|
|
negative regulation of serine type endopeptidase activity
|
GO:1900004 |
1 |
0.813
|
|
|
|
negative regulation of serine type peptidase activity
|
GO:1902572 |
1 |
0.636
|
|
|
|
response to nutrient
|
GO:0007584 |
248 |
0.616
|
Rat |
|
|
extracellular matrix constituent secretion
|
GO:0070278 |
4 |
0.562
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.552
|
|
|
|
regulation of extracellular matrix constituent secretion
|
GO:0003330 |
2 |
0.537
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
16 |
0.520
|
|
|
|
regulation of serine type peptidase activity
|
GO:1902571 |
1 |
0.474
|
|
|
|
positive regulation of extracellular matrix constituent secretion
|
GO:0003331 |
2 |
0.440
|
|
|
|
positive regulation of extracellular matrix organization
|
GO:1903055 |
4 |
0.433
|
|
|
|
positive regulation of coagulation
|
GO:0050820 |
5 |
0.401
|
Rat |
|
|
regulation of serine type endopeptidase activity
|
GO:1900003 |
1 |
0.389
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.385
|
Rat |
|
|
immune response
|
GO:0006955 |
104 |
0.354
|
|
|
|
response to vitamin b6
|
GO:0034516 |
1 |
0.344
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.329
|
Rat |
|
|
reproductive process
|
GO:0022414 |
372 |
0.315
|
|
|
|
regeneration
|
GO:0031099 |
163 |
0.294
|
Rat |
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.285
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.282
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.266
|
|
|
|
protein maturation
|
GO:0051604 |
68 |
0.264
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
50 |
0.261
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.258
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.255
|
|
|
|
response to muscle activity involved in regulation of muscle adaptation
|
GO:0014873 |
2 |
0.254
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.243
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.238
|
Rat |
|
|
inflammatory response
|
GO:0006954 |
150 |
0.234
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.234
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.221
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.221
|
|
|
|
protein processing
|
GO:0016485 |
68 |
0.220
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.219
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.213
|
|
|
|
plasminogen activation
|
GO:0031639 |
2 |
0.208
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
54 |
0.204
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.199
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.199
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.196
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.195
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.195
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.193
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.192
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.191
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.190
|
|
|
|
fibrinolysis
|
GO:0042730 |
2 |
0.189
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
14 |
0.184
|
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.183
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
90 |
0.183
|
Mouse Rat |
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.182
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.182
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.181
|
|
|
|
regulation of protein processing
|
GO:0070613 |
50 |
0.181
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.178
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.175
|
Rat |
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.174
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
83 |
0.173
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.172
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.167
|
Human |
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.166
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.165
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.163
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.160
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.160
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.159
|
Rat |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.156
|
|
|
|
regulation of excretion
|
GO:0044062 |
21 |
0.155
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.154
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.153
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.152
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.152
|
Mouse Rat |
|
|
immune system process
|
GO:0002376 |
204 |
0.151
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.151
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
68 |
0.149
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.148
|
|
|
|
response to camp
|
GO:0051591 |
91 |
0.147
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.143
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.141
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.139
|
|
|
|
response to methanol
|
GO:0033986 |
1 |
0.139
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.135
|
Rat |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.134
|
|
|
|
renin angiotensin regulation of aldosterone production
|
GO:0002018 |
3 |
0.132
|
|
|
|
regulation of fibrinolysis
|
GO:0051917 |
2 |
0.130
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.129
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.128
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.126
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.126
|
|
|
|
positive regulation of blood coagulation
|
GO:0030194 |
4 |
0.125
|
Rat |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.125
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.122
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.122
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.122
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
38 |
0.122
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.121
|
|
|
|
neurological system process involved in regulation of systemic arterial blood pressure
|
GO:0001976 |
3 |
0.119
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.119
|
|
|
|
renal system process
|
GO:0003014 |
40 |
0.118
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.118
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.116
|
|
|
|
brain renin angiotensin system
|
GO:0002035 |
3 |
0.115
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.114
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.113
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.112
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.112
|
Human |
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.112
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
47 |
0.110
|
|
|
|
response to bacterium
|
GO:0009617 |
200 |
0.109
|
|
|
|
artery smooth muscle contraction
|
GO:0014824 |
4 |
0.109
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.108
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.108
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.108
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.108
|
Mouse |
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.108
|
|
|
|
response to vitamin
|
GO:0033273 |
131 |
0.106
|
Rat |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.105
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.105
|
Mouse Rat |
|
|
tissue development
|
GO:0009888 |
252 |
0.104
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.104
