|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.574
|
Human |
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.484
|
Human |
|
|
organelle organization
|
GO:0006996 |
266 |
0.379
|
Human Zebrafish |
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.371
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.355
|
Human |
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.339
|
Human Zebrafish |
|
|
epithelium development
|
GO:0060429 |
96 |
0.330
|
Zebrafish Fly |
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.321
|
Human |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.303
|
Human |
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.298
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.259
|
Human |
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.257
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.245
|
Zebrafish Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.226
|
Fly |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.217
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.213
|
Fly |
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.206
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.202
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.197
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.196
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.196
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.194
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.183
|
Human |
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.182
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.178
|
Zebrafish |
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.175
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.174
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.174
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.173
|
Human |
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.162
|
|
|
|
response to camp
|
GO:0051591 |
91 |
0.162
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.161
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.158
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
71 |
0.158
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.158
|
Fly |
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.153
|
Human Zebrafish |
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.150
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.150
|
Human |
|
|
programmed cell death
|
GO:0012501 |
392 |
0.146
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.141
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.138
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.138
|
Human |
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.137
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.133
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.132
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.127
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.126
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.126
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.126
|
Zebrafish Fly |
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.120
|
Fly |
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.119
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.115
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.114
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.113
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.113
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.112
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.110
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.110
|
Zebrafish |
|
|
central nervous system development
|
GO:0007417 |
311 |
0.107
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.107
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.106
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.104
|
Human |
|
|
behavior
|
GO:0007610 |
205 |
0.102
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.102
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.100
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.098
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.096
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.096
|
Human |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.095
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.094
|
|
|
|
head development
|
GO:0060322 |
247 |
0.094
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.093
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
45 |
0.091
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.091
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.091
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.090
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.089
|
Zebrafish |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.088
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.088
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.086
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.086
|
Human |
|
|
actin filament based process
|
GO:0030029 |
86 |
0.085
|
Zebrafish |
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.085
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.084
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.083
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.082
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.082
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.081
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.079
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.078
|
Human |
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.077
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.076
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.076
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.074
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.073
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.073
|
Zebrafish |
|
|
gonad development
|
GO:0008406 |
104 |
0.073
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.072
|
Human |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.072
|
Fly |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.070
|
|
|
|
growth
|
GO:0040007 |
165 |
0.068
|
Zebrafish Fly |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.068
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.068
|
Human |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.068
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.067
|
Human |
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.066
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.066
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.066
|
Fly |
|
|
cell migration
|
GO:0016477 |
197 |
0.065
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.065
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
90 |
0.064
|
Zebrafish |
|
|
regulation of body fluid levels
|
GO:0050878 |
90 |
0.063
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.062
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.062
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.062
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.062
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.062
|
Zebrafish |
|
|
catabolic process
|
GO:0009056 |
351 |
0.061
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.061
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.061
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.061
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.061
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.060
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.059
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.059
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.059
|
|
|
|
cell growth
|
GO:0016049 |
104 |
0.059
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
49 |
0.059
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.058
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.058
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.058
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.057
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.057
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.057
|
|
|
|
glycoside transport
|
GO:1901656 |
2 |
0.056
|
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.055
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
75 |
0.055
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.055
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.055
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.055
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.055
|
Fly |
|
|
reproductive system development
|
GO:0061458 |
128 |
0.054
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.054
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.054
|
Fly |
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
1 |
0.053
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.053
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.053
|
|
|
|
positive regulation of synapse maturation
|
GO:0090129 |
2 |
0.053
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.052
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.052
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.052
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.052
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.052
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.052
|
Fly |
|
|
negative regulation of neuron death
|
GO:1901215 |
69 |
0.052
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.052
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.051
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.050
|
Human |
|
|
neuron death
|
GO:0070997 |
127 |
0.050
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
66 |
0.050
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.049
