Rattus norvegicus

16 known processes

Prf1

perforin 1 (pore forming protein)

(Aliases: Cyta,RATCYTA,MGC108712)

Prf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.779
Human Mouse
immune response GO:0006955 104 0.775
Mouse
regulation of necroptotic process GO:0060544 2 0.727
cellular response to vitamin k GO:0071307 1 0.482
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.479
positive regulation of immune system process GO:0002684 90 0.321
t helper 1 cell extravasation GO:0035687 1 0.318
regulation of lymphocyte chemotaxis GO:1901623 1 0.310
positive regulation of necroptotic process GO:0060545 2 0.302
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.301
regulation of immune system process GO:0002682 123 0.268
positive regulation of interleukin 1 biosynthetic process GO:0045362 1 0.249
programmed necrotic cell death GO:0097300 2 0.241
response to alkyl hydroperoxide GO:0033195 1 0.217
necroptotic process GO:0070266 2 0.205
helper t cell diapedesis GO:0035685 1 0.205
positive regulation of myeloid leukocyte differentiation GO:0002763 7 0.197
homeostatic process GO:0042592 331 0.193
Rat
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.191
programmed cell death GO:0012501 392 0.173
negative regulation of immune response to tumor cell GO:0002838 2 0.173
positive regulation of cellular biosynthetic process GO:0031328 295 0.172
negative regulation of innate immune response GO:0045824 4 0.172
negative regulation of metabolic process GO:0009892 331 0.163
apoptotic process GO:0006915 381 0.158
regulation of cellular component movement GO:0051270 150 0.155
cellular response to alkyl hydroperoxide GO:0071448 1 0.155
eosinophil migration GO:0072677 3 0.155
positive regulation of gene expression GO:0010628 244 0.151
negative regulation of response to tumor cell GO:0002835 2 0.151
lymphocyte activation GO:0046649 43 0.142
Human
regulation of natural killer cell mediated immunity GO:0002715 6 0.140
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.136
response to reactive oxygen species GO:0000302 120 0.130
positive regulation of necrotic cell death GO:0010940 4 0.130
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.128
positive regulation of t cell migration GO:2000406 1 0.127
regulation of mast cell chemotaxis GO:0060753 1 0.127
response to tumor cell GO:0002347 4 0.124
Mouse
response to interleukin 13 GO:0035962 3 0.117
cell motility GO:0048870 202 0.116
vesicle mediated transport GO:0016192 181 0.116
positive regulation of cell migration GO:0030335 96 0.115
cell activation GO:0001775 97 0.113
Human
interleukin 1 biosynthetic process GO:0042222 1 0.112
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.109
single organism reproductive process GO:0044702 297 0.108
positive regulation of cell motility GO:2000147 97 0.107
taxis GO:0042330 67 0.106
positive regulation of programmed cell death GO:0043068 157 0.106
positive regulation of multicellular organismal process GO:0051240 387 0.105
gland development GO:0048732 155 0.103
interleukin 1 alpha biosynthetic process GO:0050719 1 0.102
response to vitamin k GO:0032571 4 0.101
negative regulation of gene expression GO:0010629 199 0.099
cellular response to endogenous stimulus GO:0071495 377 0.097
leukocyte differentiation GO:0002521 30 0.096
regulation of cell migration GO:0030334 128 0.096
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.096
regulation of neuron death GO:1901214 115 0.092
regulation of rna metabolic process GO:0051252 391 0.090
helper t cell extravasation GO:0035684 1 0.090
aging GO:0007568 241 0.089
negative regulation of cellular metabolic process GO:0031324 281 0.088
hematopoietic or lymphoid organ development GO:0048534 36 0.087
innate immune response GO:0045087 35 0.086
neuron projection development GO:0031175 273 0.085
brain development GO:0007420 247 0.084
response to oxidative stress GO:0006979 186 0.084
response to high density lipoprotein particle GO:0055099 2 0.084
positive regulation of biosynthetic process GO:0009891 319 0.082
positive regulation of transcription dna templated GO:0045893 197 0.079
regulation of myeloid cell differentiation GO:0045637 12 0.077
positive regulation of rna biosynthetic process GO:1902680 197 0.077
enzyme linked receptor protein signaling pathway GO:0007167 116 0.077
