Rattus norvegicus

0 known processes

Ppt2

palmitoyl-protein thioesterase 2

Ppt2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.142
secretion GO:0046903 307 0.110
regulation of phosphorus metabolic process GO:0051174 349 0.096
protein phosphorylation GO:0006468 345 0.090
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.087
positive regulation of phosphorus metabolic process GO:0010562 262 0.083
regulation of cell differentiation GO:0045595 320 0.081
regulation of protein metabolic process GO:0051246 289 0.078
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.077
transmembrane transport GO:0055085 412 0.076
positive regulation of rna biosynthetic process GO:1902680 197 0.075
rna biosynthetic process GO:0032774 380 0.072
organic acid metabolic process GO:0006082 292 0.071
carboxylic acid metabolic process GO:0019752 289 0.070
cellular amino acid metabolic process GO:0006520 107 0.065
rna metabolic process GO:0016070 406 0.063
regulation of secretion GO:0051046 224 0.062
regulation of molecular function GO:0065009 398 0.061
cellular response to oxygen containing compound GO:1901701 386 0.061
cellular lipid metabolic process GO:0044255 208 0.060
nucleic acid templated transcription GO:0097659 379 0.058
regulation of signal transduction GO:0009966 318 0.056
cell cell signaling GO:0007267 335 0.055
neuronal action potential GO:0019228 35 0.054
response to extracellular stimulus GO:0009991 380 0.054
positive regulation of molecular function GO:0044093 230 0.054
regulation of cellular amino acid metabolic process GO:0006521 2 0.053
transcription dna templated GO:0006351 377 0.053
secretion by cell GO:0032940 248 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.052
regulation of rna biosynthetic process GO:2001141 381 0.052
regulation of phosphate metabolic process GO:0019220 349 0.052
positive regulation of cell proliferation GO:0008284 249 0.051
negative regulation of protein import into nucleus translocation GO:0033159 1 0.050
peptidyl amino acid modification GO:0018193 126 0.049
regulation of rna metabolic process GO:0051252 391 0.048
regulation of catalytic activity GO:0050790 304 0.047
regulation of multicellular organismal development GO:2000026 376 0.046
response to estrogen GO:0043627 232 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.045
reproductive process GO:0022414 372 0.045
cellular ketone metabolic process GO:0042180 51 0.045
regulation of secretion by cell GO:1903530 208 0.044
cellular response to nitrogen compound GO:1901699 210 0.044
regulation of cellular ketone metabolic process GO:0010565 27 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.043
cellular component assembly GO:0022607 360 0.043
transmission of nerve impulse GO:0019226 42 0.043
muscle structure development GO:0061061 87 0.043
regulation of cellular localization GO:0060341 263 0.043
multicellular organismal signaling GO:0035637 44 0.043
vesicle mediated transport GO:0016192 181 0.043
ensheathment of neurons GO:0007272 40 0.043
nitrogen compound transport GO:0071705 229 0.043
oxoacid metabolic process GO:0043436 290 0.043
action potential GO:0001508 54 0.042
axon ensheathment GO:0008366 40 0.042
negative regulation of cell proliferation GO:0008285 119 0.042
positive regulation of signaling GO:0023056 270 0.042
negative regulation of metabolic process GO:0009892 331 0.042
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
response to peptide GO:1901652 292 0.041
response to inorganic substance GO:0010035 377 0.041
positive regulation of cell communication GO:0010647 271 0.040
positive regulation of gene expression GO:0010628 244 0.040
homeostatic process GO:0042592 331 0.040
negative regulation of gene expression GO:0010629 199 0.039
central nervous system development GO:0007417 311 0.039
programmed cell death GO:0012501 392 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
multi organism reproductive process GO:0044703 262 0.037
intracellular signal transduction GO:0035556 314 0.037
positive regulation of transcription dna templated GO:0045893 197 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
regulation of programmed cell death GO:0043067 341 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.036
response to hexose GO:0009746 144 0.035
neuron differentiation GO:0030182 368 0.035
negative regulation of signaling GO:0023057 157 0.035
cellular response to organonitrogen compound GO:0071417 197 0.035
regulation of neuron differentiation GO:0045664 208 0.035
neuron projection development GO:0031175 273 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
cellular response to hormone stimulus GO:0032870 247 0.034
apoptotic process GO:0006915 381 0.034
enzyme linked receptor protein signaling pathway GO:0007167 116 0.034
negative regulation of multicellular organismal process GO:0051241 203 0.034
positive regulation of response to stimulus GO:0048584 285 0.034
organophosphate catabolic process GO:0046434 148 0.033
ras protein signal transduction GO:0007265 29 0.033
response to insulin GO:0032868 133 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
aging GO:0007568 241 0.033
