Rattus norvegicus

46 known processes

Prkar2b

protein kinase, cAMP dependent regulatory, type II beta

(Aliases: MGC116401,RATDNA)

Prkar2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.132
organonitrogen compound biosynthetic process GO:1901566 167 0.104
organic acid metabolic process GO:0006082 292 0.102
Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.097
organophosphate metabolic process GO:0019637 370 0.097
nucleoside phosphate metabolic process GO:0006753 283 0.091
ribonucleotide biosynthetic process GO:0009260 85 0.089
carbohydrate derivative biosynthetic process GO:1901137 124 0.077
carbohydrate derivative metabolic process GO:1901135 346 0.074
nucleotide metabolic process GO:0009117 279 0.070
cellular component biogenesis GO:0044085 368 0.068
Rat
carboxylic acid metabolic process GO:0019752 289 0.061
Mouse
cellular amino acid metabolic process GO:0006520 107 0.058
negative regulation of cellular metabolic process GO:0031324 281 0.057
Human
organophosphate biosynthetic process GO:0090407 143 0.056
cellular component assembly GO:0022607 360 0.056
Rat
purine containing compound metabolic process GO:0072521 253 0.056
single organism catabolic process GO:0044712 283 0.054
ribose phosphate biosynthetic process GO:0046390 87 0.052
cation transport GO:0006812 382 0.052
ribonucleotide metabolic process GO:0009259 231 0.048
purine nucleotide biosynthetic process GO:0006164 83 0.047
response to inorganic substance GO:0010035 377 0.046
oxoacid metabolic process GO:0043436 290 0.046
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.045
nucleotide biosynthetic process GO:0009165 98 0.041
ribose phosphate metabolic process GO:0019693 235 0.041
protein phosphorylation GO:0006468 345 0.040
single organism carbohydrate metabolic process GO:0044723 118 0.040
nucleoside phosphate biosynthetic process GO:1901293 102 0.040
response to extracellular stimulus GO:0009991 380 0.039
purine ribonucleotide metabolic process GO:0009150 227 0.039
response to peptide hormone GO:0043434 278 0.039
regulation of phosphorylation GO:0042325 248 0.038
protein complex biogenesis GO:0070271 263 0.038
Rat
macromolecular complex subunit organization GO:0043933 339 0.038
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.037
regulation of cell proliferation GO:0042127 359 0.036
response to estrogen GO:0043627 232 0.035
secretion by cell GO:0032940 248 0.035
response to peptide GO:1901652 292 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
cellular response to endogenous stimulus GO:0071495 377 0.034
response to nutrient levels GO:0031667 370 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.032
purine nucleotide metabolic process GO:0006163 229 0.032
negative regulation of metabolic process GO:0009892 331 0.032
Human
central nervous system development GO:0007417 311 0.032
catabolic process GO:0009056 351 0.032
response to decreased oxygen levels GO:0036293 237 0.032
programmed cell death GO:0012501 392 0.031
positive regulation of developmental process GO:0051094 283 0.031
rna metabolic process GO:0016070 406 0.031
purine containing compound biosynthetic process GO:0072522 85 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
regulation of apoptotic process GO:0042981 335 0.030
secretion GO:0046903 307 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.030
response to hypoxia GO:0001666 231 0.030
protein complex subunit organization GO:0071822 302 0.030
Rat
cellular response to organonitrogen compound GO:0071417 197 0.029
regulation of programmed cell death GO:0043067 341 0.029
cyclic nucleotide metabolic process GO:0009187 80 0.029
behavior GO:0007610 205 0.029
Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.029
regulation of ion transport GO:0043269 245 0.029
apoptotic process GO:0006915 381 0.029
circulatory system process GO:0003013 183 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
Human
cellular lipid metabolic process GO:0044255 208 0.028
Mouse
response to wounding GO:0009611 254 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
macromolecular complex assembly GO:0065003 273 0.028
Rat
response to external biotic stimulus GO:0043207 221 0.027
cellular amine metabolic process GO:0044106 38 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
homeostatic process GO:0042592 331 0.027
response to acid chemical GO:0001101 222 0.027
oxidation reduction process GO:0055114 304 0.026
cellular catabolic process GO:0044248 295 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
transcription dna templated GO:0006351 377 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
