Rattus norvegicus

63 known processes

Pou2f3

POU class 2 homeobox 3

Pou2f3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism reproductive process GO:0044703 262 0.557
Rat Worm
response to inorganic substance GO:0010035 377 0.420
response to purine containing compound GO:0014074 126 0.399
urogenital system development GO:0001655 78 0.384
locomotion GO:0040011 237 0.289
Worm
cellular response to endogenous stimulus GO:0071495 377 0.265
blood vessel development GO:0001568 69 0.264
protein complex subunit organization GO:0071822 302 0.246
regulation of blood circulation GO:1903522 110 0.217
brain development GO:0007420 247 0.216
Rat
sexual reproduction GO:0019953 148 0.201
Rat Worm
aging GO:0007568 241 0.185
Worm
regulation of system process GO:0044057 208 0.162
multicellular organismal reproductive process GO:0048609 233 0.162
Rat Worm
cellular response to organic cyclic compound GO:0071407 202 0.162
response to nutrient levels GO:0031667 370 0.156
regulation of cell proliferation GO:0042127 359 0.156
anatomical structure formation involved in morphogenesis GO:0048646 83 0.154
regulation of tube size GO:0035150 89 0.145
cellular response to lipid GO:0071396 201 0.137
macromolecular complex assembly GO:0065003 273 0.136
regulation of molecular function GO:0065009 398 0.135
response to estrogen GO:0043627 232 0.132
kidney development GO:0001822 67 0.131
programmed cell death GO:0012501 392 0.129
circulatory system process GO:0003013 183 0.122
cell morphogenesis GO:0000902 142 0.120
response to camp GO:0051591 91 0.114
regulation of anatomical structure size GO:0090066 135 0.113
positive regulation of multicellular organismal process GO:0051240 387 0.110
anatomical structure morphogenesis GO:0009653 298 0.107
head development GO:0060322 247 0.107
Rat
male mating behavior GO:0060179 3 0.106
protein complex biogenesis GO:0070271 263 0.102
vascular process in circulatory system GO:0003018 96 0.099
insulin like growth factor receptor signaling pathway GO:0048009 3 0.098
gland development GO:0048732 155 0.098
Rat
cellular component movement GO:0006928 248 0.098
Worm
single organism reproductive process GO:0044702 297 0.098
Rat Worm
cellular component biogenesis GO:0044085 368 0.094
cellular calcium ion homeostasis GO:0006874 160 0.094
cellular response to organonitrogen compound GO:0071417 197 0.093
reproductive process GO:0022414 372 0.093
Rat Worm
reproduction GO:0000003 245 0.090
Rat Worm
developmental growth GO:0048589 100 0.088
regulation of intracellular signal transduction GO:1902531 218 0.088
circulatory system development GO:0072359 134 0.088
response to hypoxia GO:0001666 231 0.085
negative regulation of multicellular organismal process GO:0051241 203 0.084
Worm
positive regulation of signal transduction GO:0009967 175 0.080
positive regulation of response to stimulus GO:0048584 285 0.080
multicellular organism reproduction GO:0032504 233 0.080
Rat Worm
regulation of locomotion GO:0040012 148 0.078
tissue development GO:0009888 252 0.075
blood circulation GO:0008015 183 0.074
intracellular signal transduction GO:0035556 314 0.072
response to nutrient GO:0007584 248 0.071
central nervous system development GO:0007417 311 0.071
Rat Fly
response to vitamin d GO:0033280 34 0.070
vasculature development GO:0001944 70 0.070
angiogenesis GO:0001525 53 0.069
regulation of blood vessel size GO:0050880 89 0.067
homeostatic process GO:0042592 331 0.067
telencephalon development GO:0021537 62 0.067
regulation of ion transport GO:0043269 245 0.066
cellular component assembly GO:0022607 360 0.066
response to oxygen levels GO:0070482 265 0.066
nitrogen compound transport GO:0071705 229 0.065
g protein coupled receptor signaling pathway GO:0007186 242 0.064
response to extracellular stimulus GO:0009991 380 0.062
protein complex assembly GO:0006461 263 0.061
regulation of cell differentiation GO:0045595 320 0.061
Worm
positive regulation of blood circulation GO:1903524 65 0.061
metal ion transport GO:0030001 289 0.061
renal system development GO:0072001 67 0.059
transcription from rna polymerase ii promoter GO:0006366 252 0.059
response to metal ion GO:0010038 253 0.058
multi multicellular organism process GO:0044706 138 0.057
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.057
metal ion homeostasis GO:0055065 186 0.057
