Rattus norvegicus

0 known processes

Ppm1g

protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform

Ppm1g biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.366
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.283
negative regulation of macromolecule metabolic process GO:0010605 260 0.245
nucleic acid templated transcription GO:0097659 379 0.234
negative regulation of rna metabolic process GO:0051253 123 0.230
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.196
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.182
rna biosynthetic process GO:0032774 380 0.180
negative regulation of metabolic process GO:0009892 331 0.169
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.167
transcription dna templated GO:0006351 377 0.157
positive regulation of transcription factor import into nucleus GO:0042993 4 0.155
negative regulation of cellular metabolic process GO:0031324 281 0.153
regulation of transcription dna templated GO:0006355 374 0.146
rna metabolic process GO:0016070 406 0.145
organelle organization GO:0006996 266 0.144
alternative mrna splicing via spliceosome GO:0000380 4 0.136
macromolecule localization GO:0033036 252 0.131
regulation of nucleic acid templated transcription GO:1903506 380 0.127
protein complex subunit organization GO:0071822 302 0.127
negative regulation of cellular biosynthetic process GO:0031327 161 0.126
regulation of rna biosynthetic process GO:2001141 381 0.122
negative regulation of biosynthetic process GO:0009890 168 0.117
negative regulation of rna splicing GO:0033119 3 0.116
negative regulation of rna biosynthetic process GO:1902679 118 0.112
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.111
positive regulation of transcription dna templated GO:0045893 197 0.104
positive regulation of rna biosynthetic process GO:1902680 197 0.103
rhythmic process GO:0048511 156 0.092
positive regulation of cellular biosynthetic process GO:0031328 295 0.091
regulation of cellular protein metabolic process GO:0032268 267 0.089
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.086
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.085
positive regulation of biosynthetic process GO:0009891 319 0.085
transcription from rna polymerase ii promoter GO:0006366 252 0.085
negative regulation of transcription dna templated GO:0045892 116 0.081
negative regulation of nucleic acid templated transcription GO:1903507 117 0.072
positive regulation of gene expression GO:0010628 244 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.067
regulation of protein metabolic process GO:0051246 289 0.067
anatomical structure morphogenesis GO:0009653 298 0.066
positive regulation of nucleic acid templated transcription GO:1903508 197 0.065
spindle organization GO:0007051 2 0.065
microtubule based process GO:0007017 36 0.064
regulation of organelle organization GO:0033043 80 0.062
single organism reproductive process GO:0044702 297 0.061
positive regulation of rna metabolic process GO:0051254 203 0.056
single organism organelle organization GO:1902589 180 0.053
regulation of cellular localization GO:0060341 263 0.052
cell cycle GO:0007049 101 0.051
negative regulation of gene expression GO:0010629 199 0.051
regulation of mrna splicing via spliceosome GO:0048024 3 0.047
cellular component assembly GO:0022607 360 0.046
cytoskeleton organization GO:0007010 111 0.046
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.046
cell morphogenesis GO:0000902 142 0.046
immune system process GO:0002376 204 0.045
neuron projection development GO:0031175 273 0.045
regulation of cell proliferation GO:0042127 359 0.045
protein phosphorylation GO:0006468 345 0.044
innate immune response GO:0045087 35 0.043
chromosome organization GO:0051276 36 0.042
nucleoside metabolic process GO:0009116 179 0.042
regulation of canonical wnt signaling pathway GO:0060828 4 0.041
reproductive process GO:0022414 372 0.040
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.039
nitrogen compound transport GO:0071705 229 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.037
cellular component movement GO:0006928 248 0.037
organophosphate metabolic process GO:0019637 370 0.036
glycosyl compound metabolic process GO:1901657 182 0.036
chromatin modification GO:0016568 33 0.036
neuron differentiation GO:0030182 368 0.035
organophosphate biosynthetic process GO:0090407 143 0.034
nucleotide metabolic process GO:0009117 279 0.034
lipid localization GO:0010876 62 0.033
protein complex biogenesis GO:0070271 263 0.033
ribonucleotide metabolic process GO:0009259 231 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.031
locomotion GO:0040011 237 0.030
dna modification GO:0006304 12 0.030
behavior GO:0007610 205 0.030
regulation of protein localization GO:0032880 81 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
intracellular transport GO:0046907 185 0.029
amine metabolic process GO:0009308 38 0.029
dna metabolic process GO:0006259 96 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
purine ribonucleoside metabolic process GO:0046128 168 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
cellular amine metabolic process GO:0044106 38 0.027
negative regulation of developmental process GO:0051093 125 0.027
purine containing compound metabolic process GO:0072521 253 0.026
single organism biosynthetic process GO:0044711 342 0.026
reproductive structure development GO:0048608 128 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
negative regulation of mrna splicing via spliceosome GO:0048025 2 0.025
multi organism reproductive process GO:0044703 262 0.025
protein localization GO:0008104 191 0.024
reproduction GO:0000003 245 0.024
negative regulation of protein metabolic process GO:0051248 114 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
purine nucleotide metabolic process GO:0006163 229 0.022
reproductive system development GO:0061458 128 0.022
chromatin organization GO:0006325 34 0.022
regulation of response to stress GO:0080134 126 0.022
neuron development GO:0048666 286 0.022
cytoplasmic transport GO:0016482 115 0.022
tissue development GO:0009888 252 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
cellular protein localization GO:0034613 122 0.022
cellular component morphogenesis GO:0032989 155 0.021
fertilization GO:0009566 3 0.021
regulation of proteasomal protein catabolic process GO:0061136 4 0.021
axis specification GO:0009798 4 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
secretion GO:0046903 307 0.021
regulation of protein import into nucleus GO:0042306 24 0.021
immune response GO:0006955 104 0.021
cellular catabolic process GO:0044248 295 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
