|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.571
|
Human |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.492
|
|
|
|
vasculogenesis
|
GO:0001570 |
3 |
0.489
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.486
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.480
|
Human |
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.450
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.385
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.377
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.372
|
Human |
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.365
|
Human |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.341
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.323
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.316
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.313
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.312
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.304
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.295
|
Human Fly |
|
|
cell motility
|
GO:0048870 |
202 |
0.286
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.285
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.280
|
Worm |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
10 |
0.269
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.261
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.259
|
|
|
|
biological adhesion
|
GO:0022610 |
110 |
0.253
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.252
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.251
|
Human Rat |
|
|
programmed cell death
|
GO:0012501 |
392 |
0.251
|
Human Rat |
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.243
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.231
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.228
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.226
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.220
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.219
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.218
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.216
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.214
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.213
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.205
|
Worm |
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.194
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.193
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.192
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.192
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.190
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.185
|
Human |
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.185
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.183
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.181
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.181
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.180
|
Worm |
|
|
cellular component movement
|
GO:0006928 |
248 |
0.178
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.177
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.176
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
97 |
0.175
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.175
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.171
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.170
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.168
|
Fly |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.166
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.164
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.162
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.162
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.161
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.157
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.156
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.154
|
Worm |
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.152
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
65 |
0.151
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.146
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.145
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.144
|
Human Mouse |
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.143
|
|
|
|
chemotaxis
|
GO:0006935 |
66 |
0.142
|
Worm |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.141
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.140
|
Human Mouse |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.139
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.139
|
Fly |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.136
|
Human |
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.134
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.133
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.131
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.131
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.131
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.130
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.129
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.127
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.126
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.125
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.125
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.124
|
|
|
|
head development
|
GO:0060322 |
247 |
0.124
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.122
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
169 |
0.122
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.122
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.121
|
Human |
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.119
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.117
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.116
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.115
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.115
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
102 |
0.114
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.114
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.113
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.113
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.113
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.113
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.112
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.111
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
16 |
0.111
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.111
|
Fly |
|
|
organelle organization
|
GO:0006996 |
266 |
0.110
|
Fly |
|
|
neurological system process
|
GO:0050877 |
219 |
0.108
|
Worm Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.108
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.108
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.107
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.107
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
36 |
0.107
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.107
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.106
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
147 |
0.101
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
120 |
0.100
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.100
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.099
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.099
|
Human Rat |
|
|
blood vessel development
|
GO:0001568 |
69 |
0.099
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.098
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
65 |
0.098
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.096
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.096
|
Human Rat |
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.095
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.095
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.094
|
Human |
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
4 |
0.094
|
|
|
|
gtp catabolic process
|
GO:0006184 |
71 |
0.094
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.094
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.093
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.092
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
174 |
0.092
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
44 |
0.091
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.091
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.091
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.089
|
Rat |
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.089
|
Fly |
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.089
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.088
|
Worm |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.087
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.087
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.085
|
Rat |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.084
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.084
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.083
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.083
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.082
|
Worm |
|
|
cell migration
|
GO:0016477 |
197 |
0.081
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.081
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.080
|
Worm |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.079
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.079
|
Rat |
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.079
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.079
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.078
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
46 |
0.078
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.078
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.078
|
Rat |
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.077
