Rattus norvegicus

0 known processes

Prl3b1

Prolactin family 3, subfamily b, member 1

(Aliases: Csh2,Pl2,rPLII)

Prl3b1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of secretion by cell GO:1903530 208 0.477
regulation of secretion GO:0051046 224 0.274
secretion by cell GO:0032940 248 0.270
cation transmembrane transport GO:0098655 263 0.256
regulation of nervous system development GO:0051960 264 0.243
Rat
divalent metal ion transport GO:0070838 132 0.181
regulation of cellular localization GO:0060341 263 0.181
regulation of multicellular organismal development GO:2000026 376 0.162
Rat
response to radiation GO:0009314 137 0.155
Rat
positive regulation of cellular component organization GO:0051130 200 0.137
calcium ion transport GO:0006816 131 0.136
positive regulation of cell differentiation GO:0045597 217 0.133
Rat
positive regulation of signaling GO:0023056 270 0.132
Rat
circulatory system process GO:0003013 183 0.131
secretion GO:0046903 307 0.131
multicellular organism reproduction GO:0032504 233 0.129
Rat
positive regulation of nervous system development GO:0051962 178 0.127
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.116
Rat
metal ion transport GO:0030001 289 0.101
positive regulation of cell development GO:0010720 176 0.096
Rat
signal release GO:0023061 145 0.096
positive regulation of neurogenesis GO:0050769 165 0.096
Rat
response to mechanical stimulus GO:0009612 134 0.086
intracellular signal transduction GO:0035556 314 0.086
cellular response to lipid GO:0071396 201 0.083
choline transport GO:0015871 4 0.081
sensory organ development GO:0007423 74 0.080
regulation of neurotransmitter levels GO:0001505 42 0.080
cation transport GO:0006812 382 0.073
regulation of protein modification process GO:0031399 194 0.071
Rat
behavior GO:0007610 205 0.070
regulation of protein metabolic process GO:0051246 289 0.068
Rat
ion transmembrane transport GO:0034220 365 0.068
regulation of neurogenesis GO:0050767 247 0.067
Rat
regulation of molecular function GO:0065009 398 0.062
Rat
divalent inorganic cation transport GO:0072511 134 0.061
inorganic cation transmembrane transport GO:0098662 202 0.057
response to metal ion GO:0010038 253 0.057
response to nutrient levels GO:0031667 370 0.056
Rat
muscle system process GO:0003012 115 0.056
response to molecule of bacterial origin GO:0002237 194 0.055
Rat
response to inorganic substance GO:0010035 377 0.050
regulation of system process GO:0044057 208 0.049
regulation of metal ion transport GO:0010959 118 0.049
regulation of protein phosphorylation GO:0001932 183 0.049
Rat
positive regulation of cell communication GO:0010647 271 0.048
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.048
cell cell signaling GO:0007267 335 0.047
single organism reproductive process GO:0044702 297 0.047
Rat
regulation of hormone levels GO:0010817 187 0.045
Rat
cellular homeostasis GO:0019725 252 0.044
regulation of phosphate metabolic process GO:0019220 349 0.043
Rat
regulation of membrane potential GO:0042391 110 0.043
response to starvation GO:0042594 59 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.042
Rat
organic cyclic compound catabolic process GO:1901361 175 0.041
positive regulation of transport GO:0051050 245 0.040
regulation of neuron differentiation GO:0045664 208 0.040
negative regulation of multicellular organismal process GO:0051241 203 0.040
single organism behavior GO:0044708 130 0.040
nitrogen compound transport GO:0071705 229 0.038
ribose phosphate metabolic process GO:0019693 235 0.038
sexual reproduction GO:0019953 148 0.037
cellular response to external stimulus GO:0071496 118 0.037
regulation of cell development GO:0060284 263 0.036
Rat
calcium ion transmembrane transport GO:0070588 70 0.036
positive regulation of catalytic activity GO:0043085 184 0.035
Rat
positive regulation of developmental process GO:0051094 283 0.035
Rat
regulation of muscle system process GO:0090257 79 0.035
neurotransmitter transport GO:0006836 42 0.034
heart morphogenesis GO:0003007 3 0.034
protein oligomerization GO:0051259 191 0.034
regulation of ion transmembrane transporter activity GO:0032412 48 0.034
oxoacid metabolic process GO:0043436 290 0.033
cellular cation homeostasis GO:0030003 180 0.033
negative regulation of metabolic process GO:0009892 331 0.033
action potential GO:0001508 54 0.032
synaptic transmission GO:0007268 235 0.032
cell projection organization GO:0030030 302 0.032
heart contraction GO:0060047 57 0.031
regulation of cellular protein metabolic process GO:0032268 267 0.031
Rat
mapk cascade GO:0000165 140 0.031
anatomical structure morphogenesis GO:0009653 298 0.030
regulation of ion transmembrane transport GO:0034765 121 0.030
regulation of transmembrane transport GO:0034762 122 0.030
response to extracellular stimulus GO:0009991 380 0.030
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
rna biosynthetic process GO:0032774 380 0.029
reproduction GO:0000003 245 0.029
Rat
lipid metabolic process GO:0006629 283 0.029
Rat
regulation of transcription dna templated GO:0006355 374 0.029
negative regulation of response to stimulus GO:0048585 155 0.028
positive regulation of neuron differentiation GO:0045666 126 0.027
positive regulation of molecular function GO:0044093 230 0.027
Rat
regulation of catalytic activity GO:0050790 304 0.027
Rat
positive regulation of secretion GO:0051047 140 0.026
regulation of cell projection organization GO:0031344 175 0.026
transmembrane transport GO:0055085 412 0.026
regulation of mapk cascade GO:0043408 116 0.026
reproductive process GO:0022414 372 0.026
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.026
