Rattus norvegicus

0 known processes

Prelp

proline/arginine-rich end leucine-rich repeat protein

Prelp biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
wound healing GO:0042060 122 0.436
response to cytokine GO:0034097 215 0.259
response to corticosteroid GO:0031960 235 0.171
cellular response to endogenous stimulus GO:0071495 377 0.151
regulation of cellular protein metabolic process GO:0032268 267 0.145
response to wounding GO:0009611 254 0.137
reproductive process GO:0022414 372 0.129
single organism reproductive process GO:0044702 297 0.125
regulation of apoptotic process GO:0042981 335 0.122
regeneration GO:0031099 163 0.121
renal system development GO:0072001 67 0.120
regulation of phosphate metabolic process GO:0019220 349 0.098
glomerulus vasculature development GO:0072012 6 0.097
organophosphate metabolic process GO:0019637 370 0.086
rna biosynthetic process GO:0032774 380 0.085
rhythmic process GO:0048511 156 0.084
negative regulation of cellular metabolic process GO:0031324 281 0.084
reproductive system development GO:0061458 128 0.083
regulation of multicellular organismal development GO:2000026 376 0.081
secretion GO:0046903 307 0.081
kidney development GO:0001822 67 0.079
regulation of neurogenesis GO:0050767 247 0.078
defense response GO:0006952 194 0.078
cellular response to cytokine stimulus GO:0071345 127 0.076
response to metal ion GO:0010038 253 0.073
cellular response to interleukin 1 GO:0071347 37 0.072
organ regeneration GO:0031100 101 0.072
regulation of catalytic activity GO:0050790 304 0.069
response to other organism GO:0051707 220 0.067
development of primary sexual characteristics GO:0045137 107 0.065
respiratory system development GO:0060541 45 0.064
multicellular organism reproduction GO:0032504 233 0.064
positive regulation of neurogenesis GO:0050769 165 0.064
multi organism reproductive process GO:0044703 262 0.063
cellular response to hormone stimulus GO:0032870 247 0.062
apoptotic process GO:0006915 381 0.061
regulation of protein metabolic process GO:0051246 289 0.061
positive regulation of phosphate metabolic process GO:0045937 262 0.059
response to oxygen levels GO:0070482 265 0.059
protein complex assembly GO:0006461 263 0.058
regulation of nervous system development GO:0051960 264 0.058
cardiovascular system development GO:0072358 134 0.058
protein oligomerization GO:0051259 191 0.057
central nervous system development GO:0007417 311 0.056
response to estrogen GO:0043627 232 0.055
regulation of body fluid levels GO:0050878 90 0.055
ovulation cycle GO:0042698 67 0.055
regulation of cell development GO:0060284 263 0.054
regulation of molecular function GO:0065009 398 0.053
macromolecular complex assembly GO:0065003 273 0.053
multicellular organismal reproductive process GO:0048609 233 0.053
nucleoside phosphate metabolic process GO:0006753 283 0.052
macromolecular complex subunit organization GO:0043933 339 0.051
regulation of neuron projection development GO:0010975 161 0.051
positive regulation of phosphorus metabolic process GO:0010562 262 0.050
head development GO:0060322 247 0.050
positive regulation of multicellular organismal process GO:0051240 387 0.049
protein complex subunit organization GO:0071822 302 0.049
response to hexose GO:0009746 144 0.049
cellular component assembly GO:0022607 360 0.048
negative regulation of cell death GO:0060548 229 0.048
response to interleukin 2 GO:0070669 1 0.047
immune system process GO:0002376 204 0.047
tissue development GO:0009888 252 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
response to growth factor GO:0070848 189 0.045
reproduction GO:0000003 245 0.044
neuron differentiation GO:0030182 368 0.044
single organism biosynthetic process GO:0044711 342 0.043
negative regulation of gene expression GO:0010629 199 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
positive regulation of developmental process GO:0051094 283 0.042
regulation of secretion by cell GO:1903530 208 0.042
positive regulation of response to stimulus GO:0048584 285 0.042
cellular response to organic cyclic compound GO:0071407 202 0.042
embryo implantation GO:0007566 15 0.042
response to glucose GO:0009749 136 0.041
ribose phosphate metabolic process GO:0019693 235 0.040
growth GO:0040007 165 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
regulation of cell differentiation GO:0045595 320 0.039
regulation of protein phosphorylation GO:0001932 183 0.039