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.077
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
42 |
0.077
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.077
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.077
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.076
|
Human |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
2 |
0.076
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.075
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.075
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.074
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.074
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
55 |
0.073
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.073
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
22 |
0.073
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.072
|
Rat |
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.071
|
Human Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.071
|
|
|
|
angiogenesis
|
GO:0001525 |
53 |
0.070
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
126 |
0.070
|
|
|
|
gtp metabolic process
|
GO:0046039 |
72 |
0.070
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.070
|
Worm |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.070
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.070
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.069
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.068
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.068
|
Rat |
|
|
neuron projection development
|
GO:0031175 |
273 |
0.068
|
Fly |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.067
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.067
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.067
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.067
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.066
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.066
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.065
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.065
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.065
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
2 |
0.064
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.064
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.064
|
|
|
|
inflammatory response
|
GO:0006954 |
150 |
0.064
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.063
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.063
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.063
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.063
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.063
|
|
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.063
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
39 |
0.063
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.063
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.062
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.062
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.062
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.062
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.061
|
Human Mouse |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.061
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.061
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.061
|
Human |
|
|
renal system development
|
GO:0072001 |
67 |
0.060
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.060
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.060
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.060
|
Fly |
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.058
|
Human |
|
|
respiratory system development
|
GO:0060541 |
45 |
0.057
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.056
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.056
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.056
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.056
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.055
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.055
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.054
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
47 |
0.054
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.053
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
48 |
0.053
|
|
|
|
tissue regeneration
|
GO:0042246 |
36 |
0.053
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.053
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.052
|
Fly |
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.052
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.052
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.051
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.051
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.051
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.051
|
|
|
|
regeneration
|
GO:0031099 |
163 |
0.051
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.050
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
71 |
0.050
|
|
|
|
response to laminar fluid shear stress
|
GO:0034616 |
9 |
0.050
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.050
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
41 |
0.048
|
|
|
|
multicellular organism growth
|
GO:0035264 |
1 |
0.048
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
52 |
0.048
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.047
|
Human |
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.047
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.047
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
83 |
0.047
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
4 |
0.047
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.046
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.046
|
Human |
|
|
response to hydrogen peroxide
|
GO:0042542 |
89 |
0.046
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.045
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.045
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
194 |
0.045
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.045
|
|
|
|
tissue remodeling
|
GO:0048771 |
40 |
0.045
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.044
|
|
|
|
axon guidance
|
GO:0007411 |
24 |
0.044
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.044
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.044
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.044
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
66 |
0.044
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.043
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
53 |
0.043
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.043
|
|
|
|
response to bacterium
|
GO:0009617 |
200 |
0.043
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
27 |
0.043
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.043
|
Human Rat |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.043
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.042
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.042
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.042
|
Rat |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
52 |
0.042
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
42 |
0.042
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.042
|
|
|
|
receptor metabolic process
|
GO:0043112 |
18 |
0.041
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.041
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.041
|
Human |
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.041
|
Rat |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
2 |
0.040
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
26 |
0.040
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.040
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.040
|
Fly |
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.040
|
Rat |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.040
|
Rat |
|
|
response to electrical stimulus
|
GO:0051602 |
56 |
0.039
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.039
|
|
|
|
embryo development
|
GO:0009790 |
49 |
0.039
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
1 |
0.039
|
|
|
|
action potential
|
GO:0001508 |
54 |
0.039
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.039
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
2 |
0.039
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.038
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
20 |
0.038
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
4 |
0.038
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.038
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.038
|
Rat |
|
|
female pregnancy
|
GO:0007565 |
122 |
0.038
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.038
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
183 |
0.038
|
|
|
|
renal filtration
|
GO:0097205 |
10 |
0.037
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.037
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.037
|
Rat |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
35 |
0.037
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.037
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.037
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.036
|
|
|
|
endothelium development
|
GO:0003158 |
12 |
0.036
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.036
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.036
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.036
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.036
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.036
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
43 |
0.036
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.035
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.035
|
Human Rat |
|
|
response to estrogen
|
GO:0043627 |
232 |
0.035
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.035