response to corticosteroid GO:0031960 235 0.025
positive regulation of cell death GO:0010942 184 0.025
intracellular signal transduction GO:0035556 314 0.025
regulation of cellular localization GO:0060341 263 0.024
small molecule biosynthetic process GO:0044283 124 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
cyclic purine nucleotide metabolic process GO:0052652 62 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
aging GO:0007568 241 0.024
amine metabolic process GO:0009308 38 0.024
regulation of catabolic process GO:0009894 113 0.024
cellular response to nitrogen compound GO:1901699 210 0.023
response to oxygen levels GO:0070482 265 0.023
muscle system process GO:0003012 115 0.023
response to toxic substance GO:0009636 133 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
organic acid transport GO:0015849 116 0.023
organic substance catabolic process GO:1901575 316 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
regulation of rna metabolic process GO:0051252 391 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
cell projection organization GO:0030030 302 0.022
Fly
nucleoside metabolic process GO:0009116 179 0.022
response to nutrient GO:0007584 248 0.022
negative regulation of cell death GO:0060548 229 0.022
cellular response to peptide hormone stimulus GO:0071375 120 0.022
regulation of secretion GO:0051046 224 0.022
central nervous system neuron axonogenesis GO:0021955 1 0.022
organelle organization GO:0006996 266 0.022
response to carbohydrate GO:0009743 183 0.021
regulation of cell differentiation GO:0045595 320 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
regulation of molecular function GO:0065009 398 0.021
regulation of neuron apoptotic process GO:0043523 83 0.021
protein complex assembly GO:0006461 263 0.021
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
response to monosaccharide GO:0034284 159 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
cellular response to peptide GO:1901653 133 0.020
anion transport GO:0006820 178 0.020
metal ion transport GO:0030001 289 0.020
generation of precursor metabolites and energy GO:0006091 62 0.020
chemical homeostasis GO:0048878 292 0.020
negative regulation of phosphate metabolic process GO:0045936 80 0.020
Human
cell morphogenesis GO:0000902 142 0.020
Fly
regulation of hormone levels GO:0010817 187 0.020
response to glucocorticoid GO:0051384 223 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
response to biotic stimulus GO:0009607 226 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
negative regulation of cell communication GO:0010648 158 0.019
protein oligomerization GO:0051259 191 0.019
Rat
response to radiation GO:0009314 137 0.019
regulation of nervous system development GO:0051960 264 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
learning or memory GO:0007611 90 0.019
Mouse
cellular component movement GO:0006928 248 0.019
Fly
cyclic nucleotide biosynthetic process GO:0009190 63 0.019
cell cell signaling GO:0007267 335 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
negative regulation of molecular function GO:0044092 133 0.019
Human
response to oxidative stress GO:0006979 186 0.019
nucleic acid templated transcription GO:0097659 379 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
negative regulation of gene expression GO:0010629 199 0.019
regeneration GO:0031099 163 0.018
cell type specific apoptotic process GO:0097285 134 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
cellular response to insulin stimulus GO:0032869 81 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
lipid biosynthetic process GO:0008610 128 0.018
proteolysis GO:0006508 175 0.018
cellular carbohydrate metabolic process GO:0044262 72 0.018
neuron death GO:0070997 127 0.018
response to metal ion GO:0010038 253 0.018
cgmp biosynthetic process GO:0006182 15 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
response to hexose GO:0009746 144 0.018
cell part morphogenesis GO:0032990 123 0.017
Fly
peptidyl amino acid modification GO:0018193 126 0.017
cellular ketone metabolic process GO:0042180 51 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
organic hydroxy compound transport GO:0015850 77 0.017
defense response GO:0006952 194 0.017
regulation of secretion by cell GO:1903530 208 0.017
multi organism reproductive process GO:0044703 262 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
signal release GO:0023061 145 0.017
rna biosynthetic process GO:0032774 380 0.017
