Rattus norvegicus

0 known processes

Prkab2

protein kinase, AMP-activated, beta 2 non-catalytic subunit

(Aliases: MGC93432)

Prkab2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.214
programmed cell death GO:0012501 392 0.177
protein phosphorylation GO:0006468 345 0.169
Human Yeast Rat
negative regulation of apoptotic process GO:0043066 181 0.158
regulation of molecular function GO:0065009 398 0.155
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.135
positive regulation of cell proliferation GO:0008284 249 0.121
single organism intracellular transport GO:1902582 166 0.118
regulation of metal ion transport GO:0010959 118 0.115
regulation of programmed cell death GO:0043067 341 0.112
positive regulation of response to stimulus GO:0048584 285 0.103
ion homeostasis GO:0050801 212 0.101
response to decreased oxygen levels GO:0036293 237 0.098
behavior GO:0007610 205 0.097
regulation of nucleic acid templated transcription GO:1903506 380 0.096
cell cell signaling GO:0007267 335 0.096
rna metabolic process GO:0016070 406 0.088
single organism reproductive process GO:0044702 297 0.087
enzyme linked receptor protein signaling pathway GO:0007167 116 0.086
intracellular signal transduction GO:0035556 314 0.085
regulation of cellular localization GO:0060341 263 0.084
cation homeostasis GO:0055080 195 0.083
cellular response to endogenous stimulus GO:0071495 377 0.081
muscle structure development GO:0061061 87 0.080
cellular component movement GO:0006928 248 0.077
metal ion transport GO:0030001 289 0.076
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.075
regulation of cell proliferation GO:0042127 359 0.075
regulation of signal transduction GO:0009966 318 0.073
regulation of anatomical structure morphogenesis GO:0022603 141 0.071
rhythmic process GO:0048511 156 0.069
regulation of protein phosphorylation GO:0001932 183 0.068
metal ion homeostasis GO:0055065 186 0.068
reproductive system development GO:0061458 128 0.067
regulation of intracellular signal transduction GO:1902531 218 0.067
chemical homeostasis GO:0048878 292 0.067
regulation of multicellular organismal development GO:2000026 376 0.065
negative regulation of metabolic process GO:0009892 331 0.059
regulation of cellular protein metabolic process GO:0032268 267 0.058
regulation of protein metabolic process GO:0051246 289 0.058
blood vessel development GO:0001568 69 0.058
regulation of membrane potential GO:0042391 110 0.057
central nervous system development GO:0007417 311 0.057
tissue development GO:0009888 252 0.056
calcium ion transport GO:0006816 131 0.056
regulation of homeostatic process GO:0032844 101 0.056
cellular response to nitrogen compound GO:1901699 210 0.055
positive regulation of molecular function GO:0044093 230 0.055
response to estradiol GO:0032355 164 0.054
cellular ion homeostasis GO:0006873 184 0.054
rna biosynthetic process GO:0032774 380 0.054
macromolecule localization GO:0033036 252 0.053
nucleic acid templated transcription GO:0097659 379 0.053
regulation of rna metabolic process GO:0051252 391 0.052
macromolecular complex assembly GO:0065003 273 0.052
Yeast Rat
divalent inorganic cation transport GO:0072511 134 0.052
sensory perception of pain GO:0019233 73 0.052
apoptotic process GO:0006915 381 0.050
growth GO:0040007 165 0.049
Yeast
homeostatic process GO:0042592 331 0.049
signal transduction by phosphorylation GO:0023014 144 0.048
reproductive process GO:0022414 372 0.048
negative regulation of macromolecule metabolic process GO:0010605 260 0.048
positive regulation of phosphate metabolic process GO:0045937 262 0.048
regulation of locomotion GO:0040012 148 0.048
cell morphogenesis involved in differentiation GO:0000904 119 0.047
cellular homeostasis GO:0019725 252 0.047
developmental process involved in reproduction GO:0003006 159 0.046
negative regulation of multicellular organismal process GO:0051241 203 0.046
organic substance catabolic process GO:1901575 316 0.045
cellular cation homeostasis GO:0030003 180 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.045
regulation of cellular component movement GO:0051270 150 0.045
response to growth factor GO:0070848 189 0.044
positive regulation of biosynthetic process GO:0009891 319 0.044
immune system process GO:0002376 204 0.043
transmission of nerve impulse GO:0019226 42 0.043
ribonucleotide metabolic process GO:0009259 231 0.043
sequestering of calcium ion GO:0051208 8 0.043
transcription dna templated GO:0006351 377 0.042
positive regulation of signal transduction GO:0009967 175 0.042
regulation of cellular component organization GO:0051128 368 0.042
Yeast
protein complex subunit organization GO:0071822 302 0.041
Yeast Rat
intracellular transport GO:0046907 185 0.041
regulation of growth GO:0040008 105 0.041
response to glucocorticoid GO:0051384 223 0.041
