Rattus norvegicus

68 known processes

Prkar1a

protein kinase, cAMP-dependent, regulatory, type I, alpha

(Aliases: RIIA)

Prkar1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component biogenesis GO:0044085 368 0.585
regulation of organelle organization GO:0033043 80 0.294
regulation of cellular component organization GO:0051128 368 0.289
cellular catabolic process GO:0044248 295 0.247
regulation of molecular function GO:0065009 398 0.235
anatomical structure morphogenesis GO:0009653 298 0.224
organic substance catabolic process GO:1901575 316 0.190
regulation of protein modification process GO:0031399 194 0.187
protein complex assembly GO:0006461 263 0.141
regulation of protein metabolic process GO:0051246 289 0.140
macromolecule localization GO:0033036 252 0.137
cellular component assembly GO:0022607 360 0.135
spindle organization GO:0007051 2 0.134
programmed cell death GO:0012501 392 0.133
intracellular signal transduction GO:0035556 314 0.132
vesicle mediated transport GO:0016192 181 0.131
catabolic process GO:0009056 351 0.129
tissue development GO:0009888 252 0.127
macromolecular complex assembly GO:0065003 273 0.114
multi organism reproductive process GO:0044703 262 0.114
positive regulation of cell communication GO:0010647 271 0.113
organelle organization GO:0006996 266 0.111
regulation of actin nucleation GO:0051125 2 0.108
regulation of programmed cell death GO:0043067 341 0.106
cell cycle GO:0007049 101 0.103
protein oligomerization GO:0051259 191 0.102
protein complex subunit organization GO:0071822 302 0.102
regulation of phosphate metabolic process GO:0019220 349 0.102
protein complex biogenesis GO:0070271 263 0.099
protein modification by small protein conjugation or removal GO:0070647 35 0.094
ras protein signal transduction GO:0007265 29 0.093
single organism catabolic process GO:0044712 283 0.092
endocytosis GO:0006897 84 0.089
positive regulation of signaling GO:0023056 270 0.088
behavior GO:0007610 205 0.088
regulation of phosphorylation GO:0042325 248 0.082
regulation of apoptotic process GO:0042981 335 0.081
regulation of synaptic transmission GO:0050804 141 0.081
oxoacid metabolic process GO:0043436 290 0.080
enzyme linked receptor protein signaling pathway GO:0007167 116 0.080
cellular nitrogen compound catabolic process GO:0044270 163 0.079
apoptotic process GO:0006915 381 0.079
intracellular transport GO:0046907 185 0.078
positive regulation of protein modification process GO:0031401 142 0.075
regulation of neuron differentiation GO:0045664 208 0.075
establishment of protein localization GO:0045184 141 0.073
response to insulin GO:0032868 133 0.072
nucleobase containing compound catabolic process GO:0034655 152 0.071
homeostatic process GO:0042592 331 0.071
aromatic compound catabolic process GO:0019439 168 0.070
cellular homeostasis GO:0019725 252 0.070
transmembrane transport GO:0055085 412 0.068
regulation of cell differentiation GO:0045595 320 0.066
cellular macromolecule localization GO:0070727 122 0.065
growth GO:0040007 165 0.064
chromosome segregation GO:0007059 2 0.064
organonitrogen compound catabolic process GO:1901565 179 0.064
developmental process involved in reproduction GO:0003006 159 0.064
membrane organization GO:0061024 94 0.064
regulation of cellular protein metabolic process GO:0032268 267 0.063
ion transmembrane transport GO:0034220 365 0.063
regulation of multicellular organismal development GO:2000026 376 0.062
negative regulation of developmental process GO:0051093 125 0.061
regulation of neuron projection development GO:0010975 161 0.059
single organism organelle organization GO:1902589 180 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.056
arp2 3 complex mediated actin nucleation GO:0034314 2 0.056
cellular amino acid metabolic process GO:0006520 107 0.054
negative regulation of phosphorus metabolic process GO:0010563 80 0.054
sexual reproduction GO:0019953 148 0.054
positive regulation of nucleic acid templated transcription GO:1903508 197 0.054
cellular metal ion homeostasis GO:0006875 172 0.053
brain development GO:0007420 247 0.053
cation homeostasis GO:0055080 195 0.053
cellular cation homeostasis GO:0030003 180 0.051
cell projection organization GO:0030030 302 0.051
response to peptide GO:1901652 292 0.051
reproductive process GO:0022414 372 0.051
regulation of hydrolase activity GO:0051336 143 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.050
cytoskeleton organization GO:0007010 111 0.050
positive regulation of signal transduction GO:0009967 175 0.049
negative regulation of multicellular organismal process GO:0051241 203 0.049
single organism reproductive process GO:0044702 297 0.049
maintenance of location GO:0051235 17 0.048
regulation of system process GO:0044057 208 0.048
arf protein signal transduction GO:0032011 0 0.047
