Rattus norvegicus

0 known processes

Pomc

proopiomelanocortin

(Aliases: Pomc1,Pomc2)

Pomc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.365
signal release GO:0023061 145 0.258
transcription from rna polymerase ii promoter GO:0006366 252 0.219
secretion by cell GO:0032940 248 0.208
regulation of calcium ion transport GO:0051924 77 0.201
positive regulation of ion transport GO:0043270 94 0.197
cation transmembrane transport GO:0098655 263 0.162
acid secretion GO:0046717 48 0.162
g protein coupled receptor signaling pathway GO:0007186 242 0.161
sodium ion transport GO:0006814 82 0.157
response to wounding GO:0009611 254 0.143
organophosphate metabolic process GO:0019637 370 0.140
inorganic cation transmembrane transport GO:0098662 202 0.135
cellular homeostasis GO:0019725 252 0.129
monovalent inorganic cation transport GO:0015672 172 0.128
cellular response to stress GO:0033554 269 0.126
response to radiation GO:0009314 137 0.121
secretion GO:0046903 307 0.114
cellular ion homeostasis GO:0006873 184 0.112
cell migration GO:0016477 197 0.111
vesicle mediated transport GO:0016192 181 0.103
positive regulation of gene expression GO:0010628 244 0.096
negative regulation of gene expression GO:0010629 199 0.095
smooth muscle cell apoptotic process GO:0034390 7 0.095
ion transmembrane transport GO:0034220 365 0.094
nucleotide metabolic process GO:0009117 279 0.090
regulation of neuron differentiation GO:0045664 208 0.089
cellular response to growth factor stimulus GO:0071363 162 0.088
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.084
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.084
regulation of ion transport GO:0043269 245 0.083
response to cytokine GO:0034097 215 0.083
homeostatic process GO:0042592 331 0.082
metal ion transport GO:0030001 289 0.081
cell cell signaling GO:0007267 335 0.081
positive regulation of secretion GO:0051047 140 0.080
organ regeneration GO:0031100 101 0.079
tissue development GO:0009888 252 0.079
regulation of cell differentiation GO:0045595 320 0.078
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.076
negative adaptation of signaling pathway GO:0022401 10 0.076
inorganic ion transmembrane transport GO:0098660 229 0.075
cellular component assembly GO:0022607 360 0.075
chemical homeostasis GO:0048878 292 0.074
positive regulation of nucleic acid templated transcription GO:1903508 197 0.073
response to glucose GO:0009749 136 0.072
response to hexose GO:0009746 144 0.072
response to monosaccharide GO:0034284 159 0.071
nucleobase containing small molecule metabolic process GO:0055086 316 0.071
response to alkaloid GO:0043279 132 0.067
purine containing compound metabolic process GO:0072521 253 0.067
negative regulation of transport GO:0051051 136 0.067
cellular chemical homeostasis GO:0055082 247 0.066
positive regulation of phosphate metabolic process GO:0045937 262 0.066
brain development GO:0007420 247 0.066
organic acid transport GO:0015849 116 0.065
divalent inorganic cation transport GO:0072511 134 0.065
negative regulation of biosynthetic process GO:0009890 168 0.065
regulation of hormone secretion GO:0046883 106 0.065
single organism reproductive process GO:0044702 297 0.064
sensory perception GO:0007600 101 0.064
response to inorganic substance GO:0010035 377 0.064
response to nutrient GO:0007584 248 0.063
divalent metal ion transport GO:0070838 132 0.063
negative regulation of transcription dna templated GO:0045892 116 0.062
response to growth factor GO:0070848 189 0.062
response to nutrient levels GO:0031667 370 0.061
negative regulation of signaling GO:0023057 157 0.060
regulation of phosphorus metabolic process GO:0051174 349 0.059
hormone secretion GO:0046879 115 0.058
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.058
calcium ion transport GO:0006816 131 0.058
transmembrane transport GO:0055085 412 0.058
circulatory system development GO:0072359 134 0.058
catecholamine transport GO:0051937 37 0.057
catecholamine secretion GO:0050432 33 0.057
peptide biosynthetic process GO:0043043 3 0.056
nitrogen compound transport GO:0071705 229 0.056
transcription dna templated GO:0006351 377 0.056
localization of cell GO:0051674 202 0.056
ribonucleotide metabolic process GO:0009259 231 0.056
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.055
positive regulation of transport GO:0051050 245 0.054
adaptation of signaling pathway GO:0023058 10 0.054
monoamine transport GO:0015844 43 0.053
neurological system process GO:0050877 219 0.052
cellular response to cytokine stimulus GO:0071345 127 0.051
rna metabolic process GO:0016070 406 0.051
ion homeostasis GO:0050801 212 0.050
carbohydrate derivative metabolic process GO:1901135 346 0.050
regulation of secretion GO:0051046 224 0.050
rna biosynthetic process GO:0032774 380 0.049
organic substance catabolic process GO:1901575 316 0.049
vasculature development GO:0001944 70 0.048
nucleoside phosphate metabolic process GO:0006753 283 0.047