cellular ion homeostasis GO:0006873 184 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.017
regulation of amine transport GO:0051952 54 0.017
organic anion transport GO:0015711 132 0.016
cognition GO:0050890 92 0.016
Mouse
reproductive process GO:0022414 372 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
Fly
reproduction GO:0000003 245 0.016
positive regulation of cellular component biogenesis GO:0044089 55 0.016
response to ethanol GO:0045471 162 0.016
Fly
locomotion GO:0040011 237 0.016
Fly
regulation of protein kinase activity GO:0045859 105 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
regulation of protein modification process GO:0031399 194 0.016
lipid metabolic process GO:0006629 283 0.016
Mouse
reactive nitrogen species metabolic process GO:2001057 1 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of protein metabolic process GO:0051246 289 0.016
response to insulin GO:0032868 133 0.016
response to herbicide GO:0009635 16 0.016
regulation of mapk cascade GO:0043408 116 0.016
regulation of system process GO:0044057 208 0.016
cell motility GO:0048870 202 0.016
ion transmembrane transport GO:0034220 365 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
sulfur compound metabolic process GO:0006790 70 0.016
immune system process GO:0002376 204 0.016
reactive oxygen species metabolic process GO:0072593 37 0.015
neuron projection development GO:0031175 273 0.015
Fly
carbohydrate metabolic process GO:0005975 130 0.015
neurological system process GO:0050877 219 0.015
Mouse
positive regulation of apoptotic process GO:0043065 154 0.015
negative regulation of neuron death GO:1901215 69 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
response to glucose GO:0009749 136 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
single organism behavior GO:0044708 130 0.015
Mouse Fly
regulation of anatomical structure size GO:0090066 135 0.015
regulation of membrane potential GO:0042391 110 0.015
transmembrane transport GO:0055085 412 0.015
positive regulation of signaling GO:0023056 270 0.015
positive regulation of molecular function GO:0044093 230 0.015
cellular homeostasis GO:0019725 252 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
cell growth GO:0016049 104 0.015
maintenance of location GO:0051235 17 0.015
regulation of hydrolase activity GO:0051336 143 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of secretion GO:0051047 140 0.015
inflammatory response GO:0006954 150 0.015
response to organophosphorus GO:0046683 102 0.015
neuron projection morphogenesis GO:0048812 122 0.014
Fly
taxis GO:0042330 67 0.014
Fly
response to hydrogen peroxide GO:0042542 89 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
amino acid transport GO:0006865 70 0.014
response to reactive oxygen species GO:0000302 120 0.014
regulation of catalytic activity GO:0050790 304 0.014
regulation of blood pressure GO:0008217 83 0.014
adult locomotory behavior GO:0008344 4 0.014
positive regulation of gene expression GO:0010628 244 0.014
regulation of cell projection organization GO:0031344 175 0.014
sexual reproduction GO:0019953 148 0.014
negative regulation of protein phosphorylation GO:0001933 44 0.014
Human
positive regulation of cell development GO:0010720 176 0.014
response to other organism GO:0051707 220 0.014
organ regeneration GO:0031100 101 0.014
regulation of organelle organization GO:0033043 80 0.014
nucleoside monophosphate biosynthetic process GO:0009124 28 0.014
growth GO:0040007 165 0.014
regulation of catecholamine secretion GO:0050433 32 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
positive regulation of cell communication GO:0010647 271 0.014
regulation of neuron death GO:1901214 115 0.013
chromatin assembly or disassembly GO:0006333 1 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
ras protein signal transduction GO:0007265 29 0.013
response to cytokine GO:0034097 215 0.013
response to estradiol GO:0032355 164 0.013
response to ketone GO:1901654 182 0.013
cellular cation homeostasis GO:0030003 180 0.013
regulation of cell development GO:0060284 263 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
Human
rhythmic process GO:0048511 156 0.013
Fly
synaptic transmission GO:0007268 235 0.013
positive regulation of transport GO:0051050 245 0.013
developmental growth GO:0048589 100 0.013
vascular process in circulatory system GO:0003018 96 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
chemosensory behavior GO:0007635 2 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
brain development GO:0007420 247 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