sensory perception GO:0007600 101 0.026
regulation of rna metabolic process GO:0051252 391 0.025
regulation of heart contraction GO:0008016 48 0.025
inflammatory response to antigenic stimulus GO:0002437 18 0.025
phasic smooth muscle contraction GO:0014821 3 0.025
regulation of body fluid levels GO:0050878 90 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
somatostatin receptor signaling pathway GO:0038169 4 0.025
positive regulation of gamma aminobutyric acid secretion GO:0014054 4 0.025
cellular response to oxygen containing compound GO:1901701 386 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
regulation of peptide transport GO:0090087 87 0.024
regulation of synaptic transmission GO:0050804 141 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
regulation of calcium ion transport GO:0051924 77 0.024
positive regulation of signal transduction GO:0009967 175 0.024
Rat
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.024
organophosphate catabolic process GO:0046434 148 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
response to nutrient GO:0007584 248 0.023
Rat
hormone secretion GO:0046879 115 0.023
activation of protein kinase activity GO:0032147 47 0.023
Rat
positive regulation of cell projection organization GO:0031346 111 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
regulation of protein kinase activity GO:0045859 105 0.022
Rat
nucleic acid templated transcription GO:0097659 379 0.022
multi organism reproductive process GO:0044703 262 0.022
Rat
regulation of transferase activity GO:0051338 123 0.022
Rat
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.021
negative regulation of cell development GO:0010721 82 0.021
response to oxygen levels GO:0070482 265 0.021
positive regulation of secretion by cell GO:1903532 128 0.021
response to lipopolysaccharide GO:0032496 191 0.021
Rat
cellular component morphogenesis GO:0032989 155 0.021
monocarboxylic acid transport GO:0015718 52 0.021
nucleotide metabolic process GO:0009117 279 0.021
tongue morphogenesis GO:0043587 3 0.021
regulation of cell differentiation GO:0045595 320 0.021
Rat
response to hypoxia GO:0001666 231 0.021
actin filament based process GO:0030029 86 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
regulation of transporter activity GO:0032409 50 0.020
chemical homeostasis GO:0048878 292 0.020
striated muscle contraction GO:0006941 44 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
learning or memory GO:0007611 90 0.020
regulation of phosphorylation GO:0042325 248 0.020
Rat
head development GO:0060322 247 0.020
multicellular organismal reproductive process GO:0048609 233 0.019
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
Rat
protein complex subunit organization GO:0071822 302 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
Rat
neuron projection development GO:0031175 273 0.019
peptide hormone secretion GO:0030072 84 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
cellular component biogenesis GO:0044085 368 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.019
regulation of signal transduction GO:0009966 318 0.019
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.018
sequestering of calcium ion GO:0051208 8 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of heart contraction GO:0045823 15 0.018
circadian sleep wake cycle process GO:0022410 21 0.018
organic anion transport GO:0015711 132 0.018
positive regulation of transferase activity GO:0051347 81 0.018
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
organic acid metabolic process GO:0006082 292 0.018
response to decreased oxygen levels GO:0036293 237 0.018
single organism organelle organization GO:1902589 180 0.018
organophosphate metabolic process GO:0019637 370 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
homeostatic process GO:0042592 331 0.018
spermatogenesis GO:0007283 99 0.018
negative regulation of nervous system development GO:0051961 79 0.017
small molecule catabolic process GO:0044282 59 0.017
indole containing compound metabolic process GO:0042430 11 0.017
cellular ketone metabolic process GO:0042180 51 0.017
rna metabolic process GO:0016070 406 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
Rat
proteolysis GO:0006508 175 0.017
eye development GO:0001654 50 0.017
cellular chemical homeostasis GO:0055082 247 0.017
cytoskeleton organization GO:0007010 111 0.017
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.017
cellular amine metabolic process GO:0044106 38 0.017
positive regulation of transcription dna templated GO:0045893 197 0.016
axis specification GO:0009798 4 0.016
somatostatin signaling pathway GO:0038170 4 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 7 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
cellular response to cgmp GO:0071321 2 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
Rat
anterior posterior pattern specification GO:0009952 1 0.016
amine metabolic process GO:0009308 38 0.016
peristalsis GO:0030432 2 0.016
neural crest cell migration GO:0001755 1 0.015
multicellular organismal response to stress GO:0033555 25 0.015
Rat
calcium ion homeostasis GO:0055074 162 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
response to light stimulus GO:0009416 52 0.015
Rat
neural crest cell differentiation GO:0014033 2 0.015
cyclic nucleotide metabolic process GO:0009187 80 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
ras protein signal transduction GO:0007265 29 0.015
neurological system process GO:0050877 219 0.015
glial cell differentiation GO:0010001 65 0.015
response to peptide GO:1901652 292 0.015
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