|
|
|
|
urogenital system development
|
GO:0001655 |
78 |
0.035
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.035
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
77 |
0.034
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.034
|
Human |
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.034
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.034
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.034
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.034
|
Human |
|
|
transforming growth factor beta receptor complex assembly
|
GO:0007181 |
2 |
0.034
|
|
|
|
regulation of fc receptor mediated stimulatory signaling pathway
|
GO:0060368 |
3 |
0.033
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.033
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.033
|
Human |
|
|
axonogenesis
|
GO:0007409 |
71 |
0.033
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.033
|
|
|
|
leukocyte activation
|
GO:0045321 |
76 |
0.033
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.033
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.033
|
Rat |
|
|
glomerular epithelial cell differentiation
|
GO:0072311 |
2 |
0.033
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
42 |
0.033
|
Human |
|
|
epithelium development
|
GO:0060429 |
96 |
0.032
|
Mouse |
|
|
b cell mediated immunity
|
GO:0019724 |
4 |
0.032
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
28 |
0.032
|
|
|
|
dephosphorylation
|
GO:0016311 |
98 |
0.032
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.032
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.032
|
|
|
|
growth
|
GO:0040007 |
165 |
0.032
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.032
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.031
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.031
|
|
|
|
neuron projection guidance
|
GO:0097485 |
24 |
0.031
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
45 |
0.031
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
90 |
0.031
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.031
|
Rat |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
85 |
0.031
|
Worm |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.031
|
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.031
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.030
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.030
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.030
|
|
|
|
kidney development
|
GO:0001822 |
67 |
0.030
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.030
|
|
|
|
b cell differentiation
|
GO:0030183 |
2 |
0.030
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.030
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
30 |
0.029
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.029
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.029
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.029
|
Rat |
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.029
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.029
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.029
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
46 |
0.029
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
4 |
0.029
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.028
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
20 |
0.028
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.028
|
Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
53 |
0.028
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
58 |
0.028
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.028
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.028
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.028
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.028
|
|
|
|
hemopoiesis
|
GO:0030097 |
34 |
0.027
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
51 |
0.027
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
37 |
0.027
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.027
|
Mouse |
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.027
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.027
|
Human |
|
|
sequestering of calcium ion
|
GO:0051208 |
8 |
0.027
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.027
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
78 |
0.027
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.027
|
|
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
3 |
0.027
|
Worm |
|
|
sex differentiation
|
GO:0007548 |
113 |
0.027
|
|
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.026
|
|
|
|
gastrulation
|
GO:0007369 |
2 |
0.026
|
|
|
|
epithelium migration
|
GO:0090132 |
19 |
0.026
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.026
|
Human |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.026
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.026
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.026
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
39 |
0.026
|
Rat |
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
23 |
0.026
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.026
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.026
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.026
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
47 |
0.025
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.025
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.025
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
69 |
0.025
|
|
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.025
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
77 |
0.025
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
39 |
0.025
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
4 |
0.025
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
32 |
0.025
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.025
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
54 |
0.025
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.025
|
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.025
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
61 |
0.024
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.024
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
72 |
0.024
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
4 |
0.024
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
1 |
0.024
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.024
|
|
|
|
aging
|
GO:0007568 |
241 |
0.024
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.024
|
|
|
|
neuronal action potential
|
GO:0019228 |
35 |
0.024
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.024
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.024
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.023
|
Human |
|
|
gland development
|
GO:0048732 |
155 |
0.023
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
17 |
0.023
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
36 |
0.023
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.023
|
Rat |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.023
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.023
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.023
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.023
|
Rat |
|
|
sequestering of metal ion
|
GO:0051238 |
9 |
0.023
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.023
|
|
|
|
immune system development
|
GO:0002520 |
41 |
0.023
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
55 |
0.023
|
|
|
|
regulation of immune response
|
GO:0050776 |
55 |
0.023
|
Human |
|
|
response to insulin
|
GO:0032868 |
133 |
0.023
|
|
|
|
reproductive system development
|
GO:0061458 |
128 |
0.022
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.022
|
Worm |
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.022
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.022
|
|
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
3 |
0.022
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
60 |
0.022
|
|
|
|
regulation of skeletal muscle tissue regeneration
|
GO:0043416 |
2 |
0.022
|
|
|
|
lymphocyte migration
|
GO:0072676 |
3 |
0.022
|
|
|
|
regulation of ossification
|
GO:0030278 |
32 |
0.022
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.021
|
Rat |
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.021
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
41 |
0.021
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.021
|
|
|
|
regulation of defense response
|
GO:0031347 |
68 |
0.021
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.021
|
|
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
2 |
0.021
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
2 |
0.021
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.021
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
1 |
0.021
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
28 |
0.021
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.021
|
Rat |
|
|
negative regulation of innate immune response
|
GO:0045824 |
4 |
0.021
|
|
|
|
axis specification
|
GO:0009798 |
4 |
0.021
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.021
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
3 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
104 |
0.021
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.021
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
2 |
0.021
|
|
|
|
actin filament organization
|
GO:0007015 |
42 |
0.021
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.021
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
36 |
0.020
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
4 |
0.020
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.020
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
16 |
0.020
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
2 |
0.020
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
63 |
0.020
|
Rat |