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.103
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.103
|
Human |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.102
|
|
|
|
liver development
|
GO:0001889 |
90 |
0.102
|
|
|
|
calcium ion transport
|
GO:0006816 |
131 |
0.102
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.100
|
Rat |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.098
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.097
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.096
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.095
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.095
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.094
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
49 |
0.094
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.093
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
77 |
0.092
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.091
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
49 |
0.091
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.090
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.090
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.089
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.089
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.089
|
|
|
|
cellular sodium ion homeostasis
|
GO:0006883 |
4 |
0.089
|
|
|
|
response to triglyceride
|
GO:0034014 |
3 |
0.088
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
90 |
0.088
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
47 |
0.088
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.084
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.083
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
69 |
0.083
|
|
|
|
response to chromate
|
GO:0046687 |
3 |
0.083
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.083
|
|
|
|
aging
|
GO:0007568 |
241 |
0.082
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.082
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.079
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.079
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.078
|
|
|
|
angiotensin mediated drinking behavior
|
GO:0003051 |
2 |
0.077
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.077
|
|
|
|
organ regeneration
|
GO:0031100 |
101 |
0.077
|
Rat |
|
|
actin filament based process
|
GO:0030029 |
86 |
0.076
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.076
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.076
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.076
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.075
|
|
|
|
renal sodium excretion
|
GO:0035812 |
20 |
0.075
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.075
|
Human |
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.074
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.073
|
|
|
|
nuclear transport
|
GO:0051169 |
49 |
0.073
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.073
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.073
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.073
|
Mouse Rat |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.073
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
1 |
0.073
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.071
|
|
|
|
tonic smooth muscle contraction
|
GO:0014820 |
4 |
0.070
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
36 |
0.070
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.070
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
37 |
0.069
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.069
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
37 |
0.069
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
194 |
0.068
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.067
|
|
|
|
blood vessel development
|
GO:0001568 |
69 |
0.066
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.065
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.064
|
Human |
|
|
single organism behavior
|
GO:0044708 |
130 |
0.064
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.064
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.064
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
106 |
0.064
|
Mouse Rat |
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.063
|
|
|
|
regulation of wound healing
|
GO:0061041 |
14 |
0.063
|
Mouse Rat |
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.063
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.062
|
Rat |
|
|
phenol containing compound metabolic process
|
GO:0018958 |
30 |
0.062
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.062
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.062
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.061
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.059
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.059
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.058
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.057
|
|
|
|
amine transport
|
GO:0015837 |
57 |
0.057
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.056
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.056
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.056
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.056
|
Rat |
|
|
intracellular transport
|
GO:0046907 |
185 |
0.056
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.056
|
|
|
|
regulation of plasminogen activation
|
GO:0010755 |
2 |
0.056
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.055
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.055
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.055
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.055
|
|
|
|
hepatocyte proliferation
|
GO:0072574 |
3 |
0.055
|
|
|
|
negative regulation of fibrinolysis
|
GO:0051918 |
2 |
0.054
|
|
|
|
response to organophosphorus
|
GO:0046683 |
102 |
0.054
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.053
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.053
|
Mouse |
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.053
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.052
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.051
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.051
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
55 |
0.051
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
41 |
0.051
|
|
|
|
extracellular structure organization
|
GO:0043062 |
13 |
0.050
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.050
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
122 |
0.050
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.049
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.049
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.048
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.048
|
|
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.048
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
13 |
0.048
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.047
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.047
|
|
|
|
response to corticosterone
|
GO:0051412 |
40 |
0.046
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.046
|
|
|
|
negative regulation of endothelial cell proliferation
|
GO:0001937 |
5 |
0.046
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.046
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
44 |
0.046
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.046
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
77 |
0.045
|
|
|
|
store operated calcium entry