response to external biotic stimulus GO:0043207 221 0.077
Mouse
developmental process involved in reproduction GO:0003006 159 0.076
positive regulation of cell death GO:0010942 184 0.075
reproduction GO:0000003 245 0.075
protein oligomerization GO:0051259 191 0.074
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.074
t cell activation GO:0042110 29 0.074
positive regulation of t cell chemotaxis GO:0010820 1 0.074
positive regulation of mast cell chemotaxis GO:0060754 1 0.074
positive regulation of response to stimulus GO:0048584 285 0.073
cellular response to oxidative stress GO:0034599 76 0.072
response to hydrogen peroxide GO:0042542 89 0.072
regulation of neurogenesis GO:0050767 247 0.072
regulation of fever generation GO:0031620 6 0.072
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.072
regulation of t cell chemotaxis GO:0010819 1 0.071
leukocyte activation GO:0045321 76 0.071
Human
regulation of locomotion GO:0040012 148 0.071
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.070
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.070
immune system development GO:0002520 41 0.069
organophosphate metabolic process GO:0019637 370 0.069
positive regulation of nucleic acid templated transcription GO:1903508 197 0.069
positive regulation of locomotion GO:0040017 102 0.068
rna biosynthetic process GO:0032774 380 0.067
inflammatory response GO:0006954 150 0.067
regulation of signal transduction GO:0009966 318 0.067
regulation of defense response GO:0031347 68 0.066
regulation of programmed cell death GO:0043067 341 0.066
positive regulation of fever generation GO:0031622 5 0.065
salivary gland development GO:0007431 3 0.065
natural killer cell mediated cytotoxicity GO:0042267 6 0.065
tissue development GO:0009888 252 0.065
cytokine biosynthetic process GO:0042089 3 0.064
cellular component biogenesis GO:0044085 368 0.064
Human Mouse
diapedesis GO:0050904 1 0.064
mast cell migration GO:0097531 4 0.064
positive regulation of cellular component movement GO:0051272 102 0.063
cell type specific apoptotic process GO:0097285 134 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.061
response to growth factor GO:0070848 189 0.060
cell projection organization GO:0030030 302 0.060
negative regulation of multicellular organismal process GO:0051241 203 0.060
cytoskeleton organization GO:0007010 111 0.060
temperature homeostasis GO:0001659 17 0.058
cellular response to lipoteichoic acid GO:0071223 1 0.058
leukocyte cell cell adhesion GO:0007159 4 0.058
myeloid leukocyte differentiation GO:0002573 20 0.057
positive regulation of smooth muscle cell migration GO:0014911 27 0.057
response to biotic stimulus GO:0009607 226 0.056
Mouse
response to extracellular stimulus GO:0009991 380 0.056
t cell extravasation GO:0072683 1 0.054
reproductive process GO:0022414 372 0.054
localization of cell GO:0051674 202 0.053
locomotion GO:0040011 237 0.053
cell activation involved in immune response GO:0002263 16 0.053
response to ammonium ion GO:0060359 71 0.052
cell part morphogenesis GO:0032990 123 0.052
regulation of natural killer cell mediated cytotoxicity GO:0042269 6 0.052
defense response GO:0006952 194 0.052
Mouse
sequestering of metal ion GO:0051238 9 0.052
transcription dna templated GO:0006351 377 0.052
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.052
cellular component movement GO:0006928 248 0.051
positive regulation of cell proliferation GO:0008284 249 0.051
cell chemotaxis GO:0060326 31 0.050
pseudopodium assembly GO:0031269 3 0.050
nucleobase containing small molecule metabolic process GO:0055086 316 0.049
gonad development GO:0008406 104 0.049
cellular biogenic amine metabolic process GO:0006576 30 0.049
actin cytoskeleton organization GO:0030036 73 0.049
leukocyte mediated immunity GO:0002443 28 0.049
behavior GO:0007610 205 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.047
positive regulation of leukocyte differentiation GO:1902107 13 0.047
positive regulation of immune response GO:0050778 42 0.047
oxoacid metabolic process GO:0043436 290 0.047
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 2 0.046
ion homeostasis GO:0050801 212 0.046
Rat
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.045
phosphatidylcholine metabolic process GO:0046470 10 0.045
protein phosphorylation GO:0006468 345 0.045