positive regulation of rna metabolic process GO:0051254 203 0.032
retinoic acid receptor signaling pathway GO:0048384 7 0.032
positive regulation of cellular amine metabolic process GO:0033240 3 0.032
organelle organization GO:0006996 266 0.032
regulation of mapk cascade GO:0043408 116 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
cellular amine metabolic process GO:0044106 38 0.031
response to nutrient levels GO:0031667 370 0.031
negative regulation of cell differentiation GO:0045596 99 0.031
response to peptide hormone GO:0043434 278 0.031
neuron development GO:0048666 286 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
developmental process involved in reproduction GO:0003006 159 0.030
response to decreased oxygen levels GO:0036293 237 0.029
regulation of neurogenesis GO:0050767 247 0.029
cellular response to endogenous stimulus GO:0071495 377 0.029
regulation of cell development GO:0060284 263 0.029
aromatic compound catabolic process GO:0019439 168 0.028
axonogenesis GO:0007409 71 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
neurological system process GO:0050877 219 0.028
catabolic process GO:0009056 351 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
negative regulation of cell development GO:0010721 82 0.027
amine metabolic process GO:0009308 38 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
macromolecule localization GO:0033036 252 0.027
regulation of transcription dna templated GO:0006355 374 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.026
lipid metabolic process GO:0006629 283 0.026
negative regulation of nucleic acid templated transcription GO:1903507 117 0.026
cellular response to external stimulus GO:0071496 118 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
peptide transport GO:0015833 97 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.025
response to monosaccharide GO:0034284 159 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
myelination GO:0042552 39 0.025
carbohydrate metabolic process GO:0005975 130 0.024
organ morphogenesis GO:0009887 75 0.024
positive regulation of secretion by cell GO:1903532 128 0.024
translation GO:0006412 35 0.024
gland development GO:0048732 155 0.024
macromolecular complex assembly GO:0065003 273 0.024
negative regulation of biosynthetic process GO:0009890 168 0.024
regulation of cellular component organization GO:0051128 368 0.023
regulation of nervous system development GO:0051960 264 0.023
regulation of hydrolase activity GO:0051336 143 0.023
cellular response to peptide GO:1901653 133 0.023
regulation of lipid metabolic process GO:0019216 68 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
establishment of protein localization GO:0045184 141 0.023
regulation of apoptotic process GO:0042981 335 0.023
positive regulation of cell differentiation GO:0045597 217 0.022
organic acid catabolic process GO:0016054 49 0.022
nucleotide metabolic process GO:0009117 279 0.022
negative regulation of cell communication GO:0010648 158 0.022
ion transmembrane transport GO:0034220 365 0.022
positive regulation of signal transduction GO:0009967 175 0.022
negative regulation of transcription dna templated GO:0045892 116 0.022
positive regulation of transport GO:0051050 245 0.022
rhythmic process GO:0048511 156 0.022
brain development GO:0007420 247 0.022
negative regulation of developmental process GO:0051093 125 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
heterocycle catabolic process GO:0046700 167 0.022
multicellular organism reproduction GO:0032504 233 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
heart morphogenesis GO:0003007 3 0.021
sulfur compound metabolic process GO:0006790 70 0.021
single organism reproductive process GO:0044702 297 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
reproductive system development GO:0061458 128 0.021
regulation of phosphorylation GO:0042325 248 0.021
synaptic transmission GO:0007268 235 0.021
negative regulation of signal transduction GO:0009968 83 0.021
carbohydrate biosynthetic process GO:0016051 42 0.021
negative regulation of protein metabolic process GO:0051248 114 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.020
response to carbohydrate GO:0009743 183 0.020
cellular catabolic process GO:0044248 295 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
response to hypoxia GO:0001666 231 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
signal release GO:0023061 145 0.019
endocytosis GO:0006897 84 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
cellular component biogenesis GO:0044085 368 0.019
regulation of translation GO:0006417 27 0.019
monosaccharide metabolic process GO:0005996 61 0.019
membrane organization GO:0061024 94 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
regulation of system process GO:0044057 208 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
organic substance catabolic process GO:1901575 316 0.019
intracellular transport GO:0046907 185 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
posttranscriptional regulation of gene expression GO:0010608 37 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.018