regulation of cell growth GO:0001558 85 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.040
regulation of ion homeostasis GO:2000021 63 0.040
negative regulation of phosphorus metabolic process GO:0010563 80 0.040
regulation of phosphate metabolic process GO:0019220 349 0.040
reproductive structure development GO:0048608 128 0.040
positive regulation of developmental process GO:0051094 283 0.040
peptidyl tyrosine modification GO:0018212 72 0.039
gonad development GO:0008406 104 0.039
protein localization GO:0008104 191 0.039
regulation of apoptotic process GO:0042981 335 0.038
calcium ion homeostasis GO:0055074 162 0.038
mapk cascade GO:0000165 140 0.038
regulation of transferase activity GO:0051338 123 0.038
amine metabolic process GO:0009308 38 0.037
positive regulation of signaling GO:0023056 270 0.037
secretion GO:0046903 307 0.036
divalent metal ion transport GO:0070838 132 0.036
cellular component morphogenesis GO:0032989 155 0.036
sex differentiation GO:0007548 113 0.036
cellular metal ion homeostasis GO:0006875 172 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
protein complex assembly GO:0006461 263 0.036
Yeast Rat
cellular component assembly GO:0022607 360 0.036
Yeast Rat
cytoplasmic transport GO:0016482 115 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
chemotaxis GO:0006935 66 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
divalent inorganic cation homeostasis GO:0072507 165 0.035
sexual reproduction GO:0019953 148 0.035
negative regulation of programmed cell death GO:0043069 183 0.034
cellular amine metabolic process GO:0044106 38 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
intracellular protein transport GO:0006886 79 0.034
negative regulation of transport GO:0051051 136 0.034
neurological system process GO:0050877 219 0.034
cellular chemical homeostasis GO:0055082 247 0.033
regulation of cell development GO:0060284 263 0.033
negative regulation of cell death GO:0060548 229 0.033
negative regulation of protein phosphorylation GO:0001933 44 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
regulation of protein kinase activity GO:0045859 105 0.032
multi organism reproductive process GO:0044703 262 0.031
ion transmembrane transport GO:0034220 365 0.031
regulation of transcription dna templated GO:0006355 374 0.031
establishment of protein localization GO:0045184 141 0.031
regulation of cell morphogenesis GO:0022604 77 0.030
nucleotide metabolic process GO:0009117 279 0.030
response to hypoxia GO:0001666 231 0.030
cell migration GO:0016477 197 0.030
response to estrogen GO:0043627 232 0.029
regulation of phosphorylation GO:0042325 248 0.029
multicellular organismal signaling GO:0035637 44 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
neuron projection morphogenesis GO:0048812 122 0.028
motor neuron axon guidance GO:0008045 1 0.028
single organism cellular localization GO:1902580 102 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
negative regulation of protein metabolic process GO:0051248 114 0.028
regulation of behavior GO:0050795 61 0.028
ribose phosphate metabolic process GO:0019693 235 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
response to cytokine GO:0034097 215 0.027
positive regulation of behavior GO:0048520 38 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
response to wounding GO:0009611 254 0.026
neuron death GO:0070997 127 0.026
regulation of calcium ion transport GO:0051924 77 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
response to temperature stimulus GO:0009266 94 0.025
neuromuscular process GO:0050905 2 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
cell part morphogenesis GO:0032990 123 0.025
regulation of cell differentiation GO:0045595 320 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
negative regulation of signaling GO:0023057 157 0.024
regulation of muscle system process GO:0090257 79 0.024
neuron differentiation GO:0030182 368 0.024
development of primary sexual characteristics GO:0045137 107 0.024
regulation of purine nucleotide metabolic process GO:1900542 115 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.024
regulation of mapk cascade GO:0043408 116 0.024
monovalent inorganic cation transport GO:0015672 172 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
transmembrane transport GO:0055085 412 0.024
positive regulation of mapk cascade GO:0043410 92 0.024
negative regulation of gene expression GO:0010629 199 0.023
regulation of organ formation GO:0003156 2 0.023
cell motility GO:0048870 202 0.023
organ formation GO:0048645 3 0.023
cellular ketone metabolic process GO:0042180 51 0.023
female pregnancy GO:0007565 122 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
calcium ion transport into cytosol GO:0060402 38 0.023
regulation of catalytic activity GO:0050790 304 0.023
Rat