growth GO:0040007 165 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
positive regulation of apoptotic process GO:0043065 154 0.044
single organism organelle organization GO:1902589 180 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
negative regulation of response to stimulus GO:0048585 155 0.043
cellular response to growth factor stimulus GO:0071363 162 0.043
positive regulation of nervous system development GO:0051962 178 0.043
positive regulation of defense response GO:0031349 37 0.043
acute phase response GO:0006953 20 0.043
regulation of interleukin 1 alpha production GO:0032650 1 0.043
neuron projection morphogenesis GO:0048812 122 0.042
peptidyl tyrosine phosphorylation GO:0018108 72 0.042
rna metabolic process GO:0016070 406 0.042
muscle cell proliferation GO:0033002 84 0.042
cellular metal ion homeostasis GO:0006875 172 0.042
Rat
response to corticosteroid GO:0031960 235 0.042
circulatory system process GO:0003013 183 0.042
regulation of neuron differentiation GO:0045664 208 0.041
neurological system process GO:0050877 219 0.041
cellular response to stress GO:0033554 269 0.041
cell adhesion GO:0007155 110 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
Human Mouse
sexual reproduction GO:0019953 148 0.040
t helper 1 cell diapedesis GO:0035688 1 0.040
cell migration GO:0016477 197 0.040
cellular response to oxygen containing compound GO:1901701 386 0.040
sex differentiation GO:0007548 113 0.040
amine metabolic process GO:0009308 38 0.040
biological adhesion GO:0022610 110 0.040
muscle tissue development GO:0060537 58 0.039
organ morphogenesis GO:0009887 75 0.039
hemopoiesis GO:0030097 34 0.039
epithelium development GO:0060429 96 0.039
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.038
immune effector process GO:0002252 53 0.038
Mouse
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.038
cellular amine metabolic process GO:0044106 38 0.038
regulation of cytokine biosynthetic process GO:0042035 3 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
phospholipid metabolic process GO:0006644 61 0.038
central nervous system development GO:0007417 311 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
regulation of response to stress GO:0080134 126 0.037
regulation of response to wounding GO:1903034 69 0.037
negative regulation of cell death GO:0060548 229 0.037
regulation of lymphocyte migration GO:2000401 1 0.037
liver development GO:0001889 90 0.037
response to fatty acid GO:0070542 65 0.037
osteoclast differentiation GO:0030316 11 0.037
cell killing GO:0001906 13 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.037
exploration behavior GO:0035640 1 0.036
positive regulation of homeostatic process GO:0032846 49 0.036
response to wounding GO:0009611 254 0.036
positive regulation of developmental process GO:0051094 283 0.036
regulation of nervous system development GO:0051960 264 0.036
hormone transport GO:0009914 121 0.036
divalent inorganic cation homeostasis GO:0072507 165 0.036
cellular response to molecule of bacterial origin GO:0071219 56 0.036
regulation of phosphate metabolic process GO:0019220 349 0.035
t cell receptor signaling pathway GO:0050852 1 0.035
proteolysis GO:0006508 175 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
chemical homeostasis GO:0048878 292 0.035
Rat
circulatory system development GO:0072359 134 0.034
regulation of cell killing GO:0031341 12 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.034
fever generation GO:0001660 9 0.034
cellular amino acid metabolic process GO:0006520 107 0.033
regulation of immune response to tumor cell GO:0002837 3 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.032
g protein coupled receptor signaling pathway GO:0007186 242 0.032
neuron differentiation GO:0030182 368 0.032
intracellular signal transduction GO:0035556 314 0.032
regulation of hydrolase activity GO:0051336 143 0.032
single organism cell adhesion GO:0098602 46 0.032
regulation of cellular component organization GO:0051128 368 0.032
t cell chemotaxis GO:0010818 2 0.032
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 8 0.031
purine containing compound metabolic process GO:0072521 253 0.031
interleukin 1 alpha production GO:0032610 1 0.031
chemotaxis GO:0006935 66 0.031
synaptic growth at neuromuscular junction GO:0051124 1 0.031