cellular carbohydrate metabolic process GO:0044262 72 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of membrane potential GO:0042391 110 0.018
protein complex subunit organization GO:0071822 302 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
response to ethanol GO:0045471 162 0.018
positive regulation of developmental process GO:0051094 283 0.018
nucleoside metabolic process GO:0009116 179 0.018
muscle system process GO:0003012 115 0.018
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.018
hormone secretion GO:0046879 115 0.018
peptide hormone secretion GO:0030072 84 0.018
regulation of growth GO:0040008 105 0.018
reproductive structure development GO:0048608 128 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cell projection organization GO:0030030 302 0.018
cellular response to insulin stimulus GO:0032869 81 0.018
response to ketone GO:1901654 182 0.018
response to oxygen levels GO:0070482 265 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
female pregnancy GO:0007565 122 0.017
single organism catabolic process GO:0044712 283 0.017
response to nutrient GO:0007584 248 0.017
negative regulation of cell death GO:0060548 229 0.017
amide transport GO:0042886 105 0.017
regulation of vesicle mediated transport GO:0060627 81 0.017
cellular response to stress GO:0033554 269 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to glucocorticoid GO:0051384 223 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
cell projection morphogenesis GO:0048858 123 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
positive regulation of protein modification process GO:0031401 142 0.017
single organism biosynthetic process GO:0044711 342 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
behavior GO:0007610 205 0.017
reproduction GO:0000003 245 0.016
hepaticobiliary system development GO:0061008 90 0.016
small molecule biosynthetic process GO:0044283 124 0.016
protein oligomerization GO:0051259 191 0.016
response to reactive oxygen species GO:0000302 120 0.016
axis specification GO:0009798 4 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
organ regeneration GO:0031100 101 0.016
sexual reproduction GO:0019953 148 0.016
negative regulation of molecular function GO:0044092 133 0.016
single organism intracellular transport GO:1902582 166 0.016
chemical homeostasis GO:0048878 292 0.016
purine containing compound catabolic process GO:0072523 138 0.016
blood circulation GO:0008015 183 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
response to acid chemical GO:0001101 222 0.016
gliogenesis GO:0042063 93 0.016
regulation of protein transport GO:0051223 68 0.015
multicellular organism growth GO:0035264 1 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
tissue development GO:0009888 252 0.015
anion transport GO:0006820 178 0.015
purine containing compound metabolic process GO:0072521 253 0.015
positive regulation of cell development GO:0010720 176 0.015
cell cycle GO:0007049 101 0.015
protein processing GO:0016485 68 0.015
positive regulation of cell death GO:0010942 184 0.015
regulation of activation of jak2 kinase activity GO:0010534 1 0.015
response to wounding GO:0009611 254 0.015
circulatory system process GO:0003013 183 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
embryonic pattern specification GO:0009880 1 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
regulation of catabolic process GO:0009894 113 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
response to metal ion GO:0010038 253 0.015
single organism organelle organization GO:1902589 180 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
response to growth factor GO:0070848 189 0.015
neuron death GO:0070997 127 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
regulation of hormone secretion GO:0046883 106 0.015
organophosphate metabolic process GO:0019637 370 0.015
regulation of establishment of protein localization GO:0070201 69 0.014
chemosensory behavior GO:0007635 2 0.014
striated muscle tissue development GO:0014706 58 0.014
regulation of response to stress GO:0080134 126 0.014
regulation of protein targeting GO:1903533 28 0.014
negative regulation of nervous system development GO:0051961 79 0.014
cellular protein localization GO:0034613 122 0.014
regulation of transferase activity GO:0051338 123 0.014
male gamete generation GO:0048232 99 0.014
negative regulation of transport GO:0051051 136 0.014
regulation of cell cycle GO:0051726 73 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
positive regulation of nervous system development GO:0051962 178 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
proteolysis GO:0006508 175 0.014
carboxylic acid catabolic process GO:0046395 49 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.013
response to glucose GO:0009749 136 0.013
response to organophosphorus GO:0046683 102 0.013
positive regulation of secretion GO:0051047 140 0.013
protein localization GO:0008104 191 0.013
response to camp GO:0051591 91 0.013
lipid biosynthetic process GO:0008610 128 0.013
regulation of immune system process GO:0002682 123 0.013
