Rattus norvegicus

0 known processes

Ppm1b

protein phosphatase 1B, magnesium dependent, beta isoform

(Aliases: Pp2c2)

Ppm1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of proteasomal protein catabolic process GO:0061136 4 0.299
macromolecule catabolic process GO:0009057 58 0.135
single organism biosynthetic process GO:0044711 342 0.134
intracellular transport GO:0046907 185 0.114
Human
organelle organization GO:0006996 266 0.112
protein modification by small protein conjugation or removal GO:0070647 35 0.109
catabolic process GO:0009056 351 0.104
intracellular signal transduction GO:0035556 314 0.102
Human
macromolecular complex subunit organization GO:0043933 339 0.097
dephosphorylation GO:0016311 98 0.093
Human
metaphase anaphase transition of cell cycle GO:0044784 1 0.090
transcription dna templated GO:0006351 377 0.088
cellular catabolic process GO:0044248 295 0.087
protein catabolic process GO:0030163 30 0.085
regulation of catabolic process GO:0009894 113 0.083
single organism carbohydrate metabolic process GO:0044723 118 0.082
regulation of sister chromatid segregation GO:0033045 1 0.073
cellular homeostasis GO:0019725 252 0.072
protein modification by small protein conjugation GO:0032446 31 0.071
regulation of intracellular signal transduction GO:1902531 218 0.070
Human
organic substance catabolic process GO:1901575 316 0.070
nucleoside phosphate metabolic process GO:0006753 283 0.067
mapk cascade GO:0000165 140 0.066
positive regulation of cell communication GO:0010647 271 0.066
proteolysis GO:0006508 175 0.066
organophosphate metabolic process GO:0019637 370 0.065
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.065
polysaccharide metabolic process GO:0005976 25 0.064
cellular response to stress GO:0033554 269 0.064
regulation of phosphate metabolic process GO:0019220 349 0.059
carbohydrate metabolic process GO:0005975 130 0.059
homeostatic process GO:0042592 331 0.058
glycogen metabolic process GO:0005977 23 0.058
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.057
protein complex subunit organization GO:0071822 302 0.056
reproductive process GO:0022414 372 0.056
programmed cell death GO:0012501 392 0.053
metaphase plate congression GO:0051310 1 0.052
regulation of phosphorylation GO:0042325 248 0.052
regulation of phosphorus metabolic process GO:0051174 349 0.052
regulation of signal transduction GO:0009966 318 0.051
Human
positive regulation of signaling GO:0023056 270 0.049
negative regulation of signaling GO:0023057 157 0.048
Human
vesicle mediated transport GO:0016192 181 0.048
behavior GO:0007610 205 0.047
nucleic acid templated transcription GO:0097659 379 0.047
regulation of mitotic sister chromatid separation GO:0010965 1 0.045
negative regulation of cell communication GO:0010648 158 0.044
Human
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.044
organic acid metabolic process GO:0006082 292 0.044
single organism organelle organization GO:1902589 180 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.043
macromolecular complex assembly GO:0065003 273 0.043
cell cycle GO:0007049 101 0.043
regulation of cellular component organization GO:0051128 368 0.042
mitotic spindle organization GO:0007052 2 0.041
modification dependent macromolecule catabolic process GO:0043632 14 0.041
inorganic ion transmembrane transport GO:0098660 229 0.041
regulation of protein metabolic process GO:0051246 289 0.041
metal ion transport GO:0030001 289 0.041
cell cycle process GO:0022402 57 0.039
small gtpase mediated signal transduction GO:0007264 36 0.039
negative regulation of transport GO:0051051 136 0.039
Human
energy reserve metabolic process GO:0006112 25 0.039
ion transmembrane transport GO:0034220 365 0.039
cellular chemical homeostasis GO:0055082 247 0.039
regulation of programmed cell death GO:0043067 341 0.039
ras protein signal transduction GO:0007265 29 0.037
regulation of chromosome segregation GO:0051983 1 0.037
calcium ion transport GO:0006816 131 0.037
negative regulation of phosphate metabolic process GO:0045936 80 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
glucan metabolic process GO:0044042 23 0.036
regulation of rna biosynthetic process GO:2001141 381 0.036
spindle organization GO:0007051 2 0.035
regulation of protein catabolic process GO:0042176 16 0.035
cellular component biogenesis GO:0044085 368 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
chromosome segregation GO:0007059 2 0.034
protein ubiquitination GO:0016567 28 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
mitotic sister chromatid separation GO:0051306 1 0.033
negative regulation of cell death GO:0060548 229 0.033
response to hypoxia GO:0001666 231 0.033
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
response to light stimulus GO:0009416 52 0.032
negative regulation of apoptotic process GO:0043066 181 0.032