feeding behavior GO:0007631 53 0.015
wound healing GO:0042060 122 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
Rat
lipid modification GO:0030258 52 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
blood circulation GO:0008015 183 0.015
insulin secretion GO:0030073 69 0.015
response to cold GO:0009409 29 0.014
response to wounding GO:0009611 254 0.014
positive regulation of ion transport GO:0043270 94 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
central nervous system development GO:0007417 311 0.014
associative learning GO:0008306 19 0.014
positive regulation of transmembrane transport GO:0034764 25 0.014
cellular response to acid chemical GO:0071229 75 0.014
positive regulation of ion transmembrane transport GO:0034767 24 0.014
learning GO:0007612 33 0.014
cellular ion homeostasis GO:0006873 184 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
axon ensheathment GO:0008366 40 0.014
response to estrogen GO:0043627 232 0.014
Rat
positive regulation of response to food GO:0032097 3 0.014
transmission of nerve impulse GO:0019226 42 0.014
cellular response to retinoic acid GO:0071300 27 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
regulation of catabolic process GO:0009894 113 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
regulation of amine transport GO:0051952 54 0.013
cognition GO:0050890 92 0.013
camera type eye development GO:0043010 48 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
eye morphogenesis GO:0048592 4 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of protein serine threonine kinase activity GO:0071900 64 0.013
response to alkaloid GO:0043279 132 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
sodium ion transport GO:0006814 82 0.013
regulation of neurotransmitter transport GO:0051588 21 0.013
response to calcium ion GO:0051592 59 0.013
response to cytokine GO:0034097 215 0.013
Rat
heart process GO:0003015 57 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
retina morphogenesis in camera type eye GO:0060042 1 0.013
multicellular organismal signaling GO:0035637 44 0.013
regulation of homotypic cell cell adhesion GO:0034110 4 0.013
tissue development GO:0009888 252 0.013
hormone transport GO:0009914 121 0.012
detection of stimulus GO:0051606 24 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
regulation of kinase activity GO:0043549 117 0.012
Rat
cellular response to stress GO:0033554 269 0.012
metal ion homeostasis GO:0055065 186 0.012
developmental process involved in reproduction GO:0003006 159 0.012
heterocycle catabolic process GO:0046700 167 0.012
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.012
neurotransmitter secretion GO:0007269 33 0.012
locomotory exploration behavior GO:0035641 1 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
Rat
peptide secretion GO:0002790 86 0.012
thyroid gland development GO:0030878 1 0.012
regulation of blood circulation GO:1903522 110 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
Rat
lipid transport GO:0006869 61 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
response to retinoic acid GO:0032526 63 0.012
male gamete generation GO:0048232 99 0.012
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
camera type eye morphogenesis GO:0048593 2 0.012
alcohol metabolic process GO:0006066 77 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.012
neural crest cell development GO:0014032 2 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
catabolic process GO:0009056 351 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
sleep GO:0030431 30 0.011
negative regulation of cell communication GO:0010648 158 0.011
negative regulation of developmental process GO:0051093 125 0.011
ensheathment of neurons GO:0007272 40 0.011
second messenger mediated signaling GO:0019932 51 0.011
cardiac muscle contraction GO:0060048 27 0.011
response to cgmp GO:0070305 3 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
negative regulation of defecation GO:2000293 1 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of blood pressure GO:0008217 83 0.011
regulation of cardiac muscle contraction GO:0055117 17 0.011
purine containing compound metabolic process GO:0072521 253 0.011
regulation of dna metabolic process GO:0051052 60 0.011
dna metabolic process GO:0006259 96 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
urinary bladder smooth muscle contraction GO:0014832 4 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
gamete generation GO:0007276 124 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
negative regulation of cellular component organization GO:0051129 83 0.010
serotonin metabolic process GO:0042428 3 0.010
peptide transport GO:0015833 97 0.010
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.010
inflammatory response GO:0006954 150 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
Rat
appendage morphogenesis GO:0035107 4 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
cell type specific apoptotic process GO:0097285 134 0.010
development of primary sexual characteristics GO:0045137 107 0.010
neuron development GO:0048666 286 0.010
neuron differentiation GO:0030182 368 0.010
cell morphogenesis GO:0000902 142 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
embryonic pattern specification GO:0009880 1 0.010
tube development GO:0035295 89 0.010
Rat
regulation of synaptic transmission gabaergic GO:0032228 17 0.010

Prl3b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.057
sensory system disease DOID:0050155 0 0.025
eye and adnexa disease DOID:1492 0 0.025
eye disease DOID:5614 0 0.025
retinal disease DOID:5679 0 0.011
urinary system disease DOID:18 0 0.011