|
GO:0002115 |
2 |
0.045
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
59 |
0.045
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
98 |
0.045
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.045
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
103 |
0.045
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.045
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.044
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
26 |
0.044
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
5 |
0.044
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.044
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.044
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.044
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.044
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.044
|
|
|
|
positive regulation of hemostasis
|
GO:1900048 |
4 |
0.043
|
Rat |
|
|
growth
|
GO:0040007 |
165 |
0.043
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.043
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.042
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.042
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.042
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.042
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
30 |
0.042
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
13 |
0.042
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.042
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
58 |
0.042
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.041
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.041
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.041
|
|
|
|
kidney development
|
GO:0001822 |
67 |
0.041
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.041
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.040
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
16 |
0.040
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.040
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.040
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.040
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.040
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.039
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.039
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
66 |
0.039
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.039
|
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
14 |
0.039
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.039
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.038
|
|
|
|
response to interferon gamma
|
GO:0034341 |
20 |
0.038
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
120 |
0.038
|
|
|
|
protein import into nucleus
|
GO:0006606 |
35 |
0.037
|
|
|
|
phenol containing compound biosynthetic process
|
GO:0046189 |
9 |
0.037
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
63 |
0.037
|
|
|
|
regulation of growth
|
GO:0040008 |
105 |
0.037
|
|
|
|
regulation of renal sodium excretion
|
GO:0035813 |
20 |
0.037
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.037
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.037
|
|
|
|
hormone metabolic process
|
GO:0042445 |
69 |
0.037
|
|
|
|
endocrine process
|
GO:0050886 |
32 |
0.036
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.036
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.036
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.036
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.036
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
35 |
0.036
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.036
|
|
|
|
folic acid containing compound metabolic process
|
GO:0006760 |
10 |
0.035
|
|
|
|
urogenital system development
|
GO:0001655 |
78 |
0.035
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.035
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.035
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.035
|
|
|
|
innate immune response
|
GO:0045087 |
35 |
0.034
|
|
|
|
angiogenesis
|
GO:0001525 |
53 |
0.034
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
16 |
0.034
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.034
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.034
|
|
|
|
renal system development
|
GO:0072001 |
67 |
0.034
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.034
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
9 |
0.033
|
Mouse Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
48 |
0.033
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.033
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.033
|
Rat |
|
|
catecholamine secretion
|
GO:0050432 |
33 |
0.033
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.033
|
|
|
|
acrosome assembly
|
GO:0001675 |
3 |
0.032
|
|
|
|
response to insulin
|
GO:0032868 |
133 |
0.032
|
|
|
|
acute inflammatory response
|
GO:0002526 |
58 |
0.032
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
71 |
0.032
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
8 |
0.032
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.032
|
|
|
|
catecholamine transport
|
GO:0051937 |
37 |
0.032
|
|
|
|
excretion
|
GO:0007588 |
24 |
0.032
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.031
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
15 |
0.031
|
|
|
|
regulation of cell growth
|
GO:0001558 |
85 |
0.031
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.031
|
|
|
|
nuclear import
|
GO:0051170 |
35 |
0.031
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.031
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.031
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
73 |
0.031
|
|
|
|
response to glucose
|
GO:0009749 |
136 |
0.031
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
69 |
0.031
|
Mouse Rat |
|
|
negative regulation of vasculature development
|
GO:1901343 |
11 |
0.031
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.030
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.030
|
Rat |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.030
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
1 |
0.030
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
45 |
0.030
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
67 |
0.030
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.029
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.029
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
48 |
0.029
|
Rat |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.029
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.029
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
9 |
0.029
|
Mouse Rat |
|
|
smooth muscle cell proliferation
|
GO:0048659 |
77 |
0.029
|
|
|
|
response to platinum ion
|
GO:0070541 |
4 |
0.029
|
|
|
|
sodium ion homeostasis
|
GO:0055078 |
23 |
0.029
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.028
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.028
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
35 |
0.028
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.028
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.028
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.028
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.028
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
87 |
0.028
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.028
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
43 |
0.028
|
|
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.028
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
78 |
0.027
