Rattus norvegicus

0 known processes

Plk5

polo-like kinase 5

(Aliases: Plk5p)

Plk5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuron projection morphogenesis GO:0048812 122 0.043
oxoacid metabolic process GO:0043436 290 0.040
regulation of programmed cell death GO:0043067 341 0.038
neuron differentiation GO:0030182 368 0.037
Mouse
cellular component assembly GO:0022607 360 0.036
cellular response to organonitrogen compound GO:0071417 197 0.036
organic acid metabolic process GO:0006082 292 0.036
cell morphogenesis GO:0000902 142 0.035
response to inorganic substance GO:0010035 377 0.033
transcription dna templated GO:0006351 377 0.032
neuron projection development GO:0031175 273 0.032
Mouse
regulation of multicellular organismal development GO:2000026 376 0.032
Mouse
cellular component morphogenesis GO:0032989 155 0.032
chemotaxis GO:0006935 66 0.031
response to peptide hormone GO:0043434 278 0.031
cell part morphogenesis GO:0032990 123 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
cellular component movement GO:0006928 248 0.029
response to oxygen levels GO:0070482 265 0.028
single organism reproductive process GO:0044702 297 0.028
macromolecule localization GO:0033036 252 0.028
locomotion GO:0040011 237 0.028
cell morphogenesis involved in differentiation GO:0000904 119 0.028
head development GO:0060322 247 0.028
behavior GO:0007610 205 0.028
response to acid chemical GO:0001101 222 0.028
catabolic process GO:0009056 351 0.027
regulation of transcription dna templated GO:0006355 374 0.027
rna metabolic process GO:0016070 406 0.026
regulation of protein metabolic process GO:0051246 289 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
regulation of rna biosynthetic process GO:2001141 381 0.025
organophosphate metabolic process GO:0019637 370 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
regulation of cell projection organization GO:0031344 175 0.025
Mouse
developmental process involved in reproduction GO:0003006 159 0.025
cellular component biogenesis GO:0044085 368 0.025
cellular amino acid metabolic process GO:0006520 107 0.024
brain development GO:0007420 247 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
response to nutrient levels GO:0031667 370 0.024
cell projection organization GO:0030030 302 0.024
Mouse
transmembrane transport GO:0055085 412 0.024
axis specification GO:0009798 4 0.023
multi organism reproductive process GO:0044703 262 0.023
homeostatic process GO:0042592 331 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
apoptotic process GO:0006915 381 0.023
Mouse
adult locomotory behavior GO:0008344 4 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
response to carbohydrate GO:0009743 183 0.022
localization of cell GO:0051674 202 0.022
cellular response to stress GO:0033554 269 0.022
Mouse
response to extracellular stimulus GO:0009991 380 0.022
negative regulation of metabolic process GO:0009892 331 0.022
central nervous system development GO:0007417 311 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
cellular response to acid chemical GO:0071229 75 0.022
protein phosphorylation GO:0006468 345 0.021
rna biosynthetic process GO:0032774 380 0.021
sexual reproduction GO:0019953 148 0.021
taxis GO:0042330 67 0.021
cell migration GO:0016477 197 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
anterior posterior pattern specification GO:0009952 1 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
motor neuron axon guidance GO:0008045 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
cellular amine metabolic process GO:0044106 38 0.020
regulation of rna metabolic process GO:0051252 391 0.020
establishment of planar polarity GO:0001736 1 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
reproduction GO:0000003 245 0.020
synaptic transmission GO:0007268 235 0.019
regulation of molecular function GO:0065009 398 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
regulation of nervous system development GO:0051960 264 0.019
Mouse
positive regulation of molecular function GO:0044093 230 0.019
cell cell signaling GO:0007267 335 0.019
cellular ketone metabolic process GO:0042180 51 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
tissue development GO:0009888 252 0.019
amine metabolic process GO:0009308 38 0.019
multicellular organism reproduction GO:0032504 233 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
embryonic pattern specification GO:0009880 1 0.018
regulation of apoptotic process GO:0042981 335 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
regulation of cellular component organization GO:0051128 368 0.018
Mouse
cellular protein localization GO:0034613 122 0.018
organic substance catabolic process GO:1901575 316 0.018
reproductive process GO:0022414 372 0.018
response to decreased oxygen levels GO:0036293 237 0.018
positive regulation of cell communication GO:0010647 271 0.018
protein localization GO:0008104 191 0.018
response to insulin GO:0032868 133 0.018
cell motility GO:0048870 202 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
single organism organelle organization GO:1902589 180 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
gamete generation GO:0007276 124 0.017
regulation of catalytic activity GO:0050790 304 0.017
establishment of tissue polarity GO:0007164 2 0.017
dendrite development GO:0016358 72 0.017
cellular response to peptide GO:1901653 133 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
positive regulation of gene expression GO:0010628 244 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
non canonical wnt signaling pathway GO:0035567 3 0.016
cellular response to lipid GO:0071396 201 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
organelle organization GO:0006996 266 0.016
chemosensory behavior GO:0007635 2 0.015
growth GO:0040007 165 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
protein autophosphorylation GO:0046777 66 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