cation homeostasis GO:0055080 195 0.013
positive regulation of nervous system development GO:0051962 178 0.013
mapk cascade GO:0000165 140 0.013
olfactory learning GO:0008355 1 0.013
cofactor metabolic process GO:0051186 95 0.013
dephosphorylation GO:0016311 98 0.013
nucleobase biosynthetic process GO:0046112 2 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
positive regulation of synaptic transmission GO:0050806 62 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
Human
regulation of locomotion GO:0040012 148 0.013
tissue development GO:0009888 252 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
male mating behavior GO:0060179 3 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
response to vitamin GO:0033273 131 0.012
regulation of cellular component movement GO:0051270 150 0.012
cellular response to stress GO:0033554 269 0.012
regulation of response to stress GO:0080134 126 0.012
bmp signaling pathway GO:0030509 4 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
olfactory behavior GO:0042048 2 0.012
amide transport GO:0042886 105 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
localization of cell GO:0051674 202 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
camp metabolic process GO:0046058 63 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
blood circulation GO:0008015 183 0.012
negative regulation of developmental process GO:0051093 125 0.012
cation transmembrane transport GO:0098655 263 0.012
chromosome segregation GO:0007059 2 0.012
negative regulation of signaling GO:0023057 157 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
regulation of transcription dna templated GO:0006355 374 0.012
response to temperature stimulus GO:0009266 94 0.012
monoamine transport GO:0015844 43 0.012
positive regulation of ion transport GO:0043270 94 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
regulation of growth GO:0040008 105 0.012
cell adhesion GO:0007155 110 0.012
single organism reproductive process GO:0044702 297 0.011
cell cycle checkpoint GO:0000075 2 0.011
neuron differentiation GO:0030182 368 0.011
Fly
reactive oxygen species biosynthetic process GO:1903409 8 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
Fly
protein homooligomerization GO:0051260 91 0.011
memory GO:0007613 54 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
phospholipid metabolic process GO:0006644 61 0.011
response to fatty acid GO:0070542 65 0.011
nitrogen compound transport GO:0071705 229 0.011
coenzyme metabolic process GO:0006732 86 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
peptide transport GO:0015833 97 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
gland development GO:0048732 155 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
ribonucleoside biosynthetic process GO:0042455 25 0.011
regulation of metal ion transport GO:0010959 118 0.011
response to bacterium GO:0009617 200 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
ion homeostasis GO:0050801 212 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of muscle system process GO:0090257 79 0.010
regulation of cell adhesion GO:0030155 52 0.010
purine containing compound catabolic process GO:0072523 138 0.010
cell migration GO:0016477 197 0.010
response to camp GO:0051591 91 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
regulation of cellular component organization GO:0051128 368 0.010
nucleotide catabolic process GO:0009166 139 0.010
cellular response to lipid GO:0071396 201 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
negative regulation of ion transport GO:0043271 51 0.010
glucose homeostasis GO:0042593 75 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
positive regulation of odontogenesis of dentin containing tooth GO:0042488 1 0.010
positive regulation of transcription factor import into nucleus GO:0042993 4 0.010
neuron development GO:0048666 286 0.010
Fly
negative regulation of neuron apoptotic process GO:0043524 45 0.010
neuronal action potential GO:0019228 35 0.010
biological adhesion GO:0022610 110 0.010
calcium ion transport GO:0006816 131 0.010
regulation of response to external stimulus GO:0032101 106 0.010
detection of visible light GO:0009584 3 0.010
gonad development GO:0008406 104 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010

Prkar2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.041
neuropathy DOID:870 0 0.015
cardiovascular system disease DOID:1287 0 0.012
vascular disease DOID:178 0 0.012
artery disease DOID:0050828 0 0.012
urinary system disease DOID:18 0 0.010