negative regulation of metabolic process GO:0009892 331 0.039
neurological system process GO:0050877 219 0.038
regulation of neuron differentiation GO:0045664 208 0.038
response to decreased oxygen levels GO:0036293 237 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.037
cellular chemical homeostasis GO:0055082 247 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.036
response to bacterium GO:0009617 200 0.036
secretion by cell GO:0032940 248 0.036
urogenital system development GO:0001655 78 0.035
tissue regeneration GO:0042246 36 0.035
response to nutrient levels GO:0031667 370 0.034
response to peptide hormone GO:0043434 278 0.034
response to vitamin GO:0033273 131 0.034
multi multicellular organism process GO:0044706 138 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.034
intracellular signal transduction GO:0035556 314 0.034
protein complex biogenesis GO:0070271 263 0.033
regulation of cellular component organization GO:0051128 368 0.033
negative regulation of cell proliferation GO:0008285 119 0.033
response to glucocorticoid GO:0051384 223 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
circulatory system development GO:0072359 134 0.032
transcription dna templated GO:0006351 377 0.032
response to interleukin 1 GO:0070555 55 0.032
tube development GO:0035295 89 0.032
cyclic nucleotide metabolic process GO:0009187 80 0.032
gonad development GO:0008406 104 0.032
developmental process involved in reproduction GO:0003006 159 0.031
positive regulation of nervous system development GO:0051962 178 0.031
regulation of hydrolase activity GO:0051336 143 0.031
protein homooligomerization GO:0051260 91 0.031
positive regulation of gene expression GO:0010628 244 0.030
response to estradiol GO:0032355 164 0.030
cellular component biogenesis GO:0044085 368 0.030
muscle structure development GO:0061061 87 0.030
reproductive structure development GO:0048608 128 0.029
response to monosaccharide GO:0034284 159 0.029
cell cell signaling GO:0007267 335 0.029
programmed cell death GO:0012501 392 0.029
regulation of response to stress GO:0080134 126 0.028
lipid metabolic process GO:0006629 283 0.028
aging GO:0007568 241 0.028
Mouse
regulation of cell proliferation GO:0042127 359 0.028
regulation of response to wounding GO:1903034 69 0.028
hemostasis GO:0007599 26 0.028
cell projection organization GO:0030030 302 0.028
nucleotide metabolic process GO:0009117 279 0.027
chemical homeostasis GO:0048878 292 0.027
regulation of programmed cell death GO:0043067 341 0.027
nucleic acid templated transcription GO:0097659 379 0.027
response to ketone GO:1901654 182 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
kidney vasculature development GO:0061440 6 0.027
response to carbohydrate GO:0009743 183 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
response to toxic substance GO:0009636 133 0.026
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
female pregnancy GO:0007565 122 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
negative regulation of cell differentiation GO:0045596 99 0.025
ras protein signal transduction GO:0007265 29 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
cyclic purine nucleotide metabolic process GO:0052652 62 0.025
regulation of cellular component movement GO:0051270 150 0.025
response to hypoxia GO:0001666 231 0.025
blood vessel development GO:0001568 69 0.025
telencephalon development GO:0021537 62 0.025
positive regulation of signaling GO:0023056 270 0.024
protein phosphorylation GO:0006468 345 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
response to inorganic substance GO:0010035 377 0.024
positive regulation of protein modification process GO:0031401 142 0.024
positive regulation of cell development GO:0010720 176 0.024
vasculature development GO:0001944 70 0.023
regulation of signal transduction GO:0009966 318 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
positive regulation of molecular function GO:0044093 230 0.023
blood vessel morphogenesis GO:0048514 58 0.023
response to external biotic stimulus GO:0043207 221 0.023
purine containing compound metabolic process GO:0072521 253 0.023
cellular homeostasis GO:0019725 252 0.023
mapk cascade GO:0000165 140 0.023
response to retinoic acid GO:0032526 63 0.023
proteolysis GO:0006508 175 0.022
positive regulation of cellular component movement GO:0051272 102 0.022
organ morphogenesis GO:0009887 75 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
