Rattus norvegicus

8 known processes

Prdx1

peroxiredoxin 1

(Aliases: Hbp23,MGC108617)

Prdx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leydig cell differentiation GO:0033327 8 0.627
oxidation reduction process GO:0055114 304 0.609
single organism catabolic process GO:0044712 283 0.380
Human
synaptic transmission GO:0007268 235 0.346
organic acid metabolic process GO:0006082 292 0.334
cellular ketone metabolic process GO:0042180 51 0.334
cellular catabolic process GO:0044248 295 0.325
Human
synaptic transmission gabaergic GO:0051932 22 0.321
response to oxidative stress GO:0006979 186 0.294
oxoacid metabolic process GO:0043436 290 0.287
development of primary sexual characteristics GO:0045137 107 0.286
brain development GO:0007420 247 0.275
response to extracellular stimulus GO:0009991 380 0.272
developmental process involved in reproduction GO:0003006 159 0.262
head development GO:0060322 247 0.253
regulation of cellular localization GO:0060341 263 0.228
carboxylic acid metabolic process GO:0019752 289 0.213
response to glucocorticoid GO:0051384 223 0.213
central nervous system development GO:0007417 311 0.204
response to corticosteroid GO:0031960 235 0.203
regulation of ion transport GO:0043269 245 0.197
response to nutrient levels GO:0031667 370 0.197
cellular response to stress GO:0033554 269 0.193
Human
negative regulation of cellular metabolic process GO:0031324 281 0.188
cellular divalent inorganic cation homeostasis GO:0072503 162 0.183
reproductive system development GO:0061458 128 0.181
response to hydrogen peroxide GO:0042542 89 0.177
Human
response to reactive oxygen species GO:0000302 120 0.175
Human
reproductive structure development GO:0048608 128 0.174
regulation of synaptic transmission GO:0050804 141 0.173
intracellular transport GO:0046907 185 0.172
aging GO:0007568 241 0.169
negative regulation of response to stimulus GO:0048585 155 0.161
cellular response to reactive oxygen species GO:0034614 55 0.160
Human
cell cell signaling GO:0007267 335 0.158
pigment biosynthetic process GO:0046148 4 0.145
regulation of cellular ketone metabolic process GO:0010565 27 0.143
cation transport GO:0006812 382 0.136
regulation of cellular catabolic process GO:0031329 101 0.134
calcium ion homeostasis GO:0055074 162 0.133
reproductive process GO:0022414 372 0.133
cellular homeostasis GO:0019725 252 0.131
organic substance catabolic process GO:1901575 316 0.130
response to cadmium ion GO:0046686 35 0.128
single organism intracellular transport GO:1902582 166 0.122
response to inorganic substance GO:0010035 377 0.120
Human
cellular response to organonitrogen compound GO:0071417 197 0.119
gonad development GO:0008406 104 0.117
fatty acid oxidation GO:0019395 29 0.115
regulation of programmed cell death GO:0043067 341 0.114
Rat
negative regulation of metabolic process GO:0009892 331 0.113
cytosolic calcium ion homeostasis GO:0051480 140 0.113
cation homeostasis GO:0055080 195 0.112
positive regulation of transport GO:0051050 245 0.112
lipid metabolic process GO:0006629 283 0.112
cellular chemical homeostasis GO:0055082 247 0.107
positive regulation of biosynthetic process GO:0009891 319 0.106
divalent metal ion transport GO:0070838 132 0.102
programmed cell death GO:0012501 392 0.102
Rat
single organism reproductive process GO:0044702 297 0.102
organic acid catabolic process GO:0016054 49 0.101
secretion GO:0046903 307 0.099
ion homeostasis GO:0050801 212 0.096
regulation of molecular function GO:0065009 398 0.094
metal ion transport GO:0030001 289 0.090
regulation of cellular protein metabolic process GO:0032268 267 0.089
cellular component assembly GO:0022607 360 0.089
reproduction GO:0000003 245 0.088
negative regulation of programmed cell death GO:0043069 183 0.087
Rat
cellular response to external stimulus GO:0071496 118 0.086
metal ion homeostasis GO:0055065 186 0.083
cellular lipid metabolic process GO:0044255 208 0.082
regulation of body fluid levels GO:0050878 90 0.078
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.078
response to acid chemical GO:0001101 222 0.076
cellular calcium ion homeostasis GO:0006874 160 0.075
organic acid biosynthetic process GO:0016053 83 0.075
cellular response to endogenous stimulus GO:0071495 377 0.073
cellular response to oxidative stress GO:0034599 76 0.073
Human
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.073
response to metal ion GO:0010038 253 0.072
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.072
single organism biosynthetic process GO:0044711 342 0.072
regulation of intracellular signal transduction GO:1902531 218 0.071
cellular cation homeostasis GO:0030003 180 0.069
divalent inorganic cation homeostasis GO:0072507 165 0.068
lipid biosynthetic process GO:0008610 128 0.067
catabolic process GO:0009056 351 0.067
Human
apoptotic process GO:0006915 381 0.065
Rat
protein complex subunit organization GO:0071822 302 0.065
sex differentiation GO:0007548 113 0.063