negative regulation of cellular biosynthetic process GO:0031327 161 0.047
response to metal ion GO:0010038 253 0.047
reproductive process GO:0022414 372 0.047
regulation of transcription dna templated GO:0006355 374 0.045
regulation of rna metabolic process GO:0051252 391 0.044
regulation of catecholamine secretion GO:0050433 32 0.044
response to decreased oxygen levels GO:0036293 237 0.044
cell motility GO:0048870 202 0.044
organonitrogen compound biosynthetic process GO:1901566 167 0.044
response to oxygen levels GO:0070482 265 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
metal ion homeostasis GO:0055065 186 0.042
regulation of potassium ion transport GO:0043266 29 0.042
anion transport GO:0006820 178 0.041
regulation of system process GO:0044057 208 0.040
inflammatory response GO:0006954 150 0.040
programmed cell death GO:0012501 392 0.040
regulation of programmed cell death GO:0043067 341 0.039
regulation of amine transport GO:0051952 54 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
negative regulation of multicellular organismal process GO:0051241 203 0.039
blood vessel development GO:0001568 69 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.038
amine transport GO:0015837 57 0.038
purine ribonucleotide metabolic process GO:0009150 227 0.038
response to extracellular stimulus GO:0009991 380 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
cellular response to oxygen containing compound GO:1901701 386 0.036
regulation of sodium ion transport GO:0002028 21 0.036
regeneration GO:0031099 163 0.036
reproduction GO:0000003 245 0.036
negative regulation of metabolic process GO:0009892 331 0.036
cellular component biogenesis GO:0044085 368 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
negative regulation of amine transport GO:0051953 24 0.035
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
striated muscle contraction GO:0006941 44 0.035
regulation of cell development GO:0060284 263 0.035
regulation of rna biosynthetic process GO:2001141 381 0.035
defense response GO:0006952 194 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
response to ammonium ion GO:0060359 71 0.034
multicellular organism reproduction GO:0032504 233 0.034
catabolic process GO:0009056 351 0.034
macromolecular complex assembly GO:0065003 273 0.034
neuron differentiation GO:0030182 368 0.033
oxidation reduction process GO:0055114 304 0.033
cellular calcium ion homeostasis GO:0006874 160 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
cellular catabolic process GO:0044248 295 0.033
single organism carbohydrate metabolic process GO:0044723 118 0.033
sex differentiation GO:0007548 113 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.032
cellular response to abiotic stimulus GO:0071214 85 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
positive regulation of rna metabolic process GO:0051254 203 0.032
action potential GO:0001508 54 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
negative regulation of cell death GO:0060548 229 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
cardiovascular system development GO:0072358 134 0.031
positive regulation of neuron differentiation GO:0045666 126 0.031
regulation of nervous system development GO:0051960 264 0.031
purine ribonucleotide catabolic process GO:0009154 136 0.030
serotonin receptor signaling pathway GO:0007210 10 0.030
protein complex assembly GO:0006461 263 0.030
response to purine containing compound GO:0014074 126 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
negative regulation of nervous system development GO:0051961 79 0.030
regulation of phosphorylation GO:0042325 248 0.030
negative regulation of ion transport GO:0043271 51 0.030
regulation of homeostatic process GO:0032844 101 0.029
detection of stimulus GO:0051606 24 0.029
response to hypoxia GO:0001666 231 0.029
negative regulation of rna biosynthetic process GO:1902679 118 0.029
negative regulation of hormone secretion GO:0046888 46 0.029
response to ethanol GO:0045471 162 0.029
sodium ion transmembrane transport GO:0035725 67 0.028
mapk cascade GO:0000165 140 0.028
rhythmic process GO:0048511 156 0.028
heart morphogenesis GO:0003007 3 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
regulation of organ formation GO:0003156 2 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
cellular metal ion homeostasis GO:0006875 172 0.027
positive regulation of cell communication GO:0010647 271 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
apoptotic process GO:0006915 381 0.027
regulation of mapk cascade GO:0043408 116 0.027
regulation of ion transmembrane transport GO:0034765 121 0.027
desensitization of g protein coupled receptor protein signaling pathway by arrestin GO:0002032 1 0.027
amide transport GO:0042886 105 0.027
purine nucleotide metabolic process GO:0006163 229 0.027
regulation of homotypic cell cell adhesion GO:0034110 4 0.027
regulation of cellular catabolic process GO:0031329 101 0.026
