Rattus norvegicus

80 known processes

Prps1

phosphoribosyl pyrophosphate synthetase 1

Prps1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.301
regulation of nucleic acid templated transcription GO:1903506 380 0.189
transcription dna templated GO:0006351 377 0.175
nucleic acid templated transcription GO:0097659 379 0.173
rna metabolic process GO:0016070 406 0.165
regulation of rna biosynthetic process GO:2001141 381 0.149
regulation of transcription dna templated GO:0006355 374 0.147
nucleosome organization GO:0034728 1 0.143
rna biosynthetic process GO:0032774 380 0.129
organonitrogen compound biosynthetic process GO:1901566 167 0.108
positive regulation of transcription dna templated GO:0045893 197 0.102
macromolecular complex subunit organization GO:0043933 339 0.097
cellular component assembly GO:0022607 360 0.090
organelle organization GO:0006996 266 0.086
negative regulation of metabolic process GO:0009892 331 0.078
single organism reproductive process GO:0044702 297 0.068
sexual reproduction GO:0019953 148 0.065
reproductive process GO:0022414 372 0.065
cofactor metabolic process GO:0051186 95 0.065
multicellular organismal reproductive process GO:0048609 233 0.064
protein localization GO:0008104 191 0.063
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.062
secretion GO:0046903 307 0.059
negative regulation of cellular metabolic process GO:0031324 281 0.059
protein oligomerization GO:0051259 191 0.058
protein localization to organelle GO:0033365 57 0.056
intracellular protein transport GO:0006886 79 0.056
cellular component biogenesis GO:0044085 368 0.052
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.052
gamete generation GO:0007276 124 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.050
single organism cellular localization GO:1902580 102 0.048
nucleoside phosphate biosynthetic process GO:1901293 102 0.048
cellular protein localization GO:0034613 122 0.047
organic substance catabolic process GO:1901575 316 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.046
purine containing compound metabolic process GO:0072521 253 0.046
cytoplasmic transport GO:0016482 115 0.045
positive regulation of gene expression GO:0010628 244 0.045
protein targeting GO:0006605 61 0.045
cellular catabolic process GO:0044248 295 0.045
multi organism reproductive process GO:0044703 262 0.044
regulation of cell proliferation GO:0042127 359 0.044
regeneration GO:0031099 163 0.044
protein complex subunit organization GO:0071822 302 0.043
macromolecule localization GO:0033036 252 0.043
protein complex biogenesis GO:0070271 263 0.043
developmental process involved in reproduction GO:0003006 159 0.043
negative regulation of gene expression GO:0010629 199 0.040
defense response GO:0006952 194 0.040
secretion by cell GO:0032940 248 0.039
purine containing compound biosynthetic process GO:0072522 85 0.039
positive regulation of rna metabolic process GO:0051254 203 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
reproduction GO:0000003 245 0.037
anatomical structure morphogenesis GO:0009653 298 0.036
Fly
nucleoside monophosphate biosynthetic process GO:0009124 28 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.035
multicellular organism reproduction GO:0032504 233 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
response to external biotic stimulus GO:0043207 221 0.034
nucleotide biosynthetic process GO:0009165 98 0.033
chromatin assembly or disassembly GO:0006333 1 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
homeostatic process GO:0042592 331 0.032
protein phosphorylation GO:0006468 345 0.032
cellular macromolecule localization GO:0070727 122 0.031
tissue development GO:0009888 252 0.031
protein complex assembly GO:0006461 263 0.030
cellular response to endogenous stimulus GO:0071495 377 0.029
intracellular transport GO:0046907 185 0.029
embryonic pattern specification GO:0009880 1 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
spermatogenesis GO:0007283 99 0.028
response to other organism GO:0051707 220 0.028
protein transport GO:0015031 132 0.028
macromolecular complex assembly GO:0065003 273 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.028
negative regulation of transcription dna templated GO:0045892 116 0.027
regulation of protein metabolic process GO:0051246 289 0.027
response to nutrient levels GO:0031667 370 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.025
response to extracellular stimulus GO:0009991 380 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
organelle localization GO:0051640 55 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.024
ribonucleotide biosynthetic process GO:0009260 85 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.024
alpha amino acid metabolic process GO:1901605 71 0.023
regulation of phosphorylation GO:0042325 248 0.023
response to nutrient GO:0007584 248 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
cellular amino acid catabolic process GO:0009063 21 0.023
positive regulation of cellular component movement GO:0051272 102 0.022
male gamete generation GO:0048232 99 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
cell cell signaling GO:0007267 335 0.021
positive regulation of signaling GO:0023056 270 0.021
regulation of signal transduction GO:0009966 318 0.021
ribonucleoside monophosphate metabolic process GO:0009161 88 0.020
