Rattus norvegicus

0 known processes

Ppfia4

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4

Ppfia4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.271
enzyme linked receptor protein signaling pathway GO:0007167 116 0.239
cell projection organization GO:0030030 302 0.193
Fly
regulation of phosphate metabolic process GO:0019220 349 0.187
ion transmembrane transport GO:0034220 365 0.154
cation transmembrane transport GO:0098655 263 0.151
positive regulation of phosphorus metabolic process GO:0010562 262 0.114
neuron differentiation GO:0030182 368 0.110
Fly
cell cell signaling GO:0007267 335 0.096
Rat Fly
nitrogen compound transport GO:0071705 229 0.091
regulation of phosphorus metabolic process GO:0051174 349 0.087
cell projection morphogenesis GO:0048858 123 0.083
Fly
macromolecular complex subunit organization GO:0043933 339 0.077
regulation of neuron apoptotic process GO:0043523 83 0.068
regulation of nucleic acid templated transcription GO:1903506 380 0.068
protein complex subunit organization GO:0071822 302 0.066
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.064
regulation of cell development GO:0060284 263 0.064
Fly
neuron death GO:0070997 127 0.064
positive regulation of multicellular organismal process GO:0051240 387 0.059
response to carbohydrate GO:0009743 183 0.058
macromolecular complex assembly GO:0065003 273 0.058
regulation of protein metabolic process GO:0051246 289 0.057
regulation of multicellular organismal development GO:2000026 376 0.057
Fly
regulation of cellular component organization GO:0051128 368 0.056
Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.056
neuron projection development GO:0031175 273 0.054
Fly
positive regulation of molecular function GO:0044093 230 0.053
inorganic cation transmembrane transport GO:0098662 202 0.052
carbohydrate derivative metabolic process GO:1901135 346 0.052
locomotion GO:0040011 237 0.051
Fly
regulation of rna metabolic process GO:0051252 391 0.050
protein complex assembly GO:0006461 263 0.049
intracellular signal transduction GO:0035556 314 0.049
rna metabolic process GO:0016070 406 0.048
signal release GO:0023061 145 0.047
Rat
regulation of nervous system development GO:0051960 264 0.047
Fly
catabolic process GO:0009056 351 0.045
sensory perception of pain GO:0019233 73 0.045
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.045
regulation of signal transduction GO:0009966 318 0.044
response to decreased oxygen levels GO:0036293 237 0.043
central nervous system development GO:0007417 311 0.043
positive regulation of phosphate metabolic process GO:0045937 262 0.042
homeostatic process GO:0042592 331 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.040
action potential GO:0001508 54 0.039
glycosyl compound metabolic process GO:1901657 182 0.039
regulation of transcription dna templated GO:0006355 374 0.039
cation homeostasis GO:0055080 195 0.039
regulation of neuron differentiation GO:0045664 208 0.039
Fly
cellular response to hormone stimulus GO:0032870 247 0.038
metal ion homeostasis GO:0055065 186 0.038
single organism reproductive process GO:0044702 297 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
regulation of cell differentiation GO:0045595 320 0.037
Fly
transcription dna templated GO:0006351 377 0.037
response to inorganic substance GO:0010035 377 0.037
development of primary sexual characteristics GO:0045137 107 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
Fly
chemical homeostasis GO:0048878 292 0.036
regulation of phosphorylation GO:0042325 248 0.036
regulation of neuron death GO:1901214 115 0.036
cellular component movement GO:0006928 248 0.036
Fly
regulation of rna biosynthetic process GO:2001141 381 0.035
response to extracellular stimulus GO:0009991 380 0.035
nucleotide metabolic process GO:0009117 279 0.035
positive regulation of nervous system development GO:0051962 178 0.035
reproductive process GO:0022414 372 0.034
positive regulation of neuron death GO:1901216 43 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
acid secretion GO:0046717 48 0.033
response to peptide hormone GO:0043434 278 0.033
glutamate receptor signaling pathway GO:0007215 43 0.033
secretion GO:0046903 307 0.032
Rat
neuron development GO:0048666 286 0.032
Fly
regulation of hydrolase activity GO:0051336 143 0.032
regulation of synaptic plasticity GO:0048167 70 0.032
Rat
rna biosynthetic process GO:0032774 380 0.031
heart contraction GO:0060047 57 0.031
nucleic acid templated transcription GO:0097659 379 0.030
positive regulation of developmental process GO:0051094 283 0.030
cellular response to oxygen containing compound GO:1901701 386 0.030
organelle organization GO:0006996 266 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
peptide transport GO:0015833 97 0.030
ribonucleoside triphosphate metabolic process GO:0009199 141 0.029
developmental process involved in reproduction GO:0003006 159 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
programmed cell death GO:0012501 392 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
sex differentiation GO:0007548 113 0.028
single organism intracellular transport GO:1902582 166 0.028
organic acid transport GO:0015849 116 0.028
regulation of molecular function GO:0065009 398 0.028
calcium ion transmembrane transport GO:0070588 70 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
positive regulation of neuron projection development GO:0010976 99 0.027
negative regulation of metabolic process GO:0009892 331 0.027
anion transport GO:0006820 178 0.027
amide transport GO:0042886 105 0.027
apoptotic process GO:0006915 381 0.027
hormone transport GO:0009914 121 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
cell type specific apoptotic process GO:0097285 134 0.027
response to metal ion GO:0010038 253 0.027
regulation of cellular localization GO:0060341 263 0.027
positive regulation of response to stimulus GO:0048584 285 0.026
ion homeostasis GO:0050801 212 0.026