response to hypoxia GO:0001666 231 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
regulation of signal transduction GO:0009966 318 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
cellular catabolic process GO:0044248 295 0.015
single organism cellular localization GO:1902580 102 0.015
programmed cell death GO:0012501 392 0.015
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
response to ethanol GO:0045471 162 0.014
negative regulation of innate immune response GO:0045824 4 0.014
macromolecular complex assembly GO:0065003 273 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
single organism biosynthetic process GO:0044711 342 0.014
cell projection morphogenesis GO:0048858 123 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
nucleic acid templated transcription GO:0097659 379 0.014
proteolysis GO:0006508 175 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
nucleotide catabolic process GO:0009166 139 0.014
cation transport GO:0006812 382 0.014
regulation of neuron differentiation GO:0045664 208 0.014
Mouse
chemical homeostasis GO:0048878 292 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
regulation of cell development GO:0060284 263 0.014
Mouse
response to monosaccharide GO:0034284 159 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
ras protein signal transduction GO:0007265 29 0.013
organophosphate catabolic process GO:0046434 148 0.013
regulation of synaptic transmission GO:0050804 141 0.013
response to peptide GO:1901652 292 0.013
positive regulation of protein modification process GO:0031401 142 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
response to amino acid GO:0043200 75 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
Mouse
secretion by cell GO:0032940 248 0.013
regulation of cell differentiation GO:0045595 320 0.013
Mouse
regulation of cellular component biogenesis GO:0044087 86 0.013
single organism catabolic process GO:0044712 283 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
nucleotide metabolic process GO:0009117 279 0.013
response to ketone GO:1901654 182 0.013
neurological system process GO:0050877 219 0.013
divalent metal ion transport GO:0070838 132 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
Mouse
defense response GO:0006952 194 0.013
Mouse
hepaticobiliary system development GO:0061008 90 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
Mouse
protein complex subunit organization GO:0071822 302 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
signal release GO:0023061 145 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
olfactory behavior GO:0042048 2 0.012
negative regulation of cell death GO:0060548 229 0.012
response to glucose GO:0009749 136 0.012
peptidyl amino acid modification GO:0018193 126 0.012
response to nutrient GO:0007584 248 0.012
secretion GO:0046903 307 0.012
neuron death GO:0070997 127 0.012
positive regulation of signaling GO:0023056 270 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
organ regeneration GO:0031100 101 0.012
positive regulation of nervous system development GO:0051962 178 0.012
Mouse
purine containing compound metabolic process GO:0072521 253 0.012
regulation of growth GO:0040008 105 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
regulation of neurogenesis GO:0050767 247 0.012
Mouse
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of ion transport GO:0043269 245 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
regulation of postsynaptic membrane potential GO:0060078 25 0.011
positive regulation of transport GO:0051050 245 0.011
response to oxidative stress GO:0006979 186 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
regulation of cell migration GO:0030334 128 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
multicellular organismal signaling GO:0035637 44 0.011
regulation of jnk cascade GO:0046328 19 0.011
learning or memory GO:0007611 90 0.011
cellular chemical homeostasis GO:0055082 247 0.011
spindle organization GO:0007051 2 0.011
metal ion transport GO:0030001 289 0.011
response to glucocorticoid GO:0051384 223 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
neuron development GO:0048666 286 0.011
Mouse
regulation of membrane potential GO:0042391 110 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
divalent inorganic cation transport GO:0072511 134 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to metal ion GO:0010038 253 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
positive regulation of signal transduction GO:0009967 175 0.011
negative regulation of gene expression GO:0010629 199 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
oxidation reduction process GO:0055114 304 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
response to growth factor GO:0070848 189 0.011
regulation of catabolic process GO:0009894 113 0.011
ion transmembrane transport GO:0034220 365 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of cell proliferation GO:0042127 359 0.011
Mouse
response to corticosteroid GO:0031960 235 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
response to hexose GO:0009746 144 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
response to toxic substance GO:0009636 133 0.010
nucleoside metabolic process GO:0009116 179 0.010
developmental growth GO:0048589 100 0.010
spermatogenesis GO:0007283 99 0.010
heart morphogenesis GO:0003007 3 0.010
vesicle mediated transport GO:0016192 181 0.010
rho protein signal transduction GO:0007266 11 0.010
protein oligomerization GO:0051259 191 0.010
multicellular organism growth GO:0035264 1 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
single organism behavior GO:0044708 130 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
Mouse

Plk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.025
disease of anatomical entity DOID:7 0 0.025
sensory system disease DOID:0050155 0 0.012
eye disease DOID:5614 0 0.012
eye and adnexa disease DOID:1492 0 0.012