regulation of cellular component movement GO:0051270 150 0.054
cation transport GO:0006812 382 0.054
enzyme linked receptor protein signaling pathway GO:0007167 116 0.054
gamete generation GO:0007276 124 0.052
Rat Worm
comma shaped body morphogenesis GO:0072049 2 0.052
response to cytokine GO:0034097 215 0.052
developmental process involved in reproduction GO:0003006 159 0.052
Worm
heart process GO:0003015 57 0.049
neuron fate commitment GO:0048663 4 0.049
monovalent inorganic cation transport GO:0015672 172 0.048
cellular response to hormone stimulus GO:0032870 247 0.048
motor neuron axon guidance GO:0008045 1 0.047
cellular chemical homeostasis GO:0055082 247 0.047
protein phosphorylation GO:0006468 345 0.047
ion homeostasis GO:0050801 212 0.045
response to organophosphorus GO:0046683 102 0.045
negative regulation of response to stimulus GO:0048585 155 0.045
response to ketone GO:1901654 182 0.044
organ formation GO:0048645 3 0.044
regulation of cellular component organization GO:0051128 368 0.043
cell projection organization GO:0030030 302 0.043
development of primary sexual characteristics GO:0045137 107 0.043
regulation of programmed cell death GO:0043067 341 0.042
blood vessel morphogenesis GO:0048514 58 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.041
cardiovascular system development GO:0072358 134 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
wound healing GO:0042060 122 0.041
Mouse
thyroid gland development GO:0030878 1 0.041
axonogenesis GO:0007409 71 0.041
regulation of signal transduction GO:0009966 318 0.040
regulation of phosphorylation GO:0042325 248 0.040
response to reactive oxygen species GO:0000302 120 0.040
cell growth GO:0016049 104 0.039
transcription dna templated GO:0006351 377 0.039
response to oxidative stress GO:0006979 186 0.038
divalent inorganic cation homeostasis GO:0072507 165 0.038
cell motility GO:0048870 202 0.038
Worm
positive regulation of signaling GO:0023056 270 0.038
cell part morphogenesis GO:0032990 123 0.037
cellular ion homeostasis GO:0006873 184 0.037
regulation of transcription dna templated GO:0006355 374 0.036
apoptotic process GO:0006915 381 0.036
cell projection morphogenesis GO:0048858 123 0.036
positive regulation of molecular function GO:0044093 230 0.036
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
sodium ion transport GO:0006814 82 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
regulation of cell motility GO:2000145 131 0.035
negative regulation of cell differentiation GO:0045596 99 0.035
Worm
organonitrogen compound biosynthetic process GO:1901566 167 0.035
neuromuscular process GO:0050905 2 0.035
chemical homeostasis GO:0048878 292 0.034
cellular cation homeostasis GO:0030003 180 0.034
negative regulation of signaling GO:0023057 157 0.034
single organism biosynthetic process GO:0044711 342 0.034
neuron projection morphogenesis GO:0048812 122 0.034
regulation of cellular amine metabolic process GO:0033238 8 0.033
regeneration GO:0031099 163 0.033
actin mediated cell contraction GO:0070252 12 0.033
regulation of growth GO:0040008 105 0.033
axon development GO:0061564 96 0.033
regulation of neuron differentiation GO:0045664 208 0.032
cation homeostasis GO:0055080 195 0.032
embryo development GO:0009790 49 0.032
Worm
response to decreased oxygen levels GO:0036293 237 0.032
positive regulation of transferase activity GO:0051347 81 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
epithelium development GO:0060429 96 0.031
regulation of transferase activity GO:0051338 123 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
cell migration GO:0016477 197 0.029
Worm
response to wounding GO:0009611 254 0.029
Mouse
response to estradiol GO:0032355 164 0.029
regulation of cell growth GO:0001558 85 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.029
cellular homeostasis GO:0019725 252 0.029
cellular component morphogenesis GO:0032989 155 0.028
camp metabolic process GO:0046058 63 0.028
startle response GO:0001964 2 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
cellular amine metabolic process GO:0044106 38 0.028
negative regulation of secretion GO:0051048 82 0.028
response to food GO:0032094 27 0.027
adenohypophysis development GO:0021984 2 0.027
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
regulation of peptide hormone secretion GO:0090276 80 0.027