positive regulation of phosphorylation GO:0042327 177 0.047
negative regulation of apoptotic process GO:0043066 181 0.046
response to axon injury GO:0048678 59 0.046
positive regulation of molecular function GO:0044093 230 0.046
protein phosphorylation GO:0006468 345 0.046
head development GO:0060322 247 0.045
response to metal ion GO:0010038 253 0.045
single organism behavior GO:0044708 130 0.044
cellular chemical homeostasis GO:0055082 247 0.043
cellular response to cytokine stimulus GO:0071345 127 0.043
regulation of signal transduction GO:0009966 318 0.042
regulation of anatomical structure size GO:0090066 135 0.042
neuron development GO:0048666 286 0.042
rna metabolic process GO:0016070 406 0.042
macromolecular complex subunit organization GO:0043933 339 0.041
positive regulation of protein metabolic process GO:0051247 178 0.041
negative regulation of programmed cell death GO:0043069 183 0.041
secretion GO:0046903 307 0.040
cellular amine metabolic process GO:0044106 38 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
nucleoside monophosphate catabolic process GO:0009125 56 0.039
protein transport GO:0015031 132 0.038
organic cyclic compound catabolic process GO:1901361 175 0.038
ion homeostasis GO:0050801 212 0.038
nitrogen compound transport GO:0071705 229 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
dendrite development GO:0016358 72 0.037
single organism intracellular transport GO:1902582 166 0.037
cellular response to external stimulus GO:0071496 118 0.037
negative regulation of signaling GO:0023057 157 0.037
regulation of secretion GO:0051046 224 0.037
synaptic transmission GO:0007268 235 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
regulation of rna metabolic process GO:0051252 391 0.037
negative regulation of cell differentiation GO:0045596 99 0.037
regulation of cell development GO:0060284 263 0.036
epithelium development GO:0060429 96 0.036
aging GO:0007568 241 0.035
cellular response to hormone stimulus GO:0032870 247 0.035
organic hydroxy compound metabolic process GO:1901615 115 0.035
negative regulation of response to stimulus GO:0048585 155 0.035
cellular ion homeostasis GO:0006873 184 0.034
cation transport GO:0006812 382 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
purine nucleoside monophosphate catabolic process GO:0009128 55 0.034
negative regulation of cell communication GO:0010648 158 0.034
negative regulation of molecular function GO:0044092 133 0.033
cytoplasmic transport GO:0016482 115 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
positive regulation of gene expression GO:0010628 244 0.032
chemical homeostasis GO:0048878 292 0.032
cell projection morphogenesis GO:0048858 123 0.032
ribonucleoside metabolic process GO:0009119 174 0.032
lipid storage GO:0019915 1 0.032
neuron differentiation GO:0030182 368 0.032
protein modification by small protein conjugation GO:0032446 31 0.032
regulation of nervous system development GO:0051960 264 0.031
small gtpase mediated signal transduction GO:0007264 36 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
inorganic ion transmembrane transport GO:0098660 229 0.031
regulation of calcium ion transmembrane transport GO:1903169 18 0.030
rna biosynthetic process GO:0032774 380 0.030
cation transmembrane transport GO:0098655 263 0.030
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.030
metal ion transport GO:0030001 289 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
positive regulation of actin filament polymerization GO:0030838 5 0.030
learning or memory GO:0007611 90 0.030
negative regulation of nervous system development GO:0051961 79 0.029
regulation of stem cell differentiation GO:2000736 2 0.029
peptidyl tyrosine phosphorylation GO:0018108 72 0.029
negative regulation of cell development GO:0010721 82 0.029
negative regulation of cellular component organization GO:0051129 83 0.028
circulatory system development GO:0072359 134 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
p38mapk cascade GO:0038066 1 0.028
regulation of protein phosphorylation GO:0001932 183 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
response to inorganic substance GO:0010035 377 0.027
regulation of growth GO:0040008 105 0.026
cell morphogenesis GO:0000902 142 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
response to nutrient levels GO:0031667 370 0.026
response to peptide hormone GO:0043434 278 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
microtubule based process GO:0007017 36 0.025
protein localization GO:0008104 191 0.025
regulation of metal ion transport GO:0010959 118 0.025
regulation of neurogenesis GO:0050767 247 0.025
purine nucleotide catabolic process GO:0006195 136 0.025
multicellular organism reproduction GO:0032504 233 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of smoothened signaling pathway GO:0008589 2 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.024
