 0.016
memory GO:0007613 54 0.016
divalent metal ion transport GO:0070838 132 0.016
Rat
response to cgmp GO:0070305 3 0.016
organic hydroxy compound transport GO:0015850 77 0.016
Rat
cell growth GO:0016049 104 0.016
embryonic skeletal system development GO:0048706 3 0.016
negative regulation of molecular function GO:0044092 133 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
Human
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
Mouse
response to wounding GO:0009611 254 0.016
regulation of proteolysis GO:0030162 66 0.016
cellular response to cgmp GO:0071321 2 0.015
positive regulation of synaptic transmission GO:0050806 62 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
Human
cellular response to insulin stimulus GO:0032869 81 0.015
cyclic purine nucleotide metabolic process GO:0052652 62 0.015
macromolecule catabolic process GO:0009057 58 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
Rat
purine nucleotide biosynthetic process GO:0006164 83 0.015
neurotrophin signaling pathway GO:0038179 18 0.015
regulation of gtpase activity GO:0043087 57 0.015
Human
gtp metabolic process GO:0046039 72 0.015
Human
positive regulation of secretion GO:0051047 140 0.015
Mouse Rat
purine ribonucleoside metabolic process GO:0046128 168 0.015
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
nucleotide biosynthetic process GO:0009165 98 0.015
response to peptide GO:1901652 292 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
Rat
regulation of response to external stimulus GO:0032101 106 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
regulation of gtp catabolic process GO:0033124 58 0.015
Human
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
Human
cellular response to oxygen levels GO:0071453 60 0.015
negative regulation of biosynthetic process GO:0009890 168 0.014
Mouse
learning or memory GO:0007611 90 0.014
response to herbicide GO:0009635 16 0.014
activation of protein kinase b activity GO:0032148 3 0.014
positive regulation of molecular function GO:0044093 230 0.014
Human
cellular response to peptide GO:1901653 133 0.014
hormone transport GO:0009914 121 0.014
cell migration GO:0016477 197 0.014
Mouse Rat
jnk cascade GO:0007254 28 0.014
Human
response to estrogen GO:0043627 232 0.014
response to ketone GO:1901654 182 0.014
nucleoside metabolic process GO:0009116 179 0.014
Human
multi multicellular organism process GO:0044706 138 0.014
taxis GO:0042330 67 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
Mouse
regulation of smooth muscle cell migration GO:0014910 36 0.014
response to reactive oxygen species GO:0000302 120 0.014
Rat
stress activated mapk cascade GO:0051403 35 0.014
Human
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
response to vitamin GO:0033273 131 0.014
sequestering of calcium ion GO:0051208 8 0.014
protein processing GO:0016485 68 0.014
cardiovascular system development GO:0072358 134 0.014
negative regulation of neuron projection development GO:0010977 46 0.014
neural crest cell development GO:0014032 2 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
negative regulation of neuron apoptotic process GO:0043524 45 0.014
cellular component movement GO:0006928 248 0.013
Mouse Rat
positive regulation of secretion by cell GO:1903532 128 0.013
Mouse Rat
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.013
Human
response to mineralocorticoid GO:0051385 49 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
amine transport GO:0015837 57 0.013
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.013
dopamine secretion GO:0014046 15 0.013
regulation of postsynaptic membrane potential GO:0060078 25 0.013
response to mechanical stimulus GO:0009612 134 0.013
homeostatic process GO:0042592 331 0.013
Rat
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
regulation of tube size GO:0035150 89 0.013
single organism intracellular transport GO:1902582 166 0.013
Rat
regulation of lipid metabolic process GO:0019216 68 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
Human
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
Human
regulation of cell migration GO:0030334 128 0.013
Mouse Rat
axon development GO:0061564 96 0.013
cellular response to camp GO:0071320 26 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
Human
heart development GO:0007507 72 0.013
response to glucocorticoid GO:0051384 223 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.012
positive regulation of kinase activity GO:0033674 77 0.012
single organism cellular localization GO:1902580 102 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
response to toxic substance GO:0009636 133 0.012
regulation of dendrite development GO:0050773 59 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
defense response GO:0006952 194 0.012
positive regulation of nucleotide catabolic process GO:0030813 53 0.012
Human
synapse organization GO:0050808 46 0.012
eye morphogenesis GO:0048592 4 0.012
response to activity GO:0014823 73 0.012
positive regulation of transferase activity GO:0051347 81 0.012
regulation of mrna 3 end processing GO:0031440 1 0.012
nucleotide catabolic process GO:0009166 139 0.012
Human
regulation of blood circulation GO:1903522 110 0.012
smooth muscle cell migration GO:0014909 36 0.012
response to glucose GO:0009749 136 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
forebrain development GO:0030900 98 0.012
Mouse
reproduction GO:0000003 245 0.012
Mouse
positive regulation of neuron apoptotic process GO:0043525 33 0.012
regulation of cellular component size GO:0032535 51 0.012
cellular ion homeostasis GO:0006873 184 0.012
Rat
camera type eye morphogenesis GO:0048593 2 0.012
regulation of homeostatic process GO:0032844 101 0.012
cellular response to hypoxia GO:0071456 51 0.012
regulation of amine transport GO:0051952 54 0.012
Rat
negative regulation of gene expression GO:0010629 199 0.012
Mouse
response to cytokine GO:0034097 215 0.012
Human
regulation of chemotaxis GO:0050920 29 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
female pregnancy GO:0007565 122 0.012
actin cytoskeleton organization GO:0030036 73 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
negative regulation of ion transport GO:0043271 51 0.011
Rat
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.011
wound healing GO:0042060 122 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
Rat
ribonucleoside catabolic process GO:0042454 126 0.011
Human
sexual reproduction GO:0019953 148 0.011
Mouse
anion transmembrane transport GO:0098656 77 0.011
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
Human
receptor localization to synapse GO:0097120 2 0.011
sequestering of metal ion GO:0051238 9 0.011
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.011
calcium ion homeostasis GO:0055074 162 0.011
Rat
mitotic sister chromatid separation GO:0051306 1 0.011
localization of cell GO:0051674 202 0.011
Mouse Rat
skeletal system development GO:0001501 41 0.011
sensory perception GO:0007600 101 0.011
Rat
regulation of immune system process GO:0002682 123 0.011
Mouse
neuropeptide signaling pathway GO:0007218 29 0.011
negative regulation of developmental process GO:0051093 125 0.011
regulation of odontogenesis of dentin containing tooth GO:0042487 2 0.011

Plcb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
Human
nervous system disease DOID:863 0 0.037
Human
central nervous system disease DOID:331 0 0.032
Human
brain disease DOID:936 0 0.020
Human
vascular disease DOID:178 0 0.012
cardiovascular system disease DOID:1287 0 0.012
cerebral degeneration DOID:1443 0 0.011