negative regulation of signaling GO:0023057 157 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.026
blood circulation GO:0008015 183 0.026
behavior GO:0007610 205 0.025
Fly
circulatory system process GO:0003013 183 0.025
positive regulation of cell projection organization GO:0031346 111 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
positive regulation of cell communication GO:0010647 271 0.025
nucleoside catabolic process GO:0009164 126 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
carboxylic acid transport GO:0046942 115 0.025
reproduction GO:0000003 245 0.025
negative regulation of gene expression GO:0010629 199 0.025
response to glucocorticoid GO:0051384 223 0.024
response to nutrient levels GO:0031667 370 0.024
purine ribonucleotide catabolic process GO:0009154 136 0.024
cellular component biogenesis GO:0044085 368 0.024
Fly
cellular ion homeostasis GO:0006873 184 0.024
protein oligomerization GO:0051259 191 0.024
purine nucleoside catabolic process GO:0006152 124 0.023
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
regulation of cell projection organization GO:0031344 175 0.023
Fly
protein phosphorylation GO:0006468 345 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
regulation of metal ion transport GO:0010959 118 0.023
multicellular organism reproduction GO:0032504 233 0.023
regulation of system process GO:0044057 208 0.023
head development GO:0060322 247 0.022
hormone secretion GO:0046879 115 0.022
protein autophosphorylation GO:0046777 66 0.022
growth GO:0040007 165 0.022
Fly
synaptic transmission GO:0007268 235 0.022
Rat Fly
positive regulation of signal transduction GO:0009967 175 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
nucleoside triphosphate metabolic process GO:0009141 144 0.022
positive regulation of cell development GO:0010720 176 0.022
negative regulation of secretion GO:0051048 82 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
positive regulation of protein modification process GO:0031401 142 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
cellular chemical homeostasis GO:0055082 247 0.021
cell morphogenesis GO:0000902 142 0.021
Fly
positive regulation of cell death GO:0010942 184 0.021
divalent inorganic cation transport GO:0072511 134 0.021
regulation of secretion GO:0051046 224 0.020
heterocycle catabolic process GO:0046700 167 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
multi organism reproductive process GO:0044703 262 0.020
protein complex biogenesis GO:0070271 263 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
cellular homeostasis GO:0019725 252 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.019
aromatic compound catabolic process GO:0019439 168 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
metal ion transport GO:0030001 289 0.019
neurotransmitter secretion GO:0007269 33 0.019
Rat
regulation of neurogenesis GO:0050767 247 0.019
Fly
muscle organ morphogenesis GO:0048644 1 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
regulation of apoptotic process GO:0042981 335 0.019
neurological system process GO:0050877 219 0.019
actin filament based process GO:0030029 86 0.019
tissue development GO:0009888 252 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
response to corticosteroid GO:0031960 235 0.019
male gonad development GO:0008584 59 0.018
neuromuscular process GO:0050905 2 0.018
reproductive system development GO:0061458 128 0.018
response to hexose GO:0009746 144 0.018
cellular response to stress GO:0033554 269 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
cellular cation homeostasis GO:0030003 180 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of hydrolase activity GO:0051345 86 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
amino acid transport GO:0006865 70 0.018
regulation of mapk cascade GO:0043408 116 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
cellular macromolecule localization GO:0070727 122 0.018
regulation of catalytic activity GO:0050790 304 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
negative regulation of neuron death GO:1901215 69 0.018
response to monosaccharide GO:0034284 159 0.018
response to hypoxia GO:0001666 231 0.018
cellular response to glucocorticoid stimulus GO:0071385 68 0.017
positive regulation of calcium ion transport GO:0051928 36 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
response to nutrient GO:0007584 248 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
male sex differentiation GO:0046661 64 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
positive regulation of gene expression GO:0010628 244 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
neural crest cell development GO:0014032 2 0.017
nucleoside monophosphate catabolic process GO:0009125 56 0.017
cytoskeleton organization GO:0007010 111 0.017
purine nucleoside triphosphate catabolic process GO:0009146 122 0.017
regulation of receptor recycling GO:0001919 6 0.017
synapse organization GO:0050808 46 0.017
Fly
negative regulation of cell death GO:0060548 229 0.017
positive regulation of biosynthetic process GO:0009891 319 0.016
regulation of growth GO:0040008 105 0.016
Fly
macromolecule localization GO:0033036 252 0.016
regulation of exocytosis GO:0017157 37 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
divalent metal ion transport GO:0070838 132 0.016
single organism organelle organization GO:1902589 180 0.016
calcium mediated signaling GO:0019722 23 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
Fly
stress activated protein kinase signaling cascade GO:0031098 37 0.016
positive regulation of neuron apoptotic process GO:0043525 33 0.016
single organism membrane organization GO:0044802 74 0.015
cytosolic calcium ion transport GO:0060401 39 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
membrane organization GO:0061024 94 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
regulation of axonogenesis GO:0050770 37 0.015
Fly