neuron development GO:0048666 286 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
regulation of protein modification process GO:0031399 194 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
regulation of transporter activity GO:0032409 50 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
regulation of neurological system process GO:0031644 43 0.022
regulation of sodium ion transport GO:0002028 21 0.022
locomotion GO:0040011 237 0.022
multicellular organism reproduction GO:0032504 233 0.022
cell morphogenesis GO:0000902 142 0.022
neuron projection development GO:0031175 273 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
cell projection morphogenesis GO:0048858 123 0.021
regulation of neuron projection development GO:0010975 161 0.021
single organism behavior GO:0044708 130 0.021
response to oxygen levels GO:0070482 265 0.021
feeding behavior GO:0007631 53 0.021
response to nutrient levels GO:0031667 370 0.020
inflammatory response GO:0006954 150 0.020
taxis GO:0042330 67 0.020
reproduction GO:0000003 245 0.020
negative regulation of cell communication GO:0010648 158 0.020
positive regulation of kinase activity GO:0033674 77 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
regulation of cell projection organization GO:0031344 175 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
sequestering of metal ion GO:0051238 9 0.020
multi multicellular organism process GO:0044706 138 0.020
purine ribonucleotide biosynthetic process GO:0009152 81 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
inorganic ion transmembrane transport GO:0098660 229 0.019
peptidyl tyrosine phosphorylation GO:0018108 72 0.019
protein targeting GO:0006605 61 0.019
cation transport GO:0006812 382 0.019
calcium ion transmembrane transport GO:0070588 70 0.019
secretion by cell GO:0032940 248 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
brain development GO:0007420 247 0.019
organophosphate metabolic process GO:0019637 370 0.019
neuron fate commitment GO:0048663 4 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
protein autophosphorylation GO:0046777 66 0.019
synaptic transmission GO:0007268 235 0.018
regulation of nervous system development GO:0051960 264 0.018
regulation of axonogenesis GO:0050770 37 0.018
hormone transport GO:0009914 121 0.018
positive regulation of protein modification process GO:0031401 142 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
axon development GO:0061564 96 0.018
axis specification GO:0009798 4 0.018
response to ethanol GO:0045471 162 0.018
cell growth GO:0016049 104 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
negative regulation of secretion GO:0051048 82 0.018
localization of cell GO:0051674 202 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
regulation of hormone levels GO:0010817 187 0.018
action potential GO:0001508 54 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
sensory perception GO:0007600 101 0.018
sodium ion homeostasis GO:0055078 23 0.017
protein transport GO:0015031 132 0.017
negative regulation of phosphorylation GO:0042326 57 0.017
excretion GO:0007588 24 0.017
positive regulation of protein kinase activity GO:0045860 73 0.017
regulation of ion transport GO:0043269 245 0.017
muscle cell proliferation GO:0033002 84 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
Yeast Rat
cellular macromolecule localization GO:0070727 122 0.017
tube development GO:0035295 89 0.017
cytosolic calcium ion transport GO:0060401 39 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
regulation of response to external stimulus GO:0032101 106 0.017
striated muscle tissue development GO:0014706 58 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
negative regulation of protein modification process GO:0031400 52 0.016
peptidyl amino acid modification GO:0018193 126 0.016
synapse organization GO:0050808 46 0.016
mesoderm development GO:0007498 2 0.016
ras protein signal transduction GO:0007265 29 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
gastrulation GO:0007369 2 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
regulation of kinase activity GO:0043549 117 0.016
circulatory system development GO:0072359 134 0.016
anterior posterior pattern specification GO:0009952 1 0.015
regulation of ion transmembrane transporter activity GO:0032412 48 0.015
wound healing GO:0042060 122 0.015
positive regulation of cell communication GO:0010647 271 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
regulation of neuron differentiation GO:0045664 208 0.015
nucleotide biosynthetic process GO:0009165 98 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
renal sodium excretion GO:0035812 20 0.015
negative regulation of developmental process GO:0051093 125 0.015
positive regulation of transcription dna templated GO:0045893 197 0.014