response to decreased oxygen levels GO:0036293 237 0.031
cellular response to lipid GO:0071396 201 0.030
cellular response to cytokine stimulus GO:0071345 127 0.030
gliogenesis GO:0042063 93 0.030
single organismal cell cell adhesion GO:0016337 42 0.030
response to nutrient levels GO:0031667 370 0.030
cellular response to organic cyclic compound GO:0071407 202 0.029
single organism cellular localization GO:1902580 102 0.029
nucleic acid templated transcription GO:0097659 379 0.029
endocytosis GO:0006897 84 0.029
cellular response to ammonium ion GO:0071242 17 0.029
regulation of stem cell differentiation GO:2000736 2 0.029
positive regulation of response to wounding GO:1903036 34 0.029
regulation of cell motility GO:2000145 131 0.029
exocytosis GO:0006887 60 0.029
response to hypoxia GO:0001666 231 0.028
positive regulation of neuron differentiation GO:0045666 126 0.028
t cell migration GO:0072678 2 0.028
organelle organization GO:0006996 266 0.028
regulation of cell development GO:0060284 263 0.028
regulation of leukocyte mediated immunity GO:0002703 19 0.028
regulation of apoptotic process GO:0042981 335 0.027
positive regulation of cytokine biosynthetic process GO:0042108 1 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
regulation of response to tumor cell GO:0002834 3 0.027
sensory perception of pain GO:0019233 73 0.027
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 14 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.027
vasculature development GO:0001944 70 0.026
myeloid leukocyte activation GO:0002274 36 0.026
cation homeostasis GO:0055080 195 0.026
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.026
phosphatidylinositol 3 kinase signaling GO:0014065 14 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
neuron development GO:0048666 286 0.026
regulation of muscle contraction GO:0006937 53 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.026
immune response regulating signaling pathway GO:0002764 19 0.025
cellular chemical homeostasis GO:0055082 247 0.025
Rat
response to acid chemical GO:0001101 222 0.025
regulation of leukocyte mediated cytotoxicity GO:0001910 10 0.025
nucleotide metabolic process GO:0009117 279 0.025
regulation of cell projection organization GO:0031344 175 0.025
negative regulation of cell differentiation GO:0045596 99 0.025
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
mast cell chemotaxis GO:0002551 4 0.025
positive regulation of protein modification process GO:0031401 142 0.024
myeloid cell differentiation GO:0030099 22 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
regulation of smooth muscle cell proliferation GO:0048660 75 0.024
salivary gland morphogenesis GO:0007435 1 0.024
positive regulation of leukocyte activation GO:0002696 30 0.024
response to nutrient GO:0007584 248 0.024
regulation of response to external stimulus GO:0032101 106 0.024
regulation of interleukin 1 biosynthetic process GO:0045360 1 0.024
regulation of inflammatory response GO:0050727 48 0.024
regulatory t cell differentiation GO:0045066 2 0.023
regulation of regulatory t cell differentiation GO:0045589 2 0.023
positive regulation of chemotaxis GO:0050921 23 0.023
cellular response to hydroperoxide GO:0071447 2 0.023
cellular component morphogenesis GO:0032989 155 0.023
positive regulation of heat generation GO:0031652 7 0.023
regulation of phagocytosis engulfment GO:0060099 4 0.023
protein autophosphorylation GO:0046777 66 0.023
response to radiation GO:0009314 137 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
regulation of body fluid levels GO:0050878 90 0.022
positive regulation of inflammatory response GO:0050729 24 0.022
regulation of immune response GO:0050776 55 0.022
renal system development GO:0072001 67 0.022
motor neuron axon guidance GO:0008045 1 0.022
smooth muscle cell proliferation GO:0048659 77 0.022
response to axon injury GO:0048678 59 0.022
cellular response to nitrogen compound GO:1901699 210 0.021
regulation of cell proliferation GO:0042127 359 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
oligopeptide transport GO:0006857 4 0.021
cell cell junction organization GO:0045216 20 0.021
cellular response to lipopolysaccharide GO:0071222 55 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
mesoderm development GO:0007498 2 0.021