nucleoside catabolic process GO:0009164 126 0.013
cell activation GO:0001775 97 0.013
hormone transport GO:0009914 121 0.013
cellular component movement GO:0006928 248 0.013
response to oxidative stress GO:0006979 186 0.013
regulation of hormone levels GO:0010817 187 0.013
circulatory system development GO:0072359 134 0.013
protein secretion GO:0009306 34 0.013
microvillus assembly GO:0030033 2 0.013
nucleotide catabolic process GO:0009166 139 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
circadian rhythm GO:0007623 88 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
response to temperature stimulus GO:0009266 94 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
cellular component morphogenesis GO:0032989 155 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
gtp metabolic process GO:0046039 72 0.013
cytokine production GO:0001816 61 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
cardiovascular system development GO:0072358 134 0.013
cellular chemical homeostasis GO:0055082 247 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
chemotaxis GO:0006935 66 0.012
taxis GO:0042330 67 0.012
coenzyme metabolic process GO:0006732 86 0.012
protein complex assembly GO:0006461 263 0.012
cellular homeostasis GO:0019725 252 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
establishment of tissue polarity GO:0007164 2 0.012
kidney development GO:0001822 67 0.012
gamete generation GO:0007276 124 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cardiac muscle tissue morphogenesis GO:0055008 1 0.012
negative regulation of intracellular signal transduction GO:1902532 38 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
single organism membrane organization GO:0044802 74 0.012
jak stat cascade GO:0007259 26 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
neuron projection morphogenesis GO:0048812 122 0.012
hexose metabolic process GO:0019318 58 0.012
protein complex biogenesis GO:0070271 263 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
maintenance of location GO:0051235 17 0.012
regulation of peptide transport GO:0090087 87 0.012
response to vitamin GO:0033273 131 0.012
regulation of t cell activation GO:0050863 23 0.011
muscle tissue development GO:0060537 58 0.011
growth GO:0040007 165 0.011
maternal process involved in female pregnancy GO:0060135 38 0.011
lipid storage GO:0019915 1 0.011
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.011
cell cycle checkpoint GO:0000075 2 0.011
regeneration GO:0031099 163 0.011
regulation of carbohydrate metabolic process GO:0006109 41 0.011
glucan metabolic process GO:0044042 23 0.011
positive regulation of immune system process GO:0002684 90 0.011
localization of cell GO:0051674 202 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
axon development GO:0061564 96 0.011
cell part morphogenesis GO:0032990 123 0.011
urogenital system development GO:0001655 78 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
protein transport GO:0015031 132 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
peptide secretion GO:0002790 86 0.011
regulation of neuron death GO:1901214 115 0.011
muscle organ development GO:0007517 50 0.011
organic hydroxy compound transport GO:0015850 77 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of catabolic process GO:0009896 78 0.011
glycerolipid metabolic process GO:0046486 67 0.011
mapk cascade GO:0000165 140 0.011
tissue remodeling GO:0048771 40 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
cation transport GO:0006812 382 0.011
cytoplasmic transport GO:0016482 115 0.011
olfactory behavior GO:0042048 2 0.011
regulation of cell projection organization GO:0031344 175 0.011
muscle cell differentiation GO:0042692 52 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
ribonucleoside catabolic process GO:0042454 126 0.010
gonad development GO:0008406 104 0.010
sex differentiation GO:0007548 113 0.010
organ formation GO:0048645 3 0.010
intracellular protein transport GO:0006886 79 0.010
fatty acid metabolic process GO:0006631 99 0.010
heart development GO:0007507 72 0.010
single organism behavior GO:0044708 130 0.010
response to purine containing compound GO:0014074 126 0.010
locomotion GO:0040011 237 0.010
glucose metabolic process GO:0006006 52 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
regulation of cytokine production GO:0001817 56 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of protein kinase activity GO:0045859 105 0.010
acetyl coa metabolic process GO:0006084 17 0.010
positive regulation of mitochondrion organization GO:0010822 4 0.010
protein heterooligomerization GO:0051291 89 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
lipid modification GO:0030258 52 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
regulation of synaptic plasticity GO:0048167 70 0.010

Ppt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014
colon carcinoma DOID:1520 0 0.010
colorectal cancer DOID:9256 0 0.010
colon cancer DOID:219 0 0.010
large intestine cancer DOID:5672 0 0.010
intestinal cancer DOID:10155 0 0.010
gastrointestinal system cancer DOID:3119 0 0.010