response to acid chemical GO:0001101 222 0.027
cellular response to nitrogen compound GO:1901699 210 0.026
amine metabolic process GO:0009308 38 0.026
somatostatin receptor signaling pathway GO:0038169 4 0.026
carbohydrate metabolic process GO:0005975 130 0.026
response to mechanical stimulus GO:0009612 134 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
Human Mouse Rat Fly
response to nicotine GO:0035094 51 0.025
vasodilation GO:0042311 44 0.025
negative regulation of cell communication GO:0010648 158 0.025
signal release GO:0023061 145 0.025
cellular macromolecular complex assembly GO:0034622 58 0.025
regulation of rna metabolic process GO:0051252 391 0.024
cellular response to stress GO:0033554 269 0.024
response to calcium ion GO:0051592 59 0.024
response to hexose GO:0009746 144 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
response to glucose GO:0009749 136 0.023
ion transmembrane transport GO:0034220 365 0.023
regulation of peptide transport GO:0090087 87 0.023
protein transport GO:0015031 132 0.023
hormone transport GO:0009914 121 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
regulation of metal ion transport GO:0010959 118 0.023
thyroid hormone generation GO:0006590 3 0.023
negative regulation of cell development GO:0010721 82 0.023
Worm
cellular response to alcohol GO:0097306 87 0.023
regulation of angiogenesis GO:0045765 39 0.022
regulation of vasoconstriction GO:0019229 44 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
transmembrane transport GO:0055085 412 0.022
establishment of protein localization GO:0045184 141 0.022
response to vitamin GO:0033273 131 0.022
positive regulation of growth GO:0045927 55 0.022
vesicle mediated transport GO:0016192 181 0.021
regulation of membrane potential GO:0042391 110 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
tube development GO:0035295 89 0.021
circadian rhythm GO:0007623 88 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
spermatogenesis GO:0007283 99 0.021
Rat
synaptic transmission GO:0007268 235 0.021
muscle structure development GO:0061061 87 0.021
regulation of cell development GO:0060284 263 0.020
Worm
peptide transport GO:0015833 97 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
localization of cell GO:0051674 202 0.020
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
Human Mouse Rat Fly
organic hydroxy compound metabolic process GO:1901615 115 0.020
regulation of apoptotic process GO:0042981 335 0.020
protein oligomerization GO:0051259 191 0.020
potassium ion transport GO:0006813 97 0.020
negative regulation of developmental process GO:0051093 125 0.020
Worm
cellular macromolecule localization GO:0070727 122 0.019
regulation of immune system process GO:0002682 123 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
cell cycle GO:0007049 101 0.019
chemotaxis GO:0006935 66 0.019
nephron development GO:0072006 22 0.019
regulation of synaptic transmission GO:0050804 141 0.019
organic acid metabolic process GO:0006082 292 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
Human Mouse Rat Fly
growth involved in heart morphogenesis GO:0003241 1 0.019
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.019
positive regulation of cell communication GO:0010647 271 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.019
specification of organ identity GO:0010092 2 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.018
cation transmembrane transport GO:0098655 263 0.018
rna biosynthetic process GO:0032774 380 0.018
regulation of neurogenesis GO:0050767 247 0.018
male gamete generation GO:0048232 99 0.018
Rat
cellular metal ion homeostasis GO:0006875 172 0.018
negative regulation of gamma aminobutyric acid secretion GO:0014053 3 0.018
gonad development GO:0008406 104 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
response to ethanol GO:0045471 162 0.018
oxoacid metabolic process GO:0043436 290 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
negative regulation of transport GO:0051051 136 0.017
neuron differentiation GO:0030182 368 0.017
regulation of transmembrane transport GO:0034762 122 0.017
positive regulation of kinase activity GO:0033674 77 0.017
secretion GO:0046903 307 0.017
response to insulin GO:0032868 133 0.017
regulation of protein transport GO:0051223 68 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