regulation of protein metabolic process GO:0051246 289 0.021
cellular ion homeostasis GO:0006873 184 0.021
Rat
positive regulation of response to external stimulus GO:0032103 51 0.021
regulation of macrophage chemotaxis GO:0010758 2 0.021
actin filament based process GO:0030029 86 0.021
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 13 0.020
developmental growth GO:0048589 100 0.020
regulation of t cell migration GO:2000404 1 0.020
rhythmic process GO:0048511 156 0.020
cellular response to reactive oxygen species GO:0034614 55 0.020
regulation of cell differentiation GO:0045595 320 0.020
regulation of molecular function GO:0065009 398 0.020
defense response to gram positive bacterium GO:0050830 2 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
negative regulation of signaling GO:0023057 157 0.020
anterior posterior pattern specification GO:0009952 1 0.020
multi organism reproductive process GO:0044703 262 0.020
development of primary female sexual characteristics GO:0046545 56 0.020
natural killer cell mediated immunity GO:0002228 6 0.020
positive regulation of cell development GO:0010720 176 0.020
reproductive structure development GO:0048608 128 0.020
cellular response to ketone GO:1901655 51 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
formation of primary germ layer GO:0001704 1 0.020
t cell tolerance induction GO:0002517 3 0.019
response to peptide hormone GO:0043434 278 0.019
regeneration GO:0031099 163 0.019
multicellular organismal homeostasis GO:0048871 49 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of hydrolase activity GO:0051345 86 0.019
negative regulation of leukocyte mediated immunity GO:0002704 6 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.019
intracellular transport GO:0046907 185 0.019
regulation of leukocyte activation GO:0002694 45 0.019
negative regulation of nervous system development GO:0051961 79 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
locomotory exploration behavior GO:0035641 1 0.018
response to cytokine GO:0034097 215 0.018
nucleoside metabolic process GO:0009116 179 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
protein complex subunit organization GO:0071822 302 0.018
Human Mouse
neuron death GO:0070997 127 0.018
transmembrane transport GO:0055085 412 0.018
Human Mouse
cellular component assembly GO:0022607 360 0.018
Human Mouse
actin filament organization GO:0007015 42 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
regulation of transcription dna templated GO:0006355 374 0.018
regulation of immunoglobulin production GO:0002637 4 0.018
ion transmembrane transport GO:0034220 365 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
regulation of cell activation GO:0050865 50 0.018
cell junction organization GO:0034330 21 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
cell substrate adhesion GO:0031589 29 0.017
positive regulation of transport GO:0051050 245 0.017
negative regulation of calcium ion import GO:0090281 2 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
response to purine containing compound GO:0014074 126 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
multicellular organism reproduction GO:0032504 233 0.017
activation of immune response GO:0002253 26 0.017
peptidyl amino acid modification GO:0018193 126 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
negative regulation of viral process GO:0048525 4 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
regulation of interleukin 1 alpha biosynthetic process GO:0050721 1 0.017
mast cell activation involved in immune response GO:0002279 10 0.017
positive regulation of natural killer cell mediated immunity GO:0002717 2 0.017
development of primary sexual characteristics GO:0045137 107 0.017
negative regulation of developmental process GO:0051093 125 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
response to sterol GO:0036314 13 0.016
positive regulation of interleukin 1 alpha production GO:0032730 1 0.016
striated muscle tissue development GO:0014706 58 0.016
response to ketone GO:1901654 182 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
regulation of ion transport GO:0043269 245 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
sequestering of calcium ion GO:0051208 8 0.016
ethanolamine containing compound metabolic process GO:0042439 14 0.016