response to ketone GO:1901654 182 0.063
negative regulation of macromolecule metabolic process GO:0010605 260 0.063
multicellular organism reproduction GO:0032504 233 0.063
regulation of lipid biosynthetic process GO:0046890 38 0.062
cellular response to hormone stimulus GO:0032870 247 0.060
regulation of metal ion transport GO:0010959 118 0.059
inflammatory response GO:0006954 150 0.059
regulation of catabolic process GO:0009894 113 0.059
response to cytokine GO:0034097 215 0.058
protein complex assembly GO:0006461 263 0.058
lipid catabolic process GO:0016042 46 0.057
macromolecular complex assembly GO:0065003 273 0.057
response to nutrient GO:0007584 248 0.056
gliogenesis GO:0042063 93 0.056
negative regulation of cell death GO:0060548 229 0.055
Rat
chemical homeostasis GO:0048878 292 0.054
divalent inorganic cation transport GO:0072511 134 0.053
behavior GO:0007610 205 0.052
small molecule catabolic process GO:0044282 59 0.052
positive regulation of ion transport GO:0043270 94 0.050
organ regeneration GO:0031100 101 0.050
locomotion GO:0040011 237 0.050
negative regulation of cellular biosynthetic process GO:0031327 161 0.050
calcium ion transport GO:0006816 131 0.049
protein phosphorylation GO:0006468 345 0.049
positive regulation of calcium ion transport GO:0051928 36 0.048
response to other organism GO:0051707 220 0.048
cellular response to extracellular stimulus GO:0031668 73 0.048
l glutamate import GO:0051938 2 0.048
cellular ion homeostasis GO:0006873 184 0.047
negative regulation of transport GO:0051051 136 0.047
fatty acid catabolic process GO:0009062 26 0.046
response to insulin GO:0032868 133 0.046
cell redox homeostasis GO:0045454 1 0.046
single organism carbohydrate metabolic process GO:0044723 118 0.046
calcium ion transport into cytosol GO:0060402 38 0.045
negative regulation of fatty acid oxidation GO:0046322 2 0.045
response to carbohydrate GO:0009743 183 0.045
small molecule biosynthetic process GO:0044283 124 0.044
regulation of phosphorus metabolic process GO:0051174 349 0.043
regulation of intracellular transport GO:0032386 65 0.043
response to peptide GO:1901652 292 0.043
response to amino acid GO:0043200 75 0.043
nucleic acid templated transcription GO:0097659 379 0.043
response to monosaccharide GO:0034284 159 0.041
response to biotic stimulus GO:0009607 226 0.041
defense response GO:0006952 194 0.041
cellular metal ion homeostasis GO:0006875 172 0.041
vesicle organization GO:0016050 29 0.041
macromolecule catabolic process GO:0009057 58 0.040
multicellular organismal reproductive process GO:0048609 233 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.039
regulation of calcium ion transport GO:0051924 77 0.039
spermatogenesis GO:0007283 99 0.039
negative regulation of fatty acid beta oxidation GO:0031999 2 0.038
regulation of protein metabolic process GO:0051246 289 0.037
response to toxic substance GO:0009636 133 0.036
vesicle mediated transport GO:0016192 181 0.036
multi organism reproductive process GO:0044703 262 0.036
protein oligomerization GO:0051259 191 0.036
carbohydrate metabolic process GO:0005975 130 0.036
response to growth factor GO:0070848 189 0.036
response to molecule of bacterial origin GO:0002237 194 0.036
positive regulation of protein phosphorylation GO:0001934 135 0.036
regulation of rna biosynthetic process GO:2001141 381 0.036
negative regulation of signaling GO:0023057 157 0.036
membrane organization GO:0061024 94 0.035
regulation of response to stress GO:0080134 126 0.035
regulation of fatty acid metabolic process GO:0019217 18 0.035
male sex differentiation GO:0046661 64 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
Human
regulation of synaptic transmission gabaergic GO:0032228 17 0.035
positive regulation of molecular function GO:0044093 230 0.034
protein complex biogenesis GO:0070271 263 0.034
fatty acid metabolic process GO:0006631 99 0.033
response to lead ion GO:0010288 33 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.033
response to herbicide GO:0009635 16 0.033
positive regulation of lipid biosynthetic process GO:0046889 25 0.033
porphyrin containing compound metabolic process GO:0006778 8 0.033
neurotransmitter uptake GO:0001504 3 0.033
cellular response to glucocorticoid stimulus GO:0071385 68 0.032
intracellular protein transport GO:0006886 79 0.031
male gonad development GO:0008584 59 0.031
regulation of signal transduction GO:0009966 318 0.031
cellular protein catabolic process GO:0044257 19 0.031
cellular response to nitrogen compound GO:1901699 210 0.031
response to peptide hormone GO:0043434 278 0.031
nucleoside monophosphate metabolic process GO:0009123 93 0.030
tetrapyrrole metabolic process GO:0033013 11 0.030
sexual reproduction GO:0019953 148 0.030
regulation of cell proliferation GO:0042127 359 0.030
ribonucleotide metabolic process GO:0009259 231 0.029
proteasomal protein catabolic process GO:0010498 8 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