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.049
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.049
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.049
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.048
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
43 |
0.048
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.048
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.048
|
Human |
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.048
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.047
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.047
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.047
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.047
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.046
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.046
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.046
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.046
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.045
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.045
|
Fly |
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.045
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.045
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.044
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.044
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.044
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.044
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.043
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
87 |
0.043
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.043
|
|
|
|
learning
|
GO:0007612 |
33 |
0.043
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.043
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.043
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.043
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.043
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
183 |
0.043
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.043
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.042
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.042
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.042
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.042
|
|
|
|
aging
|
GO:0007568 |
241 |
0.042
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
4 |
0.042
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.041
|
Zebrafish |
|
|
response to estrogen
|
GO:0043627 |
232 |
0.041
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.041
|
Fly |
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.040
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.040
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.039
|
Fly |
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.039
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
49 |
0.039
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.038
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.038
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.038
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.038
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.038
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
60 |
0.038
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.037
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.037
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.037
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
54 |
0.037
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.037
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
2 |
0.037
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
47 |
0.037
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.036
|
Human |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.036
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.036
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.036
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
1 |
0.036
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.035
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.035
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
2 |
0.035
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.035
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.035
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.034
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.034
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.034
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.034
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
118 |
0.034
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.034
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.033
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
1 |
0.033
|
|
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.033
|
|
|
|
vasculogenesis
|
GO:0001570 |
3 |
0.033
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
71 |
0.033
|
Fly |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.032
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.032
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.032
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.032
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.032
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.032
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.030
|
Fly |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.030
|
|
|
|
mesoderm formation
|
GO:0001707 |
1 |
0.030
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.030
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
47 |
0.030
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.030
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.030
|
Mouse |
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
4 |
0.030
|
|
|
|
t cell activation
|
GO:0042110 |
29 |
0.030
|
|
|
|
mesoderm development
|
GO:0007498 |
2 |
0.030
|
|
|
|
gtp metabolic process
|
GO:0046039 |
72 |
0.030
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
48 |
0.029
|
|
|
|
melanocyte differentiation
|
GO:0030318 |
2 |
0.029
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.029
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.029
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.029
|
|
|
|
olfactory learning
|
GO:0008355 |
1 |
0.029
|
|
|
|
response to vitamin
|
GO:0033273 |
131 |
0.029
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.029
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.029
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.029
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.029
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
77 |
0.028
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.028
|
Human |
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.028
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.028
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.028
|
Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.028
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.027
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.027
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.027
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
4 |
0.027
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.027
|
|
|
|
amino acid transport
|
GO:0006865 |
70 |
0.027
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.027
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
30 |
0.026
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.026
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
2 |
0.026
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.026
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
15 |
0.026
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.026
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.026
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.026
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
77 |
0.026
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.025
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.025
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.025
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.025
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.025
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.025
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
1 |
0.025
|
|
|
|
jak stat cascade
|
GO:0007259 |
26 |
0.024
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.024
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.024
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.024
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
58 |
0.024
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.023
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
29 |
0.023
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.023
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.023
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.023
|
Fly |
|
|
gamete generation
|
GO:0007276 |
124 |
0.023
|
Fly |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.023
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.023
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.023
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.023
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.023
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
9 |
0.022
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.022
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
1 |
0.022
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.022
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
70 |
0.022
|
|
|
|
gastrulation
|
GO:0007369 |
2 |
0.022
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.022
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
31 |
0.022
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
46 |
0.022
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