neuron projection development GO:0031175 273 0.017
regulation of nervous system development GO:0051960 264 0.017
positive regulation of transport GO:0051050 245 0.017
cytokine mediated signaling pathway GO:0019221 43 0.017
sex differentiation GO:0007548 113 0.017
positive regulation of protein modification process GO:0031401 142 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
heart development GO:0007507 72 0.016
response to peptide GO:1901652 292 0.016
response to external biotic stimulus GO:0043207 221 0.016
response to glucocorticoid GO:0051384 223 0.016
s shaped body morphogenesis GO:0072050 2 0.016
growth GO:0040007 165 0.016
anterior posterior pattern specification GO:0009952 1 0.016
ovulation cycle process GO:0022602 50 0.016
response to radiation GO:0009314 137 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
single organism catabolic process GO:0044712 283 0.016
calcium ion homeostasis GO:0055074 162 0.016
cell cell signaling GO:0007267 335 0.016
response to peptide hormone GO:0043434 278 0.016
protein heterooligomerization GO:0051291 89 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
regulation of cell migration GO:0030334 128 0.016
cellular response to cytokine stimulus GO:0071345 127 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
protein tetramerization GO:0051262 38 0.015
hormone secretion GO:0046879 115 0.015
reproductive structure development GO:0048608 128 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
cellular ketone metabolic process GO:0042180 51 0.015
multicellular organism growth GO:0035264 1 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
negative regulation of cell death GO:0060548 229 0.015
heart contraction GO:0060047 57 0.015
embryonic pattern specification GO:0009880 1 0.015
organ morphogenesis GO:0009887 75 0.015
protein targeting GO:0006605 61 0.015
response to corticosteroid GO:0031960 235 0.015
macromolecule localization GO:0033036 252 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
Human Mouse Rat Fly
regulation of vasculature development GO:1901342 44 0.015
nucleotide metabolic process GO:0009117 279 0.015
cellular response to metal ion GO:0071248 55 0.015
negative regulation of neuron differentiation GO:0045665 62 0.015
regulation of homeostatic process GO:0032844 101 0.014
cellular response to external stimulus GO:0071496 118 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
organ growth GO:0035265 24 0.014
alkaloid metabolic process GO:0009820 3 0.014
regulation of secretion GO:0051046 224 0.014
endocrine system development GO:0035270 30 0.014
Rat
negative regulation of signal transduction GO:0009968 83 0.014
forebrain development GO:0030900 98 0.014
Rat
regulation of peptide secretion GO:0002791 82 0.014
positive regulation of angiogenesis GO:0045766 28 0.014
cytoplasmic transport GO:0016482 115 0.014
rna metabolic process GO:0016070 406 0.014
cellular carbohydrate metabolic process GO:0044262 72 0.014
response to monosaccharide GO:0034284 159 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
Human Mouse Rat Fly
actin filament based process GO:0030029 86 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
epithelial cell differentiation GO:0030855 71 0.014
Mouse
negative regulation of molecular function GO:0044092 133 0.014
regulation of camp biosynthetic process GO:0030817 38 0.014
response to testosterone GO:0033574 55 0.014
cellular catabolic process GO:0044248 295 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
reproductive behavior GO:0019098 10 0.014
organ regeneration GO:0031100 101 0.014
positive regulation of vasodilation GO:0045909 29 0.014
cellular protein localization GO:0034613 122 0.013
somatic stem cell maintenance GO:0035019 2 0.013
amide transport GO:0042886 105 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
regulation of heterotypic cell cell adhesion GO:0034114 2 0.013
protein localization GO:0008104 191 0.013
tube formation GO:0035148 3 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
cell fate determination GO:0001709 2 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
Human Mouse Rat Fly
glomerulus development GO:0032835 10 0.013
sodium ion transmembrane transport GO:0035725 67 0.013
exogenous drug catabolic process GO:0042738 1 0.013
locomotor rhythm GO:0045475 1 0.013