sequestering of metal ion GO:0051238 9 0.029
cellular amine metabolic process GO:0044106 38 0.029
cytoplasmic transport GO:0016482 115 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
proteolysis GO:0006508 175 0.028
organelle organization GO:0006996 266 0.028
regulation of response to external stimulus GO:0032101 106 0.027
response to thyroxine GO:0097068 3 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
regulation of calcium ion transport into cytosol GO:0010522 25 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
response to hyperoxia GO:0055093 45 0.027
male gamete generation GO:0048232 99 0.026
carboxylic acid biosynthetic process GO:0046394 83 0.026
carboxylic acid catabolic process GO:0046395 49 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
Rat
monocarboxylic acid catabolic process GO:0072329 28 0.025
macromolecule localization GO:0033036 252 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
positive regulation of lipid metabolic process GO:0045834 33 0.025
response to glucose GO:0009749 136 0.025
negative regulation of biosynthetic process GO:0009890 168 0.024
cellular protein localization GO:0034613 122 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
pyridine containing compound metabolic process GO:0072524 32 0.024
cell projection organization GO:0030030 302 0.024
positive regulation of signal transduction GO:0009967 175 0.023
response to estradiol GO:0032355 164 0.023
response to estrogen GO:0043627 232 0.023
cellular response to nutrient levels GO:0031669 60 0.023
steroid biosynthetic process GO:0006694 48 0.023
cellular modified amino acid metabolic process GO:0006575 61 0.023
establishment of vesicle localization GO:0051650 31 0.023
response to vitamin GO:0033273 131 0.023
regulation of lipid metabolic process GO:0019216 68 0.023
positive regulation of cytoplasmic transport GO:1903651 32 0.023
positive regulation of mitochondrial membrane permeability GO:0035794 1 0.023
cellular response to insulin stimulus GO:0032869 81 0.023
maintenance of location GO:0051235 17 0.022
regulation of catalytic activity GO:0050790 304 0.022
sequestering of calcium ion GO:0051208 8 0.022
negative regulation of lipid catabolic process GO:0050995 6 0.022
positive regulation of homeostatic process GO:0032846 49 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
insecticide metabolic process GO:0017143 4 0.021
cellular component biogenesis GO:0044085 368 0.021
neurotransmitter transport GO:0006836 42 0.021
reactive oxygen species metabolic process GO:0072593 37 0.021
Human
adenine nucleotide transport GO:0051503 2 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
negative regulation of gene expression GO:0010629 199 0.021
nitrogen compound transport GO:0071705 229 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
regulation of protein maturation GO:1903317 50 0.021
secretion by cell GO:0032940 248 0.020
negative regulation of cell communication GO:0010648 158 0.020
regulation of rna metabolic process GO:0051252 391 0.020
tissue development GO:0009888 252 0.020
single organism membrane organization GO:0044802 74 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
response to dexamethasone GO:0071548 49 0.020
synaptic growth at neuromuscular junction GO:0051124 1 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
protein localization GO:0008104 191 0.020
digestion GO:0007586 26 0.019
immune response GO:0006955 104 0.019
glial cell differentiation GO:0010001 65 0.019
immune system process GO:0002376 204 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 9 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
regulation of transcription dna templated GO:0006355 374 0.019
mitochondrial calcium ion homeostasis GO:0051560 3 0.019
molting cycle GO:0042303 3 0.018
synaptic vesicle localization GO:0097479 24 0.018
response to ethanol GO:0045471 162 0.018
cellular macromolecule localization GO:0070727 122 0.018
regulation of fatty acid beta oxidation GO:0031998 8 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
response to wounding GO:0009611 254 0.018
negative regulation of molecular function GO:0044092 133 0.018
regulation of protein modification process GO:0031399 194 0.018
regulation of ion homeostasis GO:2000021 63 0.018
regulation of phosphate metabolic process GO:0019220 349 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.017
epithelium development GO:0060429 96 0.017
cellular lipid catabolic process GO:0044242 37 0.017
negative regulation of signal transduction GO:0009968 83 0.017
response to hexose GO:0009746 144 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
positive regulation of intracellular transport GO:0032388 39 0.017
regulation of kinase activity GO:0043549 117 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
response to bacterium GO:0009617 200 0.017
regulation of hydrolase activity GO:0051336 143 0.016
cellular response to peptide GO:1901653 133 0.016