18 |
0.022
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
4 |
0.022
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.022
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
52 |
0.021
|
Human |
|
|
neural crest cell development
|
GO:0014032 |
2 |
0.021
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.021
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.021
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.021
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.021
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.021
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.021
|
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
3 |
0.021
|
|
|
|
male gamete generation
|
GO:0048232 |
99 |
0.021
|
|
|
|
female sex differentiation
|
GO:0046660 |
59 |
0.021
|
|
|
|
positive regulation of transforming growth factor beta3 production
|
GO:0032916 |
2 |
0.021
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
3 |
0.021
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.021
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.021
|
|
|
|
tube formation
|
GO:0035148 |
3 |
0.020
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
84 |
0.020
|
|
|
|
digestive system development
|
GO:0055123 |
41 |
0.020
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.020
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.020
|
|
|
|
eye development
|
GO:0001654 |
50 |
0.020
|
Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.020
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.020
|
|
|
|
response to retinoic acid
|
GO:0032526 |
63 |
0.020
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.020
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.019
|
Mouse |
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.019
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
8 |
0.019
|
|
|
|
response to fungicide
|
GO:0060992 |
20 |
0.019
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.019
|
|
|
|
positive regulation of smoothened signaling pathway
|
GO:0045880 |
1 |
0.019
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
56 |
0.019
|
|
|
|
maintenance of location
|
GO:0051235 |
17 |
0.019
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.019
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.019
|
|
|
|
spermatogenesis
|
GO:0007283 |
99 |
0.019
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.019
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
58 |
0.019
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.019
|
|
|
|
response to organophosphorus
|
GO:0046683 |
102 |
0.019
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.018
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.018
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.018
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.018
|
|
|
|
action potential
|
GO:0001508 |
54 |
0.018
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.018
|
|
|
|
dendrite development
|
GO:0016358 |
72 |
0.018
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.018
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.018
|
Human |
|
|
neural crest cell differentiation
|
GO:0014033 |
2 |
0.018
|
|
|
|
axis specification
|
GO:0009798 |
4 |
0.018
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.018
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.018
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
2 |
0.018
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.018
|
|
|
|
neural crest cell migration
|
GO:0001755 |
1 |
0.018
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.017
|
|
|
|
chemosensory behavior
|
GO:0007635 |
2 |
0.017
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.017
|
|
|
|
lymphocyte activation
|
GO:0046649 |
43 |
0.017
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
31 |
0.017
|
|
|
|
embryo development
|
GO:0009790 |
49 |
0.017
|
Fly |
|
|
response to peptide
|
GO:1901652 |
292 |
0.017
|
|
|
|
camera type eye development
|
GO:0043010 |
48 |
0.017
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.017
|
|
|
|
calcium ion export
|
GO:1901660 |
6 |
0.017
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
88 |
0.017
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.016
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
11 |
0.016
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.016
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
29 |
0.016
|
|
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.016
|
Fly |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.016
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.016
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
3 |
0.016
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
29 |
0.016
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.016
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.016
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
52 |
0.016
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
3 |
0.016
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.016
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
69 |
0.016
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
8 |
0.016
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
37 |
0.016
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.016
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
3 |
0.016
|
|
|
|
actin filament organization
|
GO:0007015 |
42 |
0.016
|
Zebrafish |
|
|
regulation of dendrite development
|
GO:0050773 |
59 |
0.016
|
|
|
|
positive regulation of lyase activity
|
GO:0051349 |
15 |
0.016
|
|
|
|
developmental induction
|
GO:0031128 |
2 |
0.016
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.016
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
36 |
0.016
|
|
|
|
telencephalon development
|
GO:0021537 |
62 |
0.016
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.016
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.016
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
16 |
0.016
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.016
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.015
|
|
|
|
histamine secretion by mast cell
|
GO:0002553 |
3 |
0.015
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
36 |
0.015
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.015
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.015
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.015
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
42 |
0.015
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.015
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.015
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
58 |
0.015
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.015
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
1 |
0.015
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
45 |
0.015
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
37 |
0.015
|
|
|
|
negative regulation of metanephros development
|
GO:0072217 |
2 |
0.015
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
2 |
0.015
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.015
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.015
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.015
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
2 |
0.015
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
24 |
0.015
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
35 |
0.015
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
38 |
0.015
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
28 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.015
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
43 |
0.015
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.014
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.014
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
93 |
0.014
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.014
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
59 |
0.014
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.014
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
38 |
0.014
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
22 |
0.014
|
|
|
|
cell activation
|
GO:0001775 |
97 |
0.014
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
70 |
0.014
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.014
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.014
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.014
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.014
|
Fly |
|
|
ncrna processing
|
GO:0034470 |
3 |
0.014
|
|
|
|
gtp catabolic process
|
GO:0006184 |
71 |
0.014
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.014
|
Fly |
|
|
hippocampus development
|
GO:0021766 |
30 |
0.014
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
47 |
0.014
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.014
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
71 |
0.014
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.014
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.014
|
|
|
|
regulation of dendritic spine morphogenesis
|
GO:0061001 |
6 |
0.014
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.014
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.013
|
|
|
|
intraspecies interaction between organisms
|
GO:0051703 |
15 |
0.013
|
|
|
|
neuron fate commitment
|
GO:0048663 |
4 |
0.013
|
|
|
|
regulation of calcineurin nfat signaling cascade
|
GO:0070884 |
3 |
0.013
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
33 |
0.013
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.013
|
|
|
|
regulation of organ growth
|
GO:0046620 |
13 |
0.013
|
|
|
|
regulation of cell growth
|
GO:0001558 |
85 |
0.013
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
56 |
0.013
|
|