response to oxidative stress GO:0006979 186 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
regeneration GO:0031099 163 0.014
positive regulation of cell death GO:0010942 184 0.014
developmental induction GO:0031128 2 0.014
regulation of cell motility GO:2000145 131 0.014
hormone secretion GO:0046879 115 0.014
purine containing compound metabolic process GO:0072521 253 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
neuronal action potential GO:0019228 35 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
positive regulation of programmed cell death GO:0043068 157 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
vesicle mediated transport GO:0016192 181 0.013
protein complex biogenesis GO:0070271 263 0.013
Yeast Rat
cell cycle GO:0007049 101 0.013
endocytosis GO:0006897 84 0.013
protein localization to organelle GO:0033365 57 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
developmental growth GO:0048589 100 0.013
cellular component biogenesis GO:0044085 368 0.013
Yeast Rat
cellular calcium ion homeostasis GO:0006874 160 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
response to blue light GO:0009637 1 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of epithelial cell proliferation GO:0050678 49 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
negative regulation of signal transduction GO:0009968 83 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
gamete generation GO:0007276 124 0.012
epithelial cell differentiation GO:0030855 71 0.012
organ induction GO:0001759 1 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
defense response GO:0006952 194 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
intracellular receptor signaling pathway GO:0030522 35 0.012
negative regulation of molecular function GO:0044092 133 0.012
lipid biosynthetic process GO:0008610 128 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of neurogenesis GO:0050767 247 0.012
somatostatin receptor signaling pathway GO:0038169 4 0.012
axonogenesis GO:0007409 71 0.012
muscle organ development GO:0007517 50 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
cell projection organization GO:0030030 302 0.012
second messenger mediated signaling GO:0019932 51 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
regulation of cell migration GO:0030334 128 0.012
heterocycle catabolic process GO:0046700 167 0.012
positive regulation of gene expression GO:0010628 244 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
regulation of receptor activity GO:0010469 29 0.011
response to nutrient GO:0007584 248 0.011
male sex differentiation GO:0046661 64 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
regulation of hydrolase activity GO:0051336 143 0.011
cellular protein localization GO:0034613 122 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
response to extracellular stimulus GO:0009991 380 0.011
gtp metabolic process GO:0046039 72 0.011
macromolecule catabolic process GO:0009057 58 0.011
nuclear transport GO:0051169 49 0.011
response to biotic stimulus GO:0009607 226 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
dephosphorylation GO:0016311 98 0.011
embryonic pattern specification GO:0009880 1 0.011
cellular response to stress GO:0033554 269 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
head development GO:0060322 247 0.011
male gamete generation GO:0048232 99 0.011
gland development GO:0048732 155 0.011
protein localization to nucleus GO:0034504 39 0.011
camp metabolic process GO:0046058 63 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
regulation of intracellular transport GO:0032386 65 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
membrane depolarization GO:0051899 32 0.010
regulation of muscle contraction GO:0006937 53 0.010
proteolysis GO:0006508 175 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
coronary vasculature morphogenesis GO:0060977 3 0.010
lipid transport GO:0006869 61 0.010
muscle tissue development GO:0060537 58 0.010
vasculature development GO:0001944 70 0.010
organelle organization GO:0006996 266 0.010
development of primary female sexual characteristics GO:0046545 56 0.010
epithelial cell proliferation GO:0050673 54 0.010
muscle system process GO:0003012 115 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010

Prkab2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.025
disease of anatomical entity DOID:7 0 0.025
central nervous system disease DOID:331 0 0.020
endocrine system disease DOID:28 0 0.012
cancer DOID:162 0 0.011
colon carcinoma DOID:1520 0 0.011
large intestine cancer DOID:5672 0 0.011
colon cancer DOID:219 0 0.011
intestinal cancer DOID:10155 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
organ system cancer DOID:0050686 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
colorectal cancer DOID:9256 0 0.011
disease of metabolism DOID:0014667 0 0.011