response to external biotic stimulus GO:0043207 221 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of protein modification process GO:0031401 142 0.016
protein homooligomerization GO:0051260 91 0.016
purine nucleotide transport GO:0015865 3 0.016
response to oxygen levels GO:0070482 265 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
cellular amide metabolic process GO:0043603 44 0.016
neuron projection development GO:0031175 273 0.016
regulation of phosphorylation GO:0042325 248 0.016
single organism organelle organization GO:1902589 180 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
neuron differentiation GO:0030182 368 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
body fluid secretion GO:0007589 41 0.015
negative regulation of homeostatic process GO:0032845 47 0.015
intracellular signal transduction GO:0035556 314 0.015
development of primary male sexual characteristics GO:0046546 59 0.015
protein transport GO:0015031 132 0.015
heme biosynthetic process GO:0006783 4 0.015
embryo development GO:0009790 49 0.015
transcription dna templated GO:0006351 377 0.015
protein localization to membrane GO:0072657 36 0.015
regulation of defense response GO:0031347 68 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.014
forebrain development GO:0030900 98 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
negative regulation of peptidase activity GO:0010466 38 0.014
organophosphate metabolic process GO:0019637 370 0.014
cellular component movement GO:0006928 248 0.014
molting cycle process GO:0022404 2 0.014
regulation of neuron death GO:1901214 115 0.014
Rat
digestive system process GO:0022600 24 0.014
regulation of hormone levels GO:0010817 187 0.013
establishment of protein localization GO:0045184 141 0.013
hair cycle process GO:0022405 2 0.013
multi multicellular organism process GO:0044706 138 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
regulation of mitochondrial membrane permeability GO:0046902 5 0.013
gamete generation GO:0007276 124 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
cell growth GO:0016049 104 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
cellular response to oxygen levels GO:0071453 60 0.013
negative regulation of protein processing GO:0010955 47 0.013
regulation of protein phosphorylation GO:0001932 183 0.012
cellular response to hydrogen peroxide GO:0070301 42 0.012
Human
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of atp biosynthetic process GO:2001169 2 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to organophosphorus GO:0046683 102 0.012
positive regulation of calcium ion transport into cytosol GO:0010524 16 0.012
regulation of protein transport GO:0051223 68 0.012
telencephalon development GO:0021537 62 0.012
limbic system development GO:0021761 38 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cytosolic calcium ion transport GO:0060401 39 0.012
cellular response to nutrient GO:0031670 30 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
regulation of cell adhesion GO:0030155 52 0.012
regulation of protein processing GO:0070613 50 0.012
dicarboxylic acid transport GO:0006835 34 0.012
hair follicle development GO:0001942 2 0.012
anion transport GO:0006820 178 0.012
cytoskeleton organization GO:0007010 111 0.011
purine containing compound metabolic process GO:0072521 253 0.011
vesicle localization GO:0051648 33 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
regulation of secretion GO:0051046 224 0.011
response to increased oxygen levels GO:0036296 45 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
regulation of cellular response to stress GO:0080135 49 0.011
synaptic vesicle transport GO:0048489 23 0.011
hippocampus development GO:0021766 30 0.011
protein localization to nucleus GO:0034504 39 0.011
rna metabolic process GO:0016070 406 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
nadp metabolic process GO:0006739 13 0.011
neuron apoptotic process GO:0051402 88 0.011
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
regulation of response to wounding GO:1903034 69 0.011
purine containing compound catabolic process GO:0072523 138 0.011
adult locomotory behavior GO:0008344 4 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
positive regulation of cell communication GO:0010647 271 0.010
epithelial cell differentiation GO:0030855 71 0.010
regulation of peptidase activity GO:0052547 55 0.010
amine metabolic process GO:0009308 38 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
cellular response to corticosteroid stimulus GO:0071384 69 0.010
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.010
regulation of immune system process GO:0002682 123 0.010
negative regulation of hydrolase activity GO:0051346 52 0.010

Prdx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 0 0.011
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011
electroclinical syndrome DOID:0050701 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011