potassium ion transport GO:0006813 97 0.026
response to carbohydrate GO:0009743 183 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
aromatic compound catabolic process GO:0019439 168 0.026
head development GO:0060322 247 0.026
cellular amine metabolic process GO:0044106 38 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.026
protein complex subunit organization GO:0071822 302 0.025
tube formation GO:0035148 3 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
lipid metabolic process GO:0006629 283 0.025
positive regulation of mapk cascade GO:0043410 92 0.025
urogenital system development GO:0001655 78 0.025
detection of visible light GO:0009584 3 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
tongue morphogenesis GO:0043587 3 0.025
regulation of cellular component organization GO:0051128 368 0.025
glucose homeostasis GO:0042593 75 0.025
positive regulation of secretion by cell GO:1903532 128 0.025
negative regulation of cell development GO:0010721 82 0.025
cellular amino acid metabolic process GO:0006520 107 0.024
circulatory system process GO:0003013 183 0.024
cellular component movement GO:0006928 248 0.024
regulation of peptide transport GO:0090087 87 0.024
negative regulation of cellular component organization GO:0051129 83 0.024
positive regulation of ion transmembrane transport GO:0034767 24 0.024
negative regulation of cell differentiation GO:0045596 99 0.024
muscle contraction GO:0006936 88 0.024
response to vitamin GO:0033273 131 0.024
protein complex biogenesis GO:0070271 263 0.024
regulation of behavior GO:0050795 61 0.024
cyclic nucleotide metabolic process GO:0009187 80 0.024
peptide secretion GO:0002790 86 0.023
positive regulation of cell development GO:0010720 176 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
glycosyl compound catabolic process GO:1901658 126 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
response to peptide hormone GO:0043434 278 0.023
positive regulation of molecular function GO:0044093 230 0.023
purine nucleoside triphosphate metabolic process GO:0009144 141 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.023
defecation GO:0030421 1 0.023
gliogenesis GO:0042063 93 0.023
negative regulation of cell communication GO:0010648 158 0.023
calcium ion homeostasis GO:0055074 162 0.023
synaptic transmission GO:0007268 235 0.023
muscle system process GO:0003012 115 0.022
nucleoside triphosphate metabolic process GO:0009141 144 0.022
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.022
positive regulation of signal transduction GO:0009967 175 0.022
heart process GO:0003015 57 0.022
regulation of peptide secretion GO:0002791 82 0.022
heterocycle catabolic process GO:0046700 167 0.022
nucleotide biosynthetic process GO:0009165 98 0.022
bone development GO:0060348 25 0.022
nucleic acid templated transcription GO:0097659 379 0.022
negative regulation of signal transduction GO:0009968 83 0.021
nucleoside triphosphate catabolic process GO:0009143 123 0.021
regulation of synaptic transmission GO:0050804 141 0.021
sensory perception of pain GO:0019233 73 0.021
negative regulation of secretion by cell GO:1903531 72 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
signal transduction by phosphorylation GO:0023014 144 0.021
cellular ketone metabolic process GO:0042180 51 0.021
aging GO:0007568 241 0.021
cellular cation homeostasis GO:0030003 180 0.021
purine ribonucleoside catabolic process GO:0046130 124 0.021
cellular potassium ion transport GO:0071804 72 0.021
organic hydroxy compound transport GO:0015850 77 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.021
positive regulation of hormone secretion GO:0046887 65 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
cellular response to oxygen levels GO:0071453 60 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.020
hormone transport GO:0009914 121 0.020
response to glucocorticoid GO:0051384 223 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
amide biosynthetic process GO:0043604 10 0.020
organic anion transport GO:0015711 132 0.020
behavior GO:0007610 205 0.020
organ formation GO:0048645 3 0.020
potassium ion transmembrane transport GO:0071805 71 0.020
positive regulation of neuron projection development GO:0010976 99 0.020
angiogenesis GO:0001525 53 0.020
regulation of neuron projection development GO:0010975 161 0.020
regulation of catabolic process GO:0009894 113 0.020
peptide hormone secretion GO:0030072 84 0.020
regulation of peptide hormone secretion GO:0090276 80 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.019
cellular response to reactive oxygen species GO:0034614 55 0.019
purine containing compound catabolic process GO:0072523 138 0.019
purine nucleoside triphosphate catabolic process GO:0009146 122 0.019
regulation of cell proliferation GO:0042127 359 0.019
carbohydrate catabolic process GO:0016052 40 0.019
