|
|
stress activated mapk cascade
|
GO:0051403 |
35 |
0.567
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
8 |
0.387
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
10 |
0.356
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.341
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.329
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.303
|
Fly |
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.240
|
Fly |
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.234
|
Mouse Fly |
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.227
|
Fly |
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.224
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.217
|
Yeast Fly |
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.215
|
|
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.208
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.208
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.206
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.193
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.192
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.190
|
Yeast Fly |
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.183
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.183
|
Worm |
|
|
apoptotic process
|
GO:0006915 |
381 |
0.174
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
37 |
0.167
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.163
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.162
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.161
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.158
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
1 |
0.155
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.154
|
Fly |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.153
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.151
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.150
|
Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.148
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.148
|
Fly |
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.148
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.147
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.145
|
|
|
|
male mating behavior
|
GO:0060179 |
3 |
0.145
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.144
|
Rat Fly |
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.143
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.139
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
23 |
0.137
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.134
|
Fly |
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.131
|
Fly |
|
|
response to metal ion
|
GO:0010038 |
253 |
0.129
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.129
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.129
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.121
|
Fly |
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.121
|
|
|
|
jnk cascade
|
GO:0007254 |
28 |
0.120
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.120
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.120
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.120
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
1 |
0.115
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
2 |
0.115
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.115
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.115
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.114
|
|
|
|
lymphocyte migration
|
GO:0072676 |
3 |
0.113
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.112
|
|
|
|
epiboly
|
GO:0090504 |
2 |
0.112
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.112
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.111
|
Rat Fly |
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.111
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.110
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.110
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.107
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.106
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.106
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.104
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.103
|
|
|
|
response to heat
|
GO:0009408 |
60 |
0.102
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.100
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.097
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.097
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
59 |
0.095
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.093
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.092
|
Fly |
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.092
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.092
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.090
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.090
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.090
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.089
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.088
|
|
|
|
prostaglandin secretion
|
GO:0032310 |
6 |
0.088
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.088
|
Rat Fly |
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.087
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.087
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.086
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.086
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.085
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.085
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.084
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.084
|
Mouse Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.083
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.083
|
Worm |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.081
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.081
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.081
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.080
|
Mouse Fly |
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.079
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.079
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.079
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.079
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.079
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.078
|
|
|
|
cytokine production
|
GO:0001816 |
61 |
0.078
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.077
|
Worm |
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
38 |
0.077
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.076
|
|
|
|
vesicle fusion with golgi apparatus
|
GO:0048280 |
4 |
0.076
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.075
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.075
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
83 |
0.075
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.074
|
|
|
|
positive regulation of dendritic spine development
|
GO:0060999 |
9 |
0.074
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.074
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.073
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.073
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
152 |
0.073
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.073
|
|
|
|
jun phosphorylation
|
GO:0007258 |
12 |
0.072
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
33 |
0.072
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.070
|
|
|
|
aging
|
GO:0007568 |
241 |
0.069
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.069
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.069
|
Mouse |
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.069
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.069
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.068
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.068
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.066
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.066
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.066
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.065
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.065
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.065
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.065
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.065
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.063
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.063
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.063
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.063
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.062
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.062
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.061
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.061
|
|
|
|
adenosine receptor signaling pathway
|
GO:0001973 |
7 |
0.061
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.061
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
68 |
0.061
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.060
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.060
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.060
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.060
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.060
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.059
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.059
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.059
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.059
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.059
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
17 |
0.058
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
83 |
0.058
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.058
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.057
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.057
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
5 |
0.057
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
8 |
0.057
