Rattus norvegicus

0 known processes

Polr2b

polymerase (RNA) II (DNA directed) polypeptide B

Polr2b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.220
response to other organism GO:0051707 220 0.161
response to biotic stimulus GO:0009607 226 0.106
purine nucleoside monophosphate metabolic process GO:0009126 84 0.096
organophosphate metabolic process GO:0019637 370 0.084
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.072
dna geometric change GO:0032392 4 0.071
atp metabolic process GO:0046034 72 0.065
hair cell differentiation GO:0035315 2 0.064
oxoacid metabolic process GO:0043436 290 0.063
transcription dna templated GO:0006351 377 0.059
regulation of rna biosynthetic process GO:2001141 381 0.056
enzyme linked receptor protein signaling pathway GO:0007167 116 0.056
rna biosynthetic process GO:0032774 380 0.055
cellular response to stress GO:0033554 269 0.053
carboxylic acid metabolic process GO:0019752 289 0.052
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.052
response to external biotic stimulus GO:0043207 221 0.051
regulation of rna metabolic process GO:0051252 391 0.050
ribonucleotide catabolic process GO:0009261 136 0.049
nucleoside monophosphate metabolic process GO:0009123 93 0.047
negative regulation of signaling GO:0023057 157 0.047
ribonucleotide metabolic process GO:0009259 231 0.045
regulation of transcription dna templated GO:0006355 374 0.043
nucleoside metabolic process GO:0009116 179 0.042
nucleic acid templated transcription GO:0097659 379 0.041
purine nucleoside monophosphate catabolic process GO:0009128 55 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
negative regulation of rna biosynthetic process GO:1902679 118 0.038
nucleoside monophosphate catabolic process GO:0009125 56 0.035
rna processing GO:0006396 22 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
purine containing compound metabolic process GO:0072521 253 0.035
neuron differentiation GO:0030182 368 0.034
nitrogen compound transport GO:0071705 229 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
cellular response to endogenous stimulus GO:0071495 377 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
purine ribonucleoside metabolic process GO:0046128 168 0.032
glycosyl compound metabolic process GO:1901657 182 0.032
cell cell signaling GO:0007267 335 0.032
programmed cell death GO:0012501 392 0.031
trna metabolic process GO:0006399 4 0.031
atp catabolic process GO:0006200 54 0.030
ribonucleoside monophosphate metabolic process GO:0009161 88 0.030
nucleotide metabolic process GO:0009117 279 0.030
nucleobase containing compound catabolic process GO:0034655 152 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
cell cycle GO:0007049 101 0.029
purine nucleoside catabolic process GO:0006152 124 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
multicellular organism growth GO:0035264 1 0.028
mrna metabolic process GO:0016071 20 0.027
regulation of cell differentiation GO:0045595 320 0.027
dna templated transcription initiation GO:0006352 4 0.027
ncrna processing GO:0034470 3 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
dna metabolic process GO:0006259 96 0.026
cellular catabolic process GO:0044248 295 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
single organism catabolic process GO:0044712 283 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
regulation of mrna splicing via spliceosome GO:0048024 3 0.025
positive regulation of rna metabolic process GO:0051254 203 0.024
organic acid metabolic process GO:0006082 292 0.024
negative regulation of rna metabolic process GO:0051253 123 0.024
positive regulation of gene expression GO:0010628 244 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
negative regulation of apoptotic process GO:0043066 181 0.023
central nervous system development GO:0007417 311 0.023
dna duplex unwinding GO:0032508 3 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
synaptic transmission GO:0007268 235 0.023
negative regulation of signal transduction GO:0009968 83 0.023
negative regulation of cell communication GO:0010648 158 0.023
negative regulation of programmed cell death GO:0043069 183 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
regulation of cellular component organization GO:0051128 368 0.022
apoptotic process GO:0006915 381 0.022
negative regulation of cell death GO:0060548 229 0.022
heterocycle catabolic process GO:0046700 167 0.022
dna conformation change GO:0071103 10 0.022
single organism intracellular transport GO:1902582 166 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
catabolic process GO:0009056 351 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
mitotic cell cycle phase transition GO:0044772 20 0.021
neuromuscular synaptic transmission GO:0007274 2 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
behavior GO:0007610 205 0.020
purine nucleotide metabolic process GO:0006163 229 0.019
positive regulation of developmental process GO:0051094 283 0.019
ribonucleoside monophosphate catabolic process GO:0009158 55 0.019
cellular component biogenesis GO:0044085 368 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
response to acid chemical GO:0001101 222 0.018
regulation of nervous system development GO:0051960 264 0.018
negative regulation of metabolic process GO:0009892 331 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
positive regulation of nervous system development GO:0051962 178 0.018
regulation of intracellular signal transduction GO:1902531 218 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
secretion by cell GO:0032940 248 0.017
cellular amine metabolic process GO:0044106 38 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
neuron development GO:0048666 286 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
dna packaging GO:0006323 4 0.016
reproduction GO:0000003 245 0.015
response to nutrient GO:0007584 248 0.015
response to lipopolysaccharide GO:0032496 191 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
amine metabolic process GO:0009308 38 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.015
regulation of programmed cell death GO:0043067 341 0.015
regulation of signal transduction GO:0009966 318 0.015
regulation of apoptotic process GO:0042981 335 0.014
organ morphogenesis GO:0009887 75 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
regulation of neurogenesis GO:0050767 247 0.014
response to metal ion GO:0010038 253 0.014
response to mechanical stimulus GO:0009612 134 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cell cycle checkpoint GO:0000075 2 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
cellular lipid metabolic process GO:0044255 208 0.014
lipid metabolic process GO:0006629 283 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cell cycle phase transition GO:0044770 21 0.013
nucleotide catabolic process GO:0009166 139 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
response to radiation GO:0009314 137 0.013
chemical homeostasis GO:0048878 292 0.012
growth GO:0040007 165 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
regulation of cellular localization GO:0060341 263 0.012
oxidation reduction process GO:0055114 304 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
positive regulation of protein modification process GO:0031401 142 0.012
cellular component assembly GO:0022607 360 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of hormone levels GO:0010817 187 0.012
response to oxidative stress GO:0006979 186 0.012
mitochondrial rna metabolic process GO:0000959 1 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of growth GO:0040008 105 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
protein complex subunit organization GO:0071822 302 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
cellular homeostasis GO:0019725 252 0.012
alternative mrna splicing via spliceosome GO:0000380 4 0.012
macromolecular complex assembly GO:0065003 273 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
chemosensory behavior GO:0007635 2 0.011
molting cycle GO:0042303 3 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
response to oxygen levels GO:0070482 265 0.011
nucleoside catabolic process GO:0009164 126 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
gastrulation GO:0007369 2 0.011
brain development GO:0007420 247 0.011
response to estrogen GO:0043627 232 0.011
rna localization GO:0006403 4 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
dna integrity checkpoint GO:0031570 2 0.011
dna damage checkpoint GO:0000077 2 0.011
organophosphate catabolic process GO:0046434 148 0.011
regulation of immune system process GO:0002682 123 0.011
response to decreased oxygen levels GO:0036293 237 0.011
negative regulation of developmental process GO:0051093 125 0.011
positive regulation of cell proliferation GO:0008284 249 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
histone methylation GO:0016571 3 0.010
neurological system process GO:0050877 219 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010

Polr2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018