central nervous system development GO:0007417 311 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
mesoderm development GO:0007498 2 0.019
single organism catabolic process GO:0044712 283 0.019
regulation of metal ion transport GO:0010959 118 0.019
negative regulation of neurogenesis GO:0050768 78 0.019
female gonad development GO:0008585 53 0.019
epithelial cell proliferation GO:0050673 54 0.019
peptide transport GO:0015833 97 0.019
intracellular signal transduction GO:0035556 314 0.019
macromolecule localization GO:0033036 252 0.019
morphogenesis of embryonic epithelium GO:0016331 3 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
locomotion GO:0040011 237 0.018
positive regulation of nervous system development GO:0051962 178 0.018
monocarboxylic acid transport GO:0015718 52 0.018
positive regulation of peptide secretion GO:0002793 52 0.018
regulation of transmembrane transporter activity GO:0022898 49 0.018
muscle cell apoptotic process GO:0010657 30 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.018
regulation of cell projection organization GO:0031344 175 0.018
apoptotic mitochondrial changes GO:0008637 10 0.018
cardiac ventricle development GO:0003231 1 0.018
cation homeostasis GO:0055080 195 0.018
response to temperature stimulus GO:0009266 94 0.018
immune system process GO:0002376 204 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
single organism biosynthetic process GO:0044711 342 0.018
regulation of apoptotic process GO:0042981 335 0.017
positive regulation of blood circulation GO:1903524 65 0.017
positive regulation of long term synaptic potentiation GO:1900273 4 0.017
biological adhesion GO:0022610 110 0.017
protein oligomerization GO:0051259 191 0.017
positive regulation of signaling GO:0023056 270 0.017
ribonucleotide biosynthetic process GO:0009260 85 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
response to corticosteroid GO:0031960 235 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
calcium ion import GO:0070509 22 0.017
regulation of blood pressure GO:0008217 83 0.017
cellular response to hypoxia GO:0071456 51 0.017
sensory perception of mechanical stimulus GO:0050954 17 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
regulation of insulin secretion GO:0050796 65 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
development of primary sexual characteristics GO:0045137 107 0.017
cell adhesion GO:0007155 110 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.017
reproductive system development GO:0061458 128 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
positive regulation of calcium ion transport GO:0051928 36 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
neuron projection development GO:0031175 273 0.016
insulin secretion GO:0030073 69 0.016
ras protein signal transduction GO:0007265 29 0.016
blood circulation GO:0008015 183 0.016
coronary vasculature morphogenesis GO:0060977 3 0.016
camp biosynthetic process GO:0006171 47 0.016
single organism carbohydrate catabolic process GO:0044724 40 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
ensheathment of neurons GO:0007272 40 0.016
regulation of locomotion GO:0040012 148 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
response to organophosphorus GO:0046683 102 0.016
feeding behavior GO:0007631 53 0.016
gland development GO:0048732 155 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.016
negative regulation of luteinizing hormone secretion GO:0033685 4 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
small gtpase mediated signal transduction GO:0007264 36 0.015
epithelium development GO:0060429 96 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.015
regulation of molecular function GO:0065009 398 0.015
positive regulation of peptide hormone secretion GO:0090277 50 0.015
positive regulation of transmembrane transport GO:0034764 25 0.015
glycerolipid metabolic process GO:0046486 67 0.015
ovulation cycle process GO:0022602 50 0.015
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
regulation of dopamine secretion GO:0014059 15 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
phospholipid metabolic process GO:0006644 61 0.015
neuronal action potential GO:0019228 35 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
regulation of neurogenesis GO:0050767 247 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
negative regulation of neuron differentiation GO:0045665 62 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
atp catabolic process GO:0006200 54 0.015
carbohydrate homeostasis GO:0033500 75 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
positive regulation of insulin secretion GO:0032024 36 0.015
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
regulation of inflammatory response GO:0050727 48 0.015
negative regulation of developmental process GO:0051093 125 0.015
muscle tissue morphogenesis GO:0060415 1 0.014
regulation of membrane potential GO:0042391 110 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