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.027
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
49 |
0.027
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.027
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.027
|
|
|
|
anion transport
|
GO:0006820 |
178 |
0.027
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
44 |
0.027
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.027
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.027
|
|
|
|
response to food
|
GO:0032094 |
27 |
0.027
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.027
|
|
|
|
response to retinoic acid
|
GO:0032526 |
63 |
0.027
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.027
|
|
|
|
drinking behavior
|
GO:0042756 |
11 |
0.027
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.027
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.026
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.026
|
|
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.026
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
34 |
0.026
|
Rat |
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.026
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.026
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.026
|
|
|
|
actin filament organization
|
GO:0007015 |
42 |
0.026
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.026
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.026
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
44 |
0.025
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.025
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.025
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
61 |
0.025
|
|
|
|
cardiac cell development
|
GO:0055006 |
16 |
0.025
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.025
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.025
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.025
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
42 |
0.025
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.025
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
51 |
0.025
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.025
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.025
|
|
|
|
cell growth
|
GO:0016049 |
104 |
0.025
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.025
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
48 |
0.024
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.024
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.024
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.024
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
21 |
0.024
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.024
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
83 |
0.023
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
22 |
0.023
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.023
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.023
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.023
|
|
|
|
cellular response to camp
|
GO:0071320 |
26 |
0.023
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.023
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.023
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
15 |
0.023
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.023
|
|
|
|
positive regulation of hepatocyte differentiation
|
GO:0070368 |
2 |
0.023
|
|
|
|
glycine metabolic process
|
GO:0006544 |
7 |
0.023
|
|
|
|
regulation of coagulation
|
GO:0050818 |
11 |
0.023
|
Mouse Rat |
|
|
carbohydrate homeostasis
|
GO:0033500 |
75 |
0.022
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.022
|
|
|
|
positive regulation of renal sodium excretion
|
GO:0035815 |
10 |
0.022
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.022
|
|
|
|
urea cycle
|
GO:0000050 |
5 |
0.022
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.022
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
92 |
0.022
|
|
|
|
response to activity
|
GO:0014823 |
73 |
0.022
|
|
|
|
fertilization
|
GO:0009566 |
3 |
0.022
|
|
|
|
head development
|
GO:0060322 |
247 |
0.022
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.022
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
111 |
0.022
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.022
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.021
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.021
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.021
|
|
|
|
heart development
|
GO:0007507 |
72 |
0.021
|
|
|
|
renal system process involved in regulation of systemic arterial blood pressure
|
GO:0003071 |
14 |
0.021
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.021
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.021
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
1 |
0.021
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
27 |
0.021
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.021
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.020
|
|
|
|
positive regulation of fatty acid beta oxidation
|
GO:0032000 |
4 |
0.020
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
35 |
0.020
|
|
|
|
gliogenesis
|
GO:0042063 |
93 |
0.020
|
|
|
|
protein import
|
GO:0017038 |
37 |
0.020
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.020
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
6 |
0.020
|
Mouse |
|
|
response to interleukin 1
|
GO:0070555 |
55 |
0.020
|
|
|
|
positive regulation of blood pressure
|
GO:0045777 |
31 |
0.020
|
|
|
|
cytokine production
|
GO:0001816 |
61 |
0.020
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.020
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.020
|
|
|
|
naphthalene containing compound metabolic process
|
GO:0090420 |
2 |
0.019
|
|
|
|
monoamine transport
|
GO:0015844 |
43 |
0.019
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.019
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.019
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.019
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
52 |
0.019
|
|
|
|
single fertilization
|
GO:0007338 |
3 |
0.019
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
87 |
0.019
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.019
|
|
|
|
liver morphogenesis
|
GO:0072576 |
3 |
0.019
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
62 |
0.018
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.018
|
|
|
|
tissue remodeling
|
GO:0048771 |
40 |
0.018
|
|
|
|
alpha amino acid biosynthetic process
|
GO:1901607 |
23 |
0.018
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
52 |
0.018
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.018
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.018
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.018
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.018
|
|
|
|
protein targeting
|
GO:0006605 |
61 |
0.018
|
|
|
|
muscle structure development
|
GO:0061061 |
87 |
0.018
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
20 |
0.018
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
80 |
0.018
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.018
|
|
|
|
uterine smooth muscle contraction
|
GO:0070471 |
10 |
0.018
|
|
|
|
cellular amino acid catabolic process
|
GO:0009063 |
21 |
0.018
|
|
|
|
toxin metabolic process
|
GO:0009404 |
9 |
0.017
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.017
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.017
|
|
|
|
maintenance of location
|
GO:0051235 |
17 |
0.017
|
|
|
|
response to lead ion
|
GO:0010288 |
33 |
0.017
|
|