nucleotide catabolic process GO:0009166 139 0.022
organic acid metabolic process GO:0006082 292 0.022
cytosolic calcium ion homeostasis GO:0051480 140 0.022
response to nutrient GO:0007584 248 0.021
neuron projection development GO:0031175 273 0.021
negative regulation of molecular function GO:0044092 133 0.021
response to extracellular stimulus GO:0009991 380 0.021
regulation of phosphorylation GO:0042325 248 0.021
regulation of defense response GO:0031347 68 0.021
response to peptide GO:1901652 292 0.021
ion homeostasis GO:0050801 212 0.020
regulation of peptidase activity GO:0052547 55 0.020
positive regulation of cell communication GO:0010647 271 0.020
striated muscle tissue development GO:0014706 58 0.020
developmental growth GO:0048589 100 0.020
blood coagulation GO:0007596 26 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
cellular amine metabolic process GO:0044106 38 0.020
regulation of transcription dna templated GO:0006355 374 0.020
cell activation GO:0001775 97 0.020
regulation of nucleotide metabolic process GO:0006140 117 0.019
response to radiation GO:0009314 137 0.019
immune response GO:0006955 104 0.019
response to oxidative stress GO:0006979 186 0.019
negative regulation of protein maturation GO:1903318 47 0.019
regulation of immune system process GO:0002682 123 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
cellular response to lipid GO:0071396 201 0.019
inflammatory response GO:0006954 150 0.019
response to acid chemical GO:0001101 222 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
positive regulation of cell death GO:0010942 184 0.018
regulation of hormone levels GO:0010817 187 0.018
ribose phosphate biosynthetic process GO:0046390 87 0.018
nucleoside phosphate catabolic process GO:1901292 140 0.018
regulation of cell growth GO:0001558 85 0.018
regulation of cellular localization GO:0060341 263 0.018
protein localization GO:0008104 191 0.018
cellular response to nitrogen compound GO:1901699 210 0.017
cation transport GO:0006812 382 0.017
cation homeostasis GO:0055080 195 0.017
nitrogen compound transport GO:0071705 229 0.017
protein processing GO:0016485 68 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
negative regulation of protein metabolic process GO:0051248 114 0.016
neuron development GO:0048666 286 0.016
regulation of protein maturation GO:1903317 50 0.016
blood circulation GO:0008015 183 0.016
divalent inorganic cation transport GO:0072511 134 0.016
brain development GO:0007420 247 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
rna metabolic process GO:0016070 406 0.016
defense response to gram negative bacterium GO:0050829 3 0.016
cell motility GO:0048870 202 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
forebrain development GO:0030900 98 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
negative regulation of developmental process GO:0051093 125 0.015
nucleotide biosynthetic process GO:0009165 98 0.015
regulation of system process GO:0044057 208 0.015
regulation of nucleotide biosynthetic process GO:0030808 47 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
macromolecule localization GO:0033036 252 0.015
negative regulation of innate immune response GO:0045824 4 0.015
cyclic nucleotide biosynthetic process GO:0009190 63 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.014
sexual reproduction GO:0019953 148 0.014
cellular cation homeostasis GO:0030003 180 0.014
organ induction GO:0001759 1 0.014
establishment of protein localization GO:0045184 141 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
glucose homeostasis GO:0042593 75 0.014
regulation of transferase activity GO:0051338 123 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
gastrulation GO:0007369 2 0.014
negative regulation of cell development GO:0010721 82 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
negative regulation of protein processing GO:0010955 47 0.014
regulation of rna metabolic process GO:0051252 391 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
cell migration GO:0016477 197 0.014
glial cell differentiation GO:0010001 65 0.014
protein heterooligomerization GO:0051291 89 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.013
response to amino acid GO:0043200 75 0.013
mesonephric tubule development GO:0072164 14 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of immune response GO:0050776 55 0.013
regulation of protein processing GO:0070613 50 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