lymphocyte chemotaxis GO:0048247 3 0.016
smooth muscle cell migration GO:0014909 36 0.016
positive regulation of homotypic cell cell adhesion GO:0034112 2 0.016
negative regulation of molecular function GO:0044092 133 0.016
immunoglobulin mediated immune response GO:0016064 4 0.016
cytokine mediated signaling pathway GO:0019221 43 0.016
blood circulation GO:0008015 183 0.016
female sex differentiation GO:0046660 59 0.016
positive regulation of cell communication GO:0010647 271 0.016
regulation of smooth muscle cell migration GO:0014910 36 0.016
cell cell signaling GO:0007267 335 0.016
skin morphogenesis GO:0043589 2 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
nitrogen compound transport GO:0071705 229 0.015
positive regulation of myeloid cell differentiation GO:0045639 7 0.015
muscle organ development GO:0007517 50 0.015
positive regulation of behavior GO:0048520 38 0.015
positive regulation of osteoclast differentiation GO:0045672 5 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
leukocyte activation involved in immune response GO:0002366 16 0.015
regulation of innate immune response GO:0045088 15 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
response to oxygen levels GO:0070482 265 0.015
response to carbohydrate GO:0009743 183 0.015
response to estrogen GO:0043627 232 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
reproductive system development GO:0061458 128 0.015
alpha beta t cell activation GO:0046631 3 0.015
regulation of behavior GO:0050795 61 0.015
organic cyclic compound catabolic process GO:1901361 175 0.014
cell matrix adhesion GO:0007160 19 0.014
head development GO:0060322 247 0.014
metal ion homeostasis GO:0055065 186 0.014
Rat
amide transport GO:0042886 105 0.014
autophagic cell death GO:0048102 4 0.014
macromolecular complex assembly GO:0065003 273 0.014
Human Mouse
regulation of neuron projection development GO:0010975 161 0.014
anatomical structure homeostasis GO:0060249 29 0.014
neuron apoptotic process GO:0051402 88 0.014
b cell mediated immunity GO:0019724 4 0.014
regulation of cell cycle GO:0051726 73 0.014
regulation of monocyte chemotaxis GO:0090025 3 0.014
macromolecule localization GO:0033036 252 0.014
antigen receptor mediated signaling pathway GO:0050851 1 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
gamete generation GO:0007276 124 0.014
ovulation cycle GO:0042698 67 0.014
spindle organization GO:0007051 2 0.014
cell junction assembly GO:0034329 18 0.014
bmp signaling pathway GO:0030509 4 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
negative regulation of immune system process GO:0002683 39 0.014
negative regulation of cell development GO:0010721 82 0.014
cell cycle GO:0007049 101 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
positive regulation of isotype switching to igg isotypes GO:0048304 1 0.014
immune response to tumor cell GO:0002418 3 0.014
Mouse
ras protein signal transduction GO:0007265 29 0.014
regulation of lymphocyte mediated immunity GO:0002706 11 0.014
response to glucocorticoid GO:0051384 223 0.014
organ formation GO:0048645 3 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
single organism biosynthetic process GO:0044711 342 0.013
response to lipoteichoic acid GO:0070391 1 0.013
positive regulation of mast cell activation GO:0033005 4 0.013
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.013
response to transforming growth factor beta GO:0071559 46 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
dendrite development GO:0016358 72 0.013
regulation of proteolysis GO:0030162 66 0.013
regulation of heat generation GO:0031650 8 0.013
muscle cell migration GO:0014812 36 0.013
response to other organism GO:0051707 220 0.013
Mouse
nucleoside monophosphate metabolic process GO:0009123 93 0.013
cytokine metabolic process GO:0042107 6 0.013
regulation of immune effector process GO:0002697 32 0.013
cellular response to high density lipoprotein particle stimulus GO:0071403 2 0.013
male gonad development GO:0008584 59 0.013
response to tumor necrosis factor GO:0034612 56 0.013
regulation of homotypic cell cell adhesion GO:0034110 4 0.013

Prf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.080
Human
connective tissue disease DOID:65 0 0.080
musculoskeletal system disease DOID:17 0 0.080
bone disease DOID:0080001 0 0.026