peptide transport GO:0015833 97 0.031
Human
regulation of cell cycle GO:0051726 73 0.030
cytoskeleton organization GO:0007010 111 0.030
cellular carbohydrate metabolic process GO:0044262 72 0.030
circulatory system development GO:0072359 134 0.029
carbohydrate homeostasis GO:0033500 75 0.029
regulation of cell differentiation GO:0045595 320 0.029
regulation of secretion GO:0051046 224 0.029
regulation of protein targeting GO:1903533 28 0.029
Human
protein dephosphorylation GO:0006470 38 0.029
Human
heterocycle catabolic process GO:0046700 167 0.028
cellular protein localization GO:0034613 122 0.028
Human
multi organism reproductive process GO:0044703 262 0.028
muscle system process GO:0003012 115 0.028
regulation of catalytic activity GO:0050790 304 0.028
positive regulation of response to stimulus GO:0048584 285 0.028
positive regulation of catabolic process GO:0009896 78 0.028
protein complex biogenesis GO:0070271 263 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.027
negative regulation of metabolic process GO:0009892 331 0.027
oxoacid metabolic process GO:0043436 290 0.027
negative regulation of intracellular signal transduction GO:1902532 38 0.027
Human
regulation of molecular function GO:0065009 398 0.027
ribonucleoside metabolic process GO:0009119 174 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
ribonucleoside monophosphate metabolic process GO:0009161 88 0.026
single organism catabolic process GO:0044712 283 0.026
regulation of peptide transport GO:0090087 87 0.026
Human
response to decreased oxygen levels GO:0036293 237 0.026
amide transport GO:0042886 105 0.026
Human
multicellular organism reproduction GO:0032504 233 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
cell cell signaling GO:0007267 335 0.025
cellular macromolecule localization GO:0070727 122 0.025
Human
regulation of proteolysis GO:0030162 66 0.025
ribonucleotide metabolic process GO:0009259 231 0.024
negative regulation of cell cycle phase transition GO:1901988 4 0.024
regulation of apoptotic process GO:0042981 335 0.024
regulation of mitotic sister chromatid segregation GO:0033047 1 0.024
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.024
cellular component assembly GO:0022607 360 0.024
response to oxygen levels GO:0070482 265 0.024
glucose homeostasis GO:0042593 75 0.024
single organism intracellular transport GO:1902582 166 0.024
Human
ion homeostasis GO:0050801 212 0.023
regulation of mapk cascade GO:0043408 116 0.023
establishment of chromosome localization GO:0051303 1 0.023
nucleoside monophosphate metabolic process GO:0009123 93 0.023
regulation of protein modification process GO:0031399 194 0.023
regulation of hydrolase activity GO:0051336 143 0.023
negative regulation of response to stimulus GO:0048585 155 0.022
Human
sister chromatid segregation GO:0000819 1 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.022
regulation of cellular localization GO:0060341 263 0.022
Human
negative regulation of programmed cell death GO:0043069 183 0.022
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.022
regulation of canonical wnt signaling pathway GO:0060828 4 0.022
coenzyme metabolic process GO:0006732 86 0.022
regulation of muscle system process GO:0090257 79 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
organophosphate catabolic process GO:0046434 148 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
mitotic sister chromatid segregation GO:0000070 1 0.021
chemical homeostasis GO:0048878 292 0.021
protein complex assembly GO:0006461 263 0.021
chromosome separation GO:0051304 1 0.021
chromatin organization GO:0006325 34 0.021
cognition GO:0050890 92 0.021
modification dependent protein catabolic process GO:0019941 14 0.021
transmembrane transport GO:0055085 412 0.020
response to inorganic substance GO:0010035 377 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
positive regulation of signal transduction GO:0009967 175 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
cellular glucan metabolic process GO:0006073 23 0.020
lipid metabolic process GO:0006629 283 0.020
response to monosaccharide GO:0034284 159 0.020
peptide hormone secretion GO:0030072 84 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.020
tissue development GO:0009888 252 0.020
single organism behavior GO:0044708 130 0.020
divalent metal ion transport GO:0070838 132 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
protein phosphorylation GO:0006468 345 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
cation transmembrane transport GO:0098655 263 0.019
response to carbohydrate GO:0009743 183 0.019
nitrogen compound transport GO:0071705 229 0.019
Human
positive regulation of locomotion GO:0040017 102 0.019
cellular protein catabolic process GO:0044257 19 0.019
nucleoside catabolic process GO:0009164 126 0.019