negative regulation of cell development GO:0010721 82 0.015
amine metabolic process GO:0009308 38 0.015
proteolysis GO:0006508 175 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
ras protein signal transduction GO:0007265 29 0.015
cellular protein localization GO:0034613 122 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
regulation of small gtpase mediated signal transduction GO:0051056 48 0.015
negative regulation of transport GO:0051051 136 0.014
gonad development GO:0008406 104 0.014
b cell differentiation GO:0030183 2 0.014
insulin secretion GO:0030073 69 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
multi multicellular organism process GO:0044706 138 0.014
cell growth GO:0016049 104 0.014
Fly
negative regulation of cellular metabolic process GO:0031324 281 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
cellular amine metabolic process GO:0044106 38 0.014
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.014
purine containing compound metabolic process GO:0072521 253 0.014
organophosphate metabolic process GO:0019637 370 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
regulation of secretion by cell GO:1903530 208 0.014
regulation of neuron projection development GO:0010975 161 0.014
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
organic anion transport GO:0015711 132 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
developmental growth GO:0048589 100 0.014
Fly
regulation of peptide secretion GO:0002791 82 0.014
response to temperature stimulus GO:0009266 94 0.014
cellular ketone metabolic process GO:0042180 51 0.014
muscle structure development GO:0061061 87 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
cellular catabolic process GO:0044248 295 0.014
protein polymerization GO:0051258 22 0.013
clustering of voltage gated potassium channels GO:0045163 1 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of peptide transport GO:0090087 87 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
neuron projection morphogenesis GO:0048812 122 0.013
Fly
intracellular protein transport GO:0006886 79 0.013
exocytosis GO:0006887 60 0.013
transmission of nerve impulse GO:0019226 42 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
response to oxygen levels GO:0070482 265 0.013
muscle system process GO:0003012 115 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
nucleoside metabolic process GO:0009116 179 0.013
regulation of transmembrane transporter activity GO:0022898 49 0.013
establishment of protein localization GO:0045184 141 0.013
protein localization GO:0008104 191 0.013
regulation of cell proliferation GO:0042127 359 0.013
response to peptide GO:1901652 292 0.013
spermatogenesis GO:0007283 99 0.013
regulation of glucose transport GO:0010827 18 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
epithelium development GO:0060429 96 0.013
muscle contraction GO:0006936 88 0.013
peptidyl amino acid modification GO:0018193 126 0.013
regulation of transmembrane transport GO:0034762 122 0.013
regulation of ion transmembrane transport GO:0034765 121 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
male gamete generation GO:0048232 99 0.012
calcium ion homeostasis GO:0055074 162 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.012
single organism catabolic process GO:0044712 283 0.012
positive regulation of cardiac muscle contraction GO:0060452 4 0.012
single organism behavior GO:0044708 130 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
intracellular transport GO:0046907 185 0.012
gliogenesis GO:0042063 93 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
cellular component assembly GO:0022607 360 0.012
Fly
salivary gland morphogenesis GO:0007435 1 0.012
neuronal ion channel clustering GO:0045161 3 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
aging GO:0007568 241 0.011
calcium ion import GO:0070509 22 0.011
response to estrogen GO:0043627 232 0.011
multicellular organismal signaling GO:0035637 44 0.011
negative regulation of cell communication GO:0010648 158 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
regulation of protein modification process GO:0031399 194 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
regulation of ion transport GO:0043269 245 0.011
regeneration GO:0031099 163 0.011
purine containing compound catabolic process GO:0072523 138 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
calcium ion transport GO:0006816 131 0.011
peptide hormone secretion GO:0030072 84 0.011
cell part morphogenesis GO:0032990 123 0.011
Fly
carboxylic acid metabolic process GO:0019752 289 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
receptor recycling GO:0001881 6 0.011
brain development GO:0007420 247 0.011
organophosphate catabolic process GO:0046434 148 0.011
atp metabolic process GO:0046034 72 0.011
organic substance catabolic process GO:1901575 316 0.011
autophagic cell death GO:0048102 4 0.011
inflammatory response GO:0006954 150 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
defecation GO:0030421 1 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
spindle organization GO:0007051 2 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
response to cytokine GO:0034097 215 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
Fly
developmental maturation GO:0021700 25 0.010
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.010
chemosensory behavior GO:0007635 2 0.010
positive regulation of growth GO:0045927 55 0.010
regulation of anatomical structure size GO:0090066 135 0.010
Fly

Ppfia4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.104
musculoskeletal system disease DOID:17 0 0.104
connective tissue disease DOID:65 0 0.028
muscular disease DOID:0080000 0 0.028
muscle tissue disease DOID:66 0 0.028
bone disease DOID:0080001 0 0.024
nervous system disease DOID:863 0 0.019
bone development disease DOID:0080006 0 0.018
myopathy DOID:423 0 0.017
cardiovascular system disease DOID:1287 0 0.014