regulation of viral transcription GO:0046782 2 0.020
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.020
cell projection organization GO:0030030 302 0.019
female pregnancy GO:0007565 122 0.019
regulation of protein modification process GO:0031399 194 0.019
signal release GO:0023061 145 0.019
mitochondrial rna metabolic process GO:0000959 1 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.019
aging GO:0007568 241 0.018
response to peptide hormone GO:0043434 278 0.018
regulation of cellular component organization GO:0051128 368 0.018
regulation of cellular response to stress GO:0080135 49 0.018
regulation of meiotic cell cycle GO:0051445 3 0.018
response to carbohydrate GO:0009743 183 0.018
protein targeting GO:0006605 61 0.018
negative regulation of cell differentiation GO:0045596 99 0.017
organic acid metabolic process GO:0006082 292 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of cell differentiation GO:0045595 320 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
cellular macromolecule localization GO:0070727 122 0.017
cellular response to stress GO:0033554 269 0.017
regulation of catalytic activity GO:0050790 304 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
defense response GO:0006952 194 0.017
regulation of protein targeting GO:1903533 28 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
protein oligomerization GO:0051259 191 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
neurological system process GO:0050877 219 0.015
cellular component biogenesis GO:0044085 368 0.015
embryonic pattern specification GO:0009880 1 0.015
embryo development GO:0009790 49 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
regulation of fat cell differentiation GO:0045598 3 0.015
cellular macromolecular complex assembly GO:0034622 58 0.015
positive regulation of developmental process GO:0051094 283 0.015
nucleocytoplasmic transport GO:0006913 48 0.015
microtubule cytoskeleton organization GO:0000226 25 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.014
protein autophosphorylation GO:0046777 66 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
sodium ion transport GO:0006814 82 0.014
circulatory system development GO:0072359 134 0.014
positive regulation of cytoplasmic transport GO:1903651 32 0.014
multicellular organism reproduction GO:0032504 233 0.014
cell fate determination GO:0001709 2 0.014
response to growth factor GO:0070848 189 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
oxoacid metabolic process GO:0043436 290 0.014
positive regulation of phosphorylation GO:0042327 177 0.013
programmed cell death GO:0012501 392 0.013
axis elongation GO:0003401 2 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of gene expression epigenetic GO:0040029 10 0.013
regulation of nucleocytoplasmic transport GO:0046822 28 0.013
chromatin assembly or disassembly GO:0006333 1 0.013
secretion by cell GO:0032940 248 0.013
positive regulation of protein modification process GO:0031401 142 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
protein complex assembly GO:0006461 263 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
protein localization to organelle GO:0033365 57 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
response to peptide GO:1901652 292 0.012
viral transcription GO:0019083 2 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
heterocycle catabolic process GO:0046700 167 0.012
cell cycle process GO:0022402 57 0.012
peptidyl amino acid modification GO:0018193 126 0.012
regulation of hormone levels GO:0010817 187 0.012
neuron projection morphogenesis GO:0048812 122 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
translation GO:0006412 35 0.012
cellular chemical homeostasis GO:0055082 247 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
embryonic skeletal system development GO:0048706 3 0.012
homeostatic process GO:0042592 331 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
stress activated mapk cascade GO:0051403 35 0.012
chemical homeostasis GO:0048878 292 0.012
organic substance catabolic process GO:1901575 316 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
dicarboxylic acid metabolic process GO:0043648 42 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
cellular ketone metabolic process GO:0042180 51 0.011
positive regulation of catabolic process GO:0009896 78 0.011
inflammatory response GO:0006954 150 0.011
cation transport GO:0006812 382 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
male gamete generation GO:0048232 99 0.011
regulation of molecular function GO:0065009 398 0.011
purine containing compound catabolic process GO:0072523 138 0.011
regulation of neurogenesis GO:0050767 247 0.011
apoptotic process GO:0006915 381 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
establishment of protein localization GO:0045184 141 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
macromolecule methylation GO:0043414 16 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
catabolic process GO:0009056 351 0.011
macromolecular complex assembly GO:0065003 273 0.011
multi multicellular organism process GO:0044706 138 0.011
epithelium development GO:0060429 96 0.011
cell motility GO:0048870 202 0.011
positive regulation of molecular function GO:0044093 230 0.011
chromatin remodeling GO:0006338 3 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
calcium ion homeostasis GO:0055074 162 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
localization of cell GO:0051674 202 0.010
neural crest cell differentiation GO:0014033 2 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
axonogenesis GO:0007409 71 0.010
multicellular organismal signaling GO:0035637 44 0.010
regulation of cytoskeleton organization GO:0051493 49 0.010
embryonic placenta development GO:0001892 1 0.010
response to monosaccharide GO:0034284 159 0.010
negative regulation of cell communication GO:0010648 158 0.010
intracellular protein transport GO:0006886 79 0.010
cell cycle checkpoint GO:0000075 2 0.010
cellular homeostasis GO:0019725 252 0.010
response to extracellular stimulus GO:0009991 380 0.010
regulation of cell motility GO:2000145 131 0.010

Ppm1g disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
sensory system disease DOID:0050155 0 0.015
myopathy DOID:423 0 0.015
muscular disease DOID:0080000 0 0.015
heart disease DOID:114 0 0.015
cardiomyopathy DOID:0050700 0 0.015
dilated cardiomyopathy DOID:12930 0 0.015
intrinsic cardiomyopathy DOID:0060036 0 0.015
cardiovascular system disease DOID:1287 0 0.015
musculoskeletal system disease DOID:17 0 0.015
muscle tissue disease DOID:66 0 0.015
neuropathy DOID:870 0 0.014