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.057
|
|
|
|
positive regulation of dendritic spine morphogenesis
|
GO:0061003 |
3 |
0.056
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.056
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.056
|
|
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.055
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.055
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.055
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.055
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.055
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.055
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
27 |
0.054
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.054
|
Yeast |
|
|
head development
|
GO:0060322 |
247 |
0.053
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.053
|
|
|
|
t cell migration
|
GO:0072678 |
2 |
0.053
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.052
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.051
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
10 |
0.051
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.051
|
|
|
|
dna metabolic process
|
GO:0006259 |
96 |
0.051
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.050
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
43 |
0.050
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.049
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.049
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.049
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.049
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
2 |
0.049
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
19 |
0.049
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.049
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
39 |
0.048
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
2 |
0.048
|
|
|
|
protein maturation
|
GO:0051604 |
68 |
0.048
|
Mouse |
|
|
vesicle organization
|
GO:0016050 |
29 |
0.048
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.048
|
Mouse Fly |
|
|
immune system process
|
GO:0002376 |
204 |
0.048
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.047
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.047
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.047
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.046
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.046
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.046
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.046
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.046
|
|
|
|
regulation of dendritic spine morphogenesis
|
GO:0061001 |
6 |
0.046
|
|
|
|
leukocyte migration
|
GO:0050900 |
38 |
0.046
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.046
|
|
|
|
gtp catabolic process
|
GO:0006184 |
71 |
0.046
|
|
|
|
dendrite development
|
GO:0016358 |
72 |
0.046
|
|
|
|
protein processing
|
GO:0016485 |
68 |
0.046
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
61 |
0.046
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.046
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.045
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.045
|
Fly |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.045
|
Fly |
|
|
cellular protein complex assembly
|
GO:0043623 |
44 |
0.045
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.044
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
4 |
0.044
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.044
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.044
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
9 |
0.043
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.043
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.043
|
|
|
|
cell cycle process
|
GO:0022402 |
57 |
0.043
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.042
|
|
|
|
dendritic spine development
|
GO:0060996 |
20 |
0.042
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
1 |
0.042
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.042
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.042
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
37 |
0.042
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.042
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
15 |
0.041
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
194 |
0.041
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.041
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.041
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
71 |
0.041
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.041
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.040
|
|
|
|
tube morphogenesis
|
GO:0035239 |
23 |
0.040
|
Mouse |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.040
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.040
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
33 |
0.040
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.040
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.039
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.039
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.039
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
55 |
0.039
|
|
|
|
activation of phospholipase d activity
|
GO:0031584 |
2 |
0.039
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.039
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.038
|
Worm Fly |
|
|
establishment of vesicle localization
|
GO:0051650 |
31 |
0.038
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
51 |
0.038
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.038
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.037
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.037
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.037
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.037
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
4 |
0.037
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.037
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.037
|
|
|
|
protein localization to membrane
|
GO:0072657 |
36 |
0.036
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.036
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.036
|
Worm Fly |
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.036
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
56 |
0.036
|
|
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.036
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.036
|
|
|
|
vesicle transport along actin filament
|
GO:0030050 |
2 |
0.036
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.035
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.035
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.035
|
|
|
|
inflammatory response
|
GO:0006954 |
150 |
0.035
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.035
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.035
|
|
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.034
|
Fly |
|
|
leukocyte chemotaxis
|
GO:0030595 |
22 |
0.034
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.034
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.034
|
Mouse |
|
|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
1 |
0.034
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.034
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.033
|
Worm |
|
|
wound healing
|
GO:0042060 |
122 |
0.033
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.033
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
120 |
0.033
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
56 |
0.033
|
|
|
|
response to osmotic stress
|
GO:0006970 |
42 |
0.033
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.033
|
|
|
|
positive regulation of icosanoid secretion
|
GO:0032305 |
7 |
0.033
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.033
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.033
|
Fly |
|
|
cytokinetic process
|
GO:0032506 |
1 |
0.033
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.033
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
58 |
0.033
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.032
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
60 |
0.032
|
|
|
|
prostaglandin transport
|
GO:0015732 |
8 |
0.032
|
|
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
9 |
0.032
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.032
|
|
|
|
macroautophagy
|
GO:0016236 |
4 |
0.032
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.032
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
59 |
0.032
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.032
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.032
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.032
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.031
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.031
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.031
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.031
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.031
|
|
|
|
multicellular organism growth
|
GO:0035264 |
1 |
0.031
|
|
|
|
response to amine
|
GO:0014075 |
46 |
0.031
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
3 |
0.031
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.030
|
Fly |
|
|
receptor mediated endocytosis
|
GO:0006898 |
42 |
0.030
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
48 |
0.030
|
|
|
|
detection of visible light
|
GO:0009584 |
3 |
0.030
|
|
|
|
dna replication
|
GO:0006260 |
37 |
0.030
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.029
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.029
|
|
|
|
response to bacterium
|
GO:0009617 |
200 |
0.029
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.029
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.029
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.029
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.029
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.029
|
Worm Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.029
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.029