negative regulation of secretion GO:0051048 82 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
bmp signaling pathway GO:0030509 4 0.014
carboxylic acid transport GO:0046942 115 0.014
dephosphorylation GO:0016311 98 0.014
hair cell differentiation GO:0035315 2 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
heart development GO:0007507 72 0.014
positive regulation of cell death GO:0010942 184 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
response to fibroblast growth factor GO:0071774 29 0.014
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.014
regulation of body fluid levels GO:0050878 90 0.014
n methyl d aspartate receptor clustering GO:0097114 2 0.014
positive regulation of amine transport GO:0051954 26 0.013
renal system development GO:0072001 67 0.013
developmental process involved in reproduction GO:0003006 159 0.013
developmental induction GO:0031128 2 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
long term synaptic potentiation GO:0060291 21 0.013
connective tissue development GO:0061448 33 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
organic acid metabolic process GO:0006082 292 0.013
positive regulation of catabolic process GO:0009896 78 0.013
sexual reproduction GO:0019953 148 0.013
response to ionizing radiation GO:0010212 59 0.013
gamete generation GO:0007276 124 0.013
cytoplasmic transport GO:0016482 115 0.013
multicellular organismal movement GO:0050879 17 0.013
vasodilation GO:0042311 44 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
carbohydrate metabolic process GO:0005975 130 0.013
positive regulation of biomineral tissue development GO:0070169 4 0.013
protein homooligomerization GO:0051260 91 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
palate development GO:0060021 2 0.013
regulation of organelle organization GO:0033043 80 0.013
response to nicotine GO:0035094 51 0.013
positive regulation of smooth muscle cell apoptotic process GO:0034393 2 0.013
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.013
oxoacid metabolic process GO:0043436 290 0.013
cardiac muscle contraction GO:0060048 27 0.013
regulation of catalytic activity GO:0050790 304 0.013
regulation of cellular component movement GO:0051270 150 0.012
mesoderm formation GO:0001707 1 0.012
cellular response to interleukin 1 GO:0071347 37 0.012
detection of temperature stimulus GO:0016048 4 0.012
response to cocaine GO:0042220 39 0.012
positive regulation of catecholamine secretion GO:0033605 13 0.012
response to calcium ion GO:0051592 59 0.012
liver development GO:0001889 90 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
cellular response to monosaccharide stimulus GO:0071326 67 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
nucleoside metabolic process GO:0009116 179 0.012
response to toxic substance GO:0009636 133 0.012
generation of precursor metabolites and energy GO:0006091 62 0.012
diaphragm contraction GO:0002086 2 0.012
positive regulation of cell activation GO:0050867 34 0.012
cell projection organization GO:0030030 302 0.012
nucleoside catabolic process GO:0009164 126 0.012
regulation of hydrolase activity GO:0051336 143 0.012
embryonic placenta development GO:0001892 1 0.012
camp metabolic process GO:0046058 63 0.012
striated muscle tissue development GO:0014706 58 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
regulation of protein metabolic process GO:0051246 289 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
positive regulation of bone mineralization GO:0030501 4 0.011
regulation of response to external stimulus GO:0032101 106 0.011
dopamine secretion GO:0014046 15 0.011
detection of abiotic stimulus GO:0009582 13 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
nucleotide catabolic process GO:0009166 139 0.011
sensory perception of light stimulus GO:0050953 3 0.011
female sex differentiation GO:0046660 59 0.011
detection of external stimulus GO:0009581 13 0.011
regulation of muscle system process GO:0090257 79 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.011
positive regulation of developmental process GO:0051094 283 0.011
spermatogenesis GO:0007283 99 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
negative regulation of molecular function GO:0044092 133 0.011
g protein coupled receptor internalization GO:0002031 3 0.011

Pomc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.031
sensory system disease DOID:0050155 0 0.031
disease of anatomical entity DOID:7 0 0.031
vascular disease DOID:178 0 0.023
cardiovascular system disease DOID:1287 0 0.023
retinal disease DOID:5679 0 0.021
eye disease DOID:5614 0 0.021
eye and adnexa disease DOID:1492 0 0.021
retinal degeneration DOID:8466 0 0.021
retinitis pigmentosa DOID:10584 0 0.021
essential hypertension DOID:10825 0 0.015
artery disease DOID:0050828 0 0.015
hypertension DOID:10763 0 0.015
disease of metabolism DOID:0014667 0 0.014
central nervous system disease DOID:331 0 0.012