angiogenesis GO:0001525 53 0.013
acute inflammatory response GO:0002526 58 0.013
pallium development GO:0021543 42 0.013
response to ethanol GO:0045471 162 0.013
response to lipopolysaccharide GO:0032496 191 0.013
cellular component movement GO:0006928 248 0.013
cartilage development GO:0051216 22 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
cellular catabolic process GO:0044248 295 0.013
nephron development GO:0072006 22 0.013
fibrinolysis GO:0042730 2 0.013
response to biotic stimulus GO:0009607 226 0.013
cellular response to interleukin 2 GO:0071352 1 0.013
negative regulation of endopeptidase activity GO:0010951 36 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
gland development GO:0048732 155 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.012
developmental induction GO:0031128 2 0.012
regulation of homotypic cell cell adhesion GO:0034110 4 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
regulation of ion transport GO:0043269 245 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
cellular ion homeostasis GO:0006873 184 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
locomotion GO:0040011 237 0.012
mesonephros development GO:0001823 14 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
regulation of protein kinase activity GO:0045859 105 0.012
bmp signaling pathway GO:0030509 4 0.012
camp metabolic process GO:0046058 63 0.012
cellular ketone metabolic process GO:0042180 51 0.012
regulation of cell projection organization GO:0031344 175 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of cell cycle GO:0051726 73 0.012
hormone transport GO:0009914 121 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
negative regulation of response to external stimulus GO:0032102 37 0.012
regulation of proteolysis GO:0030162 66 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
gamete generation GO:0007276 124 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
organ formation GO:0048645 3 0.012
inner ear receptor cell differentiation GO:0060113 2 0.012
regulation of vasculature development GO:1901342 44 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
metal ion homeostasis GO:0055065 186 0.011
neuromuscular process GO:0050905 2 0.011
negative regulation of peptidase activity GO:0010466 38 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
calcium ion homeostasis GO:0055074 162 0.011
cellular response to acid chemical GO:0071229 75 0.011
regulation of secretion GO:0051046 224 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
camp biosynthetic process GO:0006171 47 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
lipid localization GO:0010876 62 0.011
regulation of protein modification process GO:0031399 194 0.011
positive regulation of cyclase activity GO:0031281 15 0.011
organic hydroxy compound transport GO:0015850 77 0.011
organelle organization GO:0006996 266 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
peptidyl amino acid modification GO:0018193 126 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
regulation of kinase activity GO:0043549 117 0.011
lung development GO:0030324 43 0.010
oxidation reduction process GO:0055114 304 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
vesicle mediated transport GO:0016192 181 0.010
localization of cell GO:0051674 202 0.010
metal ion transport GO:0030001 289 0.010
regulation of ras protein signal transduction GO:0046578 45 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
cellular response to oxygen containing compound GO:1901701 386 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
protein maturation GO:0051604 68 0.010
muscle cell proliferation GO:0033002 84 0.010
cell cycle GO:0007049 101 0.010
carboxylic acid metabolic process GO:0019752 289 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.010
amine metabolic process GO:0009308 38 0.010
olfactory bulb interneuron differentiation GO:0021889 1 0.010
regulation of cell motility GO:2000145 131 0.010
taxis GO:0042330 67 0.010
regulation of cyclase activity GO:0031279 21 0.010

Prelp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
musculoskeletal system disease DOID:17 0 0.061
bone disease DOID:0080001 0 0.061
connective tissue disease DOID:65 0 0.061
bone development disease DOID:0080006 0 0.061
nervous system disease DOID:863 0 0.036
osteochondrodysplasia DOID:2256 0 0.012
sensory system disease DOID:0050155 0 0.011