response to biotic stimulus GO:0009607 226 0.024
divalent metal ion transport GO:0070838 132 0.024
cognition GO:0050890 92 0.024
calcium ion transmembrane transport GO:0070588 70 0.024
protein dephosphorylation GO:0006470 38 0.024
regulation of protein localization GO:0032880 81 0.024
neurological system process GO:0050877 219 0.024
regulation of cell projection organization GO:0031344 175 0.024
cardiac ventricle development GO:0003231 1 0.023
regulation of proteasomal protein catabolic process GO:0061136 4 0.023
regulation of ubiquitin protein transferase activity GO:0051438 1 0.023
carbohydrate derivative catabolic process GO:1901136 147 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
regulation of cellular catabolic process GO:0031329 101 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
regulation of cellular localization GO:0060341 263 0.022
carbohydrate metabolic process GO:0005975 130 0.022
negative regulation of phosphate metabolic process GO:0045936 80 0.022
organic acid metabolic process GO:0006082 292 0.022
developmental growth GO:0048589 100 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.022
organophosphate catabolic process GO:0046434 148 0.022
macroautophagy GO:0016236 4 0.022
positive regulation of protein binding GO:0032092 9 0.022
carboxylic acid catabolic process GO:0046395 49 0.022
negative regulation of protein modification process GO:0031400 52 0.021
regulation of protein complex assembly GO:0043254 33 0.021
protein k6 linked ubiquitination GO:0085020 1 0.021
nucleoside metabolic process GO:0009116 179 0.021
mitotic spindle organization GO:0007052 2 0.021
tube development GO:0035295 89 0.021
regulation of heart contraction GO:0008016 48 0.021
muscle system process GO:0003012 115 0.020
negative regulation of metabolic process GO:0009892 331 0.020
proteolysis GO:0006508 175 0.020
rna localization GO:0006403 4 0.020
response to other organism GO:0051707 220 0.020
sensory organ development GO:0007423 74 0.020
muscle structure development GO:0061061 87 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
meiotic cell cycle process GO:1903046 3 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.020
peptidyl amino acid modification GO:0018193 126 0.020
protein ubiquitination GO:0016567 28 0.020
regulation of dendrite development GO:0050773 59 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
calcium ion transport GO:0006816 131 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
purine containing compound metabolic process GO:0072521 253 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
purine ribonucleoside catabolic process GO:0046130 124 0.019
response to radiation GO:0009314 137 0.019
regulation of transcription dna templated GO:0006355 374 0.019
positive regulation of secretion GO:0051047 140 0.019
negative regulation of cell death GO:0060548 229 0.019
golgi vesicle transport GO:0048193 22 0.019
heterocycle catabolic process GO:0046700 167 0.018
cell cell signaling GO:0007267 335 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
response to wounding GO:0009611 254 0.018
regulation of catalytic activity GO:0050790 304 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
cellular component morphogenesis GO:0032989 155 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of cell cycle g2 m phase transition GO:1902749 4 0.018
semicircular canal development GO:0060872 1 0.018
cellular response to stress GO:0033554 269 0.018
lipid localization GO:0010876 62 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
regulation of cell morphogenesis GO:0022604 77 0.017
immune system process GO:0002376 204 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
regulation of muscle system process GO:0090257 79 0.017
establishment of chromosome localization GO:0051303 1 0.017
cell type specific apoptotic process GO:0097285 134 0.017
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.017
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
adult behavior GO:0030534 16 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
cellular protein complex assembly GO:0043623 44 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
heart development GO:0007507 72 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
positive regulation of protein dephosphorylation GO:0035307 4 0.016
organophosphate metabolic process GO:0019637 370 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
nucleoside catabolic process GO:0009164 126 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
organic anion transport GO:0015711 132 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
intracellular protein transport GO:0006886 79 0.016
amine metabolic process GO:0009308 38 0.016
regulation of ion transport GO:0043269 245 0.016
locomotion GO:0040011 237 0.016