neuron differentiation GO:0030182 368 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
reproduction GO:0000003 245 0.018
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.018
blood circulation GO:0008015 183 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
regulation of cellular component movement GO:0051270 150 0.018
multi multicellular organism process GO:0044706 138 0.018
neuron development GO:0048666 286 0.018
macromolecule localization GO:0033036 252 0.018
Human
glycosyl compound catabolic process GO:1901658 126 0.018
peptide secretion GO:0002790 86 0.018
cellular response to hexose stimulus GO:0071331 65 0.017
chromosome organization GO:0051276 36 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
learning or memory GO:0007611 90 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
neuron projection development GO:0031175 273 0.017
neurological system process GO:0050877 219 0.017
protein localization GO:0008104 191 0.017
Human
dna metabolic process GO:0006259 96 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of neuron projection development GO:0010975 161 0.017
single organism reproductive process GO:0044702 297 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
calcium ion homeostasis GO:0055074 162 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
negative regulation of molecular function GO:0044092 133 0.017
regulation of cell development GO:0060284 263 0.017
response to cytokine GO:0034097 215 0.017
regulation of anatomical structure size GO:0090066 135 0.017
regulation of secretion by cell GO:1903530 208 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
atp metabolic process GO:0046034 72 0.017
response to glucose GO:0009749 136 0.016
cellular ion homeostasis GO:0006873 184 0.016
cellular polysaccharide metabolic process GO:0044264 23 0.016
circulatory system process GO:0003013 183 0.016
secretion GO:0046903 307 0.016
sleep GO:0030431 30 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
regulation of ion transport GO:0043269 245 0.016
regulation of homotypic cell cell adhesion GO:0034110 4 0.016
cell cycle checkpoint GO:0000075 2 0.016
cellular amine metabolic process GO:0044106 38 0.016
regulation of homeostatic process GO:0032844 101 0.016
heart development GO:0007507 72 0.015
response to peptide GO:1901652 292 0.015
regulation of peptide secretion GO:0002791 82 0.015
response to external biotic stimulus GO:0043207 221 0.015
Human
gastrulation GO:0007369 2 0.015
response to other organism GO:0051707 220 0.015
Human
erk1 and erk2 cascade GO:0070371 48 0.015
response to hexose GO:0009746 144 0.015
chemosensory behavior GO:0007635 2 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
regulation of immune system process GO:0002682 123 0.015
Human
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.015
ubiquitin dependent protein catabolic process GO:0006511 14 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
protein polyubiquitination GO:0000209 3 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.014
response to radiation GO:0009314 137 0.014
memory GO:0007613 54 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
protein homooligomerization GO:0051260 91 0.014
nucleotide metabolic process GO:0009117 279 0.014
small molecule biosynthetic process GO:0044283 124 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
cytoplasmic transport GO:0016482 115 0.014
Human
insulin secretion GO:0030073 69 0.014
rna biosynthetic process GO:0032774 380 0.014
regulation of cell cycle process GO:0010564 31 0.014
cellular polysaccharide biosynthetic process GO:0033692 15 0.014
response to reactive oxygen species GO:0000302 120 0.014
positive regulation of molecular function GO:0044093 230 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
rhythmic process GO:0048511 156 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
double strand break repair GO:0006302 1 0.014
cellular response to carbohydrate stimulus GO:0071322 72 0.013
regulation of cell projection organization GO:0031344 175 0.013
hormone secretion GO:0046879 115 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
response to peptide hormone GO:0043434 278 0.013
regulation of response to stress GO:0080134 126 0.013
Human
cardiovascular system development GO:0072358 134 0.013
cofactor metabolic process GO:0051186 95 0.013
locomotion GO:0040011 237 0.013
aging GO:0007568 241 0.013
cell projection organization GO:0030030 302 0.013
microtubule cytoskeleton organization GO:0000226 25 0.013
positive regulation of immune system process GO:0002684 90 0.013
response to increased oxygen levels GO:0036296 45 0.013
cation transport GO:0006812 382 0.013
positive regulation of developmental process GO:0051094 283 0.013
regulation of nucleocytoplasmic transport GO:0046822 28 0.013
Human
purine ribonucleotide metabolic process GO:0009150 227 0.013