regulation of neuronal synaptic plasticity GO:0048168 31 0.013
regulation of ion transmembrane transport GO:0034765 121 0.012
regulation of catalytic activity GO:0050790 304 0.012
regulation of cellular localization GO:0060341 263 0.012
mesonephric epithelium development GO:0072163 14 0.012
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.012
positive regulation of lipid kinase activity GO:0090218 2 0.012
response to carbohydrate GO:0009743 183 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
glucose 6 phosphate metabolic process GO:0051156 11 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
response to other organism GO:0051707 220 0.012
regulation of heart contraction GO:0008016 48 0.012
heart growth GO:0060419 20 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
response to alkaloid GO:0043279 132 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
hippocampus development GO:0021766 30 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
cell activation GO:0001775 97 0.012
negative regulation of metabolic process GO:0009892 331 0.012
Human Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.012
embryonic cranial skeleton morphogenesis GO:0048701 2 0.012
respiratory system process GO:0003016 3 0.012
regulation of developmental growth GO:0048638 45 0.011
female pregnancy GO:0007565 122 0.011
divalent inorganic cation transport GO:0072511 134 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
regulation of sodium ion transport GO:0002028 21 0.011
muscle organ development GO:0007517 50 0.011
positive regulation of cell growth GO:0030307 44 0.011
maintenance of location GO:0051235 17 0.011
lipid storage GO:0019915 1 0.011
regulation of camp metabolic process GO:0030814 43 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
muscle tissue development GO:0060537 58 0.011
cellular response to inorganic substance GO:0071241 65 0.011
cell type specific apoptotic process GO:0097285 134 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
nucleic acid templated transcription GO:0097659 379 0.011
organophosphate metabolic process GO:0019637 370 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
Human Mouse Rat Fly
dendrite development GO:0016358 72 0.011
rhythmic behavior GO:0007622 24 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
Human Rat
regulation of catecholamine secretion GO:0050433 32 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
catabolic process GO:0009056 351 0.011
ovulation cycle GO:0042698 67 0.011
regulation of anion transport GO:0044070 43 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
Human Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.010
Human Mouse Rat Fly
inorganic anion transport GO:0015698 41 0.010
embryo development ending in birth or egg hatching GO:0009792 22 0.010
Worm
feeding behavior GO:0007631 53 0.010
neuron development GO:0048666 286 0.010
regulation of organelle organization GO:0033043 80 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
regulation of calcium ion transport GO:0051924 77 0.010
cellular response to camp GO:0071320 26 0.010
glucan metabolic process GO:0044042 23 0.010
positive regulation of cell death GO:0010942 184 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
regulation of actin filament based process GO:0032970 42 0.010
smooth muscle cell proliferation GO:0048659 77 0.010
metanephric tubule morphogenesis GO:0072173 2 0.010
response to growth factor GO:0070848 189 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
protein localization to organelle GO:0033365 57 0.010
epoxygenase p450 pathway GO:0019373 1 0.010
regulation of cardiac muscle cell contraction GO:0086004 11 0.010
immune system process GO:0002376 204 0.010
axon guidance GO:0007411 24 0.010
pallium development GO:0021543 42 0.010

Pou2f3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
long qt syndrome DOID:2843 0 0.121
disease of anatomical entity DOID:7 0 0.021
cardiovascular system disease DOID:1287 0 0.021
kidney disease DOID:557 0 0.017
urinary system disease DOID:18 0 0.017
respiratory system disease DOID:1579 0 0.011
lower respiratory tract disease DOID:0050161 0 0.011
disease of metabolism DOID:0014667 0 0.011
nutrition disease DOID:374 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
obesity DOID:9970 0 0.010
overnutrition DOID:654 0 0.010