organic acid metabolic process GO:0006082 292 0.020
Human
purine ribonucleotide biosynthetic process GO:0009152 81 0.020
inflammatory response GO:0006954 150 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
oxoacid metabolic process GO:0043436 290 0.020
programmed cell death GO:0012501 392 0.019
exocytosis GO:0006887 60 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.018
cellular macromolecular complex assembly GO:0034622 58 0.018
immune system process GO:0002376 204 0.017
chemosensory behavior GO:0007635 2 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
establishment of protein localization GO:0045184 141 0.017
aging GO:0007568 241 0.017
cell part morphogenesis GO:0032990 123 0.017
chromosome segregation GO:0007059 2 0.017
signal release GO:0023061 145 0.016
single organism biosynthetic process GO:0044711 342 0.016
dephosphorylation GO:0016311 98 0.016
ribonucleoside biosynthetic process GO:0042455 25 0.016
gland development GO:0048732 155 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
regulation of molecular function GO:0065009 398 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
purine nucleotide biosynthetic process GO:0006164 83 0.016
early endosome to late endosome transport GO:0045022 2 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
regulation of cellular localization GO:0060341 263 0.016
regulation of cellular component organization GO:0051128 368 0.016
positive regulation of secretion GO:0051047 140 0.015
catabolic process GO:0009056 351 0.015
cell activation involved in immune response GO:0002263 16 0.015
response to hypoxia GO:0001666 231 0.015
neurological system process GO:0050877 219 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
axis specification GO:0009798 4 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.015
dicarboxylic acid catabolic process GO:0043649 1 0.015
cation transport GO:0006812 382 0.015
histamine production involved in inflammatory response GO:0002349 3 0.015
single organism intracellular transport GO:1902582 166 0.015
negative regulation of molecular function GO:0044092 133 0.015
intracellular signal transduction GO:0035556 314 0.015
cellular component morphogenesis GO:0032989 155 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.014
response to bacterium GO:0009617 200 0.014
regulation of protein modification process GO:0031399 194 0.014
negative regulation of protein phosphorylation GO:0001933 44 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
nucleoside metabolic process GO:0009116 179 0.014
amine metabolic process GO:0009308 38 0.014
calcium ion dependent exocytosis GO:0017156 16 0.014
response to vitamin GO:0033273 131 0.014
cellular amine metabolic process GO:0044106 38 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
olfactory behavior GO:0042048 2 0.013
regulation of protein localization GO:0032880 81 0.013
sulfur compound metabolic process GO:0006790 70 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
coenzyme metabolic process GO:0006732 86 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
response to growth factor GO:0070848 189 0.013
mrna metabolic process GO:0016071 20 0.013
mast cell mediated immunity GO:0002448 10 0.013
immune response GO:0006955 104 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
response to decreased oxygen levels GO:0036293 237 0.012
bmp signaling pathway GO:0030509 4 0.012
macromolecule catabolic process GO:0009057 58 0.012
nucleotide metabolic process GO:0009117 279 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
response to biotic stimulus GO:0009607 226 0.012
myeloid leukocyte mediated immunity GO:0002444 12 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
axon development GO:0061564 96 0.012
embryonic axis specification GO:0000578 1 0.011
regulation of secretion GO:0051046 224 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
positive regulation of transport GO:0051050 245 0.011
maintenance of location GO:0051235 17 0.011
circulatory system development GO:0072359 134 0.011
protein dephosphorylation GO:0006470 38 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
cellular response to peptide GO:1901653 133 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
leukocyte activation GO:0045321 76 0.010
lysosome localization GO:0032418 10 0.010
rhythmic process GO:0048511 156 0.010
cofactor biosynthetic process GO:0051188 28 0.010
regulation of protein transport GO:0051223 68 0.010
brain development GO:0007420 247 0.010
regulation of secretion by cell GO:1903530 208 0.010
regulation of hormone levels GO:0010817 187 0.010
regulation of cellular component movement GO:0051270 150 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
regulation of locomotion GO:0040012 148 0.010
endomembrane system organization GO:0010256 48 0.010
single organism catabolic process GO:0044712 283 0.010
cellular response to external stimulus GO:0071496 118 0.010
response to starvation GO:0042594 59 0.010

Prps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.051
muscular disease DOID:0080000 0 0.051
muscular dystrophy DOID:9884 0 0.051
disease of anatomical entity DOID:7 0 0.051
Human
muscle tissue disease DOID:66 0 0.051
musculoskeletal system disease DOID:17 0 0.051
nervous system disease DOID:863 0 0.019
Human
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018