mitotic cell cycle process GO:1903047 35 0.013
regulation of membrane potential GO:0042391 110 0.013
cellular response to drug GO:0035690 30 0.013
dna integrity checkpoint GO:0031570 2 0.013
secretion by cell GO:0032940 248 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
signal release GO:0023061 145 0.013
positive regulation of protein modification process GO:0031401 142 0.012
protein localization to chromosome GO:0034502 1 0.012
microtubule organizing center organization GO:0031023 1 0.012
jnk cascade GO:0007254 28 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
mitotic dna damage checkpoint GO:0044773 1 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
response to toxic substance GO:0009636 133 0.012
regulation of cell cycle phase transition GO:1901987 12 0.012
positive regulation of ion transport GO:0043270 94 0.012
female pregnancy GO:0007565 122 0.012
second messenger mediated signaling GO:0019932 51 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
cell growth GO:0016049 104 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
regulation of cellular protein catabolic process GO:1903362 7 0.012
adult locomotory behavior GO:0008344 4 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
negative regulation of protein phosphorylation GO:0001933 44 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
negative regulation of stress activated mapk cascade GO:0032873 4 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
cellular ketone metabolic process GO:0042180 51 0.012
chromosome localization GO:0050000 1 0.012
mitotic cell cycle GO:0000278 49 0.012
epithelium development GO:0060429 96 0.012
divalent inorganic cation transport GO:0072511 134 0.012
detection of stimulus GO:0051606 24 0.011
embryo development GO:0009790 49 0.011
regulation of nervous system development GO:0051960 264 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
mitotic cell cycle phase transition GO:0044772 20 0.011
circadian regulation of gene expression GO:0032922 3 0.011
regulation of rna metabolic process GO:0051252 391 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
regulation of transcription dna templated GO:0006355 374 0.011
amine metabolic process GO:0009308 38 0.011
cell cycle phase transition GO:0044770 21 0.011
anterior posterior pattern specification GO:0009952 1 0.011
nucleotide catabolic process GO:0009166 139 0.011
cellular glucose homeostasis GO:0001678 66 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
ncrna processing GO:0034470 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
regulation of cytokine production GO:0001817 56 0.011
Human
centrosome organization GO:0051297 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
response to oxidative stress GO:0006979 186 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of chromosome organization GO:0033044 9 0.011
negative regulation of hormone secretion GO:0046888 46 0.011
protein k63 linked ubiquitination GO:0070534 2 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
purine containing compound catabolic process GO:0072523 138 0.011
positive regulation of cell development GO:0010720 176 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
regulation of hormone levels GO:0010817 187 0.011
mitotic cell cycle checkpoint GO:0007093 1 0.011
regulation of neurogenesis GO:0050767 247 0.011
negative regulation of signal transduction GO:0009968 83 0.011
Human
positive regulation of programmed cell death GO:0043068 157 0.011
response to estradiol GO:0032355 164 0.011
aromatic compound catabolic process GO:0019439 168 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
response to metal ion GO:0010038 253 0.010
synaptic transmission GO:0007268 235 0.010
ribonucleoside monophosphate catabolic process GO:0009158 55 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
establishment of protein localization GO:0045184 141 0.010
Human
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
response to amine GO:0014075 46 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
olfactory behavior GO:0042048 2 0.010
positive regulation of cell migration GO:0030335 96 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
regulation of transporter activity GO:0032409 50 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
glycogen biosynthetic process GO:0005978 15 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.010
positive regulation of biosynthetic process GO:0009891 319 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010

Ppm1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.044
disease of anatomical entity DOID:7 0 0.044
eye and adnexa disease DOID:1492 0 0.044
nervous system disease DOID:863 0 0.044
eye disease DOID:5614 0 0.044
retinal disease DOID:5679 0 0.038
retinal degeneration DOID:8466 0 0.021
retinitis pigmentosa DOID:10584 0 0.015