adult locomotory behavior GO:0008344 4 0.016
protein localization to organelle GO:0033365 57 0.016
reproduction GO:0000003 245 0.015
cardiovascular system development GO:0072358 134 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
olfactory behavior GO:0042048 2 0.015
central nervous system development GO:0007417 311 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
circadian regulation of gene expression GO:0032922 3 0.015
epidermal growth factor receptor signaling pathway GO:0007173 23 0.015
hormone secretion GO:0046879 115 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
heart morphogenesis GO:0003007 3 0.015
transcription dna templated GO:0006351 377 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
cell growth GO:0016049 104 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
nucleic acid templated transcription GO:0097659 379 0.015
metal ion homeostasis GO:0055065 186 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
reproductive system development GO:0061458 128 0.014
regulation of hormone levels GO:0010817 187 0.014
regulation of developmental growth GO:0048638 45 0.014
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of protein phosphorylation GO:0001933 44 0.014
cellular protein localization GO:0034613 122 0.014
anion transport GO:0006820 178 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
mapk cascade GO:0000165 140 0.014
organ morphogenesis GO:0009887 75 0.014
muscle organ development GO:0007517 50 0.013
positive regulation of catabolic process GO:0009896 78 0.013
actin filament organization GO:0007015 42 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
cellular macromolecule catabolic process GO:0044265 29 0.013
neuromuscular process GO:0050905 2 0.013
regulation of protein kinase activity GO:0045859 105 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
single organism biosynthetic process GO:0044711 342 0.013
membrane fusion GO:0061025 26 0.013
nucleotide catabolic process GO:0009166 139 0.013
reproductive structure development GO:0048608 128 0.013
chemosensory behavior GO:0007635 2 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of calcium ion transport GO:0051924 77 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
mitotic cell cycle phase transition GO:0044772 20 0.013
dephosphorylation GO:0016311 98 0.013
regulation of response to external stimulus GO:0032101 106 0.013
erbb signaling pathway GO:0038127 23 0.012
response to oxidative stress GO:0006979 186 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
regulation of ion homeostasis GO:2000021 63 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
secretion by cell GO:0032940 248 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
organelle assembly GO:0070925 22 0.012
organelle fusion GO:0048284 17 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
cell part morphogenesis GO:0032990 123 0.012
regulation of lipid storage GO:0010883 1 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
positive regulation of transport GO:0051050 245 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
cellular response to oxygen containing compound GO:1901701 386 0.011
organic hydroxy compound transport GO:0015850 77 0.011
ear development GO:0043583 21 0.011
circadian rhythm GO:0007623 88 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of secretion by cell GO:1903530 208 0.011
regulation of transferase activity GO:0051338 123 0.011
regulation of cell proliferation GO:0042127 359 0.011
response to external biotic stimulus GO:0043207 221 0.011
response to activity GO:0014823 73 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
regulation of intracellular transport GO:0032386 65 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 13 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
regulation of body fluid levels GO:0050878 90 0.011
ubiquitin dependent protein catabolic process GO:0006511 14 0.011
axon development GO:0061564 96 0.011
regulation of membrane potential GO:0042391 110 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
protein k63 linked ubiquitination GO:0070534 2 0.011
receptor metabolic process GO:0043112 18 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
response to decreased oxygen levels GO:0036293 237 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
neuron projection development GO:0031175 273 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
multicellular organismal signaling GO:0035637 44 0.010
positive regulation of cell death GO:0010942 184 0.010
regulation of blood circulation GO:1903522 110 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
embryonic pattern specification GO:0009880 1 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
response to glucocorticoid GO:0051384 223 0.010

Prkar1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037