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
4 |
0.029
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
10 |
0.028
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
17 |
0.028
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.028
|
|
|
|
response to glucose
|
GO:0009749 |
136 |
0.028
|
|
|
|
lipid localization
|
GO:0010876 |
62 |
0.028
|
|
|
|
vesicle localization
|
GO:0051648 |
33 |
0.028
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.028
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.028
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.028
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
6 |
0.027
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.027
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.027
|
|
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.027
|
Fly |
|
|
tissue development
|
GO:0009888 |
252 |
0.027
|
Mouse |
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
75 |
0.027
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.027
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
33 |
0.027
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.027
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.027
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
45 |
0.026
|
|
|
|
response to amino acid
|
GO:0043200 |
75 |
0.026
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.026
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.026
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.026
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.026
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
33 |
0.026
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
16 |
0.026
|
|
|
|
gtp metabolic process
|
GO:0046039 |
72 |
0.026
|
|
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.026
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
26 |
0.026
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.025
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.025
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
52 |
0.025
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
49 |
0.025
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
2 |
0.025
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
49 |
0.025
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.025
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.025
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.024
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
111 |
0.024
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
36 |
0.024
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.024
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.024
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.024
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
59 |
0.024
|
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.024
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.024
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.024
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
51 |
0.024
|
|
|
|
organelle localization
|
GO:0051640 |
55 |
0.024
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
57 |
0.024
|
|
|
|
growth
|
GO:0040007 |
165 |
0.023
|
Yeast |
|
|
positive regulation of t cell migration
|
GO:2000406 |
1 |
0.023
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.023
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.023
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
8 |
0.023
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.023
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
4 |
0.023
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.023
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.023
|
|
|
|
hemopoiesis
|
GO:0030097 |
34 |
0.022
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.022
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
50 |
0.022
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.022
|
Mouse |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.022
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.022
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.022
|
|
|
|
sterol transport
|
GO:0015918 |
6 |
0.022
|
|
|
|
regulation of organic acid transport
|
GO:0032890 |
35 |
0.022
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.022
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.021
|
|
|
|
jak stat cascade
|
GO:0007259 |
26 |
0.021
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.021
|
|
|
|
g protein coupled purinergic receptor signaling pathway
|
GO:0035588 |
8 |
0.021
|
|
|
|
immune system development
|
GO:0002520 |
41 |
0.021
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.021
|
Fly |
|
|
fatty acid metabolic process
|
GO:0006631 |
99 |
0.021
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.021
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.021
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.021
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
3 |
0.020
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.020
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.020
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.020
|
|
|
|
endomembrane system organization
|
GO:0010256 |
48 |
0.020
|
|
|
|
response to cadmium ion
|
GO:0046686 |
35 |
0.020
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.020
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.020
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.020
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.020
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.019
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
1 |
0.019
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.019
|
|
|
|
positive regulation of cell migration involved in sprouting angiogenesis
|
GO:0090050 |
2 |
0.019
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.019
|
Worm Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.019
|
|
|
|
icosanoid biosynthetic process
|
GO:0046456 |
18 |
0.019
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
30 |
0.019
|
|
|
|
startle response
|
GO:0001964 |
2 |
0.019
|
|
|
|
cellular response to heat
|
GO:0034605 |
9 |
0.018
|
|
|
|
ovulation cycle process
|
GO:0022602 |
50 |
0.018
|
|
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
6 |
0.018
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
94 |
0.018
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
103 |
0.018
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
1 |
0.018
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.018
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.018
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.018
|
Fly |
|
|
cell cycle checkpoint
|
GO:0000075 |
2 |
0.018
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
42 |
0.018
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
41 |
0.018
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
43 |
0.018
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.018
|
Fly |
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
4 |
0.018
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.018
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.018
|
|
|
|
membrane fusion
|
GO:0061025 |
26 |
0.017
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.017
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
3 |
0.017
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
65 |
0.017
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.017
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
56 |
0.017
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.017
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.017
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.017
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.017
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.017
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
42 |
0.017
|
|
|
|
regulation of dendritic spine development
|
GO:0060998 |
16 |
0.017
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
55 |
0.017
|
|
|
|
protein polymerization
|
GO:0051258 |
22 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.017
|
|
|
|
acid secretion
|
GO:0046717 |
48 |
0.016
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
15 |
0.016
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.016
|
Yeast |
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.016
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
31 |
0.016
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
1 |
0.016
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
48 |
0.016
|
|
|
|
secondary metabolic process
|
GO:0019748 |
15 |
0.016
|
|
|
|
exocytosis
|
GO:0006887 |
60 |
0.016
|
|
|
|
locomotory behavior
|
GO:0007626 |
15 |
0.016
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
52 |
0.016
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.016
|
Mouse Fly |
|
|
organelle assembly
|
GO:0070925 |
22 |
0.016
|
|
|
|
acrosome assembly
|
GO:0001675 |
3 |
0.016
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.016
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.016
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
44 |
0.016
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
65 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
3 |
0.016
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
12 |
0.016
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
22 |
0.016
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
38 |
0.016
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.016
|
Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.016
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.016
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
24 |
0.016
|
|
|
|
g protein coupled glutamate receptor signaling pathway
|
GO:0007216 |
8 |
0.016
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.016
|
|
|
|
gonad development
|
GO:0008406 |
104 |
0.016
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.016
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.015
|
|
